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1. 发明授权

US09968484B2 Device and process for machining the cornea of a human eye with focused pulsed laser radiation 有权
公开(公告)号：US09968484B2
公开(公告)日：2018-05-15
申请号：US13984392
申请日：2011-02-15
申请人： Theo Seiler , Mathias Woelfel , Christof Donitzky
发明人： Theo Seiler , Mathias Woelfel , Christof Donitzky
IPC分类号： A61F9/008 , A61F2/14
CPC分类号： A61F9/00836 , A61F2/147 , A61F9/00831 , A61F2009/00872
摘要： A device for machining the cornea of a human eye with focused pulsed laser radiation includes controllable components, a control computer for controlling these components and a control program for the control computer. The control program contains instructions that are designed to generate an incision figure in the cornea permitting the insertion of an intrastromal corneal ring implant. The incision figure includes a ring incision situated totally deep within the corneal tissue and an opening incision extending at right angles to the ring plane of the ring incision from the anterior surface of the cornea or from the posterior surface of the cornea as far as at least the ring incision. The ring incision exhibits, assigned to the opening incision, a radial—relative to the ring axis—widening zone in which the opening incision impinges on the ring incision.

2. 发明申请

US20130324984A1 DEVICE AND PROCESS FOR MACHINING THE CORNEA OF A HUMAN EYE WITH FOCUSED PULSED LASER RADIATION 有权
标题翻译：用聚焦脉冲激光辐射加工人眼的脊椎的装置和方法
公开(公告)号：US20130324984A1
公开(公告)日：2013-12-05
申请号：US13984392
申请日：2011-02-15
申请人： Theo Seiler , Mathias Woelfel , Christof Donitzky
发明人： Theo Seiler , Mathias Woelfel , Christof Donitzky
IPC分类号： A61F9/008
CPC分类号： A61F9/00836 , A61F2/147 , A61F9/00831 , A61F2009/00872
摘要： A device for machining the cornea of a human eye with focused pulsed laser radiation includes controllable components, a control computer for controlling these components and a control program for the control computer. The control program contains instructions that are designed to generate an incision figure in the cornea permitting the insertion of an intrastromal corneal ring implant. The incision figure includes a ring incision situated totally deep within the corneal tissue and an opening incision extending at right angles to the ring plane of the ring incision from the anterior surface of the cornea or from the posterior surface of the cornea as far as at least the ring incision. The ring incision exhibits, assigned to the opening incision (44), a radial—relative to the ring axis—widening zone in which the opening incision impinges on the ring incision.
摘要翻译：用聚焦脉冲激光辐射加工人眼角膜的装置包括可控组件，用于控制这些组件的控制计算机和用于控制计算机的控制程序。控制程序包含设计用于在角膜中产生切口图的指令，允许插入椎间孔内角膜环植入物。切口图包括位于角膜组织内完全深的环形切口和从角膜前表面或角膜后表面直角延伸到环形切口的环形平面的开口切口，至少至少环切口。所述环形切口在所述开口切口（44）中表现出相对于所述开口切口撞击所述环切口的所述环形轴线加宽区域的径向。

3. 发明授权

US08425499B2 Apparatus for cutting a human cornea 有权
标题翻译：切割人角膜的装置
公开(公告)号：US08425499B2
公开(公告)日：2013-04-23
申请号：US12692301
申请日：2010-01-22
申请人： Christof Donitzky , Mathias Woelfel
发明人： Christof Donitzky , Mathias Woelfel
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00836 , A61F2009/00872 , A61F2009/00897
摘要： A device for machining the human cornea with focused pulsed femtosecond laser radiation comprises scanner components for local setting of the beam focus, a control computer for controlling the scanner components, and a control program for the control computer. The control program contains instructions that upon execution by the control computer are designed to bring about the generation of an incision figure in the cornea encompassing a flap incision (38, 40). In accordance with the invention the incision figure further encompasses an auxiliary incision (50) connected with the flap incision and leading locally, preferentially directly, away from the latter as far as the surface of the cornea. The auxiliary incision is expediently generated temporally ahead of the flap incision and forms a discharge channel through which gases can escape that may arise in the course of the cutting of the flap incision.
摘要翻译：用于用聚焦脉冲飞秒激光辐射加工人角膜的装置包括用于局部设置束聚焦的扫描器部件，用于控制扫描器部件的控制计算机以及用于控制计算机的控制程序。控制程序包含指令，在由控制计算机执行时被设计成在包括瓣切口（38,40）的角膜中产生切口图形。根据本发明，切口图还包括与瓣切口连接的辅助切口（50），其局部地，优先地直接远离角膜的表面。辅助切口在时间上有利地在瓣切口之前产生，并形成排出通道，通过该排出通道，气体可以在切割切口的过程中出现。

