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1. 发明授权

US09333147B2 Device for sealing a vessel and method of manufacturing a sealed vessel 有权
标题翻译：用于密封容器的装置和制造密封容器的方法
公开(公告)号：US09333147B2
公开(公告)日：2016-05-10
申请号：US13814915
申请日：2011-08-08
申请人： Andreas Schuetz , Makoto Kakiuchi , Seiji Shimazaki , Teruo Matsuda
发明人： Andreas Schuetz , Makoto Kakiuchi , Seiji Shimazaki , Teruo Matsuda
IPC分类号： A61J1/20 , A61M5/28 , A61J1/06 , B65B7/28 , B65B63/00 , B65B63/08 , B65B3/00 , A61M5/315 , A61M5/31
CPC分类号： A61J1/2096 , A61J1/065 , A61J1/2031 , A61J1/2093 , A61M5/284 , A61M5/31511 , A61M2005/3123 , B65B3/003 , B65B2220/14 , B65B2230/02
摘要： A device for sealing a vessel, in particular a cartridge (7) or a test-tube for accommodating a freeze-dried pharmaceutical product (S), wherein the vessel (1) comprises at its opening end (3) an opening edge (4) and an adjoining longitudinal portion (5) with an evenly formed inner cross section, including a front plunger (2) to be positioned inside the vessel (1) at the longitudinal portion (5), is characterized in that the front plunger (2) is configured to be positioned in the vessel (1) in a sealing state, in which the front plunger (2) is fully inserted in the vessel (1), or in an exchange state, in which the front plunger (2) is inserted partly in the vessel (1) and partly protrudes over the opening edge (4) of the vessel (1), wherein the front plunger (2) comprises sealing means that are configured to seal the inside of the vessel (1) against the outside when the front plunger (2) is positioned in the sealing state, and one or more communicating grooves (2i) that are configured to place the inside and outside of the vessel (1) in communication with each other when the front plunger (2) is positioned in the exchange state. Furthermore, a method of manufacturing a sealed vessel (1) is disclosed.
摘要翻译：一种用于密封容器的装置，特别是用于容纳冷冻干燥药物（S）的药筒（7）或试管，其中容器（1）在其开口端（3）处包括开口边缘（4））和具有均匀形成的内横截面的相邻的纵向部分（5），其包括在纵向部分（5）处定位在容器（1）内部的前柱塞（2），其特征在于，前柱塞（2））构造成在密封状态下定位在容器（1）中，其中前柱塞（2）完全插入容器（1）中，或者处于交换状态，其中前柱塞（2）是部分地插入容器（1）中并部分地突出在容器（1）的开口边缘（4）上，其中前柱塞（2）包括密封装置，其被构造成密封容器（1）的内部当前柱塞（2）位于密封状态时的外部，以及构造的一个或多个连通槽（2i）当前柱塞（2）位于交换状态时，将容器（1）的内部和外部放置在彼此连通。此外，公开了一种制造密封容器（1）的方法。

