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1. 发明授权

US07127094B1 Method of controlling data gathered at remote locations 失效
标题翻译：控制在偏远地区收集的数据的方法
公开(公告)号：US07127094B1
公开(公告)日：2006-10-24
申请号：US10336025
申请日：2003-01-02
申请人： Marek Elbaum , Adam Jacobs , Nikolai Kabelev , Sunguk Keem
发明人： Marek Elbaum , Adam Jacobs , Nikolai Kabelev , Sunguk Keem
IPC分类号： G06K9/00
CPC分类号： G06F19/321 , G06F19/00
摘要： Data corresponding to biological tissue or lesions imaged in a remote location are communicated automatically to a central location, where the data are analyzed using data and algorithms stored securely at the central location. A result of the analysis is communicated from the central location to the remote location. Payment to an entity associated with the central location is made for each image or set of images.
摘要翻译：对应于在远程位置成像的生物组织或病变的数据被自动传送到中心位置，其中使用安全地存储在中心位置的数据和算法对数据进行分析。分析结果从中心位置传递到远程位置。对于每个图像或一组图像，对与中心位置相关联的实体的支付。

2. 发明授权

US06201880B1 Method and apparatus for electronically imaging a tooth through transillumination by light 失效
标题翻译：通过光透过电子成像牙齿的方法和装置
公开(公告)号：US06201880B1
公开(公告)日：2001-03-13
申请号：US08778001
申请日：1996-12-31
申请人： Marek Elbaum , Michael Greenebaum , Adam Jacobs , Sunguk Keem , Allen H. Schneiderman , Theodore S. Shultz
发明人： Marek Elbaum , Michael Greenebaum , Adam Jacobs , Sunguk Keem , Allen H. Schneiderman , Theodore S. Shultz
IPC分类号： G06K900
CPC分类号： A61B1/24 , A61B5/0013 , A61B5/0088 , A61B5/7203 , A61B5/726 , A61B5/7425 , A61B2562/0238 , A61C19/04
摘要： A method and apparatus for imaging teeth includes illuminating a surface of a tooth and electronically imaging the tooth from a non-illuminated surface of the tooth with an electronic camera. Automatic control of the intensity of illumination is preferably provided to avoid saturation of the camera. The camera may include a charge-coupled-device and the resulting digital images are preferably enhanced by wavelet analysis. If a video camera is used, the images may be digitized and then enhanced. Current images of the tooth may be compared to prior images of the same tooth to monitor changes in the tooth over time. The images can be used to detect dental caries and other dental conditions. A handpiece for illuminating the tooth and receiving the light passing through the tooth for reception by the camera in a reproducible manner, is also described.
摘要翻译：用于成像牙齿的方法和装置包括用电子照相机照射牙齿的表面并用牙齿的未被照射的表面电子地成像牙齿。优选提供对照明强度的自动控制，以避免照相机的饱和。相机可以包括电荷耦合器件，并且所得数字图像优选地通过小波分析增强。如果使用摄像机，则图像可能被数字化，然后被增强。牙齿的当前图像可以与同一牙齿的先前图像进行比较，以监测牙齿随时间的变化。该图像可用于检测龋齿和其他牙齿状况。还描述了用于照亮牙齿并且接收通过牙齿的光以便以可再现的方式被照相机接收的手柄。

3. 发明授权

US06208749B1 Systems and methods for the multispectral imaging and characterization of skin tissue 失效
标题翻译：用于多光谱成像和皮肤组织表征的系统和方法
公开(公告)号：US06208749B1
公开(公告)日：2001-03-27
申请号：US09032450
申请日：1998-02-27
申请人： Dina Gutkowicz-Krusin , Marek Elbaum , Michael Greenebaum , Adam Jacobs
发明人： Dina Gutkowicz-Krusin , Marek Elbaum , Michael Greenebaum , Adam Jacobs
IPC分类号： G06K900
CPC分类号： A61B5/442 , A61B5/445 , G06F19/00
摘要： Systems and methods for the multispectral imaging of skin tissue enables automatic characterization of the condition of a region of interest of the skin, based on direct digital imaging of the region of interest or the digitization of color photographic slides of the region of interest, illuminated by appropriately filtered light. Preferably, a digital image at a low spectral band is automatically segmented and that segmented mask is used to segment the other images by a digital processor. Parameters related to the texture, asymmetry, blotchiness and border irregularities are also automatically estimated. The region of interest is automatically characterized by the digital processor, based on those parameters. The region of interest may include a skin lesion, in which case the present invention enables the characterization of the lesion as malignant or benign.
摘要翻译：用于皮肤组织的多光谱成像的系统和方法可以基于感兴趣区域的直接数字成像或感兴趣区域的彩色摄影载玻片的数字化，自动表征皮肤感兴趣区域的状况，由适当过滤光。优选地，在低频谱带处的数字图像被自动分段，并且该分割的掩模用于由数字处理器分割其它图像。还会自动估计与纹理，不对称，斑点和边界不规则相关的参数。基于这些参数，感兴趣的区域由数字处理器自动表征。感兴趣的区域可以包括皮肤损伤，在这种情况下，本发明能够将病变表征为恶性或良性。

