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1. 发明申请

WO2007067941A2 ASSESSMENT OF ELECTRODE COUPLING FOR TISSUE ABLATION 审中-公开
标题翻译：用于组织脱落的电极耦合评估
公开(公告)号：WO2007067941A2
公开(公告)日：2007-06-14
申请号：PCT/US2006/061714
申请日：2006-12-06
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , PAUL, Saurav , BELHE, Kedar, Ravindra , CAO, Hong , THAO, Chou
发明人： PAUL, Saurav , BELHE, Kedar, Ravindra , CAO, Hong , THAO, Chou
IPC分类号： A61B18/18
CPC分类号： A61B18/1206 , A61B18/1492 , A61B34/20 , A61B2018/00303 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/0075 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2090/064 , A61B2090/065
摘要： An electrode catheter and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter comprises an electrode adapted to apply electrical energy. A measurement circuit is adapted to measure impedance between the electrode and ground as the electrode approaches a target tissue. A processor determines a contact and coupling condition for the target tissue based at least in part on reactance of the impedance measured by the measurement circuit. In another exemplary embodiment, the electrode catheter determines the contact and coupling condition based at least in part on a phase angle of the impedance.
摘要翻译：公开了用于评估电极 - 组织接触和耦合的电极导管和方法。示例性电极导管包括适于施加电能的电极。测量电路适于在电极接近目标组织时测量电极和地之间的阻抗。处理器至少部分地基于由测量电路测量的阻抗的电抗来确定目标组织的接触和耦合条件。在另一个示例性实施例中，电极导管至少部分地基于阻抗的相位角来确定接触和耦合条件。

2. 发明申请

WO2007067939A2 ASSESSMENT OF ELECTRODE COUPLING FOR TISSUE ABLATION 审中-公开
公开(公告)号：WO2007067939A2
公开(公告)日：2007-06-14
申请号：PCT/US2006/061712
申请日：2006-12-06
申请人： ST. JUDE MEDICAL , ATRIAL FIBRILLATION DIVISION, INC. , PAUL, Saurav , BELHE, Kedar, Ravindra , CAO, Hong , THAO, Chou
发明人： PAUL, Saurav , BELHE, Kedar, Ravindra , CAO, Hong , THAO, Chou
IPC分类号： A61B18/18
CPC分类号： A61B18/1206 , A61B18/1492 , A61B34/20 , A61B2018/00303 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/0075 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2090/064 , A61B2090/065
摘要： An electrode catheter and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter comprises an electrode adapted to apply electrical energy. A measurement circuit is adapted to measure impedance between the electrode and ground as the electrode approaches a target tissue. A processor determines a contact and coupling condition for the target tissue based at least in part on reactance of the impedance measured by the measurement circuit. In another exemplary embodiment, the electrode catheter determines the contact and coupling condition based at least in part on a phase angle of the impedance.

3. 发明申请

WO2007002004A3 ABLATION CATHETER WITH FLUID DISTRIBUTION STRUCTURES 审中-公开
公开(公告)号：WO2007002004A3
公开(公告)日：2007-01-04
申请号：PCT/US2006/023854
申请日：2006-06-19
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , CAO, Hong , THAO, Chou , BELHE, Kedar, Ravindra , PAUL, Saurav , STANGENES, Todd
发明人： CAO, Hong , THAO, Chou , BELHE, Kedar, Ravindra , PAUL, Saurav , STANGENES, Todd
IPC分类号： A61B18/04 , A61F7/00
摘要： An ablation catheter (22) has improved fluid distribution structures. An ablation section at a distal end (12) of the catheter (22) is designed to provide a more uniform fluid flow emanating from the catheter (22). By creating a uniform fluid flow, a more uniform tissue lesion results and the possibility of charring the tissue is reduced. A combination of mesh material (142) layers, porous materials (354), and dispersion channels or openings (346) are used to achieve the uniform flow. The amount of fluid used as a virtual electrode to ablate the tissue is greatly reduced with the present invention. Further, the catheter (22) may be used to create a single, uniform linear lesion by successive application of energy to adjacent portions of the ablation section, thus reducing the power required to create the desired lesion.

