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1. 发明授权

US5461212A Astigmatic laser ablation of surfaces 失效
标题翻译：表面的散光激光烧蚀
公开(公告)号：US5461212A
公开(公告)日：1995-10-24
申请号：US72732
申请日：1993-06-04
申请人： Theo Seiler , Peter J. Klopotek
发明人： Theo Seiler , Peter J. Klopotek
IPC分类号： A61F9/008 , A61F9/01 , B23K26/073 , B23K26/40 , B23K26/06 , B23K26/02
CPC分类号： B23K26/073 , A61F9/00804 , A61F9/00817 , A61F2009/00872
摘要： Laser surface ablation methods and apparatus are disclosed reprofiling surfaces astigmatically. An optical system includes cylindrically-powered elements to form an elliptical laser irradiation pattern on a target surface. By successively altering the area of the elliptical irradiation, an astigmatic, bi-powered ablation profile is achieved. Preferably, the invention is used with an excimer laser for excimer laser keratoplasty, keratomileusis or other ablative eye surgeries.
摘要翻译：公开了激光表面消融方法和装置，使散射表面变得模糊。光学系统包括在目标表面上形成椭圆激光照射图案的圆柱形供能元件。通过依次改变椭圆辐射的面积，实现散光，双功率消融轮廓。优选地，本发明与准分子激光器用于准分子激光角膜移植术，角膜磨镶术或其它烧蚀性眼科手术一起使用。

2. 发明申请

US20080208177A1 Opthalmological Device 审中-公开
标题翻译：眼科装置
公开(公告)号：US20080208177A1
公开(公告)日：2008-08-28
申请号：US10588175
申请日：2005-02-03
申请人： Michael Mrochen , Theo Seiler
发明人： Michael Mrochen , Theo Seiler
IPC分类号： A61F9/01 , A61B18/20
CPC分类号： A61F9/009 , A61F9/0017 , A61F9/008 , A61F2009/00842 , A61F2009/00846 , A61F2009/00872 , A61N2005/0652 , A61N2005/0661
摘要： A device for correcting defective vision or corneal disease of an eye combines a device (16) for deforming the cornea of the eye and a device (18, 20) for hardening the cornea.
摘要翻译：用于矫正眼睛缺陷视力或角膜疾病的装置组合了用于使眼睛的角膜变形的装置（16）和用于硬化角膜的装置（18,20）。

3. 发明申请

US20150141971A1 MARKING LENTICULES FOR REFRACTIVE CORRECTION 审中-公开
标题翻译：用于折射校正的标记线
公开(公告)号：US20150141971A1
公开(公告)日：2015-05-21
申请号：US14401478
申请日：2012-06-07
申请人： Jörg Klenke , Katrin Skerl , Theo Seiler
发明人： Jörg Klenke , Katrin Skerl , Theo Seiler
IPC分类号： A61F9/008 , A61B19/00
CPC分类号： A61F9/00836 , A61B90/39 , A61B2090/3912 , A61B2090/3937 , A61B2090/3983 , A61F9/00827 , A61F2009/00844 , A61F2009/00872
摘要： In certain embodiments, marking a lenticule includes controlling a focus of pulsed laser radiation having ultrashort pulses. A lenticule marking is created in a cornea of an eye with the pulsed laser radiation to mark the lenticule. The lenticule is then created in the cornea with the pulsed laser radiation.
摘要翻译：在某些实施例中，标记微透镜包括控制具有超短脉冲的脉冲激光辐射的焦点。用脉冲激光辐射在眼睛的角膜中产生微透镜标记以标记微透镜。然后用脉冲激光辐射在角膜中产生微透镜。

