专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050154066A1 Antiaging composition 审中-公开
标题翻译：抗衰老成分
公开(公告)号：US20050154066A1
公开(公告)日：2005-07-14
申请号：US11029493
申请日：2005-01-06
申请人： Kenji Fujii , Taizo Kawabe , Hiroshi Kubo , Keiichi Higuchi
发明人： Kenji Fujii , Taizo Kawabe , Hiroshi Kubo , Keiichi Higuchi
IPC分类号： A61K8/35 , A61K9/14 , A61K9/20 , A61K31/075 , A61K31/12 , A61Q7/00 , A61Q19/08
CPC分类号： A61K8/347 , A61K8/355 , A61K9/146 , A61K9/2077 , A61K31/075 , A61K31/12 , A61Q7/00 , A61Q19/08
摘要： The object of the present invention is to provide a composition which is effective in retarding or preventing the development of energy decrease, appearance change, etc. of humans and animals due to aging, and is highly safe even with a long period of taking. The present invention relates to an antiaging composition which comprises reduced coenzyme Q as an active ingredient. By feeding mice which develop the aging symptom early (aging-accelerated model mice) with a feed containing reduced coenzyme Q10 for a long period of time, aging process was prevented and retarded. Furthermore, aging-accelerated model mice fed with reduced coenzyme Q10 for a long period of time showed no toxic symptom, thus it was found that the antiaging composition comprising a composition containing said substance can be made into a safe antiaging composition capable of being taken for a long period of time.
摘要翻译：本发明的目的是提供一种有效地延缓或预防由于老化引起的人和动物的能量减少，外观变化等的组合物，并且即使长时间服用也是高度安全的。本发明涉及包含还原型辅酶Q作为活性成分的抗衰老组合物。通过喂养含有还原型辅酶Q 10的饲料长时间喂养老化症状的老鼠（老化加速模型小鼠），防止和延缓衰老过程。此外，长时间喂养还原型辅酶Q1010的老化加速模型小鼠显示没有毒性症状，因此发现包含含有所述物质的组合物的抗衰老组合物可制成安全的抗衰老组合物能够长时间服用。

2. 发明授权

US07708990B2 Coenzyme Q compositions persisting in blood 有权
标题翻译：辅酶Q组合物持续存在血液
公开(公告)号：US07708990B2
公开(公告)日：2010-05-04
申请号：US11085181
申请日：2005-03-22
申请人： Kenji Fujii , Taizo Kawabe , Hiroshi Kubo
发明人： Kenji Fujii , Taizo Kawabe , Hiroshi Kubo
IPC分类号： A61K38/43 , A01N31/14
CPC分类号： A61K31/122 , Y10S514/824 , Y10S514/878 , Y10S514/879
摘要： The object of the present invention is to provide a composition maintaining a blood coenzyme Q concentration at a high level in blood for a prolonged period of time, in order to surely attain an effect of coenzyme Q, which can be expected to manifest a superior effect in maintaining health in humans and animals.By using a composition which comprises a coenzyme Q being a mixture of a reduced coenzyme Q and an oxidized coenzyme Q with the proportion of the reduced coenzyme Q to the whole coenzyme Q of more than 95% by weight, the present invention can attain a high maximum blood concentration of a coenzyme Q as well as long maintenance of high concentration of coenzyme Q in blood for a prolonged period of time, and the area under the blood concentration curve (AUC) can be expanded.
摘要翻译：本发明的目的是提供一种维持血液辅酶Q浓度在血液中长时间保持的组合物，以确保达到辅酶Q的效果，其可以预期表现出优异的效果维持人类和动物的健康。通过使用包含还原型辅酶Q和还原型辅酶Q的还原型辅酶Q与整个辅酶Q的比例大于95重量％的辅酶Q的混合物的组合物，本发明可以达到高辅酶Q的最大血液浓度以及血液中长时间维持高浓度辅酶Q长时间，血液浓度曲线下面积（AUC）可以扩大。

