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1. 发明授权

US5871443A Cardiac mapping and ablation systems 失效
公开(公告)号：US5871443A
公开(公告)日：1999-02-16
申请号：US747811
申请日：1996-11-14
申请人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
发明人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61B5/04
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.

2. 发明授权

US6052607A Cardiac mapping and ablation systems 失效
标题翻译：心脏图和消融系统
公开(公告)号：US6052607A
公开(公告)日：2000-04-18
申请号：US34553
申请日：1998-03-03
申请人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
发明人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61B5/0408
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.
摘要翻译：用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。每个花键的主体由多个交替导电层和非导电层形成。提供单独的导电路径以将每个电极连接到不同的一个导电层。每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。

3. 发明授权

US5509419A Cardiac mapping and ablation systems 失效
标题翻译：心脏图和消融系统
公开(公告)号：US5509419A
公开(公告)日：1996-04-23
申请号：US168476
申请日：1993-12-16
申请人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
发明人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61N5/02
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can he processed.
摘要翻译：用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。每个花键的主体由多个交替导电层和非导电层形成。提供单独的导电路径以将每个电极连接到不同的一个导电层。每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。

4. 发明授权

US6163716A Cardiac mapping and ablation systems 失效
标题翻译：心脏图和消融系统
公开(公告)号：US6163716A
公开(公告)日：2000-12-19
申请号：US433604
申请日：1999-11-02
申请人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
发明人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61B5/0402
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , Y10T29/49002 , Y10T29/49117 , C08L1/02
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connnected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.
摘要翻译：用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。每个花键的主体由多个交替导电层和非导电层形成。提供单独的导电路径以将每个电极连接到不同的一个导电层。每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。

5. 发明授权

US5549108A Cardiac mapping and ablation systems 失效
标题翻译：心脏图和消融系统
公开(公告)号：US5549108A
公开(公告)日：1996-08-27
申请号：US252060
申请日：1994-06-01
申请人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
发明人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
IPC分类号： A61B5/042 , A61N1/06 , A61B5/0402 , A61N1/05
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61N1/06 , A61B2562/0209 , A61B2562/043
摘要： A cardiac diagnosis and treatment system comprises a support carrying at least two electrodes. A conductor is associated with the support for selectively directing electrical signals to and from each electrode. The conductor includes a first buss for delivering power from an external power source, a second buss for transmitting electrode signals to an external signal processor, and a third buss for receiving control signals from an external signal source to multiplex the electrode signals from the electrodes through the second buss. A conduction line conducts power, control signals, and electrode signals from the external sources to the conductor.
摘要翻译：心脏诊断和治疗系统包括承载至少两个电极的支撑件。导体与用于选择性地将电信号导向每个电极和从每个电极引导的支撑件相关联。导体包括用于从外部电源传递电力的第一总线，用于将电极信号传输到外部信号处理器的第二总线，以及用于从外部信号源接收控制信号的第三总线，以将来自电极的电极信号多路复用第二个总线导线将电源，控制信号和电极信号从外部源传导到导体。

6. 发明授权

US5309910A Cardiac mapping and ablation systems 失效
标题翻译：心脏图和消融系统
公开(公告)号：US5309910A
公开(公告)日：1994-05-10
申请号：US951157
申请日：1992-09-25
申请人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
发明人： Stuart D. Edwards , Thomas F. Kordis , David K. Swanson
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.
摘要翻译：用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。每个花键的主体由多个交替导电层和非导电层形成。提供单独的导电路径以将每个电极连接到不同的一个导电层。每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。

7. 发明授权

US06716196B2 Catheter system for delivery of Therapeutic compounds to cardiac tissue 失效
标题翻译：将治疗性化合物递送至心脏组织的导管系统
公开(公告)号：US06716196B2
公开(公告)日：2004-04-06
申请号：US09797483
申请日：2001-02-28
申请人： Michael D. Lesh , Thomas F. Kordis , Stuart D. Edwards
发明人： Michael D. Lesh , Thomas F. Kordis , Stuart D. Edwards
IPC分类号： A61M5178
CPC分类号： A61M25/0136 , A61B17/22 , A61B2017/00243 , A61B2017/22082 , A61B2017/3488 , A61B2018/00273 , A61B2018/00815 , A61B2018/1425 , A61B2018/1435 , A61B2090/3784 , A61M25/0084 , A61M25/0133 , A61M25/0147 , A61N7/02
摘要： This is a method and an apparatus for the introduction of therapeutic compounds into tissue, particularly cardiac tissue. The apparatus includes a catheter having an elongated flexible body and a tissue infusion apparatus including a hollow infusion needle configured to secure the needle into the tissue when the needle is at least partially inserted into the tissue to help prevent inadvertent removal of the needle from the tissue. This permits the selected therapeutic compound to be delivered to a specific site. The catheter may also include a visualization assembly including a transducer at the distal end of the body.
摘要翻译：这是用于将治疗化合物引入组织，特别是心脏组织的方法和装置。所述装置包括具有细长柔性体的导管和包括中空输液针的组织浸液装置，所述中空灌注针构造成当针至少部分插入组织中时将针固定到组织中，以帮助防止针头从组织中无意中移除。这允许将所选择的治疗化合物递送到特定部位。导管还可以包括可视化组件，其包括在身体的远端处的换能器。

