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1. 发明申请

WO2010131676A1 PROCESS FOR PRODUCING PYRIPYROPENE DERIVATIVE 审中-公开
标题翻译：生产吡啶衍生物的方法
公开(公告)号：WO2010131676A1
公开(公告)日：2010-11-18
申请号：PCT/JP2010058040
申请日：2010-05-12
申请人： MEIJI SEIKA KAISHA , FUKUDA YOSHIMASA , ANDO TAKASHI , GOTO KIMIHIKO , NAKANISHI NOZOMU , WATANABE TAKASHI , KURIHARA KENICHI , MINOWA NOBUTO , MITOMI MASAAKI
发明人： FUKUDA YOSHIMASA , ANDO TAKASHI , GOTO KIMIHIKO , NAKANISHI NOZOMU , WATANABE TAKASHI , KURIHARA KENICHI , MINOWA NOBUTO , MITOMI MASAAKI
IPC分类号： C07D405/04 , C07B61/00
CPC分类号： C07D493/04
摘要： A process for efficiently producing a pyripyropene derivative having acyloxy groups in the 1- and 11- positions and a hydroxy group in the 7-position. The process comprises a step in which the hydroxy groups in the 1- and 11-positions of the compound represented by formula (B1) are selectively acylated with an acylating agent in the presence or absence of a base in one to three stages.
摘要翻译：一种在1-位和11位有效生产具有酰氧基的吡啶并苯衍生物和7-位羟基的方法。该方法包括在碱存在或不存在下，在一到三个阶段中，用酰化剂选择性地酰化由式（B1）表示的化合物的1位和11位中的羟基。

2. 发明申请

WO1997030040A1 NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME 审中-公开
标题翻译：新的四氢呋喃酮衍生物及其制备方法
公开(公告)号：WO1997030040A1
公开(公告)日：1997-08-21
申请号：PCT/JP1997000451
申请日：1997-02-19
申请人： MEIJI SEIKA KABUSHIKI KAISHA , KURIHARA, Kenichi , SHINEI, Rie , TANABE, Kiyoshi , YAMAMOTO, Yasuo , AJITO, Keiichi , MIYAJIMA, Kaori , TABATA, Yuji , YASUDA, Shohei , TATSUTA, Kuniaki , OKONOGI, Tsuneo
发明人： MEIJI SEIKA KABUSHIKI KAISHA
IPC分类号： C07D307/92
CPC分类号： C07D307/92 , C07D407/12 , C07D407/14 , C07D409/12 , C07D417/12
摘要： Compounds represented by general formula (I) and pharmaceutically acceptable salts thereof, which have progesterone receptor binding inhibitory activities and so are used as remedies and preventives for diseases in which progesterone participates, more particularly, as anticancer agents against mammary and ovarian cancers, remedies for uterine myoma, endometriosis, meningioma and myeloma, abortifacient, peroral contraceptive, and remedies and preventives for osteoporosis and climacteric disturbance, wherein R and R represent each hydroxy, alkyloxy, alkenyloxy, alkynyloxy, cycloalkyloxy, alkoxyalkyloxy, oxygenous cycloalkyloxy, aralkyloxy, alkylcarbonyloxy, alkenylcarbonyloxy, alkynylcarbonyloxy, cycloalkylcarbonyloxy, alkoxycarbonyloxy, aryloxycarbonyloxy, aralkylcarbonyloxy, aromatic acyloxy, heteroaromatic acyloxy, saturated heterocyclic carbonyloxy, alkylsulfonyloxy, aromatic sulfonyloxy, alkylcarbamoyloxy, or aromatic carbamoyloxy, the R optionally representing hydrogen alkyl, alkenyl, or alkynyl; and R , R , and R represent each independently hydrogen, alkyl, or alkenyl.
摘要翻译：具有孕酮受体结合抑制活性的由通式（I）表示的化合物及其药学上可接受的盐等用作对孕激素参与的疾病的补救措施和预防药物，更特别地，作为抗乳腺癌和卵巢癌的抗癌剂，子宫肌瘤，子宫内膜异位症，脑膜瘤和骨髓瘤，流产，口服避孕药，以及骨质疏松症和更年期障碍的治疗和预防药物，其中R 1和R 2代表各羟基，烷氧基，烯氧基，炔氧基，环烷氧基，烷氧基烷氧基，芳烷氧基，烷基羰基氧基，链烯基羰基氧基，炔基羰基氧基，环烷基羰基氧基，烷氧基羰基氧基，芳氧基羰基氧基，芳烷基羰基氧基，芳香族酰氧基，杂芳基酰氧基，饱和杂环羰基氧基，烷基磺酰氧基，芳香族磺酰氧基，烷基氨基甲酰氧基或芳族氨基甲酰氧基，R 1任选代表氢烷基，烯基或炔基; R 3，R 4和R 5各自独立地表示氢，烷基或链烯基。