2. 发明申请

US20130197467A1 DEVICE FOR SEALING A VESSEL AND METHOD OF MANUFACTURING A SEALED VESSEL 有权
标题翻译：用于密封船舶的装置和制造密封船的方法
公开(公告)号：US20130197467A1
公开(公告)日：2013-08-01
申请号：US13814915
申请日：2011-08-08
申请人： Andreas Schuetz , Makoto Kakiuchi , Seiji Shimazaki , Teruo Matsuda
发明人： Andreas Schuetz , Makoto Kakiuchi , Seiji Shimazaki , Teruo Matsuda
IPC分类号： A61J1/20 , B65B63/08 , B65B63/00 , B65B7/28 , A61J1/06
CPC分类号： A61J1/2096 , A61J1/065 , A61J1/2031 , A61J1/2093 , A61M5/284 , A61M5/31511 , A61M2005/3123 , B65B3/003 , B65B2220/14 , B65B2230/02
摘要： A device for sealing a vessel, in particular a cartridge (7) or a test-tube for accommodating a freeze-dried pharmaceutical product (S), wherein the vessel (1) comprises at its opening end (3) an opening edge (4) and an adjoining longitudinal portion (5) with an evenly formed inner cross section, including a front plunger (2) to be positioned inside the vessel (1) at the longitudinal portion (5), is characterized in that the front plunger (2) is configured to be positioned in the vessel (1) in a sealing state, in which the front plunger (2) is fully inserted in the vessel (1), or in an exchange state, in which the front plunger (2) is inserted partly in the vessel (1) and partly protrudes over the opening edge (4) of the vessel (1), wherein the front plunger (2) comprises sealing means that are configured to seal the inside of the vessel (1) against the outside when the front plunger (2) is positioned in the sealing state, and one or more communicating grooves (2i) that are configured to place the inside and outside of the vessel (1) in communication with each other when the front plunger (2) is positioned in the exchange state. Furthermore, a method of manufacturing a sealed vessel (1) is disclosed.
摘要翻译：一种用于密封容器的装置，特别是用于容纳冷冻干燥药物（S）的药筒（7）或试管，其中容器（1）在其开口端（3）处包括开口边缘（4））和具有均匀形成的内横截面的相邻的纵向部分（5），其包括在纵向部分（5）处定位在容器（1）内部的前柱塞（2），其特征在于，前柱塞（2））构造成在密封状态下定位在容器（1）中，其中前柱塞（2）完全插入容器（1）中，或者处于交换状态，其中前柱塞（2）是部分地插入容器（1）中并部分地突出在容器（1）的开口边缘（4）上，其中前柱塞（2）包括密封装置，其被构造成密封容器（1）的内部当前柱塞（2）位于密封状态时的外部，以及构造的一个或多个连通槽（2i）当前柱塞（2）位于交换状态时，将容器（1）的内部和外部放置在彼此连通。此外，公开了一种制造密封容器（1）的方法。

3. 发明授权

US08517983B2 Dual chamber combined container-syringe 有权
标题翻译：双室组合容器注射器
公开(公告)号：US08517983B2
公开(公告)日：2013-08-27
申请号：US13276273
申请日：2011-10-18
申请人： Makoto Kakiuchi , Seiji Shimazaki , Teruo Matsuda
发明人： Makoto Kakiuchi , Seiji Shimazaki , Teruo Matsuda
IPC分类号： A61M37/00
CPC分类号： A61M5/284 , A61M5/31505 , A61M5/31515 , A61M5/31583 , A61M5/347 , A61M2005/3132 , A61M2005/31508
摘要： A dual chamber combined container-syringe includes: an outer casing having a bypass portion; a hub lure lock; a front stopper; a middle stopper that seals a pharmaceutical preparation together with the front stopper; an end stopper that seals a liquid medicine together with the middle stopper; a finger grip; and a plunger rod that is connected to the end stopper from the rear end side, wherein a female screw portion twisted around an axis is formed on an inner peripheral surface of the finger grip, and a first male screw portion, a tip of which comes into contact with a rear end of the female screw portion and can be screwed into the female portion, and a first guide plate are formed on an outer peripheral surface of the plunger rod when a part of the middle stopper enters the bypass portion.
摘要翻译：双室组合容器 - 注射器包括：具有旁路部分的外壳; 枢纽诱惑锁; 前挡块中间塞子，与前止动器一起密封药物制剂; 止血塞，其与中间塞子一起密封药液; 手指握力以及柱塞杆，其从后端侧连接到端部止动器，其中在手指的内周面上形成有围绕轴线扭转的阴螺纹部分，并且其顶端的第一阳螺纹部分与内螺纹部分的后端接触，并且可以拧入阴部，当中间止挡件的一部分进入旁路部分时，在柱塞杆的外周面上形成有第一引导板。

