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1. 发明授权

US06736811B2 Expandable-collapsible electrode structures made of electrically conductive material 有权
标题翻译：由导电材料制成的可膨胀 - 可折叠电极结构
公开(公告)号：US06736811B2
公开(公告)日：2004-05-18
申请号：US10170988
申请日：2002-06-11
申请人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
发明人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
IPC分类号： A61B1814
CPC分类号： A61N1/06 , A61B18/1492 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839 , A61B2018/1253 , A61B2018/1472 , A61B2218/002 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , C08L1/02
摘要： Electrode assemblies and associated systems employ a nonporous wall having an exterior for contacting tissue. The exterior peripherally surrounds an interior area. The wall is essentially free of electrically conductive material. The wall is adapted to assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. The assemblies and systems include a lumen that conveys a medium containing ions into the interior area. An element free of physical contact with the wall couples the medium within the interior area to a source of electrical energy to enable ionic transport of electrical energy from the source through the medium to the wall for capacitive coupling to tissue contacting the exterior of the wall.
摘要翻译：电极组件和相关系统采用具有用于接触组织的外部的无孔壁。外部外围围绕着内部区域。该壁基本上不含导电材料。壁适于呈现具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的扩展几何形状。组件和系统包括将含有离子的介质输送到内部区域的内腔。与壁物理接触的元件将内部区域内的介质耦合到电能源，以使电能从源通过介质到壁的电能离子传输，用于电容耦合到与壁的外部接触的组织。

2. 发明授权

US5968040A Systems and methods using asymmetric multiple electrode arrays 失效
标题翻译：使用不对称多电极阵列的系统和方法
公开(公告)号：US5968040A
公开(公告)日：1999-10-19
申请号：US728698
申请日：1996-10-28
申请人： David K. Swanson , Sidney D. Fleischman , Dorin Panescu , James G. Whayne , Thomas F. Kordis
发明人： David K. Swanson , Sidney D. Fleischman , Dorin Panescu , James G. Whayne , Thomas F. Kordis
IPC分类号： A61N1/00 , A61B17/39
CPC分类号： A61N1/00
摘要： Systems and methods support arrays of multiple electrodes in asymmetric pattern, either radially, or axially, or both. Radial asymmetry makes it possible provide localized density of electrodes. Axial asymmetry makes it possible to locate electrodes in a pattern that closely conforms to the irregular contours of an interior body cavity, like the heart. In a preferred embodiment, the systems and methods operate the multiple electrode arrays to form continuous lesion patterns.
摘要翻译：系统和方法以径向或轴向或两者不对称的方式支持多个电极的阵列。径向不对称使得可能提供电极的局部密度。轴向不对称使得可以将电极定位成与内部体腔的不规则轮廓紧密一致的图案，如心脏。在优选实施例中，系统和方法操作多个电极阵列以形成连续的病变图案。

3. 发明授权

US06179835B2 Expandable-collapsible electrode structures made of electrically conductive material 失效
标题翻译：由导电材料制成的可膨胀 - 可折叠电极结构
公开(公告)号：US06179835B2
公开(公告)日：2001-01-30
申请号：US09300936
申请日：1999-04-27
申请人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
发明人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
IPC分类号： A61B1814
CPC分类号： A61N1/06 , A61B18/1492 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839 , A61B2018/1253 , A61B2018/1472 , A61B2218/002 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , C08L1/02
摘要： Electrode assemblies and associated systems employ a nonporous wall having an exterior for contacting tissue. The exterior peripherally surrounds an interior area. The wall is essentially free of electrically conductive material. The wall is adapted to assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. The assemblies and systems include a lumen that conveys a medium containing ions into the interior area. An element free of physical contact with the wall couples the medium within the interior area to a source of electrical energy to enable ionic transport of electrical energy from the source through the medium to the wall for capacitive coupling to tissue contacting the exterior of the wall.
摘要翻译：电极组件和相关系统采用具有用于接触组织的外部的无孔壁。外部外围围绕着内部区域。该壁基本上不含导电材料。壁适于呈现具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的扩展几何形状。组件和系统包括将含有离子的介质输送到内部区域的内腔。与壁物理接触的元件将内部区域内的介质耦合到电能源，以使电能从源通过介质到壁的电能离子传输，用于电容耦合到与壁的外部接触的组织。

