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1. 发明授权

US06887231B2 Control program for a device for photorefractive corneal surgery of the eye 有权
$Control program for a device for photorefractive corneal surgery of the eye$
标题翻译：用于眼睛光折射角膜手术的装置的控制程序
公开(公告)号：US06887231B2
公开(公告)日：2005-05-03
申请号：US10031107
申请日：2001-05-03
申请人： Michael Mrochen , Maik Kaemmerer , Theo Seiler
发明人： Michael Mrochen , Maik Kaemmerer , Theo Seiler
IPC分类号： A61F9/01 , A61F9/013 , A61B18/18
CPC分类号： A61F9/00806 , A61F9/00817 , A61F9/013 , A61F2009/00848 , A61F2009/00853 , A61F2009/00872 , A61F2009/00887
摘要： In a control program, according to which a laser-beam spot is guided, while being controlled with respect to position and time, over a cornea to be corrected photorefractively, so as to ablate a predetermined ablation profile therefrom, the effect of the angle between the laser earn and the corneal surface on the energy density of the laser-beam spot incident on the corneal surface and/or on the fraction of the laser-beam energy incident on the corneal surface which is reflected away, is taken into account when generating the control program.
摘要翻译：在控制程序中，根据该控制程序，激光束点在被相对于位置和时间被控制的同时被导光，通过光折射校正的角膜被引导，从而从其中消除预定的消融轮廓，入射到角膜表面上的激光束斑点的能量密度和/或入射到被反射的角膜表面上的激光束能量的分数上的激光获得和角膜表面在产生时被考虑控制程序。

2. 发明授权

US07544194B2 Method of generating a control program for a device for photorefractive corneal surgery of the eye 有权
$Method of generating a control program for a device for photorefractive corneal surgery of the eye$
标题翻译：产生用于眼睛光折射角膜手术的装置的控制程序的方法
公开(公告)号：US07544194B2
公开(公告)日：2009-06-09
申请号：US11109180
申请日：2005-04-19
申请人： Michael Mrochen , Maik Kaemmerer , Theo Seiler
发明人： Michael Mrochen , Maik Kaemmerer , Theo Seiler
IPC分类号： A61B18/18
CPC分类号： A61F9/00806 , A61F9/00817 , A61F9/013 , A61F2009/00848 , A61F2009/00853 , A61F2009/00872 , A61F2009/00887
摘要： In a method of generating a control program, according to which a laser-beam spot is guided, while being controlled with respect to position and time, over a cornea to be corrected photorefractively, so as to ablate a predetermined ablation profile therefrom, the effect of the angle between the laser beam and the corneal surface on the energy density of the laser-beam spot incident on the corneal surface and/or on the fraction of the laser-beam energy incident on the corneal surface which is reflected away, is taken into account when generating the control program.
摘要翻译：在产生控制程序的方法中，根据该方法，激光束点在被相对于位置和时间被控制的同时被引导，通过光折射来校正角膜，从而消除预定的消融轮廓，效果激光束和角膜表面之间的角度对入射到角膜表面上的激光束斑点的能量密度和/或入射到被反射的角膜表面上的激光束能量的分数进行采集在生成控制程序时考虑到。

3. 发明申请

US20050187540A1 Method of generating a control program for a device for photorefractive corneal surgery of the eye 有权
$Method of generating a control program for a device for photorefractive corneal surgery of the eye$
标题翻译：产生用于眼睛光折射角膜手术的装置的控制程序的方法
公开(公告)号：US20050187540A1
公开(公告)日：2005-08-25
申请号：US11109180
申请日：2005-04-19
申请人： Michael Mrochen , Maik Kaemmerer , Theo Seiler
发明人： Michael Mrochen , Maik Kaemmerer , Theo Seiler
IPC分类号： A61F9/01 , A61F9/013 , A61B18/20
CPC分类号： A61F9/00806 , A61F9/00817 , A61F9/013 , A61F2009/00848 , A61F2009/00853 , A61F2009/00872 , A61F2009/00887
摘要： Method of generating a control program for a device for photorefractive corneal surgery of the eye In a method of generating a control program, according to which a laser-beam spot is guided, while being controlled with respect to position and time, over a cornea to be corrected photorefractively, so as to ablate a predetermined ablation profile therefrom, the effect of the angle between the laser beam and the corneal surface on the energy density of the laser-beam spot incident on the corneal surface and/or on the fraction of the laser-beam energy incident on the corneal surface which is reflected away, is taken into account when generating the control program.
摘要翻译：产生用于眼睛的光折射角膜手术的装置的控制程序的方法在生成控制程序的方法中，根据该方法，在相对于位置和时间被控制的同时，通过角膜到光折射校正，以消除预定的消融轮廓，激光束和角膜表面之间的角度对入射在角膜表面上的激光束斑点的能量密度和/或角膜表面的部分上的影响在产生控制程序时，考虑入射在被反射的角膜表面上的激光束能量。