4. 发明申请

US20110184394A1 Apparatus for Cutting a Human Cornea 有权
标题翻译：切割人角膜的装置
公开(公告)号：US20110184394A1
公开(公告)日：2011-07-28
申请号：US12692301
申请日：2010-01-22
申请人： Christof Donitzky , Mathias Woelfel
发明人： Christof Donitzky , Mathias Woelfel
IPC分类号： A61F9/009 , A61B18/20 , A61F9/008
CPC分类号： A61F9/008 , A61F9/00836 , A61F2009/00872 , A61F2009/00897
摘要： A device for machining the human cornea with focused pulsed femtosecond laser radiation comprises scanner components for local setting of the beam focus, a control computer for controlling the scanner components, and a control program for the control computer. The control program contains instructions that upon execution by the control computer are designed to bring about the generation of an incision figure in the cornea encompassing a flap incision (38, 40). In accordance with the invention the incision figure further encompasses an auxiliary incision (50) connected with the flap incision and leading locally, preferentially directly, away from the latter as far as the surface of the cornea. The auxiliary incision is expediently generated temporally ahead of the flap incision and forms a discharge channel through which gases can escape that may arise in the course of the cutting of the flap incision.
摘要翻译：用于用聚焦脉冲飞秒激光辐射加工人角膜的装置包括用于局部设置束聚焦的扫描器部件，用于控制扫描器部件的控制计算机以及用于控制计算机的控制程序。控制程序包含指令，在由控制计算机执行时被设计成在包括瓣切口（38,40）的角膜中产生切口图形。根据本发明，切口图还包括与瓣切口连接的辅助切口（50），其局部地，优先地直接远离角膜的表面。辅助切口在时间上有利地在瓣切口之前产生，并形成排出通道，通过该排出通道，气体可以在切割切口的过程中出现。

5. 发明授权

US09050173B2 Ophthalmologic surgical system 有权
标题翻译：眼科手术系统
公开(公告)号：US09050173B2
公开(公告)日：2015-06-09
申请号：US13162409
申请日：2011-06-16
申请人： Michael Mrochen , Olaf Kittelmann , Christof Donitzky , Rafael Zatonski
发明人： Michael Mrochen , Olaf Kittelmann , Christof Donitzky , Rafael Zatonski
IPC分类号： A61B18/20 , A61F9/008
CPC分类号： A61F9/008 , A61F9/00829 , A61F9/00836 , A61F2009/00859 , A61F2009/00872
摘要： The present invention relates to a method for generating a control program for ophthalmologic LASIK surgery, with which a pulsed laser system can be controlled for the photodisruptive cutting of a flap, having the following steps: obtaining empirical data, which relate to the effect in particular of flap shapes and ablation profiles on postoperative refractive results, obtaining measurement data relating to the eye to be treated, calculating an optimal cutting shape for the photodisruptive cutting of the flap by taking into account the said empirical data and the said measurement data, and generating the control program on the basis of the calculated cutting shape.
摘要翻译：本发明涉及一种用于产生眼科LASIK手术的控制程序的方法，通过该方法可以控制脉冲激光系统以进行光闸的切割，具有以下步骤：获得与特定效果有关的经验数据的瓣形和消融轮廓对术后屈光结果的影响，获得与待治疗的眼睛相关的测量数据，通过考虑所述经验数据和所述测量数据计算瓣膜的光破坏性切割的最佳切割形状，并产生基于计算出的切割形状的控制程序。