3. 发明申请

WO2011108155A1 PROCESS FOR PRODUCING PYRIPYROPENE DERIVATIVES 审中-公开
标题翻译：生产吡啶衍生物的方法
公开(公告)号：WO2011108155A1
公开(公告)日：2011-09-09
申请号：PCT/JP2010/070414
申请日：2010-11-10
申请人： MEIJI SEIKA KAISHA, LTD. , FUKUDA, Yoshimasa , ANDO, Takashi , GOTO, Kimihiko , NAKANISHI, Nozomu , WATANABE, Takashi , KURIHARA, Kenichi , MINOWA, Nobuto , MITOMI, Masaaki
发明人： FUKUDA, Yoshimasa , ANDO, Takashi , GOTO, Kimihiko , NAKANISHI, Nozomu , WATANABE, Takashi , KURIHARA, Kenichi , MINOWA, Nobuto , MITOMI, Masaaki
IPC分类号： C07D493/04
CPC分类号： C07D493/04
摘要： Disclosed is a process for efficiently producing pyripyropene derivatives having acyloxy at the 1-position and 11-position and hydroxyl at the 7-position. The process comprises selectively acylating hydroxyl at the 1-position and 11-position of a compound represented by formula Bl through one to three steps with an acylating agent in the presence or absence of a base.
摘要翻译：公开了一种有效生产在1-位和11位上具有酰氧基并在7-位具有羟基的吡啶并苯衍生物的方法。该方法包括在存在或不存在碱的情况下，用酰化剂选择性地将式B1化合物的1位和11位羟基选择性酰化1-3步。

4. 发明申请

WO1998027059A1 NOVEL TETRAHYDROBENZINDOLONE DERIVATIVES 审中-公开
标题翻译：新型四氢苯并恶唑衍生物
公开(公告)号：WO1998027059A1
公开(公告)日：1998-06-25
申请号：PCT/JP1997004683
申请日：1997-12-18
申请人： MEIJI SEIKA KAISHA, LTD. , KURIHARA, Kenichi , SHINEI, Rie , KURATA, Yasushi , TABATA, Yuji , TANABE, Kiyoshi , OKONOGI, Tsuneo
发明人： MEIJI SEIKA KAISHA, LTD.
IPC分类号： C07D209/60
CPC分类号： C07D231/12 , C07D209/60 , C07D233/56 , C07D249/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要： Compounds represented by general formula (I) or pharmaceutically acceptable salts thereof and a process for producing the same. Because of having an inhibitory activity on the bonding of progesterone to its receptor, these compounds are usable as remedies and preventives for diseases in which progesterone participates. In particular, these compounds are useful as anticancer agents for mammary cancer and ovarian cancer, remedies for uterus myoma, endometriosis, meningioma and myeloma, abortifacients, oral contraceptives, and remedies and preventives for osteoporosis and menopausual symptoms. In said formula, R represents alkyl or aralkyl; R represents hydrogen, alkylcarbonyl, cycloalkyl- carbonyl, aromatic acyl, saturated heterocyclic acyl, alkyl, alkenyl, aralkyl, carbamoyl, alkylcarbamoyl, aromatic carbamoyl, aralkylcarbamoyl, alkylamino-carbonyl, cycloalkylcarbamoyl, alkoxycarbonyl, aryloxycarbonyl, heteroaromatic thiocarbonyl, saturated heterocyclic thiocarbonyl or alkylthiocarbamoyl; and R represents hydrogen, hydroxy, alkyloxy, alkylcarbonyloxy, alkylthio or arylthio.
摘要翻译：由通式（I）表示的化合物或其药学上可接受的盐及其制备方法。由于对孕酮与其受体的结合具有抑制活性，这些化合物可用作孕酮参与的疾病的补救措施和预防药物。特别地，这些化合物可用作乳腺癌和卵巢癌的抗癌剂，子宫肌瘤，子宫内膜异位症，脑膜瘤和骨髓瘤的补救剂，流产者，口服避孕药以及用于骨质疏松症和更年期症状的治疗剂和预防剂。在所述式中，R 1表示烷基或芳烷基; R 2表示氢，烷基羰基，环烷基 - 羰基，芳族酰基，饱和杂环酰基，烷基，烯基，芳烷基，氨基甲酰基，烷基氨基甲酰基，芳族氨基甲酰基，芳烷基氨基甲酰基，烷基氨基 - 羰基，环烷基氨基甲酰基，烷氧基羰基，芳氧基羰基，杂芳硫基羰基，饱和杂环硫代羰基或烷硫基氨基甲酰基; R 3表示氢，羟基，烷氧基，烷基羰氧基，烷硫基或芳硫基。

