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1. 发明授权

US08753321B2 Apparatus for coupling an element to the eye 有权
标题翻译：用于将元件耦合到眼睛的装置
公开(公告)号：US08753321B2
公开(公告)日：2014-06-17
申请号：US13435693
申请日：2012-03-30
申请人： Michael Mrochen , Michael Büeler , Christof Donitzky , Christian Wüllner
发明人： Michael Mrochen , Michael Büeler , Christof Donitzky , Christian Wüllner
IPC分类号： A61F9/009 , A61F9/008
CPC分类号： A61F9/009 , A61F9/008 , A61F9/013 , A61F2009/00857
摘要： The invention relates to methods of treating an eye that include coupling a suction ring to the eye and introducing a liquid into an interior chamber of a container element coupled to the suction ring. The container element is also coupled to a focusing lens of a laser system such that only the liquid within the interior chamber is positioned between the focusing lens of the laser system and an outer surface of the eye. In some embodiments, the suction ring has a first suction region that is designed to suck the suction ring onto an eye and a second suction region that is designed to couple the suction ring to the container element.
摘要翻译：本发明涉及治疗眼睛的方法，包括将吸入环连接到眼睛并将液体引入耦合到吸入环的容器元件的内部室中。容器元件还耦合到激光系统的聚焦透镜，使得仅内部腔室中的液体位于激光系统的聚焦透镜和眼睛的外表面之间。在一些实施例中，吸入环具有设计成将吸入环吸入眼睛的第一吸引区域和被设计成将吸入环连接到容器元件的第二吸入区域。

2. 发明授权

US08475433B2 Apparatus for coupling an element to the eye 有权
标题翻译：用于将元件耦合到眼睛的装置
公开(公告)号：US08475433B2
公开(公告)日：2013-07-02
申请号：US12531217
申请日：2008-03-13
申请人： Michael Mrochen , Michael Büeler , Christof Donitzky , Christian Wüllner
发明人： Michael Mrochen , Michael Büeler , Christof Donitzky , Christian Wüllner
IPC分类号： A61F9/007 , A61F9/013
CPC分类号： A61F9/009 , A61F9/008 , A61F9/013 , A61F2009/00857
摘要： The invention relates to a suction ring (2) for ophthalmic surgery, with a first suction region (4), which is designed to suck the suction ring onto an eye (18), and with a second suction region (10), which is designed to aspirate a functional element (12). The functional element and/or the suction ring may exhibit measuring means. The functional element may be formed in the manner of a container, so that it can receive a liquid which in operation is located between the cornea of the eye and a lens.
摘要翻译：本发明涉及一种用于眼科手术的吸入环（2），其具有第一吸入区域（4），其设计成将吸入环吸入眼睛（18），并且具有第二吸入区域（10）旨在抽吸功能元件（12）。功能元件和/或吸入环可以显示测量装置。功能元件可以以容器的形式形成，使得其可以接收在操作中位于眼睛的角膜和透镜之间的液体。

