专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO1995025764A1 DOUBLE-STRANDED DERIVATIVE OF POLYOXYETHYLENE-CONTAINING LIPID 审中-公开
标题翻译：含有聚氧乙烯的脂肪的双重衍生衍生物
公开(公告)号：WO1995025764A1
公开(公告)日：1995-09-28
申请号：PCT/JP1995000535
申请日：1995-03-23
申请人： MEIJI SEIKA KABUSHIKI KAISHA , WATANABE, Hiroshi , TANIGUCHI, Kumi , UDAGAWA, Chikako , ANDO, Takashi , NAKABAYASHI, Satoru
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C08G65/32
CPC分类号： C08G65/3322 , A61K9/1272 , A61K47/14 , A61K47/18 , A61K47/183 , A61K47/60 , C08G65/329
摘要： A compound represented by general formula (I). It is useful as a particulate drug carrier, because it can efficiently evade the reticuloendothelial system and can remain in the blood for long.
摘要翻译：由通式（I）表示的化合物。它作为颗粒药物载体是有用的，因为它可以有效地避开网状内皮系统并长时间保留在血液中。

2. 发明申请

WO1995018130A1 TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES 审中-公开
标题翻译：三氯苯并苯并噻唑衍生物
公开(公告)号：WO1995018130A1
公开(公告)日：1995-07-06
申请号：PCT/JP1994002282
申请日：1994-12-28
申请人： MEIJI SEIKA KABUSHIKI KAISHA , OHTSUKA, Yasuo , SHISHIKURA, Takashi , OGINO, Hiroko , FUSHIHARA, Kenichi , KAWAGUCHI, Mami , TSUTSUMI, Seiji , IMAI, Megumi , SHITO, Keiko , TSUCHIYA, Koji , TANAKA, Junko , IWASAKI, Takako , HOSHIKO, Shigeru , TSURUOKA, Takashi
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07D487/04
CPC分类号： C07D487/04 , C07D249/04 , C07D513/04 , Y02P20/55
摘要： Tricyclic benzazepine and benzothiazepine derivatives represented by general formula (I) and pharmacologically acceptable salts thereof, wherein Z represents CO, -CR R - or -S(O)n; R represents hydrogen, alkyl, phenylalkyl or a triazole-protective group; and R to R represent each hydrogen, alkyl, alkenyl, alkoxy, amino, oxime or hydroxy. The compounds have an antiallergic activity and hence are useful for treating and preventing allergic diseases.
摘要翻译：由通式（I）表示的三环苯并吖庚因衍生物和苯并硫氮杂衍生物及其药理学上可接受的盐，其中Z表示CO，-CR 6 R 7或-S（O）n; R代表氢，烷基，苯基烷基或三唑保护基; R 1至R 5各自代表氢，烷基，烯基，烷氧基，氨基，肟或羟基。该化合物具有抗过敏活性，因此可用于治疗和预防过敏性疾病。

3. 发明申请

WO1995005171A1 ANTI-MRSA COMPOSITION 审中-公开
标题翻译：抗MRSA组合物
公开(公告)号：WO1995005171A1
公开(公告)日：1995-02-23
申请号：PCT/JP1994001353
申请日：1994-08-16
申请人： MEIJI SEIKA KABUSHIKI KAISHA , BIOMATERIAL CO., LTD. , YONETA, Toshio , FUJII, Naoyuki , OOISHI, Maki , IINUMA, Katsuharu , SATO, Atsuyuki , YASUDA, Kimiaki
发明人： MEIJI SEIKA KABUSHIKI KAISHA , BIOMATERIAL CO., LTD.
IPC分类号： A61K31/415
CPC分类号： D21H21/36 , A01N43/50 , A61K31/415 , A61L31/16 , A61L2300/204 , A61L2300/404 , D06M13/352 , D06M16/00 , D06N3/0059 , A01N25/34 , A01N2300/00
摘要： An anti-methicillin-resistant Staphylococcus aureus (MRSA) composition containing an imidazole derivative represented by general formula (I), wherein R , R , R and R represent each independently hydrogen or halogen. Since the above compound has an anti-MRSA activity, it can provide a composition efficacious in preventing infection with MRSA and a textile product bearing the composition.
摘要翻译：含有由通式（I）表示的咪唑衍生物的抗甲氧西林抗性金黄色葡萄球菌（MRSA）组合物，其中R 1，R 2，R 3和R 4各自独立地表示氢或卤素。由于上述化合物具有抗MRSA活性，因此可以提供有效预防感染MRSA的组合物和具有该组合物的纺织品。

