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    • 3. 发明授权
    • Safety syringe preventing the needle storage mechanism from being operated before use
    • 防止针存储机构在使用前被操作的安全注射器
    • US09408982B2
    • 2016-08-09
    • US11991807
    • 2006-09-12
    • Minoru SanoYoshihisa Hama
    • Minoru SanoYoshihisa Hama
    • A61M5/32A61M5/315A61M5/50
    • A61M5/322A61M5/31501A61M5/31505A61M2005/31506A61M2005/31508A61M2005/3231A61M2005/5073
    • To provide a syringe with a needle storage mechanism in which the needle storage mechanism is not activated before use. A safety syringe including an injection barrel 1 having a connecting portion 11 at the distal end and an opening at the proximal end thereof, a needle assembly B having an injection needle 5 and a needle base 6 fixed to the proximal end of the injection needle 5 and being connected to the connecting portion 11, a gasket 2 provided liquid-tightly and slidably in the injection barrel, a plunger 3 being connected to the proximal end of the gasket 2 and joining means 21 provided at the distal portion of the gasket 2 or the plunger 3, and joined means 61 provided at the proximal portion of the needle base 6, wherein a joint preventing means 90 which prevents the joining means 21 and the joined means 61 from being joined unintentionally before use, and allows joining to each other when in use is provided.
    • 为注射器提供针存储机构,其中针存储机构在使用前未被激活。 一种安全注射器,包括具有在远端的连接部分11和其近端的开口的注射筒1,具有注射针5的针组件B和固定到注射针5的近端的针座6 并且连接到连接部分11,在注射筒中液密地且可滑动地设置的垫圈2,连接到垫圈2的近端的柱塞3和设置在垫圈2的远端部分处的接合装置21或 柱塞3和设置在针座6的近端部分处的接合装置61,其中防止接合装置21和接合装置61在使用前意外接合的接合防止装置90,并且允许接合装置 在使用中提供。
    • 4. 发明授权
    • Plastic vessel containing an albumin preparation
    • 含有白蛋白制剂的塑料容器
    • US06326010B1
    • 2001-12-04
    • US09695215
    • 2000-10-25
    • Minoru SanoYoshihisa HamaToshiya KaiMasakazu Mameta
    • Minoru SanoYoshihisa HamaToshiya KaiMasakazu Mameta
    • A61J105
    • To provide a plastic vessel containing an albumin preparation which completely restrains formation of thermally denatured albumin, a plastic molded member in a cylindrical shape is extruded in a molten state into opened dies, one end of which is closed in the dies, and a vessel is molded by blowing a compressed gas into the molded member in the dies or by bringing inner portions of the dies into a vacuum state. While the vessel is still disposed in the dies, an albumin preparation is introduced from an opening portion into an inner portion of the vessel and, therefore, the albumin preparation can be filled into the vessel in a sterilized state without being brought into contact with the atmosphere. Then, an opening portion of the vessel filled with the albumin preparation is hermetically sealed at an internal temperature of the opening portion of about 40 to 70° C. Thus formation of thermally denatured albumin can be completely restrained.
    • 为了提供一种含有完全抑制热变性白蛋白形成的白蛋白制剂的塑料容器,将具有圆筒形状的塑料成型体以熔融状态挤出成开模,其一端在模具中封闭,容器为 通过将压缩气体吹入模具中的模制构件中或通过使模具的内部部分成为真空状态来模制。 当容器仍然设置在模具中时,白蛋白制剂从开口部分引入容器的内部,因此白蛋白制剂可以在灭菌状态下填充到容器中而不与其接触 大气层。 然后,填充有白蛋白制剂的容器的开口部分在约40-70℃的开口部分的内部温度下气密密封。因此可以完全抑制热变性白蛋白的形成。
    • 6. 发明授权
    • Prefilled syringe and production method for a barrel thereof
    • 预充注射器及其桶的生产方法
    • US07998120B2
    • 2011-08-16
    • US10762530
    • 2004-01-23
    • Minoru SanoYoshihisa Hama
    • Minoru SanoYoshihisa Hama
    • A61M5/00A61M5/31
    • B29C45/1603A61M5/3129B29C45/1642B29K2023/00B29K2023/086B29K2995/0067B29L2031/7544
    • A prefilled syringe composed of a barrel having a luer tip at one end and an open proximal end, the barrel having at least a three layer structure of an innermost layer, an outermost layer, both made of a polyolefin resin, and an intermediate layer made of a resin with a barrier property and sandwiched by the innermost layer and the outermost layer. The barrel is produced through the sequential steps of: (a) injecting a specific amount of a polyolefin resin inside a cavity; (b) injecting a specific amount of a resin excelling in barrier property; (c) injecting a specific amount of the polyolefin resin again; and (d) separating the luer tip surface and an injection unit by pushing off a valve pin provided inside a valve gate or an inner nozzle of the injection unit, which injects the resin excelling in barrier property, toward the direction of the luer tip surface as desired.
    • 一种预充式注射器,由具有在一端的鲁棒末端和开放的近端的筒体组成,所述筒体具有至少三层结构的最内层,最外层,均由聚烯烃树脂制成,中间层由 的具有阻挡性的树脂,并被最内层和最外层夹在中间。 通过以下顺序生产桶:(a)在空腔内注入特定量的聚烯烃树脂; (b)注入特定量的阻隔性优异的树脂; (c)再次注入特定量的聚烯烃树脂; 以及(d)通过将设置在注射单元的阀门或注射单元的内部喷嘴内的阀销推向鲁尔末端面的方向,从而分离鲁尔末端面和注射单元 如预期的。
    • 10. 发明申请
    • Saftey Syringe
    • Saftey注射器
    • US20100312197A1
    • 2010-12-09
    • US11991807
    • 2006-09-12
    • Minoru SanoYoshihisa Hama
    • Minoru SanoYoshihisa Hama
    • A61M5/315A61M5/34
    • A61M5/322A61M5/31501A61M5/31505A61M2005/31506A61M2005/31508A61M2005/3231A61M2005/5073
    • To provide a syringe with a needle storage mechanism in which the needle storage mechanism is not activated before use. A safety syringe including an injection barrel 1 having a connecting portion 11 at the distal end and an opening at the proximal end thereof, a needle assembly B having an injection needle 5 and a needle base 6 fixed to the proximal end of the injection needle 5 and being connected to the connecting portion 11, a gasket 2 provided liquid-tightly and slidably in the injection barrel, a plunger 3 being connected to the proximal end of the gasket 2 and joining means 21 provided at the distal portion of the gasket 2 or the plunger 3, and joined means 61 provided at the proximal portion of the needle base 6, wherein a joint preventing means 90 which prevents the joining means 21 and the joined means 61 from being joined unintentionally before use, and allows joining to each other when in use is provided.
    • 为注射器提供针存储机构,其中针存储机构在使用前未被激活。 一种安全注射器,包括具有在远端的连接部分11和其近端的开口的注射筒1,具有注射针5的针组件B和固定到注射针5的近端的针座6 并且连接到连接部分11,在注射筒中液密地且可滑动地设置的垫圈2,连接到垫圈2的近端的柱塞3和设置在垫圈2的远端部分处的接合装置21或 柱塞3和设置在针座6的近端部分处的接合装置61,其中防止接合装置21和接合装置61在使用前意外接合的接合防止装置90,并且允许接合装置 在使用中提供。