4. 发明申请

WO2007067628A1 ASSESSMENT OF ELECTRODE COUPLING FOR TISSUE ABLATION 审中-公开
标题翻译：电器联合电击组织评估
公开(公告)号：WO2007067628A1
公开(公告)日：2007-06-14
申请号：PCT/US2006/046565
申请日：2006-12-06
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , PAUL, Saurav , CAO, Hong , BELHE, Kedar, Ravindra
发明人： PAUL, Saurav , CAO, Hong , BELHE, Kedar, Ravindra
IPC分类号： A61N1/00
CPC分类号： A61B18/1206 , A61B18/1492 , A61B34/20 , A61B2018/00303 , A61B2018/00357 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/0075 , A61B2018/00755 , A61B2018/00869 , A61B2018/00875 , A61B2090/064 , A61B2090/065
摘要： An electrode catheter (14) and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter (14) comprises an electrode (20) adapted to apply electrical energy. A measurement circuit (42) is adapted to measure impedance between the electrode (20) and ground as the electrode approaches a target tissue (24). A processor (50) determines a contact and coupling condition for the target tissue (24) based at least in part on reactance of the impedance measured by the measurement circuit (42). In another exemplary embodiment, the electrode catheter (14) determines the contact and coupling condition based at least in part on a phase angle of the impedance.
摘要翻译：公开了一种电极导管（14）和用于评估电极组织接触和耦合的方法。示例性电极导管（14）包括适于施加电能的电极（20）。测量电路（42）适于在电极接近目标组织（24）时测量电极（20）和地面之间的阻抗。处理器（50）至少部分地基于由测量电路（42）测量的阻抗的电抗来确定目标组织（24）的接触和耦合条件。在另一示例性实施例中，电极导管（14）至少部分地基于阻抗的相位角来确定接触和耦合条件。

5. 发明申请

WO2008045831A3 ROBOTIC SURGICAL SYSTEM AND METHOD FOR AUTOMATIC CREATION OF ABLATION LESIONS 审中-公开
公开(公告)号：WO2008045831A3
公开(公告)日：2008-04-17
申请号：PCT/US2007/080705
申请日：2007-10-08
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , HAUCK, John, A. , SCHWEITZER, Jeffrey, A. , BELHE, Kedar, Ravindra , BURRELL, Jeffrey, L.
发明人： HAUCK, John, A. , SCHWEITZER, Jeffrey, A. , BELHE, Kedar, Ravindra , BURRELL, Jeffrey, L.
IPC分类号： A61B18/00
摘要： A system (10) for ablating tissue includes an ablation catheter (12) for insertion into the body of a patient and a robotic controller (24) for moving the catheter (12) within the body. The robotic controller (24) advances the catheter (12) until the catheter (12) contacts the tissue surface (82), maintains contact between the catheter (12) and the tissue surface (82), and moves the catheter (12) along a predetermined path (200) to create a substantially continuous lesion of ablated tissue. A display device (156) may be used to present a graphical representation of an area of tissue to be ablated. A user interface (166) permits selection of a plurality of treatment points (202) on the graphical representation. The interface (166) is preferably coupled to the controller (24) and catheter (12) such that the controller (24) may cause the catheter (12) to automatically ablate tissue.

6. 发明申请

WO2008045829A2 ROBOTIC SURGICAL SYSTEM AND METHOD FOR DIAGNOSTIC DATA MAPPING 审中-公开
标题翻译：机器人手术系统和诊断数据映射方法
公开(公告)号：WO2008045829A2
公开(公告)日：2008-04-17
申请号：PCT/US2007/080703
申请日：2007-10-08
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , HAUCK, John, A. , SCHWEITZER, Jeffrey, A. , BELHE, Kedar, Ravindra
发明人： HAUCK, John, A. , SCHWEITZER, Jeffrey, A. , BELHE, Kedar, Ravindra
IPC分类号： A61B5/04 , A61B18/18
CPC分类号： A61B19/2203 , A61B5/04011 , A61B5/06 , A61B5/6885 , A61B5/7425 , A61B5/7475 , A61B34/20 , A61B34/30 , A61B34/71 , A61B2017/00026 , A61B2034/105 , A61B2034/2051 , A61B2034/2053 , A61B2034/2072 , A61B2034/301 , A61B2034/303 , A61B2034/742 , A61B2090/064 , A61B2090/3784 , A61M25/0105
摘要： A method of generating a diagnosis map of at least a portion of the heart (152) includes inserting an electrode (154) within the portion of a heart (152), robotically moving the electrode (154) therein, measuring electrophysiology information at a point on the surface (82) of the heart, associating the measured electrophysiology information with position information for the point on the surface (82) of the heart, repeating the measuring and associating steps for a plurality of points on the surface (82) of the heart, thereby generating a plurality of surface diagnostic data points, and generating the diagnosis map therefrom. The electrode (154) may be moved within the heart randomly, pseudo randomly, or according to one or more predetermined patterns. A three dimensional model of the portion of the heart (152) may be provided and presented as a graphical representation, either with or without information indicative of the measured electrophysiology information superimposed thereon.
摘要翻译：产生心脏（152）的至少一部分的诊断图的方法包括在心脏部分内插入电极（154），在其中机械地移动电极（154），在一点测量电生理学信息在心脏的表面（82）上，将所测量的电生理学信息与心脏表面（82）上的点的位置信息相关联，重复测量和关联在心脏的表面（82）上的多个点的测量和关联步骤从而生成多个表面诊断数据点，并从其生成诊断图。电极（154）可随机移动，随机地伪随机，或根据一个或多个预定模式移动。可以提供心脏部分（152）的三维模型并将其呈现为图形表示，其具有或不具有指示叠加在其上的所测量的电生理学信息的信息。