6. 发明申请

US20140364840A1 DEVICE AND PROCESS FOR SURGERY ON THE HUMAN EYE 有权
标题翻译：人类手术手术和手术
公开(公告)号：US20140364840A1
公开(公告)日：2014-12-11
申请号：US14345378
申请日：2011-10-10
申请人： Christof Donitzky , Klaus Vogler
发明人： Christof Donitzky , Klaus Vogler
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00827 , A61F2009/00872 , A61F2009/00897
摘要： A laser apparatus is controlled by a control program that operates to use laser radiation to generate an incision figure in the cornea of an eye, the incision figure including a an incision that bounds a corneal tissue volume. The control program operates to move the radiation focus in a radiation propogation direction successively in a plurality of superposed planes such that the radiation focus is moved without motion control in the propogation direction. The control program provides, for each plane, for a meandering scan path of the radiation focus that extends outside the tissue volume. The control program operates to allow through to the eye, in each plane, at least such radiation pulses that generate the first incision and to blank, in at least a fraction of the planes, at least a fraction of radiation pulses assigned to regions of the path that are at a distance from the incision.
摘要翻译：激光设备由控制程序控制，该控制程序操作以使用激光辐射来在眼睛的角膜中产生切口图，切口图包括限定角膜组织体积的切口。控制程序用于在多个叠加平面中连续移动辐射传播方向上的辐射聚焦，使得辐射聚焦在传播方向上移动而不进行运动控制。控制程序为每个平面提供延伸到组织体积之外的辐射聚焦的曲折扫描路径。控制程序的作用是允许至少在每个平面中的眼睛产生这样的辐射脉冲，该辐射脉冲在至少一部分平面中产生第一切口并且空白至少一部分分配给距离切口一定距离的路径。

7. 发明申请

US20140228825A1 SYSTEM, INTERFACE DEVICES, USE OF THE INTERFACE DEVICES AND METHOD FOR EYE SURGERY 审中-公开
标题翻译：系统，接口装置，接口装置的使用和眼科手术的方法
公开(公告)号：US20140228825A1
公开(公告)日：2014-08-14
申请号：US14345908
申请日：2011-10-10
申请人： Claudia Gorschboth , Klaus Vogler , Christof Donitzky
发明人： Claudia Gorschboth , Klaus Vogler , Christof Donitzky
IPC分类号： A61F9/008 , A61F9/009
摘要： A laser system for eye surgery comprises an eye-surgical laser apparatus and a set of interface devices. The eye-surgical laser apparatus has optical components for providing pulsed focused laser radiation with radiation properties matched to the generation of photodisruptions in human eye tissue and a control unit for positional control of the radiation focus of the laser radiation. The control unit is designed for executing various control programs that represent various types of incision figures. Each interface device includes a contact body that is transparent to the laser radiation, with an abutment face for abutment against an eye to be treated, and a coupling portion for detachable coupling of the interface device onto a counter-coupling portion of the laser apparatus. The interface devices differ by virtue of a differing optical effect on the laser radiation provided in the laser apparatus.
摘要翻译：用于眼科手术的激光系统包括眼外科激光装置和一组界面装置。眼外科激光装置具有用于提供脉冲聚焦激光辐射的光学部件，其具有与人眼组织中的光致中断的产生匹配的辐射特性和用于位置控制激光辐射的辐射焦点的控制单元。控制单元被设计用于执行表示各种类型切口图形的各种控制程序。每个接口装置包括对激光辐射透明的接触体，具有用于邻接待处理的眼睛的邻接面，以及用于将接口装置可拆卸地联接到激光装置的反向耦合部分上的耦合部分。接口装置由于对激光装置中提供的激光辐射的不同光学效应而不同。

8. 发明授权

US08728061B2 Laser system that is gentle on the eyes, for refractive surgery 有权
$Laser system that is gentle on the eyes, for refractive surgery$
标题翻译：激光系统是温和的眼睛，用于屈光手术
公开(公告)号：US08728061B2
公开(公告)日：2014-05-20
申请号：US12532058
申请日：2008-03-19
申请人： Christof Donitzky
发明人： Christof Donitzky
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00825 , A61F2009/00872
摘要： Described is an eye treatment device having a radiation source, the light emitted by the radiation source having such a wavelength range that it brings about a reaction in a treatment region of an eye and is absorbed, at least partially, in at least one of the regions located behind same in the direction of the retina that are in front of the retina. The light emitted by the radiation source can have a wavelength range in which the treatment region is partially transmissive. The treatment region can be the cornea. The reaction brought about in the treatment region by the light can be an ablation of tissue. The reaction brought about in the treatment region by the light can also be a laser-induced optical perforation of tissue, which is also referred to as photo-disruption. The radiation source can be a laser source. The wavelength range of the light emitted by the radiation source is approximately 1600 nm to approximately 1700 nm, preferably approximately 1625 nm to approximately 1675 nm, most preferably approximately 1640 nm to approximately 1660 nm.
摘要翻译：描述了具有辐射源的眼睛治疗装置，由辐射源发射的光具有这样的波长范围，使得其在眼睛的治疗区域中产生反应并至少部分地被吸收在至少一个位于视网膜前方的视网膜方向相同的区域。由辐射源发射的光可以具有处理区域部分透射的波长范围。治疗区域可以是角膜。通过光在治疗区域产生的反应可以是组织的消融。在光处理区域产生的反应也可以是激光诱导的组织光学穿孔，这也被称为光破坏。辐射源可以是激光源。由辐射源发射的光的波长范围为约1600nm至约1700nm，优选约1625nm至约1675nm，最优选约1640nm至约1660nm。