4. 发明申请

US20130324984A1 DEVICE AND PROCESS FOR MACHINING THE CORNEA OF A HUMAN EYE WITH FOCUSED PULSED LASER RADIATION 有权
标题翻译：用聚焦脉冲激光辐射加工人眼的脊椎的装置和方法
公开(公告)号：US20130324984A1
公开(公告)日：2013-12-05
申请号：US13984392
申请日：2011-02-15
申请人： Theo Seiler , Mathias Woelfel , Christof Donitzky
发明人： Theo Seiler , Mathias Woelfel , Christof Donitzky
IPC分类号： A61F9/008
CPC分类号： A61F9/00836 , A61F2/147 , A61F9/00831 , A61F2009/00872
摘要： A device for machining the cornea of a human eye with focused pulsed laser radiation includes controllable components, a control computer for controlling these components and a control program for the control computer. The control program contains instructions that are designed to generate an incision figure in the cornea permitting the insertion of an intrastromal corneal ring implant. The incision figure includes a ring incision situated totally deep within the corneal tissue and an opening incision extending at right angles to the ring plane of the ring incision from the anterior surface of the cornea or from the posterior surface of the cornea as far as at least the ring incision. The ring incision exhibits, assigned to the opening incision (44), a radial—relative to the ring axis—widening zone in which the opening incision impinges on the ring incision.
摘要翻译：用聚焦脉冲激光辐射加工人眼角膜的装置包括可控组件，用于控制这些组件的控制计算机和用于控制计算机的控制程序。控制程序包含设计用于在角膜中产生切口图的指令，允许插入椎间孔内角膜环植入物。切口图包括位于角膜组织内完全深的环形切口和从角膜前表面或角膜后表面直角延伸到环形切口的环形平面的开口切口，至少至少环切口。所述环形切口在所述开口切口（44）中表现出相对于所述开口切口撞击所述环切口的所述环形轴线加宽区域的径向。

5. 发明申请

US20130281992A1 Extracting lenticules for refractive correction 审中-公开
$Extracting lenticules for refractive correction$
标题翻译：提取用于屈光矫正的微透镜
公开(公告)号：US20130281992A1
公开(公告)日：2013-10-24
申请号：US13454468
申请日：2012-04-24
申请人： Theo Seiler , Katrin Skerl , Jörg Klenke
发明人： Theo Seiler , Katrin Skerl , Jörg Klenke
IPC分类号： A61B18/20
CPC分类号： A61F9/00827 , A61F2009/00872 , A61F2009/00897
摘要： In certain embodiments, refractive correction includes controlling a focus of pulsed laser radiation having ultrashort pulses. A channel is created with the pulsed laser radiation to facilitate separation of the lenticule from the eye. A posterior incision is created with the pulsed laser radiation to form a posterior side of the lenticule. An anterior incision is created with the pulsed laser radiation to form an anterior side of the lenticule.
摘要翻译：在某些实施例中，屈光矫正包括控制具有超短脉冲的脉冲激光辐射的焦点。通过脉冲激光辐射创建通道，以便于将微透镜与眼睛分开。用脉冲激光辐射产生后切口以形成微透镜的后侧。用脉冲激光辐射产生前切口以形成微透镜的前侧。

6. 发明申请

US20110264082A1 APPARATUS FOR THE CROSS-LINKING OF OCULAR TISSUE WITH ELECTROMAGNETIC RADIATION 有权
标题翻译：用于电磁辐射的组织交叉连接的装置
公开(公告)号：US20110264082A1
公开(公告)日：2011-10-27
申请号：US13091755
申请日：2011-04-21
申请人： Michael Mrochen , Theo Seiler
发明人： Michael Mrochen , Theo Seiler
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61B18/203 , A61B2018/00452 , A61F9/0079 , A61F2009/00851 , A61F2009/00872 , A61N5/0616 , A61N5/062 , A61N2005/0661
摘要： An apparatus for generating an alteration of biomechanical properties of ocular tissue, into which a photosensitiser (14) has been introduced, contains means (18, 20) for radiating into the tissue electromagnetic radiation (12′) which reacts with the photosensitiser for the purpose of generating a cross-linking. The setting means permit an inhomogeneous distribution of the irradiance in the tissue and a setting of the depth of action (16′).
摘要翻译：一种用于产生已经引入光敏剂（14）的眼组织的生物力学性质改变的装置，包含用于辐射组织的电磁辐射（12'），所述电磁辐射（12'）与光敏剂反应以达到目的产生交联。设定装置允许组织中辐照度的不均匀分布和作用深度（16'）的设定。

