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1. 发明授权

US4963365A Controlled release dosage form 失效
标题翻译：控制释放剂型
公开(公告)号：US4963365A
公开(公告)日：1990-10-16
申请号：US267085
申请日：1988-11-04
申请人： Masayoshi Samejima , Kazuo Noda , Masao Kobayashi , Shigeyuki Ishikawa
发明人： Masayoshi Samejima , Kazuo Noda , Masao Kobayashi , Shigeyuki Ishikawa
IPC分类号： A61K9/22 , A61K9/50 , A61K9/54 , A61K9/62
CPC分类号： A61K9/5078
摘要： A controlled release dosage form which consists essentially of a core containing a medicament; an inner coating layer composed of ethylcellulose and a hydrophobic substance; and an outer coating layer containing a medicament are disclosed. Said dosage form shows rapid increase in blood concentration of the medicament and at the same time maintains the high level of the blood concentration over a prolonged period time.

2. 发明授权

US5202129A Process for micronizing slightly-soluble drug 失效
标题翻译：微溶解药物的方法
公开(公告)号：US5202129A
公开(公告)日：1993-04-13
申请号：US563091
申请日：1990-08-03
申请人： Masayoshi Samejima , Kazuo Noda , Masao Kobayashi , Takashi Osawa
发明人： Masayoshi Samejima , Kazuo Noda , Masao Kobayashi , Takashi Osawa
IPC分类号： A61J3/02 , A61K9/14 , A61K47/26
CPC分类号： A61K9/145
摘要： A process for micronizing a slightly-soluble drug characterized by subjecting a mixture of said drug and a sugar or sugar alcohol to high-speed stirring comminution or impact comminution in order to produce a micronized drug having an average diameter of less than about 2-3 mm. Also provided is a pharmaceutical formulation which comprises the micronized drug.

3. 发明授权

US5137733A Controlled release pharmaceutical preparation 失效
标题翻译：控制释放药物制剂
公开(公告)号：US5137733A
公开(公告)日：1992-08-11
申请号：US723031
申请日：1991-06-28
申请人： Kazuo Noda , Masao Kobayashi , Takashi Osawa , Shigeyuki Ishikawa
发明人： Kazuo Noda , Masao Kobayashi , Takashi Osawa , Shigeyuki Ishikawa
IPC分类号： A61K9/28 , A61K9/32 , A61K9/50 , A61K9/52 , A61K9/54 , A61K9/58 , A61K47/12 , A61K47/32
CPC分类号： A61K9/2846 , A61K9/5078 , Y10S514/963
摘要： A controlled release pharmaceutical preparation comprising a core containing a medicinal compound and a coating layer containing a water-repellent salt and a water-insoluble and slightly water-permeable acrylic polymer having trimethylammoniumethyl group. Said preparation releases a medicinal compound in a sigmoid type dissolution pattern irrespective of the PH of a dissolution medium.

4. 发明授权

US5068112A Controlled release pharmaceutical preparation and method for producing the same 失效
标题翻译：控制释放药物制备及其生产方法
公开(公告)号：US5068112A
公开(公告)日：1991-11-26
申请号：US329408
申请日：1989-03-24
申请人： Masayoshi Samejima , Kazuo Noda , Yoshiyuki Hirakawa , Hiroyuki Yoshino
发明人： Masayoshi Samejima , Kazuo Noda , Yoshiyuki Hirakawa , Hiroyuki Yoshino
IPC分类号： A61K9/22 , A61K9/28 , A61K9/32 , A61K9/36 , A61K9/50 , A61K9/52
CPC分类号： A61K9/5078 , A61K9/2866
摘要： Disclosed is a controlled release pharmaceutical preparation, comprising a core containing a pharmaceutically active ingredient, and a porous film of a hydrophobic polymeric substance or a hydrophobic polymeric substance and a hydrophilic polymeric substance, the core being coated with the porous film. Disclosed is also a method for producing the same. The controlled release pharmaceutical preparation of this invention posseses a desired dissolution rate by controlling the porosity of the porous film.

