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1. 外观设计

USD320275S Medical applicator 失效
公开(公告)号：USD320275S
公开(公告)日：1991-09-24
申请号：US295159
申请日：1989-01-09
申请人： Masaru Wada , Junji Kimura , Zensho Kanda
设计人： Masaru Wada , Junji Kimura , Zensho Kanda

2. 发明授权

US07137958B2 Human spinal column measurement and display system 失效
标题翻译：人体脊柱测量和显示系统
公开(公告)号：US07137958B2
公开(公告)日：2006-11-21
申请号：US10487243
申请日：2002-04-18
申请人： Masaru Wada , Sadao Omata , Yoshikazu Kobayashi , Kenji Shirai
发明人： Masaru Wada , Sadao Omata , Yoshikazu Kobayashi , Kenji Shirai
IPC分类号： A61B5/103 , A61B5/117
CPC分类号： A61B5/4561 , A61B5/1077
摘要： According to a human spinal column measuring and displaying system of the invention, a probe is pinched between the second finger and the third finger of a measuring person, front ends of the fingers are moved from the first thoracic vertebra to the fifth lumbar vertebra of the spinal column of a measured subject, detaching amounts from reference positions in X, Y and Z directions are detected by three-dimensionally moving the front ends of the fingers. Based on measured data, positions of displaying the vertebrae in correspondence with positions of coordinates in X direction, Y direction and Z direction of the respective vertebrae are moved and a three-dimensional image of the spinal column of the measured subject is generated and the image of the spinal column is displayed on a display screen.
摘要翻译：根据本发明的人脊柱测量和显示系统，在测量人的第二手指和第三手指之间夹住探针，手指的前端从第一胸椎移动到第五腰椎的第五腰椎测量对象的脊柱，通过三维地移动手指的前端来检测从X，Y和Z方向上的参考位置的分离量。基于测量数据，移动与相应椎骨的X方向，Y方向和Z方向上的坐标位置相对应地显示椎骨的位置，并且生成测量对象的脊柱的三维图像，并且图像的脊柱显示在显示屏幕上。

3. 发明申请

US20050244941A1 Process for producing levodione 审中-公开
标题翻译：生产左氧氟沙星的方法
公开(公告)号：US20050244941A1
公开(公告)日：2005-11-03
申请号：US10505314
申请日：2003-02-15
申请人： Sakayu Shimizu , Masaru Wada
发明人： Sakayu Shimizu , Masaru Wada
IPC分类号： C12N15/09 , C12N9/02 , C12N15/53 , C12P7/26 , C12N1/18 , C12N15/74
CPC分类号： C12P7/26
摘要： An enone reductase characterized by a molecular mass of 61,300±5,000 Da; NADPH and NADH as co-factor; a temperature optimum of 55-60° C. at pH 7.4; a pH optimum of 4.5-8.5 and a substrate specificity on α,β-unsaturated ketones, especially derived from a yeast and a process for the preparation of levodione from ketoisophorane.
摘要翻译：特征在于分子量为61,300±5,000Da的烯酮还原酶; NADPH和NADH作为辅因子; 温度最适为55-60℃，pH 7.4; pH最适为4.5-8.5，对α，β-不饱和酮的底物特异性，特别是衍生自酵母，以及由酮二异戊酸制备左旋二酮的方法。