8. 发明授权

US5471982A Cardiac mapping and ablation systems 失效
标题翻译：心脏图和消融系统
公开(公告)号：US5471982A
公开(公告)日：1995-12-05
申请号：US951728
申请日：1992-09-29
申请人： Stuart D. Edwards , Jerome Jackson , Ingemar H. Lundquist , Thomas F. Kordis , Alan L. Kaganov
发明人： Stuart D. Edwards , Jerome Jackson , Ingemar H. Lundquist , Thomas F. Kordis , Alan L. Kaganov
IPC分类号： A61B5/042 , A61B18/14 , A61N1/06 , A61B5/0402
CPC分类号： A61B5/6856 , A61B18/1492 , A61B5/0422 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61N1/06 , A61B2017/22038 , A61B2018/00083 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00357 , A61B2018/00839 , A61B2018/1861 , A61B2562/0209 , A61B2562/043
摘要： An improved probe for cardiac diagnosis and/or treatment includes a control handle and a catheter for insertion into the heart. The catheter has a distal end, a proximal end and at least one lumen connecting said distal and proximal ends. It also includes a flexible inner tube and an outer sheath enveloping said tube. At least one measuring electrode or ablation device is attached to the distal end of the tube. The outer sheath and the inner tube are rotatable relative to each other so that the electrode or device can be rotated within the heart without rotating the outer sheath. The sheath is also axially movable relative to the tube to selectively enclose or expose the electrode or device for use.
摘要翻译：用于心脏诊断和/或治疗的改进探针包括控制手柄和用于插入心脏的导管。导管具有远端，近端和连接所述远端和近端的至少一个腔。它还包括柔性内管和包封所述管的外护套。至少一个测量电极或消融装置附接到管的远端。外鞘和内管可相对于彼此旋转，使得电极或装置可以在心脏内旋转而不旋转外护套。鞘也可以相对于管轴向移动，以选择性地包围或暴露电极或装置以供使用。

9. 发明授权

US07413568B2 Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like 失效
标题翻译：用于在治疗心脏病况等中烧蚀组织以形成复杂病变图案的复合结构和方法
公开(公告)号：US07413568B2
公开(公告)日：2008-08-19
申请号：US09870288
申请日：2001-05-29
申请人： David K. Swanson , Sidney D. Fleischman , Thomas F. Kordis , David L. McGee
发明人： David K. Swanson , Sidney D. Fleischman , Thomas F. Kordis , David L. McGee
IPC分类号： A61B18/18 , A61N1/00
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2018/00083 , A61B2018/00196 , A61B2018/00214 , A61B2018/00267 , A61B2018/00577 , A61B2018/00839 , A61B2018/1437 , A61B2018/1467 , A61B2018/1497
摘要： A method of ablating tissue in the heart to treat atrial fibrillation introduces into a selected atrium an energy emitting element. The method exposes the element to a region of the atrial wall and applies ablating energy to the element to thermally destroy tissue. The method forms a convoluted lesion pattern comprising elongated straight lesions and elongated curvilinear lesions. The lesion pattern directs electrical impulses within the atrial myocardium along a path that activates the atrial myocardium while interrupting reentry circuits that, if not interrupted, would cause fibrillation. The method emulates the surgical maze procedure, but lends itself to catheter-based procedures that do not require open heart surgical techniques. A composite structure for performing the method is formed using a template that displays in planar view a desired lesion pattern for the tissue. An array of spaced apart element is laid on the template. Guided by the template, energy emitting and non-energy emitting zones are formed on the elements. By overlaying the elements, the composite structure is formed, which can be introduced into the body to ablate tissue using catheter-based, vascular access techniques.
摘要翻译：心脏中消融组织以治疗心房颤动的方法将所选择的心房引入能量发射元件。该方法将该元件暴露于心房壁的一个区域，并向该元件施加消融能量以热破坏组织。该方法形成包括细长的直线损伤和细长的曲线损伤的褶皱病变图案。病变图案沿着激活心房心肌的路径引导心房心肌内的电脉冲，同时中断再入电路，如果不中断，将引起原纤维化。该方法模拟外科迷宫手术，但适用于不需要开放心脏手术技术的基于导管的手术。用于执行该方法的复合结构使用在平面图中显示用于组织的期望损伤图案的模板来形成。间隔开的元件阵列放置在模板上。在模板的指导下，在元件上形成能量发射和非能量发射区。通过覆盖元件，形成复合结构，其可以引入体内以使用基于导管的血管通路技术来烧蚀组织。

10. 发明授权

US06736811B2 Expandable-collapsible electrode structures made of electrically conductive material 有权
标题翻译：由导电材料制成的可膨胀 - 可折叠电极结构
公开(公告)号：US06736811B2
公开(公告)日：2004-05-18
申请号：US10170988
申请日：2002-06-11
申请人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
发明人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
IPC分类号： A61B1814
CPC分类号： A61N1/06 , A61B18/1492 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839 , A61B2018/1253 , A61B2018/1472 , A61B2218/002 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , C08L1/02
摘要： Electrode assemblies and associated systems employ a nonporous wall having an exterior for contacting tissue. The exterior peripherally surrounds an interior area. The wall is essentially free of electrically conductive material. The wall is adapted to assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. The assemblies and systems include a lumen that conveys a medium containing ions into the interior area. An element free of physical contact with the wall couples the medium within the interior area to a source of electrical energy to enable ionic transport of electrical energy from the source through the medium to the wall for capacitive coupling to tissue contacting the exterior of the wall.
摘要翻译：电极组件和相关系统采用具有用于接触组织的外部的无孔壁。外部外围围绕着内部区域。该壁基本上不含导电材料。壁适于呈现具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的扩展几何形状。组件和系统包括将含有离子的介质输送到内部区域的内腔。与壁物理接触的元件将内部区域内的介质耦合到电能源，以使电能从源通过介质到壁的电能离子传输，用于电容耦合到与壁的外部接触的组织。

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