4. 发明授权

US06530917B1 Device for photorefractive cornea surgery in higher-order visual disorders 有权
$Device for photorefractive cornea surgery in higher-order visual disorders$
标题翻译：用于高阶视觉障碍的屈光角膜手术的装置
公开(公告)号：US06530917B1
公开(公告)日：2003-03-11
申请号：US09647439
申请日：2000-09-28
申请人： Theo Seiler , Michael Mrochen , Maik Kaemmerer
发明人： Theo Seiler , Michael Mrochen , Maik Kaemmerer
IPC分类号： A61B1820
CPC分类号： A61F9/008 , A61F9/00806 , A61F2009/00872 , A61F2009/0088
摘要： A device for photorefractive cornea surgery, in particular LASIK and PRK, of the eye for the correction of sight defects of a higher order provides for the following devices: an aberroscope (12, 14, 16, 22, 24, 28) for measuring the wave-front aberration of the entire optical system of the eye to be corrected in relation to a specific eye position, means (48) for deriving a photoablation profile from the measured wave-front aberration in such a way that a photoablation in accordance with the photoablation profile minimises the wave-front aberration, and a laser radiation source (30) and means (32, 38, 40, 48) for controlling the laser radiation in relation to the specific eye position in accordance with the photoablation profile.
摘要翻译：用于矫正高阶视力缺损的眼睛用于光折射角膜手术的装置，特别是LASIK和PRK，用于以下装置：用于测量所述眼睛的异常镜（12,14,16,22,24,28）相对于特定眼睛位置校正的眼睛的整个光学系统的波前像差，用于从所测量的波前像差导出光消融轮廓的装置（48），使得根据光消除轮廓最小化波前像差，以及激光辐射源（30）和用于根据光消除轮廓控制相对于特定眼睛位置的激光辐射的装置（32,38,40,48）。

5. 发明申请

US20080208177A1 Opthalmological Device 审中-公开
标题翻译：眼科装置
公开(公告)号：US20080208177A1
公开(公告)日：2008-08-28
申请号：US10588175
申请日：2005-02-03
申请人： Michael Mrochen , Theo Seiler
发明人： Michael Mrochen , Theo Seiler
IPC分类号： A61F9/01 , A61B18/20
CPC分类号： A61F9/009 , A61F9/0017 , A61F9/008 , A61F2009/00842 , A61F2009/00846 , A61F2009/00872 , A61N2005/0652 , A61N2005/0661
摘要： A device for correcting defective vision or corneal disease of an eye combines a device (16) for deforming the cornea of the eye and a device (18, 20) for hardening the cornea.
摘要翻译：用于矫正眼睛缺陷视力或角膜疾病的装置组合了用于使眼睛的角膜变形的装置（16）和用于硬化角膜的装置（18,20）。

6. 发明申请

US20110264082A1 APPARATUS FOR THE CROSS-LINKING OF OCULAR TISSUE WITH ELECTROMAGNETIC RADIATION 有权
标题翻译：用于电磁辐射的组织交叉连接的装置
公开(公告)号：US20110264082A1
公开(公告)日：2011-10-27
申请号：US13091755
申请日：2011-04-21
申请人： Michael Mrochen , Theo Seiler
发明人： Michael Mrochen , Theo Seiler
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61B18/203 , A61B2018/00452 , A61F9/0079 , A61F2009/00851 , A61F2009/00872 , A61N5/0616 , A61N5/062 , A61N2005/0661
摘要： An apparatus for generating an alteration of biomechanical properties of ocular tissue, into which a photosensitiser (14) has been introduced, contains means (18, 20) for radiating into the tissue electromagnetic radiation (12′) which reacts with the photosensitiser for the purpose of generating a cross-linking. The setting means permit an inhomogeneous distribution of the irradiance in the tissue and a setting of the depth of action (16′).
摘要翻译：一种用于产生已经引入光敏剂（14）的眼组织的生物力学性质改变的装置，包含用于辐射组织的电磁辐射（12'），所述电磁辐射（12'）与光敏剂反应以达到目的产生交联。设定装置允许组织中辐照度的不均匀分布和作用深度（16'）的设定。

7. 发明授权

US08936591B2 Apparatus for the cross-linking of ocular tissue with electromagnetic radiation 有权
标题翻译：用于用电磁辐射交联眼组织的装置
公开(公告)号：US08936591B2
公开(公告)日：2015-01-20
申请号：US13091755
申请日：2011-04-21
申请人： Michael Mrochen , Theo Seiler
发明人： Michael Mrochen , Theo Seiler
IPC分类号： A61B18/18 , A61N5/06 , A61F9/008 , A61B18/20 , A61B18/00 , A61F9/007
CPC分类号： A61F9/008 , A61B18/203 , A61B2018/00452 , A61F9/0079 , A61F2009/00851 , A61F2009/00872 , A61N5/0616 , A61N5/062 , A61N2005/0661
摘要： An apparatus for generating an alteration of biomechanical properties of ocular tissue, into which a photosensitizer (14) has been introduced, contains means (18, 20) for radiating into the tissue electromagnetic radiation (12′) which reacts with the photosensitizer for the purpose of generating a cross-linking. The setting means permit an inhomogeneous distribution of the irradiance in the tissue and a setting of the depth of action (16′).
摘要翻译：一种用于产生已经引入光敏剂（14）的眼组织的生物力学性质改变的装置包含用于辐射到与光敏剂反应的组织电磁辐射（12'）中的装置（18,20），用于该目的产生交联。设定装置允许组织中辐照度的不均匀分布和作用深度（16'）的设定。