4. 发明授权

US06465228B1 Levodione reductase 有权
标题翻译：左旋去氧还原酶
公开(公告)号：US06465228B1
公开(公告)日：2002-10-15
申请号：US09495523
申请日：2000-01-31
申请人： Shigeru Nakamori , Sakayu Shimizu , Masaru Wada
发明人： Shigeru Nakamori , Sakayu Shimizu , Masaru Wada
IPC分类号： C12N902
CPC分类号： C12N9/0008 , C12P7/26 , C12P41/002
摘要： A levodione reductase having the following physical properties is provided: molecular weight: from about 142,000 to about 155,000±10,000 (consisting of four homologous subunits having a molecular weight of 36,000±5,000); co-factor: nicotinamide adenine dinucleotide (AND/NADH); substrate specificity: active on levodione; optimum temperature: about 15° C. to about 20° C. at pH 7.0; optimum pH: 7.5; and activator: K+, Cs+, Rb+, Na+ and NH4+. The levodione reductase according to the present invention produces actinol, an important intermediate for the production of zeaxanthin, from levodione. This enzyme may be produced from a microorganism belonging to the genus Corynebacterium, preferably the microorganism Corynebacterium aquaticum AKU 611 (FERM BP-6448) or a functional equivalent, subculture, mutant or variant thereof. Also provided is a process for producing the levodione reductase that includes cultivating a microorganism of the genus Corynebacterium in an aqueous medium under aerobic conditions, disrupting the cells of the microorganism and isolating and purifying the levodione reductase from the cell-free extract. A process for producing actinol from levodione is also provided that includes contacting levodione with levodione reductase in the presence of the reduced form of nicotinamide adenine dinucleotide or a cell-free extract of the microorganism, and then isolating the resulting actinol from the reaction mixture.
摘要翻译：提供了具有以下物理性质的左旋二酮还原酶：分子量：约142,000至约155,000±10,000（由分子量为36,000±5,000的四个同源亚基组成）; 辅因子：烟酰胺腺嘌呤二核苷酸（AND / NADH）; 底物特异性：对左旋多巴有活性; 最适温度：约15℃至约20℃，pH 7.0; 最适pH：7.5; 和活化剂：K +，Cs +，Rb +，Na +和NH4 +。根据本发明的左氧多糖还原酶从左旋二酮生产作为玉米黄质生产的重要中间体的肌动蛋白。该酶可以由属于棒状杆菌属的微生物，优选微生物棒状杆菌属水杨酸AKU 611（FERM BP-6448）或其功能等同的传代培养，突变体或变体产生。还提供了生产左旋体还原酶的方法，其包括在需氧条件下在水性介质中培养棒状杆菌属的微生物，破坏微生物的细胞并从无细胞提取物中分离和纯化左旋体还原酶。还提供了用于从左旋二酮生产锕系元素的方法，包括在还原形式的烟酰胺腺嘌呤二核苷酸或微生物的无细胞提取物的存在下将左旋多糖与左旋二酮还原酶接触，然后从反应混合物中分离得到的锕系元素。

5. 发明授权

US6072024A Production process of cross-linked polyaspartic acid resin 失效
标题翻译：交联聚天冬氨酸树脂的生产工艺
公开(公告)号：US6072024A
公开(公告)日：2000-06-06
申请号：US42942
申请日：1998-03-17
申请人： Yoshihiro Irizato , Makoto Sukegawa , Toshio Katoh , Hiroaki Tamatani , Akinori Nagatomo , Masaru Wada
发明人： Yoshihiro Irizato , Makoto Sukegawa , Toshio Katoh , Hiroaki Tamatani , Akinori Nagatomo , Masaru Wada
IPC分类号： C08G73/10 , C08G69/10
CPC分类号： C08G73/1092
摘要： A process is disclosed for producing with good productivity a cross-linked polyaspartic acid resin having biodegradability and high water absorbency. The process features inclusion of one of the following steps: (a) a polysuccinimide, which has been brought into a dispersed state by a dispersant, and a cross-linking agent are reacted to produce the cross-linked polyaspartic acid resin; (b) imide rings of a cross-linked polysuccinimide are subjected to a hydrolysis reaction while controlling a swelling degree of a resulting gel, whereby the cross-linked polyaspartic acid resin is produced; and (c) a gel of a cross-linked polysuccinimide, which has been obtained by reacting a cross-linking agent to a solution of a polysuccinimide in an organic solvent, is disintegrated to subject imide rings of the cross-linked polysuccinimide to a hydrolysis reaction, so that the cross-linked polyaspartic acid resin is produced. The process may also include one or both of the following steps as needed: (d) a gel of the cross-linked polyaspartic acid resin is washed with water and/or a water-miscible organic solvent; and (e) the polysuccinimide is produced using a basic amino acid as a cross-linking agent.
摘要翻译：公开了一种具有生物降解性和高吸水性的交联聚天冬氨酸树脂以高生产率生产的方法。该方法包括以下步骤之一：（a）已经通过分散剂进入分散状态的聚琥珀酰亚胺和交联剂反应生成交联聚天冬氨酸树脂; （b）交联聚琥珀酰亚胺的酰亚胺环进行水解反应同时控制所得凝胶的溶胀度，从而制得交联聚天冬氨酸树脂; 和（c）通过使交联剂与聚琥珀酰亚胺在有机溶剂中的溶液反应而获得的交联聚琥珀酰亚胺的凝胶被分解以使交联的聚琥珀酰亚胺的酰亚胺环进行水解反应，制成交联聚天冬氨酸树脂。该方法还可以根据需要包括以下步骤中的一种或两种：（d）用水和/或水混溶性有机溶剂洗涤交联聚天冬氨酸树脂的凝胶; 和（e）使用碱性氨基酸作为交联剂制备聚琥珀酰亚胺。