4. 发明申请

WO1994001392A1 (-)-RITODRINE 审中-公开
标题翻译：（ - ） - 利托君
公开(公告)号：WO1994001392A1
公开(公告)日：1994-01-20
申请号：PCT/JP1993000896
申请日：1993-06-30
申请人： MEIJI SEIKA KABUSHIKI KAISHA , YAMAZAKI, Naoki , FUKUDA, Yoshimasa , SHIBAZAKI, Yoshiaki , NIIZATO, Tetsutarou , KOSUGI, Isao , YOSHIOKA, Shin
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07C215/60
CPC分类号： C07C215/60 , A61K31/135
摘要： (-)-Ritodrine, i.e. (-)-erythro-1-(p-hydroxyphenyl)-2-[2-(p-hydroxyphenyl)ethylamino]-1-pr opanol, which is substantially free from the (+)-isomer, or a salt thereof. This compound has a potent effect of inhibiting uterine contraction as compared with (+/-)-ritodrine and (+)-ritodrine and a toxicity comparable to those of the other ritodrines, and hence is usable as a highly safe remedy for threatened premature birth and abortion and a remedy for dysmenorrhea.
摘要翻译：（ - ） - 基本上不含（+） - 异构体的（ - ） - 赤 - 1-（对羟基苯基）-2- [2-（对羟基苯基）乙基氨基] ，或其盐。与（+/-） - 利培酮和（+） - 利培酮相比，该化合物具有抑制子宫收缩的有效作用，其毒性与其他孕妇相当，因此可用作威胁性早产的高度安全补救措施堕胎和痛经补救。

5. 发明申请

WO1997021718A1 CRYSTALLINE 1-KESTOSE AND PROCESS FOR PREPARING THE SAME 审中-公开
标题翻译：晶体1-酮酶及其制备方法
公开(公告)号：WO1997021718A1
公开(公告)日：1997-06-19
申请号：PCT/JP1996003618
申请日：1996-12-11
申请人： MEIJI SEIKA KABUSHIKI KAISHA , NISHIZAWA, Koji , MATSUMOTO, Hitoshi , NAKAMURA, Hirofumi , KAWAKAMI, Takashi , NAKADA, Yuko , HIRAYAMA, Masao , ADACHI, Takashi
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07H03/06
CPC分类号： C07H3/06 , C12P19/18 , C30B7/00
摘要： A process for preparing crystalline 1-kestose which enables crystalline 1-kestose in large fine granulated sugar form to be prepared with high recovery. The process comprises concentrating a high-purity 1-kestose solution to a Brix of not less than 75, depositing crystallites serving as a mother nucleus by adding seed crystals or by concentration under reduced pressure, and repeating at least twice the step of growing crystals by concentration under reduced pressure and the step of redissolving crystallites produced in the concentrate. Alternatively, the process comprises concentrating a high-purity 1-kestose solution to a Brix of not less than 80, growing crystals after addition of seed crystals or induction of crystallization, and repeating at least twice the step of lowering the temperature by 5 to 20 DEG C below the temperature in the previous step and the step of growing crystals growth by allowing the concentrate to stand at the above temperature. An enzyme capable of efficiently converting sucrose to 1-kestose is also disclosed.
摘要翻译：制备结晶1-kestose的方法，其使得能够以高回收率制备大细粒状糖形式的结晶1-kestose。该方法包括将高纯度1-kestose溶液浓缩至不小于75的白利糖度，通过加入晶种或通过减压浓缩沉积作为母核的微晶，并重复至少两次生长晶体的步骤在减压下的浓度和再浓缩浓缩物中产生的微晶的步骤。或者，该方法包括将高纯度1-kestose溶液浓缩至不低于80的白利糖度，加入晶种后生长晶体或诱导结晶，并重复至少两次将温度降低5至20的步骤 ℃以下，通过使浓缩物在上述温度下放置，生长晶体生长步骤。还公开了能够有效地将蔗糖转化成1-kestose的酶。