3. 发明授权

US08282629B2 Method for determining control information for photorefractive corneal surgery and method for providing correction information required therefor 有权
$Method for determining control information for photorefractive corneal surgery and method for providing correction information required therefor$
标题翻译：用于确定光折射角膜手术的控制信息的方法及其所需的校正信息的方法
公开(公告)号：US08282629B2
公开(公告)日：2012-10-09
申请号：US12063754
申请日：2006-08-18
申请人： Michael Mrochen , Michael Bueler
发明人： Michael Mrochen , Michael Bueler
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61F9/00804 , A61F2009/00848 , A61F2009/00872
摘要： A method for determining control information for controlling laser radiation irradiated onto the cornea of an eye to be treated photorefractively comprises correcting a corneal ablation profile, obtained by measuring optical properties of the eye, with the aid of correction information, the control information being formed on the basis of the corrected ablation profile thus produced. According to the invention, the correction of the ablation profile is performed in the spatial frequency domain. To this end, the ablation profile is transformed into a spatial frequency spectrum. Corrected amplitude or/and phase values are then determined for various discrete spectral components of the ablation profile on the basis of stored amplitude or/and phase correction information. Subsequently, the spatial frequency spectrum with the amplitude or/and phase corrected spectral components is backtransformed into the geometric spatial domain. The result is the corrected ablation profile. The amplitude and phase correction information in this case respectively represent for a number of spatial frequencies differing at least by the frequency value a predetermined relationship between values of the amplitude or/and phase at the relevant spatial frequency and corrected amplitude or/and phase values at this spatial frequency.
摘要翻译：一种用于确定用于控制照射到待处理的眼睛的角膜上的激光辐射的控制信息的方法，其特征在于，包括：通过校正信息校正通过测量眼睛的光学特性所获得的角膜消融轮廓，所述控制信息形成于由此产生的校正消融轮廓的基础。根据本发明，在空间频域中执行消融轮廓的校正。为此，将消融轮廓变换为空间频谱。然后基于存储的幅度或/和相位校正信息，确定消融轮廓的各种离散频谱分量的校正幅度或/和相位值。随后，具有振幅或/和相位校正的光谱分量的空间频谱被逆转换为几何空间域。结果是校正的消融轮廓。在这种情况下，幅度和相位校正信息分别表示对于空间频率的数量至少不同的频率值，相关空间频率处的振幅或/和相位的值之间的预定关系以及校正的幅度或/和相位值这个空间频率。

4. 发明授权

US09050173B2 Ophthalmologic surgical system 有权
标题翻译：眼科手术系统
公开(公告)号：US09050173B2
公开(公告)日：2015-06-09
申请号：US13162409
申请日：2011-06-16
申请人： Michael Mrochen , Olaf Kittelmann , Christof Donitzky , Rafael Zatonski
发明人： Michael Mrochen , Olaf Kittelmann , Christof Donitzky , Rafael Zatonski
IPC分类号： A61B18/20 , A61F9/008
CPC分类号： A61F9/008 , A61F9/00829 , A61F9/00836 , A61F2009/00859 , A61F2009/00872
摘要： The present invention relates to a method for generating a control program for ophthalmologic LASIK surgery, with which a pulsed laser system can be controlled for the photodisruptive cutting of a flap, having the following steps: obtaining empirical data, which relate to the effect in particular of flap shapes and ablation profiles on postoperative refractive results, obtaining measurement data relating to the eye to be treated, calculating an optimal cutting shape for the photodisruptive cutting of the flap by taking into account the said empirical data and the said measurement data, and generating the control program on the basis of the calculated cutting shape.
摘要翻译：本发明涉及一种用于产生眼科LASIK手术的控制程序的方法，通过该方法可以控制脉冲激光系统以进行光闸的切割，具有以下步骤：获得与特定效果有关的经验数据的瓣形和消融轮廓对术后屈光结果的影响，获得与待治疗的眼睛相关的测量数据，通过考虑所述经验数据和所述测量数据计算瓣膜的光破坏性切割的最佳切割形状，并产生基于计算出的切割形状的控制程序。