6. 发明授权

US5904554A Method for fabricating ohmic electrode and multi-layered structure for ohmic fabricating electrode 失效
标题翻译：欧姆电极制造欧姆电极和多层结构的方法
公开(公告)号：US5904554A
公开(公告)日：1999-05-18
申请号：US979862
申请日：1997-11-26
申请人： Chihiro Uchibori , Masanori Murakami , Akira Otsuki , Takeo Oku , Masaru Wada
发明人： Chihiro Uchibori , Masanori Murakami , Akira Otsuki , Takeo Oku , Masaru Wada
IPC分类号： H01L21/28 , H01L21/203 , H01L21/265 , H01L21/285 , H01L21/337 , H01L21/338 , H01L29/08 , H01L29/45
CPC分类号： H01L29/66924 , H01L21/28575 , H01L21/28581 , H01L29/0891 , H01L29/452 , H01L29/66878
摘要： An ohmic electrode for III-V compound semiconductors such as GaAs semiconductors which has practically satisfactory characteristics is disclosed. A non-single crystal InAs layer, Ni film, WSi film and W film are sequentially deposited on an n.sup.+ -type GaAs substrate by sputtering, etc. and subsequently patterned by lift-off, etc. to make a multi-layered structure for fabricating ohmic electrodes. The structure is then annealed first at, e.g. 300.degree. C. for 30 minutes and next at, e.g. 650.degree. C. for one second to fabricate an ohmic electrode.
摘要翻译：公开了具有实际令人满意的特性的诸如GaAs半导体的III-V族化合物半导体的欧姆电极。通过溅射等将非单晶InAs层，Ni膜，WSi膜和W膜依次沉积在n +型GaAs衬底上，随后通过剥离等进行图案化，以制造用于制造的多层结构欧姆电极。然后首先将结构退火，例如。 300℃，30分钟，然后在例如 650℃下制造欧姆电极1秒钟。

7. 发明授权

US5654483A Process for producing alkoxy-substituted triphenylamines 失效
标题翻译：制备烷氧基取代的三苯胺的方法
公开(公告)号：US5654483A
公开(公告)日：1997-08-05
申请号：US575091
申请日：1995-12-19
申请人： Chiyuki Kikuchi , Hiroshi Naruse , Masaru Wada , Teruyuki Nagata
发明人： Chiyuki Kikuchi , Hiroshi Naruse , Masaru Wada , Teruyuki Nagata
IPC分类号： C07C213/02 , C07C213/08 , C07C217/84 , C07C209/04 , C07C209/18
CPC分类号： C07C213/02 , C07C213/08 , C07C217/84
摘要： A process for producing an alkoxy-substituted tri-phenylamine comprising reacting an alkoxy-substituted cyclohexanone with a diphenylamine or an aniline, while forming said cyclohexanone in the same system from an alkoxy-substituted phenol by using said phenol as a hydrogen acceptor, in the presence of a hydrogen transfer catalyst and a catalytic amount of the alkoxy-substituted cyclohexanone corresponding to the alkoxy-substituted phenol used for the reaction, or after converting partially the alkoxy-substituted phenol to a catalytic amount of the alkoxy-substituted cyclohexanone under a hydrogen pressure in the presence of a hydrogen transfer catalyst, wherein a surface-supported catalyst is used as the hydrogen transfer catalyst.
摘要翻译：一种制备烷氧基取代的三苯胺的方法，包括使烷氧基取代的环己酮与二苯胺或苯胺反应，同时通过使用所述苯酚作为氢受体，从烷氧基取代的苯酚形成所述环己酮，同时在存在氢转移催化剂和催化量的对应于用于反应的烷氧基取代的苯酚的烷氧基取代的环己酮，或在氢气下部分将烷氧基取代的苯酚转化为催化量的烷氧基取代的环己酮之后在氢转移催化剂存在下的压力，其中使用表面负载的催化剂作为氢转移催化剂。