6. 发明申请

WO1997000258A1 TRICYCLIC BENZAZEPINE COMPOUNDS 审中-公开
标题翻译：三氯苯甲腈化合物
公开(公告)号：WO1997000258A1
公开(公告)日：1997-01-03
申请号：PCT/JP1996001628
申请日：1996-06-14
申请人： MEIJI SEIKA KABUSHIKI KAISHA , OHTSUKA, Yasuo , NISHIZUKA, Toshio , SHIOKAWA, Sohjiro , TSUTSUMI, Seiji , FUSIHARA, Kenichi , KAWAGUCHI, Mami , IMAI, Megumi , SHITO, Keiko , TSUCHIYA, Koji , IWASAKI, Takako , OGINO, Hiroko , SHISHIKURA, Takashi
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07D487/04
CPC分类号： C07D405/06 , C07D249/04 , C07D487/04 , C07D491/14 , Y02P20/55
摘要： Tricyclic benzazepine compounds represented by general formula (I) and pharmacologically acceptable salts thereof. Because of having antiallergic effects, these compounds are useful in the treatment and prevention of bronchial asthma, eczema, urticaria, allergic gastrointestinal disorders, allergic rhinitis, allergic conjunctivitis, etc., wherein R represents hydrogen, substituted C1-6 alkyl or a protecting group; R , R , R and R represent each hydrogen, hydroxy, substituted C1-4 alkyl, substituted C2-12 alkenyl, substituted C1-12 alkoxy or substituted amino.
摘要翻译：由通式（I）表示的三环苯并氮杂化合物及其药理学上可接受的盐。由于具有抗过敏作用，这些化合物可用于治疗和预防支气管哮喘，湿疹，荨麻疹，过敏性胃肠疾病，过敏性鼻炎，过敏性结膜炎等，其中R表示氢，取代的C 1-6烷基或保护基 ; R 1，R 2，R 3和R 4分别表示氢，羟基，取代的C 1-4烷基，取代的C 12-12烯基，取代的C 1-12烷氧基或取代的氨基。

7. 发明申请

WO1996011180A1 'gamma'-DIKETONE COMPOUND HAVING PLATELET AGGREGATION INHIBITING EFFECT 审中-公开
标题翻译：具有平板电泳抑制效应的γ-二酮化合物
公开(公告)号：WO1996011180A1
公开(公告)日：1996-04-18
申请号：PCT/JP1995002057
申请日：1995-10-06
申请人： MEIJI SEIKA KABUSHIKI KAISHA , MIURA, Tomoaki , SHITARA, Eiki , OHUCHI, Shokichi , KATANO, Kiyoaki
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07C225/16
CPC分类号： C07D495/04 , C07C257/18
摘要： A gamma -diketone compound represented by general formula (I) and having a platelet aggregation inhibiting effect, a pharmacologically acceptable salt thereof, and a solvate thereof, wherein B represents -Z(CH2)q-COOR ; and A represents formula (II) or (III).
摘要翻译：由通式（I）表示并具有血小板聚集抑制作用的γ-二酮化合物，其药理学上可接受的盐及其溶剂合物，其中B表示-Z（CH2）q -OROR7; A表示式（II）或（III）。

8. 发明申请

WO1997030040A1 NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME 审中-公开
标题翻译：新的四氢呋喃酮衍生物及其制备方法
公开(公告)号：WO1997030040A1
公开(公告)日：1997-08-21
申请号：PCT/JP1997000451
申请日：1997-02-19
申请人： MEIJI SEIKA KABUSHIKI KAISHA , KURIHARA, Kenichi , SHINEI, Rie , TANABE, Kiyoshi , YAMAMOTO, Yasuo , AJITO, Keiichi , MIYAJIMA, Kaori , TABATA, Yuji , YASUDA, Shohei , TATSUTA, Kuniaki , OKONOGI, Tsuneo
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07D307/92
CPC分类号： C07D307/92 , C07D407/12 , C07D407/14 , C07D409/12 , C07D417/12
摘要： Compounds represented by general formula (I) and pharmaceutically acceptable salts thereof, which have progesterone receptor binding inhibitory activities and so are used as remedies and preventives for diseases in which progesterone participates, more particularly, as anticancer agents against mammary and ovarian cancers, remedies for uterine myoma, endometriosis, meningioma and myeloma, abortifacient, peroral contraceptive, and remedies and preventives for osteoporosis and climacteric disturbance, wherein R and R represent each hydroxy, alkyloxy, alkenyloxy, alkynyloxy, cycloalkyloxy, alkoxyalkyloxy, oxygenous cycloalkyloxy, aralkyloxy, alkylcarbonyloxy, alkenylcarbonyloxy, alkynylcarbonyloxy, cycloalkylcarbonyloxy, alkoxycarbonyloxy, aryloxycarbonyloxy, aralkylcarbonyloxy, aromatic acyloxy, heteroaromatic acyloxy, saturated heterocyclic carbonyloxy, alkylsulfonyloxy, aromatic sulfonyloxy, alkylcarbamoyloxy, or aromatic carbamoyloxy, the R optionally representing hydrogen alkyl, alkenyl, or alkynyl; and R , R , and R represent each independently hydrogen, alkyl, or alkenyl.
摘要翻译：具有孕酮受体结合抑制活性的由通式（I）表示的化合物及其药学上可接受的盐等用作对孕激素参与的疾病的补救措施和预防药物，更特别地，作为抗乳腺癌和卵巢癌的抗癌剂，子宫肌瘤，子宫内膜异位症，脑膜瘤和骨髓瘤，流产，口服避孕药，以及骨质疏松症和更年期障碍的治疗和预防药物，其中R 1和R 2代表各羟基，烷氧基，烯氧基，炔氧基，环烷氧基，烷氧基烷氧基，芳烷氧基，烷基羰基氧基，链烯基羰基氧基，炔基羰基氧基，环烷基羰基氧基，烷氧基羰基氧基，芳氧基羰基氧基，芳烷基羰基氧基，芳香族酰氧基，杂芳基酰氧基，饱和杂环羰基氧基，烷基磺酰氧基，芳香族磺酰氧基，烷基氨基甲酰氧基或芳族氨基甲酰氧基，R 1任选代表氢烷基，烯基或炔基; R 3，R 4和R 5各自独立地表示氢，烷基或链烯基。