7. 发明申请

WO2008045832A2 ROBOTIC SURGICAL SYSTEM AND METHOD FOR AUTOMATED THERAPY DELIVERY 审中-公开
标题翻译：机器人手术系统及自动化治疗方法
公开(公告)号：WO2008045832A2
公开(公告)日：2008-04-17
申请号：PCT/US2007/080706
申请日：2007-10-08
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , HAUCK, John, A. , SCHWEITZER, Jeffrey, A. , BELHE, Kedar, Ravindra
发明人： HAUCK, John, A. , SCHWEITZER, Jeffrey, A. , BELHE, Kedar, Ravindra
IPC分类号： A61B18/18
CPC分类号： A61B34/71 , A61B5/6885 , A61B34/20 , A61B34/30 , A61B2017/00026 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/301 , A61B2034/742 , A61B2090/064 , A61B2090/3784 , A61M25/0105
摘要： A method of navigating a medical device (12) through a body of a patient includes providing a topography of at least a portion of the body, accepting user input defining a navigation path (200), robotically navigating the medical device (12) to a starting point on the path, and robotically navigating the medical device (12) along the navigation path (200) to an endpoint. Waypoints (202) defining the navigation path may be input on a graphical representation of the topography using a user interface such as a pointing device or touchscreen. The navigation path (200) may also be defined by tracing a substantially continuous path on the graphical representation. A therapy may be administered while robotically navigating the medical device (12) along the navigation path, either forward or in reverse, or while navigating the medical device (12) along a return path defined by a plurality of virtual breadcrumbs generated as the medical device (12) traverses the navigation path (200).
摘要翻译：通过患者身体导航医疗装置（12）的方法包括提供身体的至少一部分的形貌，接受定义导航路径（200）的用户输入，将医疗装置（12）自动导航到并且沿着导航路径（200）将医疗设备（12）机器人地导航到端点。定义导航路径的路点（202）可以使用诸如指点设备或触摸屏的用户界面在地形的图形表示上输入。还可以通过在图形表示上跟踪基本上连续的路径来定义导航路径（200）。治疗可以沿着导航路径机动地导航医疗装置（12），前向或反向，或者沿着沿着由作为医疗装置生成的多个虚拟面包屑所限定的返回路径导航医疗装置（12）（12）穿过导航路径（200）。

8. 发明申请

WO2007035306A2 SYSTEM AND METHOD FOR THREE-DIMENSIONAL MAPPING OF ELECTROPHYSIOLOGY INFORMATION 审中-公开
标题翻译：电生理信息三维映射的系统与方法
公开(公告)号：WO2007035306A2
公开(公告)日：2007-03-29
申请号：PCT/US2006/035290
申请日：2006-09-12
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. , AFONSO, Valtino, X. , BELHE, Kedar, Ravindra , SCHWEITZER, Jeffrey, A.
发明人： AFONSO, Valtino, X. , BELHE, Kedar, Ravindra , SCHWEITZER, Jeffrey, A.
IPC分类号： A61B5/04
CPC分类号： A61B5/0422 , A61B5/04012 , A61B5/044 , A61B5/0452
摘要： An electrophysiology apparatus (8) is used to measure electrical activity occurring in a heart (10) of a patient (11) and to visualize the electrical activity and/or information related to the electrical activity. A three dimensional map of the electrical activity and/or the information related to the electrical activity is created. Colors, shades of colors, and/or grayscales are assigned to values of the parameters and colors corresponding to the parameters for the electrograms sampled by the electrodes (e.g., 12, 14, 16, 17, 18, 19, 22) are updated on the three dimensional model (62).
摘要翻译：电生理学装置（8）用于测量在患者（11）的心脏（10）中发生的电活动并且可视化与电活动相关的电活动和/或信息。创建电活动的三维图和/或与电活动有关的信息。将颜色，色调和/或灰度等级分配给参数的值和对应于由电极采样的电描记图（例如，12,14,16,17,18,19,22）的参数的参数的值被更新为三维模型（62）。