7. 发明申请

US20090051876A1 Presbyopia Correction Program 有权
标题翻译：老花眼矫正计划
公开(公告)号：US20090051876A1
公开(公告)日：2009-02-26
申请号：US12063976
申请日：2006-08-09
申请人： Theo Seiler , Tobias Loreaz Florien Koller
发明人： Theo Seiler , Tobias Loreaz Florien Koller
IPC分类号： A61B3/11
CPC分类号： A61F9/008 , A61F9/00808 , A61F9/00812 , A61F2009/00846 , A61F2009/00872 , A61F2009/00895 , G02C7/027
摘要： A method of generating a computer program for control of an apparatus for photorefractive treatment of presbyopia by ablation of corneal tissue or a contact lens, comprising the following steps:(a) electing an eye model,(b) measuring the pupil diameter of the patient at far distance mesopically and at short distance photopically,(c) selecting wanted short and far distances regarding optimum sight,(d) calculating a global optimum regarding curvature (1/R) and asphericity (Q) of the cornea on the basis of the results obtained in steps (a) (b) and (c) by means of optical ray tracing and minimal spot diameter at the retina, and(e) deriving the computer program in accordance with the results of step (d).Alternatively step (d) includes determining a central steep island with a diameter in the range of 2 to 4 millimeters at the cornea and calculating a curvature and asphericity in the rest of the cornea.
摘要翻译：一种生成计算机程序的方法，用于通过消融角膜组织或隐形眼镜来控制用于光老化眼的光折射治疗装置，包括以下步骤：（a）选择眼模型，（b）测量患者的瞳孔直径（c）选择有关最佳视力的短距离和远距离，（d）根据角度计算角膜的曲率（1 / R）和非球面度（Q）的全局最优值在步骤（a）（b）和（c）中通过光线跟踪和视网膜处的最小斑点直径获得的结果，以及（e）根据步骤（d）的结果导出计算机程序。或者，步骤（d）包括在角膜处确定直径在2至4毫米范围内的中心陡峭岛，并计算其余角膜的曲率和非球面度。

8. 发明授权

US06887231B2 Control program for a device for photorefractive corneal surgery of the eye 有权
$Control program for a device for photorefractive corneal surgery of the eye$
标题翻译：用于眼睛光折射角膜手术的装置的控制程序
公开(公告)号：US06887231B2
公开(公告)日：2005-05-03
申请号：US10031107
申请日：2001-05-03
申请人： Michael Mrochen , Maik Kaemmerer , Theo Seiler
发明人： Michael Mrochen , Maik Kaemmerer , Theo Seiler
IPC分类号： A61F9/01 , A61F9/013 , A61B18/18
CPC分类号： A61F9/00806 , A61F9/00817 , A61F9/013 , A61F2009/00848 , A61F2009/00853 , A61F2009/00872 , A61F2009/00887
摘要： In a control program, according to which a laser-beam spot is guided, while being controlled with respect to position and time, over a cornea to be corrected photorefractively, so as to ablate a predetermined ablation profile therefrom, the effect of the angle between the laser earn and the corneal surface on the energy density of the laser-beam spot incident on the corneal surface and/or on the fraction of the laser-beam energy incident on the corneal surface which is reflected away, is taken into account when generating the control program.
摘要翻译：在控制程序中，根据该控制程序，激光束点在被相对于位置和时间被控制的同时被导光，通过光折射校正的角膜被引导，从而从其中消除预定的消融轮廓，入射到角膜表面上的激光束斑点的能量密度和/或入射到被反射的角膜表面上的激光束能量的分数上的激光获得和角膜表面在产生时被考虑控制程序。

9. 发明授权

US10238544B2 Marking lenticules for refractive correction 有权
$Marking lenticules for refractive correction$
公开(公告)号：US10238544B2
公开(公告)日：2019-03-26
申请号：US14401478
申请日：2012-06-07
申请人： Jörg Klenke , Katrin Skerl , Theo Seiler
发明人： Jörg Klenke , Katrin Skerl , Theo Seiler
IPC分类号： A61F9/008 , A61B90/00
摘要： In certain embodiments, marking a lenticule includes controlling a focus of pulsed laser radiation having ultrashort pulses. A lenticule marking is created in a cornea of an eye with the pulsed laser radiation to mark the lenticule. The lenticule is then created in the cornea with the pulsed laser radiation.

10. 发明授权

US10058453B2 Extracting lenticules for refractive correction 有权
$Extracting lenticules for refractive correction$
公开(公告)号：US10058453B2
公开(公告)日：2018-08-28
申请号：US13454468
申请日：2012-04-24
申请人： Theo Seiler , Katrin Skerl , Jörg Klenke
发明人： Theo Seiler , Katrin Skerl , Jörg Klenke
IPC分类号： A61B18/20 , A61F9/008
CPC分类号： A61F9/00827 , A61F2009/00872 , A61F2009/00897
摘要： In certain embodiments, refractive correction includes controlling a focus of pulsed laser radiation having ultrashort pulses. A channel is created with the pulsed laser radiation to facilitate separation of the lenticule from the eye. A posterior incision is created with the pulsed laser radiation to form a posterior side of the lenticule. An anterior incision is created with the pulsed laser radiation to form an anterior side of the lenticule.

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