4. 发明授权

US4568769A Method for producing a mixture containing cycloalkanones and cycloalkanols 失效
标题翻译：制备含有环烷酮和环烷醇的混合物的方法
公开(公告)号：US4568769A
公开(公告)日：1986-02-04
申请号：US622865
申请日：1984-06-20
申请人： Akira Yashima , Teruo Matsuda , Tadao Sato , Mitsuaki Takahashi , Kiyomi Sakai
发明人： Akira Yashima , Teruo Matsuda , Tadao Sato , Mitsuaki Takahashi , Kiyomi Sakai
IPC分类号： C07C29/48 , C07C45/33 , C07C45/53 , C07C409/14
CPC分类号： C07C409/14 , C07C29/48 , C07C407/00 , C07C45/33 , C07C45/53 , C07C2101/14
摘要： Disclosed in a method for producing a mixture containing cycloalkanone and/or cycloalkanol which comprises oxidizing a cycloalkane with molecular oxygen to a cycloalkyl hydroperoxide represented by the formula (1): ##STR1## (wherein m represents an integer of 4.ltoreq.m.ltoreq.11) and decomposing the cycloalkyl hydroperoxide to obtain a mixture containing cycloalkanone and/or cycloalkanol, wherein the oxidation of the cycloalkane with molecular oxygen and/or the decomposition of the cycloalkyl hydroperoxide are carried out in the presence of a catalyst composition comprising at least one metallic salt represented by the formula (2):MX.sub.n (2)(wherein M represent Co, Mn, Cr or Fe, X represents an anionic ligand and n represents 2 or 3) and at least one compound represented by the formula (3): ##STR2## (wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently represent hydrogen or a lower alkyl group) and/or a catalyst composition comprising at least one metal complex represented by the formula (4): ##STR3## (wherein M represents Co, Mn, Cr or Fe, X represents an anionic ligand, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently represent hydrogen or a lower alkyl group, p is 1 or 2 and q is 0, 1 or 2).Advantages of the method are higher conversion of cycloalkyl hydroperoxide, higher yields of cycloalkanone and cycloalkanol and higher production ratio of cycloalkanone.
摘要翻译：本发明涉及制备含有环烷酮和/或环烷醇的混合物的方法，该方法包括用分子氧将环烷烃氧化为由式（1）表示的环烷基氢过氧化物：其中m表示4的整数， = m 11）并分解环烷基氢过氧化物以获得含有环烷酮和/或环烷醇的混合物，其中环烷烃与分子氧的氧化和/或环烷基氢过氧化物的分解在催化剂存在下进行包含至少一种由式（2）表示的金属盐的组合物：MXn（2）（其中M表示Co，Mn，Cr或Fe，X表示阴离子配体，n表示2或3）和至少一种由式（3）：其中R1，R2，R3和R4独立地表示氢或低级烷基）和/或包含至少一种由式（4）表示的金属络合物的催化剂组合物：（图） 4）（其中M表示Co，Mn，Cr或Fe，X表示阴离子配体，R1，R2，R3和R4独立地表示氢或低级烷基，p为1或2，q为0,1或2）。该方法的优点是环烷基氢过氧化物的转化率较高，环烷酮和环烷醇的产率较高，环烷酮的生产率较高。

5. 发明授权

US4236024A Process for producing diacetoxybutene 失效
标题翻译：生产二乙酰氧基丁烯的方法
公开(公告)号：US4236024A
公开(公告)日：1980-11-25
申请号：US15865
申请日：1979-02-27
申请人： Teruo Matsuda , Kuniyoshi Manabe
发明人： Teruo Matsuda , Kuniyoshi Manabe
IPC分类号： B01J23/40 , B01J27/02 , C07C67/05 , C07C67/055 , C07C69/16
CPC分类号： C07C67/055
摘要： Diacetoxybutene is prepared in a high yield with a high selectivity from butadiene, acetic acid and oxygen in the presence of a solid catalyst comprising sulfur, at least one noble metal selected from palladium, platinum and rhodium, and a carrier.
摘要翻译：在包含硫，选自钯，铂和铑的至少一种贵金属和载体的固体催化剂存在下，以高产率从丁二烯，乙酸和氧中选择性地制备二乙酰氧基丁烯。