4. 发明授权

US6014590A Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions 失效
标题翻译：使用具有不对称机械性能的结构以支持与内部身体区域中的组织接触的诊断或治疗元件的系统和方法
公开(公告)号：US6014590A
公开(公告)日：2000-01-11
申请号：US742564
申请日：1996-10-28
申请人： James G. Whayne , Sidney D. Fleischman , Dorin Panescu , Thomas F. Kordis , David K. Swanson
发明人： James G. Whayne , Sidney D. Fleischman , Dorin Panescu , Thomas F. Kordis , David K. Swanson
IPC分类号： A61B17/39
摘要： Structures having asymmetric mechanical properties provide enhanced ability to support therapeutic or diagnostic elements in contact with tissue in an interior body region. The support structure includes a first region, which exhibits a first mechanical property affecting tissue contact, and a second region spaced from the first region about the axis, which exhibits a second mechanical property, different than the first mechanical property, affecting tissue contact. In a preferred embodiment, the first and second mechanical properties correlate with stiffness of the respective first and second regions, with the first region being more flexible (i.e., less stiff) than the second region. The first region, due to its greater flexibility, is more conformal to tissue than the second region. The less flexible (i.e., more stiff) second region imparts greater force against the tissue to urge the more flexible first region toward intimate tissue contact. In a preferred embodiment, the more flexible first region carries at least one therapeutic or diagnostic element.
摘要翻译：具有不对称机械特性的结构提供增强的能力，以支持与内部身体区域中的组织接触的治疗或诊断元件。支撑结构包括表现出影响组织接触的第一机械特性的第一区域以及围绕轴线与第一区域隔开的第二区域，该第二区域具有影响组织接触的第二机械特性，该第二机械特性不同于第一机械特性。在优选实施例中，第一和第二机械特性与相应的第一和第二区域的刚度相关，其中第一区域比第二区域更加柔性（即，较不硬）。第一个区域由于其更大的灵活性，比第二个区域更适合组织。较不柔性（即更硬）的第二区域赋予组织更大的力以促使更柔性的第一区域朝向紧密的组织接触。在优选实施方案中，更灵活的第一区域携带至少一种治疗或诊断元件。

5. 发明授权

US5925038A Expandable-collapsible electrode structures for capacitive coupling to tissue 失效
标题翻译：用于电容耦合到组织的可膨胀 - 可折叠电极结构
公开(公告)号：US5925038A
公开(公告)日：1999-07-20
申请号：US628928
申请日：1996-04-08
申请人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
发明人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
IPC分类号： A61B17/00 , A61B17/22 , A61B18/14 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61N1/06 , A61B17/39
CPC分类号： A61N1/06 , A61B18/1492 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839 , A61B2018/1253 , A61B2018/1472 , A61B2218/002
摘要： Electrode assemblies and associated systems employ a nonporous wall having an exterior for contacting tissue. The exterior peripherally surrounds an interior area. The wall is essentially free of electrically conductive material. The wall is adapted to assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. The assemblies and systems include a lumen that conveys a medium containing ions into the interior area. An element free of physical contact with the wall couples the medium within the interior area to a source of electrical energy to enable ionic transport of electrical energy from the source through the medium to the wall for capacitive coupling to tissue contacting the exterior of the wall.
摘要翻译：电极组件和相关系统采用具有用于接触组织的外部的无孔壁。外部外围围绕着内部区域。壁基本上不含导电材料。壁适于呈现具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的扩展几何形状。组件和系统包括将含有离子的介质输送到内部区域的内腔。与壁物理接触的元件将内部区域内的介质耦合到电能源，以使电能从源通过介质到壁的电能离子传输，用于电容耦合到与壁的外部接触的组织。

