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1. 发明授权

US5358849A Monoclonal antibody recognizing membrane phospholipase A.sub.2 and immunoassay of membrane phospholipase A.sub.2 失效
标题翻译：单克隆抗体识别膜磷脂酶A2和膜磷脂酶A2的免疫测定
公开(公告)号：US5358849A
公开(公告)日：1994-10-25
申请号：US53350
申请日：1993-04-28
申请人： Nobuo Yoshida , Misao Ide , Masao Kono , Akiko Kanda
发明人： Nobuo Yoshida , Misao Ide , Masao Kono , Akiko Kanda
IPC分类号： G01N33/573 , A61K39/395 , C07K16/40 , C12N5/10 , C12N5/20 , C12N15/02 , C12P21/08 , C12R1/91 , G01N33/577 , C07K15/28 , C12N5/16 , G01N33/541
CPC分类号： C07K16/40
摘要： The present invention first provides monoclonal antibodies recognizing membrane phospholipase A.sub.2, namely, monoclonal antibodies PL-49, PL-71, PL-76, and PL-78, hybridomas producing them, methods for producing them, and immunoassays of membrane phospholipase A.sub.2 using them.The immunoassay of PLA.sub.2 M is useful for the diagnosis of articular rheumatism, cancers, and a wide variety of inflammatory states.
摘要翻译：本发明首先提供识别膜磷脂酶A2的单克隆抗体，即单克隆抗体PL-49，PL-71，PL-76和PL-78，产生它们的杂交瘤，制备它们的方法和使用它们的膜磷脂酶A2的免疫测定。 PLA2M的免疫测定可用于诊断关节风湿病，癌症和多种炎症状态。

2. 发明授权

US4327072A Tyrosylated proinsulin C-peptide derivatives 失效
标题翻译：酪氨酸化胰岛素原C肽衍生物
公开(公告)号：US4327072A
公开(公告)日：1982-04-27
申请号：US97671
申请日：1979-11-27
申请人： Ken Inouye , Masao Kono , Nobuo Yoshida , Masuhisa Nakamura , Tadashi Okabayashi , Ken'ichi Igano
发明人： Ken Inouye , Masao Kono , Nobuo Yoshida , Masuhisa Nakamura , Tadashi Okabayashi , Ken'ichi Igano
IPC分类号： G01N33/53 , C07C67/00 , C07C231/00 , C07K14/00 , C07K14/62 , G01N33/534 , G01N33/74 , G01N33/56 , A61K43/00 , C07C103/52
CPC分类号： C07K14/62 , G01N33/534 , G01N33/74 , G01N2333/62 , Y02P20/55
摘要： The disclosed peptide derivative of the formula:Y--Tyr--Gly--RWherein, Y represents a hydrogen atom or an amino protecting group, Tyr represents a tyrosine residue wherein at least one of the hydrogen atoms on the phenyl ring may be substituted by a radioactive iodine, Gly represents a glycine residue, and R represents a peptide residue corresponding to an amino acid sequence which includes at least positions 7 through 21 of human proinsulin C-peptide proves to be useful for determining C-peptide level in human serum.
摘要翻译：所公开的下式的肽衍生物：Y-Tyr-Gly-R其中，Y表示氢原子或氨基保护基，Tyr表示酪氨酸残基，其中苯环上的至少一个氢原子可被放射性碘，Gly表示甘氨酸残基，R表示对应于氨基酸序列的肽残基，该氨基酸序列至少包含人胰岛素原C-肽的至少7至21位，可用于测定人血清中的C-肽水平。