9. 发明申请

US20140009743A1 APPARATUS AND METHOD FOR OPTICAL COHERENCE TOMOGRAPHY 有权
标题翻译：光学相干图像的装置和方法
公开(公告)号：US20140009743A1
公开(公告)日：2014-01-09
申请号：US13984574
申请日：2011-02-15
申请人： Christof Donitzky , Klaus Vogler , Christian Wuellner , Claudia Gorschboth , Michael Mrochen
发明人： Christof Donitzky , Klaus Vogler , Christian Wuellner , Claudia Gorschboth , Michael Mrochen
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/1225 , A61B5/0066
摘要： There is provided an apparatus for recording a depth profile of a biological tissue, in particular a frontal eye section of a human eye, according to the principle of optical coherence tomography, comprising a light source adapted to generate a bundle of light rays, an interferometer arrangement having a beam splitter device adapted to spatially separate the bundle of light rays into a reference beam and a measurement beam directed toward the tissue, a reference beam deflection device adapted to deflect the reference beam, a beam superpositioning device adapted to spatially superimpose the deflected reference beam onto the measurement beam deflected by the tissue into a superpositioned beam, and a detector arrangement for detecting information in the superpositioned beam associated with the difference of the optical path length of the reference beam and the measurement beam.
摘要翻译：提供了一种用于根据光学相干断层摄影的原理记录生物组织的深度轮廓，特别是人眼的前眼部分的装置，其包括适于产生一束光线的光源，干涉仪具有分束器装置，其适于将光束空间分离成参考光束和朝向组织的测量光束，适于偏转参考光束的参考光束偏转装置，适于空间叠加被偏转的光束的光束叠加装置参考光束到由组织偏转到重叠光束的测量光束上，以及检测器装置，用于检测与参考光束和测量光束的光程长度的差异相关联的叠加光束中的信息。

10. 发明申请

US20130274723A1 DEVICE AND PROCESS FOR MACHINING THE HUMAN EYE USING LASER TECHNOLOGY 有权
标题翻译：使用激光技术加工人眼的设备和方法
公开(公告)号：US20130274723A1
公开(公告)日：2013-10-17
申请号：US13865487
申请日：2013-04-18
申请人： Christof Donitzky , Jörg Klenke , Christian Wüllner
发明人： Christof Donitzky , Jörg Klenke , Christian Wüllner
IPC分类号： A61F9/008
CPC分类号： A61F9/00806 , A61F9/00804 , A61F9/00836 , A61F9/009 , A61F2009/00872 , A61F2009/00897
摘要： A device for machining the human cornea with focused laser radiation includes controllable components for setting the location of the radiation focus, a control computer for controlling these components, and also a control program for the control computer. The control program contains instructions that have been designed to bring about, upon execution by the control computer, the generation of incisions in the cornea in accordance with a predetermined incision figure, the incision figure defining a corneal bed, a flap situated on the bed and also at least one tissue strip situated in the region of the peripheral edge of the flap between the bed and the flap and extending along the edge of the flap. After the flap has been folded away, the tissue strip has to be removed and enables a creaseless post-ablative close fitting of the folded-back flap against the surface of the bed. In this manner, microstriae which may impair the visual capacity can be avoided.
摘要翻译：用于用聚焦激光辐射加工人角膜的装置包括用于设置辐射聚焦位置的可控组件，用于控制这些部件的控制计算机，以及用于控制计算机的控制程序。控制程序包含指令，其被设计为在控制计算机执行时根据预定切口图形形成角膜切割，限定角膜床的切口图形，位于床上的皮瓣和还有至少一个组织条，位于床和翼片之间的翼片的周边边缘的区域中并且沿翼片的边缘延伸。在折叠折叠之后，必须去除组织带，并且使得折叠式折叠板的无残余的消融后紧密配合在床的表面上。以这种方式，可以避免可能损害视觉容量的微阵。

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