6. 发明授权

US5911739A Structures for supporting diagnostic or therapeutic elements in internal body regions 失效
标题翻译：用于支持内部身体区域的诊断或治疗元件的结构
公开(公告)号：US5911739A
公开(公告)日：1999-06-15
申请号：US738856
申请日：1996-10-28
申请人： Thomas F. Kordis , James G. Whayne , Dorin Panescu , David K. Swanson , Sidney D. Fleischman
发明人： Thomas F. Kordis , James G. Whayne , Dorin Panescu , David K. Swanson , Sidney D. Fleischman
IPC分类号： A61N1/00 , A61B17/36
CPC分类号： A61B5/0422 , A61B18/1492 , A61B5/6852 , A61B5/6858 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2018/00214 , A61B2018/00267 , A61B2018/00351 , A61B2018/00839 , A61B2018/1407 , A61B2018/1435 , A61B2018/1465 , A61B2562/0209 , A61B2562/043
摘要： Elongated spline members are threaded through a hub to form depending spline legs. In one embodiment, the spline members are threaded through a puncturable material on the hub. In another embodiment, the spline members are threaded through a slotted hub, which is then encapsulated by a sealing, elastomeric material. In another embodiment, multiple spline members are looped and woven together beyond a distal end of the hub, and the distal end of the hub serves to exert a force that maintains the woven relationship of the spline members. The spline legs, which radiate from the hub, preferable carry one or more diagnostic or therapeutic elements, such as electrodes. Preferably, a base constrains the terminal ends of the spline legs in a normally expanded geometry between the hub and base.
摘要翻译：细长的花键构件穿过轮毂以形成悬垂的花键腿。在一个实施例中，花键构件穿过轮毂上的可刺破材料。在另一个实施例中，花键构件穿过开槽的毂，然后由密封的弹性体材料包封。在另一个实施例中，多个花键构件环绕并且一起超越轮毂的远端编织，轮毂的远端用于施加维持花键构件的编织关系的力。从轮毂辐射的花键腿优选携带一个或多个诊断或治疗元件，例如电极。优选地，基座以轮毂和底座之间的正常展开的几何形状约束花键腿的末端。

7. 发明授权

US5846238A Expandable-collapsible electrode structures with distal end steering or manipulation 失效
标题翻译：具有远端转向或操纵的可膨胀 - 可折叠电极结构
公开(公告)号：US5846238A
公开(公告)日：1998-12-08
申请号：US628980
申请日：1996-04-08
申请人： Jerome Jackson , James G. Whayne , Patrick M. Owens , Thomas F. Kordis , Russell B. Thompson , Dorin Panescu , David K. Swanson
发明人： Jerome Jackson , James G. Whayne , Patrick M. Owens , Thomas F. Kordis , Russell B. Thompson , Dorin Panescu , David K. Swanson
IPC分类号： A61B17/00 , A61B17/22 , A61B18/14 , A61N1/05 , A61B17/39 , A61B5/04
CPC分类号： A61B18/1492 , A61N1/056 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839
摘要： Collapsible electrode assemblies and associated methods employing a structure having an axis and a distal end. The structure comprises a wall peripherally enclosing an interior. The structure is adapted to selectively assume an expanded geometry having a first maximum diameter about the axis and a collapsed geometry having a second maximum diameter about the axis less than the first maximum diameter. An electrically conductive material is carried by the wall, forming an electrode region adapted to conform to both the normally expanded geometry and the collapsed geometry of the structure. In one implementation, a flexing element in the interior of the structure bends within the interior along the axis of the structure to displace the distal end relative to the axis. In another implementation, a stilette element within the interior of the structure imparts axial force upon the distal end along the axis of the structure, thereby axially elongating or shortening the structure.
摘要翻译：可折叠电极组件和使用具有轴线和远端的结构的相关方法。该结构包括外围围绕内部的壁。该结构适于选择性地假设具有围绕该轴线的第一最大直径的膨胀几何形状，以及具有围绕小于第一最大直径的轴线的第二最大直径的折叠几何形状。导电材料由壁承载，形成适于符合正常膨胀的几何形状和结构的折叠几何形状的电极区域。在一个实施方式中，结构内部的弯曲元件沿着结构的轴线在内部弯曲，以使远端相对于轴线移位。在另一个实施方案中，结构内部的ile tte元件沿着结构的轴线向远端施加轴向力，从而轴向地延伸或缩短结构。