4. 发明授权

US6081612A Systems and methods for the multispectral imaging and characterization of skin tissue 失效
标题翻译：用于多光谱成像和皮肤组织表征的系统和方法
公开(公告)号：US6081612A
公开(公告)日：2000-06-27
申请号：US31929
申请日：1998-02-27
申请人： Dina Gutkowicz-Krusin , Marek Elbaum , Michael Greenebaum , Adam Jacobs , Alexandru Bogdan
发明人： Dina Gutkowicz-Krusin , Marek Elbaum , Michael Greenebaum , Adam Jacobs , Alexandru Bogdan
IPC分类号： A61B5/103 , G06T5/00 , G06T7/00 , G06T7/40 , G06K9/00 , G06K9/36 , G01B9/02
CPC分类号： G06T7/408 , A61B5/0071 , A61B5/442 , A61B5/444 , A61B5/445 , A61B5/726 , G06T7/0012 , G06T7/402 , G06T2207/10064 , G06T2207/20064 , G06T2207/20148 , G06T2207/30088 , G06T2207/30096
摘要： Systems and methods for the multispectral imaging of skin tissue enables automatic characterization of the condition of a region of interest of the skin, based on direct digital imaging of the region of interest or the digitization of color photographic slides of the region of interest, illuminated by appropriately filtered light. Preferably, a digital image at a low spectral band is automatically segmented and that segmented mask is used to segment the other images by a digital processor. Parameters are estimated through wavelet maxima representations. Parameters related to the texture, asymmetry, blotchiness and border irregularities are also automatically estimated. The region of interest is automatically characterized by the digital processor, based on those parameters. The region of interest may include a skin lesion, in which case the present invention enables the characterization of the lesion as malignant or benign. The region of interest may also include wounds or burns.
摘要翻译：用于皮肤组织的多光谱成像的系统和方法可以基于感兴趣区域的直接数字成像或感兴趣区域的彩色摄影载玻片的数字化，自动表征皮肤感兴趣区域的状况，由适当过滤光。优选地，在低频谱带处的数字图像被自动分段，并且该分割的掩模用于由数字处理器分割其它图像。通过小波最大值表示来估计参数。还会自动估计与纹理，不对称，斑点和边界不规则相关的参数。基于这些参数，感兴趣的区域由数字处理器自动表征。感兴趣的区域可以包括皮肤损伤，在这种情况下，本发明能够将病变表征为恶性或良性。感兴趣的区域还可能包括伤口或烧伤。

5. 发明授权

US06307957B1 Multispectral imaging and characterization of biological tissue 失效
标题翻译：生物组织的多光谱成像和表征
公开(公告)号：US06307957B1
公开(公告)日：2001-10-23
申请号：US09604645
申请日：2000-06-27
申请人： Dina Gutkowicz-Krusin , Marek Elbaum , Michael Greenebaum , Adam Jacobs , Alexandru Bogdan
发明人： Dina Gutkowicz-Krusin , Marek Elbaum , Michael Greenebaum , Adam Jacobs , Alexandru Bogdan
IPC分类号： G06K900
CPC分类号： A61B1/00163 , A61B5/0059 , A61B5/0084 , A61B5/442 , A61B5/445 , A61B5/726 , G06K9/0014 , G06T7/0012
摘要： A light image is conveyed from a biological tissue through a flexible optical system to an image receiver, where it is converted to a form which may be entered into a computer. The computer segments the image by generating a segmentation mask defining the boundary of a region of interest in at least one spectral band, estimates at least one rotationally and translationally invariant statistical measure of coefficient distributions of the multiscale wavelet maxima representations of the digital images in at least one spectral band, characterizes the condition of the tissue based on the estimated values, and outputs the characterization of the condition of the tissue.
摘要翻译：光图像从生物组织通过柔性光学系统传送到图像接收器，在那里它被转换成可以输入计算机的形式。计算机通过在至少一个频谱带中生成定义感兴趣区域的边界的分割掩模来分割图像，估计数字图像的多尺度小波最大值表示中的系数分布的至少一个旋转和平移不变的统计量度至少一个光谱带，基于估计值表征组织的状况，并输出组织条件的表征。