3. 发明申请

US20060073131A1 Coenzyme Q compositions persisting in blood 有权
标题翻译：辅酶Q组合物持续存在血液
公开(公告)号：US20060073131A1
公开(公告)日：2006-04-06
申请号：US11085181
申请日：2005-03-22
申请人： Kenji Fujii , Taizo Kawabe , Hiroshi Kubo
发明人： Kenji Fujii , Taizo Kawabe , Hiroshi Kubo
IPC分类号： A61K38/43 , A61K31/12
CPC分类号： A61K31/122 , Y10S514/824 , Y10S514/878 , Y10S514/879
摘要： The object of the present invention is to provide a composition maintaining a blood coenzyme Q concentration at a high level in blood for a prolonged period of time, in order to surely attain an effect of coenzyme Q, which can be expected to manifest a superior effect in maintaining health in humans and animals. By using a composition which comprises a coenzyme Q being a mixture of a reduced coenzyme Q and an oxidized coenzyme Q with the proportion of the reduced coenzyme Q to the whole coenzyme Q of more than 95% by weight, the present invention can attain a high maximum blood concentration of a coenzyme Q as well as long maintenance of high concentration of coenzyme Q in blood for a prolonged period of time, and the area under the blood concentration curve (AUC) can be expanded.
摘要翻译：本发明的目的是提供一种维持血液辅酶Q浓度在血液中长时间保持的组合物，以确保达到辅酶Q的效果，其可以预期表现出优异的效果维持人类和动物的健康。通过使用包含还原型辅酶Q和还原型辅酶Q的还原型辅酶Q与整个辅酶Q的比例大于95重量％的辅酶Q的混合物的组合物，本发明可以达到高辅酶Q的最大血液浓度以及血液中长时间维持高浓度辅酶Q长时间，血液浓度曲线下面积（AUC）可以扩大。

4. 发明申请

US20090246186A1 AGENT FOR IMPROVING NERVOUS SYSTEM CELL FUNCTIONS 审中-公开
标题翻译：改善神经系统细胞功能的代理
公开(公告)号：US20090246186A1
公开(公告)日：2009-10-01
申请号：US12295258
申请日：2007-03-29
申请人： Yoshiyuki Shinagawa , Hideyuki Kishida , Taizo Kawabe , Hirokazu Sakamoto , Hiroshi Kubo , Kazunori Hosoe
发明人： Yoshiyuki Shinagawa , Hideyuki Kishida , Taizo Kawabe , Hirokazu Sakamoto , Hiroshi Kubo , Kazunori Hosoe
IPC分类号： A61K31/122 , A61P25/00
CPC分类号： A61K31/09 , A61K31/122
摘要： The present invention aims to activate neural cells in brain, and further provide a useful composition having an action to protect intracerebral neural cells from external and internal stresses.An agent for improving a neural cell function containing reduced coenzyme Q as an active ingredient, more specifically, an agent for activating neural cells and an agent for protecting neural cells, is useful, and can be used for the improvement or prophylaxis of central neurological diseases or neuropathy symptoms derived from or associated with a neurodegenerative disease, promotion of cognitive function or improvement of learning and memory disorders.
摘要翻译：本发明旨在激活脑中的神经细胞，并进一步提供一种有用的组合物，其具有保护脑内神经细胞免受外部和内部应激的作用。用于改善包含还原型辅酶Q作为活性成分的神经细胞功能的药剂，更具体地，用于激活神经细胞的药剂和用于保护神经细胞的药剂是有用的，并且可用于改善或预防中枢神经系统疾病或由神经退行性疾病引起或与之相关的神经病症状，促进认知功能或改善学习和记忆障碍。

5. 发明申请

US20070122400A1 Composition having liver function protecting effect 审中-公开
标题翻译：具有肝功能保护作用的组合物
公开(公告)号：US20070122400A1
公开(公告)日：2007-05-31
申请号：US10580403
申请日：2004-10-29
申请人： Hiroshi Kubo , Kenji Fujii , Kazunori Hosoe
发明人： Hiroshi Kubo , Kenji Fujii , Kazunori Hosoe
IPC分类号： A61K38/43 , A61K31/075
CPC分类号： A61K9/1623 , A23K20/111 , A23K20/30 , A23L33/10 , A23L33/16 , A23V2002/00 , A61K9/146 , A61K9/1652 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/4858 , A61K9/4866 , A61K31/075 , A61K31/09 , A23V2200/32 , A23V2250/314
摘要： The present invention provides a highly safe composition which is effective for protecting liver functions and preventing liver dysfunctions in the case where liver dysfunctions rise by various causes. The present inventors found that oxidized coenzyme Q is effective for protecting liver functions in the absence of selenium and that reduced coenzyme Q has a higher efficacy for protecting liver functions. The composition containing, as the main components, oxidized coenzyme Q and less than 0.01 percent by weight of selenium, or reduced coenzyme Q can be used to protect liver functions. The present invention can provide a highly safe composition which is highly effective for maintaining health.
摘要翻译：本发明提供了一种高度安全的组合物，其在肝功能障碍由各种原因升高的情况下对于保护肝功能和预防肝功能障碍是有效的。本发明人发现，氧化型辅酶Q在不存在硒的情况下对肝功能的保护有效，还原型辅酶Q具有较高的肝功能保护功能。作为主要成分的含有氧化型辅酶Q和小于0.01重量％的硒或还原型辅酶Q的组合物可用于保护肝功能。本发明可以提供高度安全的用于维持健康的组合物。