8. 发明授权

US06216043B1 Asymmetric multiple electrode support structures 失效
标题翻译：不对称多电极支撑结构
公开(公告)号：US06216043B1
公开(公告)日：2001-04-10
申请号：US08742569
申请日：1996-10-28
申请人： David K. Swanson , James G. Whayne , Thomas F. Kordis , Dorin Panescu
发明人： David K. Swanson , James G. Whayne , Thomas F. Kordis , Dorin Panescu
IPC分类号： A61N100
CPC分类号： A61B5/0422 , A61N1/056 , A61N1/0565 , A61N1/06 , A61N1/20 , A61N1/403
摘要： Multiple electrode support structures have asymmetric geometries, either axially, or radially, or both. The asymmetric support structures are assembled from spline elements that extend between a distal hub and a proximal base. In one embodiment, the spline elements are circumferentially spaced about the distal hub in a radially asymmetric fashion, creating a greater density of spline elements in one region of the structure than in another region. In the same or another embodiment, the spline elements are preformed in an axially asymmetric fashion along their lengths, creating a different geometry in their distal regions than in their proximal regions.
摘要翻译：多个电极支撑结构具有轴向或径向或两者的不对称几何形状。不对称支撑结构由在远端轮毂和近侧基座之间延伸的花键元件组装。在一个实施例中，花键元件以径向不对称的方式围绕远侧轮毂周向间隔开，在结构的一个区域中产生比在另一个区域更大的花键元件密度。在相同或另一个实施例中，花键元件沿它们的长度以轴向不对称的方式预成型，在它们的远侧区域中产生与其近端区域不同的几何形状。

9. 发明授权

US06428536B2 Expandable-collapsible electrode structures made of electrically conductive material 有权
标题翻译：由导电材料制成的可膨胀 - 可折叠电极结构
公开(公告)号：US06428536B2
公开(公告)日：2002-08-06
申请号：US09747276
申请日：2000-12-21
申请人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
发明人： Dorin Panescu , David K. Swanson , James G. Whayne , Thomas F. Kordis
IPC分类号： A61B1814
CPC分类号： A61N1/06 , A61B18/1492 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839 , A61B2018/1253 , A61B2018/1472 , A61B2218/002 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , C08L1/02
摘要： Electrode assemblies and associated systems employ a nonporous wall having an exterior for contacting tissue. The exterior peripherally surrounds an interior area. The wall is essentially free of electrically conductive material. The wall is adapted to assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. The assemblies and systems include a lumen that conveys a medium containing ions into the interior area. An element free of physical contact with the wall couples the medium within the interior area to a source of electrical energy to enable ionic transport of electrical energy from the source through the medium to the wall for capacitive coupling to tissue contacting the exterior of the wall.
摘要翻译：电极组件和相关系统采用具有用于接触组织的外部的无孔壁。外部外围围绕着内部区域。该壁基本上不含导电材料。壁适于呈现具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的扩展几何形状。组件和系统包括将含有离子的介质输送到内部区域的内腔。与壁物理接触的元件将内部区域内的介质耦合到电能源，以使电能从源通过介质到壁的电能离子传输，用于电容耦合到与壁的外部接触的组织。

10. 发明授权

US5891136A Expandable-collapsible mesh electrode structures 失效
标题翻译：可膨胀 - 可折叠网状电极结构
公开(公告)号：US5891136A
公开(公告)日：1999-04-06
申请号：US630721
申请日：1996-04-08
申请人： David McGee , Patrick M. Owens , James G. Whayne , Russell B. Thompson , Thomas F. Kordis , David K. Swanson , Dorin Panescu
发明人： David McGee , Patrick M. Owens , James G. Whayne , Russell B. Thompson , Thomas F. Kordis , David K. Swanson , Dorin Panescu
IPC分类号： A61B17/00 , A61B17/22 , A61B18/14 , A61N1/05 , A61B17/39
CPC分类号： A61N1/056 , A61B18/1492 , A61B2017/00053 , A61B2017/00243 , A61B2017/22051 , A61B2017/22061 , A61B2018/00083 , A61B2018/00095 , A61B2018/00107 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00839
摘要： Collapsible electrode assemblies and associated methods employ an array of filaments assembled to form a mesh structure. The mesh structure is adapted to selectively assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. Preferably, at least one of the filaments includes an electrically conductive material adapted for coupling to a source of ablation energy for transmitting ablation energy.
摘要翻译：可折叠电极组件和相关联的方法采用组装成形成网格结构的细丝阵列。网格结构适于选择性地假设具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的扩展几何形状。优选地，所述长丝中的至少一个包括适于耦合到用于传导消融能量的消融能量源的导电材料。

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