6. 发明授权

US5011539A Descaling of jacket of glass-lined instruments 失效
标题翻译：玻璃衬里仪器外套除鳞
公开(公告)号：US5011539A
公开(公告)日：1991-04-30
申请号：US338000
申请日：1989-04-14
申请人： Teruo Matsuda , Masayoshi Miki , Hiromu Ochi
发明人： Teruo Matsuda , Masayoshi Miki , Hiromu Ochi
IPC分类号： C23G1/08 , C03C23/00 , C11D7/08
CPC分类号： C03C23/0075 , C11D7/08
摘要： A method for descaling the inside of a jacket of a glass-lined instrument by using a cleaning solution containing a detergent and an inhibitor is disclosed, wherein the amount of hydrogen permeated through the matrix of the instrument to the lining glass side is estimated by measuring a rate of hydrogen permeation through the jacket material or a test piece fitted to the circulation line of the cleaning solution and inserting the measured value into a previously established relationship between thickness of a steel plate and a rate of hydrogen permeation, and the concentrations of the detegent and the inhibitor in the cleaning solution, the descaling temperature or the descaling time is controlled so that the rate of hydrogen permeation through the matrix may not exceed 30 ml per m.sup.2 of the matrix during the descaling. A relatively large amount of scales can be rapidly and easily removed without causing breaking of the lining glass due to hydrogen permeation while minimizing corrosion of the matrix.

7. 发明授权

US4628587A Honing stone exchanger for use with superfinishing machines 失效
标题翻译：珩磨石材换热器与超精加工机一起使用
公开(公告)号：US4628587A
公开(公告)日：1986-12-16
申请号：US709173
申请日：1985-03-07
申请人： Kizo Kawaguchi , Teruo Matsuda
发明人： Kizo Kawaguchi , Teruo Matsuda
IPC分类号： B23Q3/155 , B24B33/10 , B24B45/00 , B24B33/00
CPC分类号： B23Q3/15513 , B24B33/10 , B24B45/003 , Y10T483/1707 , Y10T483/1729 , Y10T483/174
摘要： A honing stone exchanger for use with superfinishing machines wherein an annular workpiece is rotated on a main axis in a shoe centerless system by a drive unit, while a honing stone for superfinishing the outer peripheral surface of the annular workpiece is oscillated concentrically with the center of curvature of the outer peripheral surface by an oscillation unit, the honing stone exchanger being characterized in that it comprises a mechanism for stopping the oscillation shaft of the oscillation unit and positioning and fixing it at a predetermined position, a mechanism for moving a stone holder out of a processing position to a honing stone exchange position, and a mechanism for feeding a reserve honing stone to the stone holder moved to the honing stone exchange position.
摘要翻译：一种与超精加工机一起使用的珩磨石交换器，其中环形工件通过驱动单元在无鞋无心系统中在主轴线上旋转，而用于超精加工环形工件的外周表面的珩磨石与所述环形工件的外周面同心地摆动所述珩磨石交换器的特征在于，所述珩磨石交换器的特征在于，其包括用于停止所述振动单元的振动轴并将其定位并固定在预定位置的机构，用于将石头支架移出的机构处理位置到珩磨石交换位置的机构，以及将保留珩磨石供给到移动到珩磨石交换位置的石头保持架的机构。