6. 发明申请

US20080254016A1 Composition For Increasing Anti-Oxidation Activity In Blood 审中-公开
标题翻译：用于增加血液中抗氧化活性的组合物
公开(公告)号：US20080254016A1
公开(公告)日：2008-10-16
申请号：US11909966
申请日：2006-03-28
申请人： Hiroshi Kubo , Kenji Fujii , Kazunori Hosoe
发明人： Hiroshi Kubo , Kenji Fujii , Kazunori Hosoe
IPC分类号： A61K31/122 , A61P7/00
CPC分类号： A61K31/09 , A61K31/122
摘要： The present invention provides a composition capable of maintaining antioxidative activity in blood high by keeping the reduced coenzyme Q10 ratio in blood high after taking coenzyme Q10 even in aged mammals.The present invention relates to a composition which comprises reduced coenzyme Q10 as an active component and enhances the antioxidative activity in blood of aged mammals.
摘要翻译：本发明提供了即使在老化的哺乳动物中，在服用辅酶Q 10之后，通过将血液中的还原型辅酶Q 10比例保持在较低水平，能够维持血液中的抗氧化活性。本发明涉及一种组合物，其包含还原型辅酶Q 10作为活性组分并增强老年哺乳动物血液中的抗氧化活性。

7. 发明申请

US20090246185A1 CARDIAC DYSFUNCTION-AMELIORATING AGENT OR CARDIAC FUNCTION-MAINTAINING AGENT 审中-公开
标题翻译：心脏功能改善剂或心脏功能维持剂
公开(公告)号：US20090246185A1
公开(公告)日：2009-10-01
申请号：US12282448
申请日：2007-03-09
申请人： Hideyuki Kishida , Kenji Fujii , Hiroshi Kubo , Kazunori Hosoe
发明人： Hideyuki Kishida , Kenji Fujii , Hiroshi Kubo , Kazunori Hosoe
IPC分类号： A61K31/122 , C07C43/23 , A61P9/00
CPC分类号： A61K31/122 , A23K20/111 , A23K20/174 , A23L33/10 , A23L33/15 , A23V2002/00 , A61K45/06 , A23V2200/326 , A23V2250/314
摘要： An object of the present invention is to provide a highly safe oral composition superior in a cardiac dysfunction-ameliorating or cardiac function-maintaining action. The present inventors have conducted intensive studies in an attempt to solve the aforementioned problems and found that use of, particularly, reduced coenzyme Q10 from among highly safe coenzyme Q affords a composition useful for amelioration of cardiac dysfunction and maintenance of cardiac function. Accordingly, the present invention provides a cardiac dysfunction-ameliorating agent or cardiac function-maintaining agent containing reduced coenzyme Q as an active ingredient, and a pharmaceutical product, a food, an animal drug, a feed and the like, which contain the agent.
摘要翻译：本发明的目的是提供在心脏功能障碍改善或心脏功能保持作用方面优异的高度安全的口服组合物。本发明人为了解决上述问题进行了深入研究，发现特别是来自高度安全性的辅酶Q中的还原型辅酶Q10的使用提供了用于改善心脏功能障碍和维持心脏功能的组合物。因此，本发明提供含有还原型辅酶Q作为活性成分的心脏功能障碍改善剂或心脏功能维持剂，以及含有该药剂的药物，食品，动物药物，饲料等。

8. 发明授权

US11102364B2 Inclination detecting device, reading device, image processing apparatus, and method of detecting inclination 有权
公开(公告)号：US11102364B2
公开(公告)日：2021-08-24
申请号：US16776521
申请日：2020-01-30
申请人： Yuuki Nakada , Hajime Tsukahara , Hiroki Shirado , Ayumu Hashimoto , Tomohiko Ono , Tatsuya Ozaki , Hiroshi Kubo , Yoshiaki Nagao , Kimiharu Yanagisawa , Masahiro Itoh
发明人： Yuuki Nakada , Hajime Tsukahara , Hiroki Shirado , Ayumu Hashimoto , Tomohiko Ono , Tatsuya Ozaki , Hiroshi Kubo , Yoshiaki Nagao , Kimiharu Yanagisawa , Masahiro Itoh
IPC分类号： H04N1/04 , H04N1/00
摘要： An inclination detecting device includes processing circuitry. The processing circuitry is configured to detect, in image information that is an image of an object imaged by an imaging device at an imaging position where a background member forms a background, a first boundary between the background member and a shadow of the object at detection positions in at least one of main-scanning and sub-scanning directions on an outline of the object; detect a second boundary between the object and the shadow of the object at detection positions in at least one of the main-scanning and sub-scanning directions on the outline of the object in the image information; detect a boundary group including detection results of the second boundary at the detection positions; and detect an inclination of the object in the image information from detection results of the first boundary, the second boundary, and the boundary group.

