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    • 3. 发明授权
    • Capacitance type load sensor
    • 电容式负载传感器
    • US06556024B2
    • 2003-04-29
    • US09819958
    • 2001-03-28
    • Katsutoshi SasakiKen ObataHiroyuki Yamazaki
    • Katsutoshi SasakiKen ObataHiroyuki Yamazaki
    • G01R2726
    • G01L1/142
    • A capacitance type load sensor is provided with outer and inner tubes made of plastic and formed into a hollow circular cylinder shape and outer and inner electrodes respectively attached to the inner and outer peripheral faces of the outer and inner tubes. A coil spring is disposed within the interior space of the inner tube, and load-applied hooks of the coil spring are individually coupled to respective end walls of the outer and inner tubes. When a tensile load is applied to the hooks of the coil spring and hence the coil spring is elongated, a relative motion occurs between the outer and inner tubes so that the facing area between the outer and inner electrodes and accordingly the capacitance between these electrodes decrease. The load sensor measures the applied load based on an amount of change in the capacitance between before and after the application of the load.
    • 电容式负载传感器设有由塑料制成的外管和内管,并形成为中空的圆筒形,外电极和内电极分别安装在外管和内管的内外周面上。 螺旋弹簧设置在内管的内部空间内,并且螺旋弹簧的负载施加的钩单独地联接到外管和内管的相应的端壁。 当拉伸载荷施加到螺旋弹簧的钩上并因此螺旋弹簧伸长时,在外管和内管之间发生相对运动,使得外电极和内电极之间的相对面积以及相应地这些电极之间的电容减小 。 负载传感器基于负载施加之前和之后的电容变化量来测量施加的负载。
    • 5. 发明授权
    • Polypeptides
    • 多肽
    • US07291491B2
    • 2007-11-06
    • US10166098
    • 2002-06-11
    • Minoru FukudaKatsutoshi SasakiKazumi MiuraSatoshi NakagawaTatsunari NishiSusumu Sekine
    • Minoru FukudaKatsutoshi SasakiKazumi MiuraSatoshi NakagawaTatsunari NishiSusumu Sekine
    • C12N9/10C07H21/04C12P21/06
    • C12N9/1051
    • The present invention provides pharmaceutical preparations for anti-inflammation, anti-infection, inhibition of cancer metastasis etc., foods such as dairy products etc., and a method for improving proteins, as well as a method for diagnosis of inflammatory diseases and cancer malignancy. According to the present invention, there can be provided a polypeptide having poly-N-acetyllactosamine sugar chains synthesis-related activity, a process for producing the polypeptide, DNA coding for the polypeptide, a process for producing the DNA, a recombinant vector having the DNA integrated therein, a transformant carrying the recombinant vector, an antibody recognizing the polypeptide, a process for producing poly-N-acetyllactosamine sugar chains by use of the DNA or the polypeptide, diagnosis and treatment of diseases such as inflammations, cancers etc. by use of the DNA, the polypeptide or the antibody, determination and immunostaining of the polypeptide of the present invention by use of the antibody, a method for screening a compound varying the expression of a gene coding for the polypeptide, and a method for screening a substance varying the activity of the polypeptide.
    • 本发明提供抗炎,抗感染,癌转移抑制等药物制剂,乳制品等食品,以及改善蛋白质的方法,以及炎性疾病和癌症恶性肿瘤的诊断方法 。 根据本发明,可以提供具有聚-N-乙酰乳糖胺糖链合成相关活性的多肽,制备多肽的方法,编码多肽的DNA,制备DNA的方法,具有 整合在其中的DNA,携带重组载体的转化体,识别多肽的抗体,使用DNA或多肽产生聚-N-乙酰乳糖胺糖链的方法,诊断和治疗诸如炎症,癌症等疾病,通过 使用DNA,多肽或抗体,通过使用抗体测定和免疫染色本发明的多肽,筛选改变编码多肽的基因的表达的化合物的方法,以及筛选方法 物质改变多肽的活性。
    • 9. 发明授权
    • Processes for reproducing sugar nucleotides and complex carbohydrates
    • 复制糖核苷酸和复合碳水化合物的方法
    • US06821756B2
    • 2004-11-23
    • US09068528
    • 1998-05-13
    • Satoshi KoizumiKatsutoshi SasakiTetsuo EndoKazuhiko TabataAkio Ozaki
    • Satoshi KoizumiKatsutoshi SasakiTetsuo EndoKazuhiko TabataAkio Ozaki
    • C12P1930
    • C12P19/30
    • This invention relates to a process for producing a sugar nucleotide, in which a) a culture broth of a microorganism capable of producing NTP from a nucleotide precursor, or a treated product of the culture broth, and b) a culture broth of a microorganism capable of producing a sugar nucleotide from a sugar and NTP, or a treated product of the culture broth, are used as enzyme sources; a process for producing a complex carbohydrate, in which the above-described a) and b) and c) a culture broth of a microorganism, an animal cell or an insect cell capable of producing a complex carbohydrate from a sugar nucleotide and a complex carbohydrate precursor, or a treated product of the culture broth, are used as enzyme sources; a process for producing a complex carbohydrate, in which a culture broth of a microorganism, an animal cell or an insect cell capable of producing a complex carbohydrate from a sugar nucleotide and a complex carbohydrate precursor, or a treated product of the culture broth, is as an enzyme source; and a process for producing N-acetylglucosamine-1-phosphate, in which a culture broth of a microorganism having strong galactokinase activity, or a treated product of the culture broth, is used as the enzyme source.
    • 本发明涉及一种制备糖核苷酸的方法,其中a)从核苷酸前体产生NTP的微生物的培养液或培养液的处理产物,和b)能够培养的微生物的培养液 从糖和NTP生产糖核苷酸或培养液的处理产物用作酶源; 复合碳水化合物的制造方法,其中上述a)和b)和c)能够从糖核苷酸和复合碳水化合物生产复合碳水化合物的微生物,动物细胞或昆虫细胞的培养液 前体或培养液的处理产物用作酶源; 复合碳水化合物的制造方法,其中可以从糖核苷酸和复合碳水化合物前体生产复合碳水化合物的微生物,动物细胞或昆虫细胞的培养液或培养液的处理产物是 作为酶源; 使用其中具有强烈的半乳糖激酶活性的微生物的培养液或培养液的处理产物的N-乙酰葡糖胺-1-磷酸的生产方法作为酶源。