9. 发明申请

WO2005072488A2 BRUSH ELECTRODE AND METHOD FOR ABLATION 审中-公开
标题翻译： BRUSH电极和方法
公开(公告)号：WO2005072488A2
公开(公告)日：2005-08-11
申请号：PCT/US2005/000767
申请日：2005-01-14
申请人： ST. JUDE MEDICAL, DAIG DIVISION, INC. , PAUL, Saurav , BELHE, Kedar, Ravindra , CAO, Hong , THAO, Chou
发明人： PAUL, Saurav , BELHE, Kedar, Ravindra , CAO, Hong , THAO, Chou
IPC分类号： A61B18/14
CPC分类号： A61B18/1402 , A61B2018/143 , A61B2018/1472
摘要： A brush electrode ( e.g ., 10) and a method for using the brush electrode for tissue ablation are disclosed. The brush electrode comprises a plurality of flexible filaments or bristles ( e.g ., 26) for applying ablative energy to target tissue (46) during the formation of spot or continuous linear lesions. Interstitial spaces (156) are defined among the filaments of the brush electrode, and the interstitial spaces are adapted to direct conductive or nonconductive fluid (34), when present, toward the distal ends of the brush filaments. The brush electrode facilitates electrode tissue contact in target tissue having flat or contoured surfaces. The flexible filaments may be selectively trimmed to give a desired tip configuration or a desired standoff distance between the tissue and the conductive filaments in the brush electrode. Also, the filaments may be grouped into clusters. A shielded tip brush electrode ( e.g ., 120), including a flexible boot ( e.g ., 142), is also disclosed.
摘要翻译：公开了一种刷电极（例如，10）和用于组织消融的刷电极的使用方法。刷电极包括多个柔性细丝或刷毛（例如26），用于在形成斑点或连续线性病变期间向靶组织（46）施加烧蚀能量。间隙空间（156）被限定在刷电极的长丝之间，并且间隙空间适于使导电或非导电流体（34）当存在时朝向刷丝的远端引导。刷电极有助于在具有平坦或轮廓的表面的靶组织中的电极组织接触。可以选择性地修剪柔性细丝以给出组织和刷电极中的导电细丝之间的期望的尖端构型或期望的间隔距离。此外，丝可以分组成簇。还公开了一种包括柔性靴（例如142）的屏蔽尖端刷电极（例如120）。

10. 发明申请

WO2007047360A2 DYNAMIC CONTACT ASSESSMENT FOR ELECTRODE CATHETERS 审中-公开
标题翻译：电极导体动态接触评估
公开(公告)号：WO2007047360A2
公开(公告)日：2007-04-26
申请号：PCT/US2006/039881
申请日：2006-10-13
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, I NC. , PAUL, Saurav , CHOU, Thao , BELHE, Kedar, Ravindra , HEIMBECHER, Reed, R.
发明人： PAUL, Saurav , CHOU, Thao , BELHE, Kedar, Ravindra , HEIMBECHER, Reed, R.
IPC分类号： A61B5/04 , A61B18/14 , A61B5/103 , A61B5/117
CPC分类号： A61B5/036 , A61B5/061 , A61B5/6885 , A61B18/1492 , A61B2018/00351 , A61B2090/065
摘要： An electrode catheter and a method for assessing catheter-tissue contact for tissue ablation are disclosed. An exemplary electrode catheter comprises a flexible catheter shaft. At least one piezoelectric sensor is oriented coaxial to the flexible catheter shaft. The at least one piezoelectric sensor is responsive to movement of the flexible catheter shaft by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one piezoelectric sensor. The output device receives the electrical signals for dynamically assessing a level of contact between the flexible catheter shaft and a moving tissue. In another exemplary embodiment, the system may be implemented in a hydrodynamic environment.
摘要翻译：公开了电极导管和用于评估用于组织消融的导管 - 组织接触的方法。示例性电极导管包括柔性导管轴。至少一个压电传感器与柔性导管轴同轴地定向。至少一个压电传感器通过产生对应于移动量的电信号来响应柔性导管轴的移动。该系统还可以包括电连接到至少一个压电传感器的输出装置。输出装置接收用于动态评估柔性导管轴和移动组织之间的接触程度的电信号。在另一个示例性实施例中，系统可以在流体动力学环境中实现。

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