9. 发明申请

WO1996002503A1 NOVEL COMPOUND HAVING PLATELET AGGREGATION INHIBITOR EFFECT 审中-公开
标题翻译：具有平板聚集抑制剂效果的新型化合物
公开(公告)号：WO1996002503A1
公开(公告)日：1996-02-01
申请号：PCT/JP1995001419
申请日：1995-07-17
申请人： MEIJI SEIKA KABUSHIKI KAISHA , KATANO, Kiyoaki , OHUCHI, Shokichi , MIURA, Tomoaki , SHITARA, Eiki , SHIMIZU, Masaro , YAEGASHI, Kazue , OHKURA, Naoto , ISOMURA, Yasuko , IIDA, Hiroyuki , ISHIKAWA, Midori , ASAI, Kenji , HATSUSHIBA, Emiko
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07D211/58
CPC分类号： C07D401/04 , C07D211/58 , C07D401/14 , C07D405/14
摘要： A compound represented by general formula (I) and having a platelet aggregation inhibitor effect and pharmacologically acceptable salt and solvate thereof, wherein A, B and C represent each CH2 or C=O; X and Y are different from each other and represent CH or N; D represents -(CH2)k- or -(CH2)m-CO-, wherein k represents an integer of 1 to 4, and m represents an integer of 0 to 3; E represents group (II) or (III), wherein n represents an integer of 1 to 3, Z represents -W-(CH2)p-COOR , W represents -O- or a bond, p represents an integer of 1 to 4, and R represents hydrogen, lower alkyl or an ester residue eliminable under physiological conditions; R represents hydrogen or lower alkyl; and R represents hydrogen or lower alkyl.
摘要翻译：由通式（I）表示并具有血小板聚集抑制剂作用的化合物及其药理学上可接受的盐和溶剂合物，其中A，B和C表示每个CH 2或C = O; X和Y彼此不同，表示CH或N; D表示 - （CH 2）k - 或 - （CH 2）m -CO-，其中k表示1〜4的整数，m表示0〜3的整数。 E表示式（II）或（III），其中n表示1〜3的整数，Z表示-W-（CH 2）p -COOR 3，W表示-O-或键，p表示 1至4，R 3表示在生理条件下可消除的氢，低级烷基或酯残基; R 1表示氢或低级烷基; R 2表示氢或低级烷基。

10. 发明申请

WO1995007912A1 NOVEL CEPHEM DERIVATIVE 审中-公开
标题翻译：新CEPHEM DERIVATIVE
公开(公告)号：WO1995007912A1
公开(公告)日：1995-03-23
申请号：PCT/JP1994001529
申请日：1994-09-16
申请人： MEIJI SEIKA KABUSHIKI KAISHA , ATSUMI, Kunio , UMEMURA, Eijiro , KANO, Yuko , SHIOKAWA, Sohjiro , KUDO, Toshiaki , TSUSHIMA, Masaki , IWAMATSU, Katsuyoshi , TAMURA, Atsushi , SHIBAHARA, Seiji
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07D519/00
CPC分类号： C07D501/00
摘要： A compound represented by general formula (I), i.e., a cephem derivative having an (un)substituted imidazo[5,1-b]thiazolium-6-yl group at the 3-position of the ring, wherein X represents CH or N; R represents H, alkyl, alkenyl, etc.; and R , R , R and R represent each H, alkyl, carbamoyl, amino, etc. This compound has an excellent antibacterial activity and is useful as a remedy for various types of microbism.
摘要翻译：由通式（I）表示的化合物，即在环的3位具有（未）取代的咪唑并[5,1-b]噻唑鎓-6-基的头孢烯衍生物，其中X表示CH或N ; R 1表示H，烷基，烯基等; R 2，R 3，R 4和R 5分别表示H，烷基，氨基甲酰基，氨基等。该化合物具有优异的抗菌活性，可用于各种微生物的补救。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式