3. 发明授权

US08537505B2 Magnetoresistive effect head having a free layer and a magnetic domain control layer that applies a magnetic field more strongly in an upper part of the free layer 有权
标题翻译：具有自由层和磁畴控制层的磁阻效应头，其在自由层的上部更强地施加磁场
公开(公告)号：US08537505B2
公开(公告)日：2013-09-17
申请号：US12784405
申请日：2010-05-20
申请人： Masato Shiimoto , Kan Yasui , Nobuo Yoshida , Hiroyuki Takazawa
发明人： Masato Shiimoto , Kan Yasui , Nobuo Yoshida , Hiroyuki Takazawa
IPC分类号： G11B5/39 , G11B5/11
CPC分类号： G11B5/3932 , B82Y25/00 , G01R33/093 , G01R33/098 , H01L43/08 , H01L43/10
摘要： According to one embodiment, a magnetoresistive effect head includes a lower magnetic shield provided on a substrate, a magnetoresistive effect film laminated from a pinned layer with a pinned direction of magnetization, an intermediate layer, a free layer having a varying direction of magnetization controlled by an applied external magnetic field, a magnetic domain control layer formed with an intervening insulation layer on both sides in a track width direction of the magnetoresistive effect film, an upper magnetic shield, and electrodes for directing sense current flow in a direction perpendicular to a film surface of the magnetoresistive effect film, wherein a magnetic field applied by the magnetic domain control layer to a region away from an ABS of the free layer is at least 1.4 times larger than a magnetic field applied by the magnetic domain control layer to a region near the ABS of the free layer.
摘要翻译：根据一个实施例，磁阻效应头包括设置在基板上的下磁屏蔽，从具有钉扎方向的钉扎层层压的磁阻效应膜，中间层，具有变化的磁化方向的自由层，施加的外部磁场，在磁阻效应膜的磁道宽度方向上在两侧形成有中间绝缘层的磁畴控制层，上磁屏蔽和用于引导垂直于膜的方向的感测电流的电极磁阻效应膜的表面，其中由磁畴控制层施加到远离自由层的ABS的区域的磁场比由磁畴控制层施加到接近的区域的磁场的至少大1.4倍 ABS的自由层。

4. 发明申请

US20120187079A1 METHOD FOR MANUFACTURING A MAGNETIC SENSOR HAVING A FLAT UPPER SHIELD 审中-公开
标题翻译：用于制造具有平坦上层屏蔽的磁传感器的方法
公开(公告)号：US20120187079A1
公开(公告)日：2012-07-26
申请号：US13010908
申请日：2011-01-21
申请人： Hideki Mashima , Nobuo Yoshida
发明人： Hideki Mashima , Nobuo Yoshida
IPC分类号： G11B5/127 , C23F1/00
CPC分类号： G11B5/398 , G01R33/098 , G11B5/3163 , G11B5/3912 , G11B5/3932
摘要： A method for manufacturing a magnetic sensor that has a flat upper shield. A sensor stack is formed with a sensor capping layer at its top and a first CMP stop layer over the sensor capping layer and a mask formed over the CMP stop layer. A hard bias layer and second CMP stop layer are deposited over the sensor stack, capping layer, first CMP stop layer and mask. A chemical mechanical polishing process is then performed to remove the mask, leaving a portion of the hard bias layer exposed between the first and second CMP stop layers. An ion milling is then performed to etch back the exposed portions of the hard magnetic bias layer. A reactive ion etching is then performed to remove the remaining first and second CMP top layers. An upper shield can then be formed on a substantially flat surface.
摘要翻译：一种制造具有平坦的上屏蔽的磁传感器的方法。传感器堆叠在其顶部形成有传感器覆盖层，并且在传感器覆盖层上方形成第一CMP停止层，并且在CMP停止层上形成掩模。在传感器堆叠，封盖层，第一CMP停止层和掩模上沉积硬偏压层和第二CMP停止层。然后执行化学机械抛光工艺以去除掩模，使得一部分硬偏压层暴露在第一和第二CMP停止层之间。然后进行离子铣削以蚀刻硬磁偏置层的暴露部分。然后执行反应离子蚀刻以去除剩余的第一和第二CMP顶层。然后可以在基本平坦的表面上形成上屏蔽。

5. 发明授权

US07881022B2 Magnetic head and method for fabricating the same 有权
标题翻译：磁头及其制造方法
公开(公告)号：US07881022B2
公开(公告)日：2011-02-01
申请号：US11788038
申请日：2007-04-17
申请人： Hisako Takei , Nobuo Yoshida , Hiroyuki Hoshiya , Taku Shintani
发明人： Hisako Takei , Nobuo Yoshida , Hiroyuki Hoshiya , Taku Shintani
IPC分类号： G11B5/39
CPC分类号： G01R33/093 , B82Y25/00 , G11B5/3163 , G11B5/398 , Y10T29/49021
摘要： Embodiments in accordance with the present invention provide a sensor to produce high output with a small track width. Particular embodiments include forming a magnetoresistive sensor of a read head to be substantially vertical in its upper portion and gently upwardly convexly curved in its lower portion.
摘要翻译：根据本发明的实施例提供一种用于产生具有小轨道宽度的高输出的传感器。具体实施例包括形成读头的磁阻传感器在其上部基本垂直并且在其下部中轻轻地向上凸起地弯曲。