8. 发明申请

US20150141971A1 MARKING LENTICULES FOR REFRACTIVE CORRECTION 审中-公开
标题翻译：用于折射校正的标记线
公开(公告)号：US20150141971A1
公开(公告)日：2015-05-21
申请号：US14401478
申请日：2012-06-07
申请人： Jörg Klenke , Katrin Skerl , Theo Seiler
发明人： Jörg Klenke , Katrin Skerl , Theo Seiler
IPC分类号： A61F9/008 , A61B19/00
CPC分类号： A61F9/00836 , A61B90/39 , A61B2090/3912 , A61B2090/3937 , A61B2090/3983 , A61F9/00827 , A61F2009/00844 , A61F2009/00872
摘要： In certain embodiments, marking a lenticule includes controlling a focus of pulsed laser radiation having ultrashort pulses. A lenticule marking is created in a cornea of an eye with the pulsed laser radiation to mark the lenticule. The lenticule is then created in the cornea with the pulsed laser radiation.
摘要翻译：在某些实施例中，标记微透镜包括控制具有超短脉冲的脉冲激光辐射的焦点。用脉冲激光辐射在眼睛的角膜中产生微透镜标记以标记微透镜。然后用脉冲激光辐射在角膜中产生微透镜。

9. 发明授权

US5461212A Astigmatic laser ablation of surfaces 失效
标题翻译：表面的散光激光烧蚀
公开(公告)号：US5461212A
公开(公告)日：1995-10-24
申请号：US72732
申请日：1993-06-04
申请人： Theo Seiler , Peter J. Klopotek
发明人： Theo Seiler , Peter J. Klopotek
IPC分类号： A61F9/008 , A61F9/01 , B23K26/073 , B23K26/40 , B23K26/06 , B23K26/02
CPC分类号： B23K26/073 , A61F9/00804 , A61F9/00817 , A61F2009/00872
摘要： Laser surface ablation methods and apparatus are disclosed reprofiling surfaces astigmatically. An optical system includes cylindrically-powered elements to form an elliptical laser irradiation pattern on a target surface. By successively altering the area of the elliptical irradiation, an astigmatic, bi-powered ablation profile is achieved. Preferably, the invention is used with an excimer laser for excimer laser keratoplasty, keratomileusis or other ablative eye surgeries.
摘要翻译：公开了激光表面消融方法和装置，使散射表面变得模糊。光学系统包括在目标表面上形成椭圆激光照射图案的圆柱形供能元件。通过依次改变椭圆辐射的面积，实现散光，双功率消融轮廓。优选地，本发明与准分子激光器用于准分子激光角膜移植术，角膜磨镶术或其它烧蚀性眼科手术一起使用。

10. 发明申请

US20130324984A1 DEVICE AND PROCESS FOR MACHINING THE CORNEA OF A HUMAN EYE WITH FOCUSED PULSED LASER RADIATION 有权
标题翻译：用聚焦脉冲激光辐射加工人眼的脊椎的装置和方法
公开(公告)号：US20130324984A1
公开(公告)日：2013-12-05
申请号：US13984392
申请日：2011-02-15
申请人： Theo Seiler , Mathias Woelfel , Christof Donitzky
发明人： Theo Seiler , Mathias Woelfel , Christof Donitzky
IPC分类号： A61F9/008
CPC分类号： A61F9/00836 , A61F2/147 , A61F9/00831 , A61F2009/00872
摘要： A device for machining the cornea of a human eye with focused pulsed laser radiation includes controllable components, a control computer for controlling these components and a control program for the control computer. The control program contains instructions that are designed to generate an incision figure in the cornea permitting the insertion of an intrastromal corneal ring implant. The incision figure includes a ring incision situated totally deep within the corneal tissue and an opening incision extending at right angles to the ring plane of the ring incision from the anterior surface of the cornea or from the posterior surface of the cornea as far as at least the ring incision. The ring incision exhibits, assigned to the opening incision (44), a radial—relative to the ring axis—widening zone in which the opening incision impinges on the ring incision.
摘要翻译：用聚焦脉冲激光辐射加工人眼角膜的装置包括可控组件，用于控制这些组件的控制计算机和用于控制计算机的控制程序。控制程序包含设计用于在角膜中产生切口图的指令，允许插入椎间孔内角膜环植入物。切口图包括位于角膜组织内完全深的环形切口和从角膜前表面或角膜后表面直角延伸到环形切口的环形平面的开口切口，至少至少环切口。所述环形切口在所述开口切口（44）中表现出相对于所述开口切口撞击所述环切口的所述环形轴线加宽区域的径向。

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