5. 发明授权

US5254347A Controlled release pharmaceutical preparation and method for producing the same 失效
标题翻译：控制释放药物制剂及其制备方法
公开(公告)号：US5254347A
公开(公告)日：1993-10-19
申请号：US729841
申请日：1991-07-12
申请人： Masayoshi Samejima , Kazuo Noda , Yoshiyuki Hirakawa , Hiroyuki Yoshino
发明人： Masayoshi Samejima , Kazuo Noda , Yoshiyuki Hirakawa , Hiroyuki Yoshino
IPC分类号： A61K9/28 , A61K9/50 , A61K9/16
CPC分类号： A61K9/2866 , A61K9/5078
摘要： Disclosed is a controlled release pharmaceutical preparation, comprising a core containing a pharmaceutically active ingredient, and a porous film of a hydrophobic polymeric substance or a hydrophobic polymeric substance and a hydrophilic polymeric substance, the core being coated with the porous film. Disclosed is also a method for producing the same. The controlled release pharmaceutical preparation of this invention posseses a desired dissolution rate by controlling the porosity of the porous film.
摘要翻译：公开了一种控释药物制剂，其包含含有药物活性成分的核心和疏水聚合物质或疏水性聚合物质和亲水性聚合物质的多孔膜，所述核心被多孔膜涂覆。也公开了其制造方法。通过控制多孔膜的孔隙率，本发明的控释药物制剂具有所需的溶出速率。

6. 发明授权

US5389380A Sustained release pharmaceutical preparation and process for preparing the same 失效
标题翻译：缓释药物制剂及其制备方法
公开(公告)号：US5389380A
公开(公告)日：1995-02-14
申请号：US120859
申请日：1993-08-31
申请人： Kazuo Noda , Masao Kobayashi , Takashi Osawa , Toru Maejima
发明人： Kazuo Noda , Masao Kobayashi , Takashi Osawa , Toru Maejima
IPC分类号： A61K9/22 , A61K9/42 , A61K9/50 , A61K9/52 , A61K47/02 , A61K47/44 , A61K9/16
CPC分类号： A61K9/5078
摘要： A sustained release pharmaceutical preparation comprising a carrier, an effective ingredient layer containing a medicinal compound and a heat-meltable material as a binder which is formed around said carrier and a coating layer containing a non-heat-meltable dissolution-controlling agent and a heat-meltable material as a binder which is formed around said effective ingredient layer and the process for preparing the same. According to the present invention, the formation of the effective ingredient layer and the formation of the coating layer can be successively carried out in the same apparatus without using any solvents or drying step in short hours to give a sustained release pharmaceutical preparation which can release a medicinal compound at a suitable dissolution rate according to the physical property of the medicinal compound.
摘要翻译：一种持续释放药物制剂，其包含载体，含有药用化合物的有效成分层和作为粘合剂的热熔性材料，其形成在所述载体周围;以及涂层，其含有不可热熔融的溶解控制剂和热作为在所述有效成分层周围形成的粘合剂的可熔性材料及其制备方法。根据本发明，可以在相同的装置中连续进行有效成分层的形成和涂层的形成，而不需要在短时间内使用任何溶剂或干燥步骤，得到缓释药物制剂根据药用化合物的物理性质，以合适的溶解速率进行药物化合物。

7. 发明授权

US5936920A Tracking method and device for use with an optical recording medium 失效
标题翻译：用于光记录介质的跟踪方法和装置
公开(公告)号：US5936920A
公开(公告)日：1999-08-10
申请号：US654914
申请日：1996-05-29
申请人： Kazuo Noda
发明人： Kazuo Noda
IPC分类号： G11B7/0033 , G11B7/09 , G11B7/095
CPC分类号： G11B7/0901 , G11B7/0903 , G11B7/0033
摘要： During recording of data on a recording medium, tracking is performed using auxiliary beams to refer to guide tracks as done in the conventional three-beam method. During reproduction of data from the recording medium, tracking is performed using a main beam to refer to a data pit recorded in a recording track in accordance with the push-pull method. In addition, there are provided two tracking control circuits based on the three-beam method and push-pull method, and the use of tracking control signals based on the three-beam and push-pull methods that are output from the two circuits is selected via a switch.
摘要翻译：在记录介质上记录数据期间，使用辅助光束进行跟踪，以参照常规三光束方法中的导轨。在从记录介质再现数据期间，使用主光束执行跟踪，以根据推挽方法指示记录在记录道中的数据凹坑。另外，提供了基于三光束法和推挽法的两个跟踪控制电路，并且选择基于从两个电路输出的三光束和推挽方法的跟踪控制信号的使用通过开关。