5. 发明申请

US20140009743A1 APPARATUS AND METHOD FOR OPTICAL COHERENCE TOMOGRAPHY 有权
标题翻译：光学相干图像的装置和方法
公开(公告)号：US20140009743A1
公开(公告)日：2014-01-09
申请号：US13984574
申请日：2011-02-15
申请人： Christof Donitzky , Klaus Vogler , Christian Wuellner , Claudia Gorschboth , Michael Mrochen
发明人： Christof Donitzky , Klaus Vogler , Christian Wuellner , Claudia Gorschboth , Michael Mrochen
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/1225 , A61B5/0066
摘要： There is provided an apparatus for recording a depth profile of a biological tissue, in particular a frontal eye section of a human eye, according to the principle of optical coherence tomography, comprising a light source adapted to generate a bundle of light rays, an interferometer arrangement having a beam splitter device adapted to spatially separate the bundle of light rays into a reference beam and a measurement beam directed toward the tissue, a reference beam deflection device adapted to deflect the reference beam, a beam superpositioning device adapted to spatially superimpose the deflected reference beam onto the measurement beam deflected by the tissue into a superpositioned beam, and a detector arrangement for detecting information in the superpositioned beam associated with the difference of the optical path length of the reference beam and the measurement beam.
摘要翻译：提供了一种用于根据光学相干断层摄影的原理记录生物组织的深度轮廓，特别是人眼的前眼部分的装置，其包括适于产生一束光线的光源，干涉仪具有分束器装置，其适于将光束空间分离成参考光束和朝向组织的测量光束，适于偏转参考光束的参考光束偏转装置，适于空间叠加被偏转的光束的光束叠加装置参考光束到由组织偏转到重叠光束的测量光束上，以及检测器装置，用于检测与参考光束和测量光束的光程长度的差异相关联的叠加光束中的信息。

6. 发明授权

US08475437B2 Radiation system for opthalmological applications 有权
标题翻译：用于眼科应用的辐射系统
公开(公告)号：US08475437B2
公开(公告)日：2013-07-02
申请号：US12307038
申请日：2007-06-28
申请人： Michael Mrochen , Michael Büeler , Urs Schelling
发明人： Michael Mrochen , Michael Büeler , Urs Schelling
IPC分类号： A61B18/18 , A61B3/10 , A61F9/008 , A61B3/12
CPC分类号： A61F9/008 , A61F9/00806 , A61F9/009 , A61F2009/00846 , A61F2009/00848 , A61F2009/00851 , A61F2009/00872 , A61F2009/0088
摘要： An irradiation system for opthalmological applications includes: a radiation source (1) for changing the biomechanical properties of the cornea; an optical system for directing the radiation towards the tissue; a beam-splitter (3) which couples out a part of the radiation directed towards the tissue for measuring or monitoring purposes; the beam-splitter also being set up in order to combine a further radiation of a different wavelength with the first-mentioned radiation; a controller for controlling the system, including a sensor; a mechanical stand (16) for supporting an irradiation unit (17); and interfaces for exchange of data.
摘要翻译：用于眼科应用的照射系统包括：用于改变角膜的生物力学性质的辐射源（1）; 用于将辐射引向组织的光学系统; 分束器（3），其耦合出朝向组织的一部分辐射，用于测量或监测目的; 分束器也被设置以便将不同波长的另外的辐射与首先提到的辐射组合; 用于控制系统的控制器，包括传感器; 用于支撑照射单元（17）的机械支架（16）; 和用于交换数据的接口。

7. 发明申请

US20080208177A1 Opthalmological Device 审中-公开
标题翻译：眼科装置
公开(公告)号：US20080208177A1
公开(公告)日：2008-08-28
申请号：US10588175
申请日：2005-02-03
申请人： Michael Mrochen , Theo Seiler
发明人： Michael Mrochen , Theo Seiler
IPC分类号： A61F9/01 , A61B18/20
CPC分类号： A61F9/009 , A61F9/0017 , A61F9/008 , A61F2009/00842 , A61F2009/00846 , A61F2009/00872 , A61N2005/0652 , A61N2005/0661
摘要： A device for correcting defective vision or corneal disease of an eye combines a device (16) for deforming the cornea of the eye and a device (18, 20) for hardening the cornea.
摘要翻译：用于矫正眼睛缺陷视力或角膜疾病的装置组合了用于使眼睛的角膜变形的装置（16）和用于硬化角膜的装置（18,20）。