5. 发明专利

JP2003193356A ANTIMICROBIAL DEODORANT KNITTED PRODUCT AND METHOD FOR PRODUCING THE SAME 审中-公开
公开(公告)号：JP2003193356A
公开(公告)日：2003-07-09
申请号：JP2001402854
申请日：2001-12-20
申请人： KURIHARA KENICHI
发明人： KURIHARA KENICHI
IPC分类号： D06C29/00 , D02G3/02 , D04B1/16 , D04B1/18 , D04B1/26
摘要： PROBLEM TO BE SOLVED: To simply provide a knitted product, such as stocking, which maintains flexibility and elasticity, has an antimicrobial deodorant effect and a blood circulation-improving effect for improving excessive sensitivity to cold or the like, and stably maintains the shape even when worn for a long period, at a low cost, and further to contribute to the saving of resources. SOLUTION: This antimicrobial deodorant knitted product is knitted from a magnetic non-elastic filament (especially a filament obtained by drawing a used magnetic tape) which is a 80 to 1,000 dtex monofilament, a non-elastic yarn comprising ≤10 dtex filaments and having a total fineness of 30-1,000 dtex, and a 50 to 3,000 dtex elastic yarn. And a method for producing the antimicrobial deodorant knitted product. COPYRIGHT: (C)2003,JPO

6. 发明专利

JPH09228774A PIPE ASSEMBLY AND METHOD FOR PUMPING UP UNDERGROUND HOT WATER AND METHOD FOR UTILIZING UNDERGROUND HOT WATER 失效
公开(公告)号：JPH09228774A
公开(公告)日：1997-09-02
申请号：JP7083896
申请日：1996-02-21
申请人： KURIHARA KENICHI , ISHII YUTARO
发明人： KURIHARA KENICHI , ISHII YUTARO
IPC分类号： E21B43/10 , E21B43/14
摘要： PROBLEM TO BE SOLVED: To strike 25 deg.-C hot water with high probability and to reduce the required time and cost by providing a projection on a part of a pipe. SOLUTION: This pipe for pumping up underground hot water comprises a plurality of pipes 10, 14, 16 coupled to one another. This pipe assembly has a projecting member 12 extending upward from at least one of the pipes. Further, the pipe assembly is provided with an opening in the portion of the pipe above or below the projecting member.

7. 发明专利

JPH0921281A DOUBLE-STRUCTURE PLATES-SHAPED SCREEN DEVICE AND MANUFACTURE THEREOF 失效
公开(公告)号：JPH0921281A
公开(公告)日：1997-01-21
申请号：JP20124295
申请日：1995-07-05
申请人： KURIHARA KENICHI , YOSHIDA TAKEO
发明人： KURIHARA KENICHI
IPC分类号： E06B9/262 , B32B3/12 , E06B9/06
摘要： PROBLEM TO BE SOLVED: To provide a double-structure pleats-shaped screen device and its manufacture in a short time at a low cost regardless of the thickness and/or nature of a screen material so far as the screen material can be machined into the pleats shape. SOLUTION: Screens 12 integrally formed into a pleats shape having an optional length are arranged face to face for manufacturing a double-structure pleats-shaped screen device. Connecting members 14-1, 14-2 for connecting the screens 12 are suspended between the insides of the mating screens 12. An operation or guide cord is inserted into nearly the centers of the connecting members 14-1, 14-2. The connecting members 14-1, 14-2 are pinched between the mating screens 12 after the connecting members 14-1, 14-2 are suspended between the insides of the mating screens 12, and the screens 12 are folded, hot-pressed, and firmly fixed in this state.