6. 再颁专利

USRE35148E Frequency diversity for image enhancement 失效
公开(公告)号：USRE35148E
公开(公告)日：1996-01-23
申请号：US375798
申请日：1995-01-20
申请人： Frederic L. Lizzi , Marek Elbaum , Ernest J. Feleppa
发明人： Frederic L. Lizzi , Marek Elbaum , Ernest J. Feleppa
IPC分类号： G01S7/10 , G01S7/52 , G01S13/89 , G02B27/48 , H04N7/18
CPC分类号： G01S7/52046 , G01S13/89 , G01S7/10 , G01S7/5206 , G02B27/48 , G01S15/8954 , G01S7/52077
摘要： Methods for improving the availability of information derived from signals received from an object irradiated with coherent pulses of any form of radiation that exhibits a wave nature are disclosed. A method for reducing speckle derives separate component noncoherent signals from the received signals, and combines these separate noncoherent signals to form improved composite noncoherent signals. Weighting and processing of component signals can be applied as a function of time, frequency, and signal amplitude to optimize speckle reduction in all or a critical part of the signal by compensating for the range and frequency dependence of attenuation and the frequency dependence of scattering phenomena. In a method for enhancing resolution, separate component coherent signals are derived from the received signals, weighted and processed, and combined to form improved composite coherent signals; then noncoherent signals are derived from the improved composite coherent signals. In both methods, signals can be processed either in the analog or digital domains or in hybrid analog/digital domains. The apparatus for performing each method also is disclosed.

7. 发明授权

US4889398A Self referencing ambiguity free holography 失效
标题翻译：自我参考模糊自由全息术
公开(公告)号：US4889398A
公开(公告)日：1989-12-26
申请号：US177667
申请日：1988-04-05
申请人： Marek Elbaum , Dina Gutkowicz-Krusin , Jerzy Nowakowski
发明人： Marek Elbaum , Dina Gutkowicz-Krusin , Jerzy Nowakowski
IPC分类号： G03H1/00 , G03H3/00 , G03H5/00
CPC分类号： G03H1/16 , G03H1/0402 , G03H2001/0413 , G03H2001/2655 , G03H2222/35 , G03H2227/03
摘要： A method for self-referencing holography makes use of multiple object illuminations with different and non-uniform intensity of radiation to produce multiple holograms from the scattered radiation. Analysis of the multiple holograms provides an unambiguous image of the object.
摘要翻译：用于自参考全息术的方法利用具有不同和不均匀辐射强度的多个物体照明从散射辐射产生多个全息图。多重全息图的分析提供了对象的明确的图像。

8. 发明授权

US4561019A Frequency diversity for image enhancement 失效
标题翻译：用于图像增强的频率分集
公开(公告)号：US4561019A
公开(公告)日：1985-12-24
申请号：US494633
申请日：1983-05-16
申请人： Frederic L. Lizzi , Marek Elbaum , Ernest J. Feleppa
发明人： Frederic L. Lizzi , Marek Elbaum , Ernest J. Feleppa
IPC分类号： G01S7/10 , G01S7/52 , G01S13/89 , G02B27/48 , H04N7/18
CPC分类号： G01S7/52046 , G01S13/89 , G01S7/10 , G01S7/5206 , G02B27/48 , G01S15/8954 , G01S7/52077
摘要： Methods for improving the availability of information derived from signals received from an object irradiated with coherent pulses of any form of radiation that exhibits a wave nature are disclosed. A method for reducing speckle derives separate component noncoherent signals from the received signals, and combines these separate noncoherent signals to form improved composite noncoherent signals. Weighting and processing of component signals can be applied as a function of time, frequency, and signal amplitude to optimize speckle reduction in all or a critical part of the signal by compensating for the range and frequency dependence of attenuation and the frequency dependence of scattering phenomena. In a method for enhancing resolution, separate component coherent signals are derived from the received signals, weighted and processed, and combined to form improved composite coherent signals; then noncoherent signals are derived from the improved composite coherent signals. In both methods, signals can be processed either in the analog or digital domains or in hybrid analog/digital domains. The apparatus for performing each method also is disclosed.
摘要翻译：本发明公开了一种用于改善由从呈现波浪性的任何形式的辐射的相干脉冲照射的物体接收的信号得到的信息的可用性的方法。一种减少散斑的方法从接收到的信号中导出单独的分量非相干信号，并且将这些分离的非相干信号组合以形成改进的复合非相干信号。可以根据时间，频率和信号幅度来应用分量信号的加权和处理，以通过补偿衰减的范围和频率依赖性以及散射现象的频率依赖性来优化信号的全部或关键部分的散斑减少。在用于增强分辨率的方法中，从加权和处理的接收信号中导出分离的分量相干信号，并组合以形成改进的复合相干信号; 那么非相干信号从改进的复合相干信号导出。在这两种方法中，可以在模拟或数字域或混合模拟/数字域中处理信号。还公开了用于执行每种方法的装置。

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