8. 发明申请

US20120191077A1 APPARATUS FOR COUPLING AN ELEMENT TO THE EYE 有权
标题翻译：用于将元素耦合到眼睛的装置
公开(公告)号：US20120191077A1
公开(公告)日：2012-07-26
申请号：US13435693
申请日：2012-03-30
申请人： Michael MROCHEN , Michael BÜELER , Christof DONITZKY , Christian WÜLLNER
发明人： Michael MROCHEN , Michael BÜELER , Christof DONITZKY , Christian WÜLLNER
IPC分类号： A61B18/20
CPC分类号： A61F9/009 , A61F9/008 , A61F9/013 , A61F2009/00857
摘要： The invention relates to a suction ring (2) for ophthalmic surgery, with a first suction region (4), which is designed to suck the suction ring onto an eye (18), and with a second suction region (10), which is designed to aspirate a functional element (12). The functional element and/or the suction ring may exhibit measuring means. The functional element may be formed in the manner of a container, so that it can receive a liquid which in operation is located between the cornea of the eye and a lens.
摘要翻译：本发明涉及一种用于眼科手术的吸入环（2），其具有第一吸入区域（4），其设计成将吸入环吸入眼睛（18），并且具有第二吸入区域（10）旨在抽吸功能元件（12）。功能元件和/或吸入环可以显示测量装置。功能元件可以以容器的形式形成，使得其可以接收在操作中位于眼睛的角膜和透镜之间的液体。

9. 发明申请

US20110295244A1 Ophthalmologic Surgical System 有权
标题翻译：眼科手术系统
公开(公告)号：US20110295244A1
公开(公告)日：2011-12-01
申请号：US13162409
申请日：2011-06-16
申请人： Michael Mrochen , Olaf Kittelmann , Christof Donitzky , Rafael Zatonski
发明人： Michael Mrochen , Olaf Kittelmann , Christof Donitzky , Rafael Zatonski
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00829 , A61F9/00836 , A61F2009/00859 , A61F2009/00872
摘要： The present invention relates to a method for generating a control program for ophthalmologic LASIK surgery, with which a pulsed laser system can be controlled for the photodisruptive cutting of a flap, having the following steps: obtaining empirical data, which relate to the effect in particular of flap shapes and ablation profiles on postoperative refractive results, obtaining measurement data relating to the eye to be treated, calculating an optimal cutting shape for the photodisruptive cutting of the flap by taking into account the said empirical data and the said measurement data, and generating the control program on the basis of the calculated cutting shape.
摘要翻译：本发明涉及一种用于产生眼科LASIK手术的控制程序的方法，通过该方法可以控制脉冲激光系统以进行光闸的切割，具有以下步骤：获得与特定效果有关的经验数据的瓣形和消融轮廓对术后屈光结果的影响，获得与待治疗的眼睛相关的测量数据，通过考虑所述经验数据和所述测量数据计算瓣膜的光破坏性切割的最佳切割形状，并产生基于计算出的切割形状的控制程序。

10. 发明申请

US20110264082A1 APPARATUS FOR THE CROSS-LINKING OF OCULAR TISSUE WITH ELECTROMAGNETIC RADIATION 有权
标题翻译：用于电磁辐射的组织交叉连接的装置
公开(公告)号：US20110264082A1
公开(公告)日：2011-10-27
申请号：US13091755
申请日：2011-04-21
申请人： Michael Mrochen , Theo Seiler
发明人： Michael Mrochen , Theo Seiler
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61B18/203 , A61B2018/00452 , A61F9/0079 , A61F2009/00851 , A61F2009/00872 , A61N5/0616 , A61N5/062 , A61N2005/0661
摘要： An apparatus for generating an alteration of biomechanical properties of ocular tissue, into which a photosensitiser (14) has been introduced, contains means (18, 20) for radiating into the tissue electromagnetic radiation (12′) which reacts with the photosensitiser for the purpose of generating a cross-linking. The setting means permit an inhomogeneous distribution of the irradiance in the tissue and a setting of the depth of action (16′).
摘要翻译：一种用于产生已经引入光敏剂（14）的眼组织的生物力学性质改变的装置，包含用于辐射组织的电磁辐射（12'），所述电磁辐射（12'）与光敏剂反应以达到目的产生交联。设定装置允许组织中辐照度的不均匀分布和作用深度（16'）的设定。

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