8. 发明专利

JPH1157578A DRYING DEVICE AND MATERIAL TO BE DRIED 失效
公开(公告)号：JPH1157578A
公开(公告)日：1999-03-02
申请号：JP25743097
申请日：1997-08-19
申请人： KURIHARA KENICHI
发明人： IZUMI MASAHIKO
IPC分类号： F26B3/347 , B05C9/14
摘要： PROBLEM TO BE SOLVED: To provide a drying device capable of manufacturing a high quality product and a material to be dried by wholly and evenly heating the material to be dried while applying far infrared ray from a far infrared radiating body to the material to be dried provided on the surface of a base part to dry with a short drying time without the evil influence of an exhaust gas. SOLUTION: The drying device for drying a member to be dried provided on an article by irradiating the member to be dried with the far infrared ray from the radiation surface of the far infrared radiating body 16 provided with a radiation layer having a prescribed radius of curvature. The far infrared radiating body 16 emits far infrared ray having 3-7 μ wavelength band and simultaneously generates electromagnetic wave. The far infrared radiating body 16 has a spectral emissivity of 0.9 in 3-7 μ wavelength band.

9. 发明专利

JP2013024020A Screen device 审中-公开
标题翻译：屏幕设备
公开(公告)号：JP2013024020A
公开(公告)日：2013-02-04
申请号：JP2011170521
申请日：2011-07-18
申请人： Tomomichi Chigusa , 智道千種 , Kurihara Kenichi , 栗原健一
发明人： CHIGUSA TOMOMICHI
IPC分类号： E06B9/06
摘要： PROBLEM TO BE SOLVED: To solve the problem that, a rigid band body is distorted by the weight of a pleated screen to damage horizontality at an upper end edge of the pleated screen, pleats are protruded, expanded or disordered by rigidity or plastic deformation of the pleated screen in approach of a post to increase air pressure between posts disposed oppositely especially when reducing the distance between the posts, so that considerable protrusion or disorder may occur and the pleated screen may become extremely bad in appearance.SOLUTION: In a screen device, between an inner right slope of one of pleated screens which are disposed while being opposed to each other and integrally formed in a pleated shape with an arbitrary length, and an inner left slope of the other pleated screen, an upper screen setter disposed in an upper part and a lower screen setter disposed in a lower part are installed while being divided vertically, and the pleated screens are spread over a first post and a second post which are opposed to each other.
摘要翻译：要解决的问题为了解决刚性带体被褶皱筛网的重量扭曲以破坏褶皱筛网的上端边缘处的水平度的问题，褶皱由于刚度而突出，膨胀或无序，在接近柱子时褶皱筛网的塑性变形，以增加相对设置的柱之间的空气压力，特别是当减小柱之间的距离时，可能发生相当大的突起或紊乱，并且打褶的筛网在外观上可能变得非常差。解决方案：在屏幕装置中，在彼此相对并一体地形成为具有任意长度的打褶形状并且另一个褶皱的内部左斜面之间布置的打褶屏幕之一的内右斜面之间屏幕，布置在上部的上屏幕设置器和设置在下部的下屏幕设置器被安装在垂直分割处，并且打褶的屏幕分布在彼此相对的第一柱和第二柱上。版权所有（C）2013，JPO＆INPIT

10. 发明专利

JP2000225389A WATER TREATMENT APPARATUS AND STERILIZING APPARATUS 失效
公开(公告)号：JP2000225389A
公开(公告)日：2000-08-15
申请号：JP5911099
申请日：1999-02-01
申请人： KURIHARA KENICHI , ISHII YUTARO
发明人： ISHII YUTARO , KURIHARA KENICHI
IPC分类号： B01D19/00 , C02F1/20 , C02F1/78
摘要： PROBLEM TO BE SOLVED: To prevent the generation of rust or the like in the piping of a building or an apartment while sterilizing water, to easily obtain drinking water and to obtain water having no oxygen and ozone dissolved therein at a high speed in high concn. SOLUTION: A water treatment apparatus 50 is equipped with an ozone dissolving tank 54 for making water in which ozone molecules are dissolved in a concn. of 1 ppm or more, pref., 4 ppm or more and degassing devices 52, 56 ejecting water in which ozone and oxygen molecules are dissolved in the ozone dissolving tank under vacuum in a fine particulate state to make water from which ozone and oxygen molecules are removed. Ozone molecules are made by using oxygen and ozone molecules discharged from the degassing devices.

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