8. 发明授权

US5572495A Optical recording and reproducing system using servo control, switches and control circuitry 失效
标题翻译：使用伺服控制，开关和控制电路的光学记录和再现系统
公开(公告)号：US5572495A
公开(公告)日：1996-11-05
申请号：US350827
申请日：1994-12-07
申请人： Koichi Yamazaki , Kazuo Noda , Yonezo Furuya , Yasuyuki Kimura
发明人： Koichi Yamazaki , Kazuo Noda , Yonezo Furuya , Yasuyuki Kimura
IPC分类号： G11B7/085 , G11B7/09
CPC分类号： G11B7/0941
摘要： In a tracking or focusing servo control loop, there are provided a switch element for switch-controlling a tracking or focusing error signal, and a smoothing circuit for switching passage the error signal. An amount of detected reflection from an optical recording medium is monitored by a controller section, and the switching action of the switch element is ON/OFF-controlled by the controller section so as to maintain a servo loop gain at a predetermined standard. Thus, it is possible to maintain a constant servo loop gain without being influenced by variation in the laser light amount or difference in reflectivity characteristics of the recording layers of individual optical recording media, and constantly stable tracking servo control and/or focusing servo control can be performed.
摘要翻译：在跟踪或聚焦伺服控制回路中，提供了用于切换控制跟踪或聚焦误差信号的开关元件，以及用于切换通过误差信号的平滑电路。通过控制器部分监测来自光记录介质的检测反射量，并且由控制器部分对开关元件的开关动作进行ON / OFF控制，以使伺服环路增益保持在预定的标准。因此，可以在不受激光量的变化或各个光记录介质的记录层的反射率特性的差异的影响的情况下保持恒定的伺服环路增益，并且可以持续稳定的跟踪伺服控制和/或聚焦伺服控制被执行。

9. 发明授权

US5408451A Driving device for objective lens 失效
标题翻译：物镜驱动装置
公开(公告)号：US5408451A
公开(公告)日：1995-04-18
申请号：US38451
申请日：1993-03-29
申请人： Kazuo Noda , Eiichi Nakamura
发明人： Kazuo Noda , Eiichi Nakamura
IPC分类号： G11B7/085 , G11B7/09 , G11B7/00
CPC分类号： G11B7/0935 , G11B7/0932
摘要： To provide a driving device for an objective lens that has a high driving sensitivity and superior driving frequency characteristics.The present invention relates to a device for driving the objective lens (1) of an optical head that uses a device for recording information on an optical information recording medium, and for reproducing information therefrom, by irradiating a beam of light thereon while positioning and focusing the light with respect to an information track on the optical information recording medium. The device has a loose linkage member which supports an objective lens within a cylindrical member and comprises the cylindrical member (14 ) and a cylindrical hole portion (19 ) into which the cylindrical member is inserted so as to face the cylindrical hole with an air gap therebetween and with the axes thereof oriented vertically, and the driving force generated by a tracking coil (3 ) is transmitted through this loose linkage member to the objective lens.
摘要翻译：为了提供具有高驱动灵敏度和优异的驱动频率特性的物镜驱动装置。本发明涉及一种用于驱动光学头的物镜（1）的装置，该装置使用在光学信息记录介质上记录信息的装置，并且通过在定位和聚焦的同时照射其上的光束来再现信息相对于光学信息记录介质上的信息轨道的光。该装置具有松动的连接构件，其在圆柱形构件内支撑物镜，并且包括圆柱形构件（14）和圆柱形孔部分（19），圆柱形构件插入其中以与空气间隙并且其轴线垂直定向，并且由跟踪线圈（3）产生的驱动力通过该松动连接构件传递到物镜。

10. 发明授权

US5153863A Apparatus for optically recording and reproducing information 失效
标题翻译：用于光学记录和再现信息的装置
公开(公告)号：US5153863A
公开(公告)日：1992-10-06
申请号：US744645
申请日：1991-08-08
申请人： Kazuo Noda , Koichi Yamazaki
发明人： Kazuo Noda , Koichi Yamazaki
IPC分类号： G06K7/015 , G06K17/00 , G11B7/00 , G11B7/0033 , G11B7/004 , G11B7/09 , G11B7/13 , G11B7/135 , G11B7/14
CPC分类号： G11B7/14 , G11B7/0033 , G11B7/0938 , G11B7/13 , G11B7/135 , G11B7/0901 , G11B7/0903
摘要： An apparatus for optically recording and reproducing information in and from an optical information recording medium having a guide track. The apparatus uses an optical head having a diffraction grating, for recording and reproducing information. In recording information, a zero-order diffraction light beam from the diffraction grating is used for the information recording, and plus/minus first-order diffraction light beams from the diffraction grating are used for the tracking. In reproducing information, the zero-order diffraction light beam is used for the tracking, and higher- and odd-order diffraction light beams including at least plus/minus first-order diffraction light beams are used for information reproduction.
摘要翻译：一种用于在具有导轨的光学信息记录介质中光学记录和再现信息的装置。该装置使用具有衍射光栅的光学头，用于记录和再现信息。在记录信息中，使用来自衍射光栅的零级衍射光束进行信息记录，并且使用来自衍射光栅的正/负一级衍射光束进行跟踪。在再现信息中，使用零级衍射光束进行跟踪，并且使用包括至少正/负一级衍射光束的高次和次级衍射光束进行信息再现。

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