6. 发明申请

US20080218910A1 Magnetic detection element and manufacturing method thereof 有权
标题翻译：磁性检测元件及其制造方法
公开(公告)号：US20080218910A1
公开(公告)日：2008-09-11
申请号：US12012635
申请日：2008-02-04
申请人： Shuichi Kojima , Satoru Okamoto , Nobuo Yoshida , Katsuro Watanabe
发明人： Shuichi Kojima , Satoru Okamoto , Nobuo Yoshida , Katsuro Watanabe
IPC分类号： G11B5/33
CPC分类号： G11B5/3163 , B82Y25/00 , G01R33/093 , G11B5/3932 , G11B5/398 , H01L43/12
摘要： Embodiments of the present invention help to reduce etching damage at end parts of a magnetoresistive sensor in ion beam etching. According to one embodiment, ion beam etching (IBE) is used in a magnetoresistive sensor track width forming step. This IBE irradiates Ar ion beam to a substrate in a state that the substrate is inclined and further rotates the substrate about its normal as a rotational axis. In a conventional track width forming step, the IBE irradiates the Ar ion beam to the substrate all the time while the IBE is rotating the substrate. By contrast, the IBE according to embodiments of the present invention irradiates the Ar ion beam to the substrate only in a predetermined specific angular range.
摘要翻译：本发明的实施例有助于减少离子束蚀刻中的磁阻传感器端部处的蚀刻损伤。根据一个实施例，在磁阻传感器轨道宽度形成步骤中使用离子束蚀刻（IBE）。该IBE在基板倾斜的状态下将Ar离子束照射到基板，并且进一步使基板围绕其正常旋转轴线旋转。在传统的轨道宽度形成步骤中，IBE在基板旋转的同时始终将Ar离子束照射到衬底上。相比之下，根据本发明的实施例的IBE仅在预定的特定角度范围内将Ar离子束照射到衬底。

7. 发明授权

US07145750B2 Perpendicular magnetic recording head and perpendicular magnetic recording and reproducing system 有权
公开(公告)号：US07145750B2
公开(公告)日：2006-12-05
申请号：US10335884
申请日：2003-01-03
申请人： Hisashi Kimura , Kazuhiro Nakamoto , Yoshiaki Kawato , Nobuo Yoshida
发明人： Hisashi Kimura , Kazuhiro Nakamoto , Yoshiaki Kawato , Nobuo Yoshida
IPC分类号： G11B5/127
CPC分类号： G11B5/3967 , G11B5/09 , G11B5/1278 , G11B5/187 , G11B5/313 , G11B2005/0029
摘要： There is provided a perpendicular magnetic recording and reproducing system in which the overwrite erase ratio of a perpendicular magnetic head has been improved to prevent the deterioration of an overwrite property. In the perpendicular magnetic head, a third magnetic pole composed of a soft magnetic layer is formed on the leading side of a recording magnetic pole via a non-magnetic layer, thereby reducing magnetic interference from magnetization on a medium with the recording magnetic pole and preventing the deterioration of the overwrite property.

8. 发明授权

US07142392B2 Thin film head, producing method thereof and magnetic disk apparatus 失效
标题翻译：薄膜头及其制造方法和磁盘装置
公开(公告)号：US07142392B2
公开(公告)日：2006-11-28
申请号：US11002498
申请日：2004-12-03
申请人： Shigekazu Ohtomo , Moriaki Fuyama , Nobuo Yoshida , Hiroshi Fukui
发明人： Shigekazu Ohtomo , Moriaki Fuyama , Nobuo Yoshida , Hiroshi Fukui
IPC分类号： G11B5/147
CPC分类号： B82Y25/00 , B82Y10/00 , G11B5/012 , G11B5/3116 , G11B5/313 , G11B5/332 , G11B5/3903 , G11B5/3967 , G11B2005/3996
摘要： A thin film head having reading part and recording part having an upper magnetic pole front end layer and a lower magnetic pole having a lower magnetic main layer, a lower magnetic pole front end portion on the lower magnetic main layer, and a projection step portion on the lower magnetic pole front end portion. The upper magnetic pole front end layer has a magnetic pole expansion position and a length from an air bearing surface to the magnetic pole expansion position is less than a length from the air bearing surface to gap depth position of the lower magnetic pole front end portion.
摘要翻译：具有读取部分的薄膜头和具有上磁极前端层的记录部分和具有下磁性主层的下磁极，下磁性主体层上的下磁极前端部分和在下磁性主体层上的突出台阶部分下磁极前端部分。上磁极前端层具有磁极膨胀位置，从空气支承面到磁极伸长位置的长度小于从下侧磁极前端部的空气轴承面到间隙深度位置的长度。