9. 发明授权

US09013763B2 Image reading apparatus and image forming apparatus 有权
标题翻译：图像读取装置和图像形成装置
公开(公告)号：US09013763B2
公开(公告)日：2015-04-21
申请号：US14134510
申请日：2013-12-19
申请人： Hiroshi Kubo , Hidehiko Fujiwara , Atsushi Kanaya , Shinya Kitaoka , Takeshi Akai , Fumiyuki Heishi , Takehisa Shimazu , Koki Sakano , Takuya Sano
发明人： Hiroshi Kubo , Hidehiko Fujiwara , Atsushi Kanaya , Shinya Kitaoka , Takeshi Akai , Fumiyuki Heishi , Takehisa Shimazu , Koki Sakano , Takuya Sano
IPC分类号： H04N1/04 , H04N1/12 , H04N1/193
CPC分类号： H04N1/123 , H04N1/0464 , H04N1/1235 , H04N1/193 , H04N2201/0081 , H04N2201/0456
摘要： An image reading apparatus includes: a transmitting glass; and a step member that is located upstream of a reading position, at which an image of a conveyed document is read by a reading unit via a transmitting glass, in a conveying direction of the document, and has a document guiding surface at a position away from a surface of a transmitting glass by a prescribed distance and forms a step between the document guiding surface and the transmitting glass. The step member is provided with a protrusion protruding downstream in the conveying direction of the document to form space between the transmitting glass and a downstream part of the step member in the conveying direction of the document.
摘要翻译：一种图像读取装置，包括：透射玻璃; 以及台阶构件，位于读取位置的上游，在所述阅读位置的上方，通过透印玻璃，通过读取单元沿着所述文件的传送方向读取所传送的文件的图像，并且在文档的传送方向上具有文档引导表面从传送玻璃的表面起规定的距离，并在文件引导表面和透射玻璃之间形成台阶。台阶部件具有在文件的传送方向上向下游突出的突出部，以在文件的传送方向上在传送玻璃与台阶部件的下游部分之间形成空间。

10. 发明授权

US08950743B2 Automatic document feeder, image reading device including the same, and image forming apparatus including the same 有权
标题翻译：自动送稿器，包括该图像读取装置的图像读取装置以及包括该自动送纸器的图像形成装置
公开(公告)号：US08950743B2
公开(公告)日：2015-02-10
申请号：US14069507
申请日：2013-11-01
申请人： Koki Sakano , Hiroshi Kubo , Shinya Kitaoka , Takeshi Akai , Hidehiko Fujiwara , Atsushi Kanaya , Fumiyuki Heishi , Takuya Sano
发明人： Koki Sakano , Hiroshi Kubo , Shinya Kitaoka , Takeshi Akai , Hidehiko Fujiwara , Atsushi Kanaya , Fumiyuki Heishi , Takuya Sano
IPC分类号： B65H83/00 , B65H7/20 , B65H7/02
CPC分类号： B65H7/20 , B65H5/062 , B65H7/02 , B65H2402/441 , B65H2404/144 , B65H2404/6111 , B65H2405/3321 , B65H2511/417 , B65H2511/515 , B65H2551/27 , B65H2801/06 , B65H2801/39 , G03G15/602 , B65H2220/01 , B65H2220/11 , B65H2220/02
摘要： According to an embodiment, an ADF that feeds and conveys original document sheets one sheet by one sheet from a tray unit to a read position on a document glass by motive power from a driving motor includes: an opening/closing unit operable to open and close relative to the document glass; an open/close detection sensor that detects an open/closed state of the opening/closing unit; a first interlock switch, which is arranged between a power source and the driving motor, that is on when the opening/closing unit is closed, and vice versa; and a control circuit that determines the open/closed state of the opening/closing unit based on detection outputs of the first interlock switch and the open/close detection sensor. The control circuit determines that the opening/closing unit is in the closed state when the first interlock switch is on and the open/close detection sensor is detecting the closed state.
摘要翻译：根据一个实施例，通过来自驱动电动机的动力将原稿从纸盘单元一张纸馈送到文档玻璃上的读取位置的ADF包括：可操作以打开和关闭的打开/关闭单元相对于文件玻璃; 检测开/关单元的打开/关闭状态的打开/关闭检测传感器; 布置在电源和驱动电动机之间的第一联锁开关，当打开/关闭单元关闭时，该开关反之亦然; 以及控制电路，其基于第一互锁开关和打开/关闭检测传感器的检测输出来确定打开/关闭单元的打开/关闭状态。当第一互锁开关接通并且打开/关闭检测传感器检测到关闭状态时，控制电路确定打开/关闭单元处于关闭状态。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式