8. 发明授权

US5200729A Permanent magnet and magnetization apparatus for producing the permanent magnet 失效
标题翻译：用于生产永久磁铁的永久磁铁和磁化装置
公开(公告)号：US5200729A
公开(公告)日：1993-04-06
申请号：US479301
申请日：1990-02-07
申请人： Katsuji Soeda , Shuzo Otsuki , Masaru Wada
发明人： Katsuji Soeda , Shuzo Otsuki , Masaru Wada
IPC分类号： H01F7/02 , H01F13/00 , H02K1/27 , H02K15/03 , H02K41/03
CPC分类号： H01F13/003 , H01F7/021 , H02K1/2733 , H02K1/2793 , H02K15/03 , H02K41/03
摘要： Disclosed is a permanent magnet which is suitable for use for a field system of an electric motor or the like and which is constituted by a single piece of magnetic material in which S and N poles are alternately continuously formed through non-magnetic flux regions or weak magnetic flux regions interposed therebetween, and further disclosed is a magnetization apparatus for magnetizing such a permanent magnet. The magnetization apparatus comprises a first magnetic flux generation unit provided on one surface of a single piece of magnetic material for generating N-pole magnetic flux, a second magnetic flux generation unit provided adjacently to the first magnetic flux generation unit on the one surface for generating S-pole magnetic flux, and a third magnetic flux generation unit provided between the first and second magnetic flux generation unit on the one surface for passing therethrough part of magnetic flux generated by the first and second magnetic flux generation unit and for generating magnetic flux for canceling the magnetic flux passing through the third magnetic flux generation unit, whereby N and S poles are formed in domains of an object to be magnetized opposite to the first and second magnetic flux generation units and non-magnetic flux regions or weak magnetic flux regions are formed in domains of the object to be magnetized opposite to the third magnetic flux generation unit.
摘要翻译：公开了一种适用于电动机等的场系的永磁体，其由单片磁性材料构成，其中S和N极通过非磁通区域或弱磁性交替连续形成介于其间的磁通区域，并且还公开了一种用于磁化这种永磁体的磁化装置。磁化装置包括：第一磁通产生单元，设置在单个磁性材料的一个表面上，用于产生N极磁通;第二磁通量产生单元，设置在第一磁通量产生单元的一个表面上，用于产生 S极磁通和第一磁通产生单元，其设置在一个表面上的第一和第二磁通产生单元之间，用于通过由第一和第二磁通产生单元产生的磁通的部分，并产生用于抵消通过第三磁通产生单元的磁通量，从而在与第一和第二磁通量产生单元和非磁通区域或弱磁通量区域相对的待磁化对象的区域中形成N和S极形成在与第三磁通产生单元相对的待磁化对象的域中。

9. 发明授权

US5136086A Preparation process of aliphatic isocyanate 失效
标题翻译：脂肪族异氰酸酯的制备方法
公开(公告)号：US5136086A
公开(公告)日：1992-08-04
申请号：US819657
申请日：1992-01-13
申请人： Teruyuki Nagata , Masaru Wada , Hideki Mizuta
发明人： Teruyuki Nagata , Masaru Wada , Hideki Mizuta
IPC分类号： C07C263/10
CPC分类号： C07C263/10
摘要： This invention is an industrially efficient and improved process for the preparation of aliphatic polyisocyanates by using esters as the solvent for converting aliphatic polyamines to isocyanates.
摘要翻译：本发明是通过使用酯作为将脂族多胺转化为异氰酸酯的溶剂来制备脂肪族多异氰酸酯的工业上有效和改进的方法。

10. 发明授权

US4970323A Preparation process of N-substituted monochlorosuccinimides 失效
标题翻译： N-取代的一氯代琥珀酰亚胺的制备方法
公开(公告)号：US4970323A
公开(公告)日：1990-11-13
申请号：US370211
申请日：1989-06-22
申请人： Mihaya Matsukawa , Masaru Wada , Hiroshi Suizu , Masayuki Furuya , Teruyuki Nagata
发明人： Mihaya Matsukawa , Masaru Wada , Hiroshi Suizu , Masayuki Furuya , Teruyuki Nagata
IPC分类号： C07D207/10 , C07D207/40 , C07D207/416
CPC分类号： C07D207/416
摘要： N-substituted monochlorosuccinimides e.g., N-phenylmonochlorosuccinimide, can be prepared in a high yield by reacting a maleamic acid, e.g., N-phenylmaleamic acid, with phosgene in the presence of a catalyst, e.g., dimethylformamide.

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