8. 发明授权

US4605779A Method for the production of tiglic aldehyde 失效
标题翻译：生产噻唑醛的方法
公开(公告)号：US4605779A
公开(公告)日：1986-08-12
申请号：US758017
申请日：1985-07-24
申请人： Teruo Matsuda , Shinkichi Shimizu , Masaaki Iwasa
发明人： Teruo Matsuda , Shinkichi Shimizu , Masaaki Iwasa
IPC分类号： B01J27/00 , B01J27/02 , C07B61/00 , C07C45/00 , C07C45/62 , C07C45/67 , C07C47/21 , C07C67/00
CPC分类号： C07C45/62 , C07C45/67
摘要： A novel method for producing tiglic aldehyde from ethylacrolein by isomerization in the presence of a hydrogenating catalyst is disclosed. According to the invention, tiglic aldehyde can be prepared in a good yield.
摘要翻译：公开了一种在氢化催化剂存在下通过异构化由乙基丙烯醛生产噻唑醛的新方法。根据本发明，可以以良好的产率制备单体醛。

9. 发明授权

US5586975A Air and liquid tight container with a slidable gasket 失效
标题翻译：空气和液体密封容器，带有可滑动的垫片
公开(公告)号：US5586975A
公开(公告)日：1996-12-24
申请号：US365947
申请日：1994-12-29
申请人： Nobuo Tanaka , Seiji Otani , Hiroyuki Kawakita , Teruo Matsuda
发明人： Nobuo Tanaka , Seiji Otani , Hiroyuki Kawakita , Teruo Matsuda
IPC分类号： A61M5/315 , A61M37/00
CPC分类号： A61M5/31513 , A61M2005/31516 , A61M5/284 , A61M5/31596
摘要： An air and liquid-tight container is capable of storing different substances in different compartments sealingly separated by a front gasket having two separate parts that are independently slidable. A rear gasket is connectable to a push rod so as to function as a plunger, the front gasket being slidable in response to sliding of the rear gasket, thereby enabling the substance in the rear compartment to be introduced into the front compartment through a bypass. The front and rear gaskets are encased in the tubular body at a compressibility C (%) of 2% to 10%, with the product of the compressibility and the contact area (mm.sup.2) of the gaskets with the inside wall of the tubular wall falling within the range of 150 to 400.
摘要翻译：空气和液密容器能够将不同的物质存储在由具有独立可滑动的两个分离部分的前垫圈密封分隔的不同隔室中。后垫圈可连接到推杆以作为柱塞，前垫圈响应于后垫圈的滑动而可滑动，从而使得后隔室中的物质能够通过旁路被引入前隔室。前后垫圈的压缩率C（％）为2％至10％，压缩性和管状壁内壁的压缩性和接触面积（mm2）的乘积下降，在150到400的范围内。

10. 发明授权

US5891087A Mixing syringe 失效
标题翻译：混合注射器
公开(公告)号：US5891087A
公开(公告)日：1999-04-06
申请号：US818679
申请日：1997-03-14
申请人： Seiji Ohtani , Nobuo Tanaka , Katsuyuki Yokokawa , Teruo Matsuda
发明人： Seiji Ohtani , Nobuo Tanaka , Katsuyuki Yokokawa , Teruo Matsuda
IPC分类号： A61M5/28 , A61M5/31 , A61M5/315 , A61M37/00
CPC分类号： A61M5/284 , A61M5/31511 , A61M2005/3101 , A61M2005/3121 , A61M2005/3132 , A61M5/31501 , A61M5/31505
摘要： Behind a slidable end sealing member 3c, there is provided a liquid-absorbing element M which has a liquid-holding function so as to absorb and hold a liquid L flowing out from the end sealing member 3c when the end sealing member passes over a bypass portion 6. As this liquid-absorbent element M, such as a disk-like element D and a cylindrical element R, are typically impregnated with a water-holding and liquid-absorbing accelerator to enhance a leak preventing effect and with an antimicrobial active agent to enhance hygiene.
摘要翻译：在可滑动端部密封构件3c的后面，设置有液体吸收元件M，其具有液体保持功能，以便当端部密封构件通过旁路时吸收并保持从端部密封构件3c流出的液体L. 作为这样的液体吸收元件M，例如圆盘状元件D和圆柱形元件R，通常浸渍有吸水和吸液促进剂，以增强防漏效果，并具有抗微生物活性剂加强卫生。

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