9. 发明授权

US06171989B2 Silver-colored sintered product and method of producing the same 失效
标题翻译：银色烧结产品及其制造方法
公开(公告)号：US06171989B2
公开(公告)日：2001-01-09
申请号：US08878582
申请日：1997-06-19
申请人： Nobuo Yoshida
发明人： Nobuo Yoshida
IPC分类号： C04B3558
CPC分类号： C04B35/6455 , A44C27/003 , C04B35/5611 , C04B35/58071 , G04B37/22
摘要： A silver-colored sintered product having excellent corrosion resistance containing titanium, carbon and boron as indispensable constituent elements, and including in the sintered product composition a titanium boride phase or a boride phase which contains titanium as a chief metal element and a titanium carbide phase or a carbide phase which contains titanium as a chief metal element and a method of producing the same. The sintered product has a flexural strength of not smaller than 700 MPa, a Vickers' hardness of not smaller than 9.0 GPa and a fracture toughness of not smaller than 5.0 MPa·m½.
摘要翻译：一种具有优良耐腐蚀性的银色烧结产品，其中包含钛，碳和硼作为不可或缺的组成元素，并且在烧结产品组合物中包括钛/硼化物相或含有钛作为主要金属元素的硼化物相和碳化钛相或包含钛作为主要金属元素的碳化物相及其制造方法。该烧结体的弯曲强度为700MPa以上，维氏硬度为9.0GPa以上，断裂韧性为5.0MPa·m 1/2以上。

10. 发明授权

US09230574B2 Magnetoresistive head with a CPP structure having suppressed side reading 有权
标题翻译：具有抑制侧读的CPP结构的磁阻头
公开(公告)号：US09230574B2
公开(公告)日：2016-01-05
申请号：US12631295
申请日：2009-12-04
申请人： Nobuo Yoshida , Katsuro Watanabe , Masahiro Ousugi , Atsushi Kato
发明人： Nobuo Yoshida , Katsuro Watanabe , Masahiro Ousugi , Atsushi Kato
IPC分类号： G11B5/39 , B82Y10/00 , B82Y25/00
CPC分类号： G11B5/3909 , B82Y10/00 , B82Y25/00 , G11B5/3932 , G11B2005/3996 , Y10T29/49032
摘要： According to one embodiment, a CPP structure magnetoresistive head includes a magnetoresistive sensor film between a lower shield layer and an upper shield layer and a longitudinal biasing layer disposed at each side of the magnetoresistive sensor film via a read track width defining insulator film. In the stripe height direction, the length of the longitudinal biasing layer is longer than the length of a second ferromagnetic layer in which its magnetization rotates in response to the external magnetic field. The second ferromagnetic layer is one of the layers comprising the magnetoresistive sensor film. At a stripe height, the surface of each longitudinal biasing layer has a step to change the thickness thereof across the step so that the air bearing surface section thereof has a larger thickness than any other section. Other structures using a magnetoresistive head and methods of production thereof are described as well.
摘要翻译：根据一个实施例，CPP结构磁阻头包括在下屏蔽层和上屏蔽层之间的磁阻传感器膜和经由读磁道宽度限定绝缘膜设置在磁阻传感器膜的每一侧的纵向偏置层。在条带高度方向上，纵向偏置层的长度长于其磁化响应于外部磁场而旋转的第二铁磁层的长度。第二铁磁层是包括磁阻传感器膜的层之一。在条带高度处，每个纵向偏置层的表面具有改变其横跨该台阶的厚度的步骤，使得其空气轴承表面部分具有比任何其它部分更大的厚度。还描述了使用磁阻头的其它结构及其生产方法。

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