专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

FI20040772A0 未知
公开(公告)号：FI20040772A0
公开(公告)日：2004-06-04
申请号：FI20040772
申请日：2004-06-04
申请人： KORPIMAEKI TEEMU , NURMI JUSSI , LOEVGREN TIMO , IITIAE ANTTI , KOJOLA HANNU
发明人： NURMI JUSSI , KORPIMAEKI TEEMU , LOEVGREN TIMO , IITIAE ANTTI , KOJOLA HANNU
IPC分类号： G05D20060101 , G05D

2. 发明专利

FI20040768A0 未知
公开(公告)号：FI20040768A0
公开(公告)日：2004-06-04
申请号：FI20040768
申请日：2004-06-04
申请人： KORPIMAEKI TEEMU , NURMI JUSSI , LOEVGREN TIMO
发明人： KORPIMAEKI TEEMU , LOEVGREN TIMO , NURMI JUSSI
IPC分类号： C12Q20060101 , C12Q1/68 , C12Q
摘要： A reagent container having an inner surface upon which at least two reagents are dried, with the first reagent dried on a first area separate from a second area where the second reagent is dried. The first and second reagents are a nucleic acid polymerase and its substrate. A method is disclosed which includes dispensing at least the first and second reagents onto separate areas of the inner surface of the reagent container, and removing excess water from the reagents. The reagent container can be used in a polymerase chain reaction (PCR) assay, an assay that utilizes a reverse transcriptase, a reverse transcriptase polymerase chain reaction, an immuno-PCR assay, a nucleic acid sequence based assay, a proximity ligation assay, a ligase chain reaction assay, a rolling circle amplification assay, and a strand displacement amplification assay.

3. 发明申请

WO2010130877A2 METHOD FOR DETECTING NUCLEIC ACIDS 审中-公开
标题翻译：检测核酸的方法
公开(公告)号：WO2010130877A2
公开(公告)日：2010-11-18
申请号：PCT/FI2010050380
申请日：2010-05-11
申请人： ABACUS DIAGNOSTICA OY , VON LODE PIIA , SYRJAELAE ANNIINA , LOEVGREN TIMO , SOUKKA TERO
发明人： VON LODE PIIA , SYRJAELAE ANNIINA , LOEVGREN TIMO , SOUKKA TERO
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6818 , C12Q1/689 , C12Q2537/161 , C12Q2527/107 , C12Q2525/204 , C12Q2565/107
摘要： This invention relates to detecting nucleic acids. It employs a double-stranded oligonucleotide probe comprising i)a first probe comprising a first label moiety capable of emitting a measurable signal, and ii) a second probe being partially complementary with the first probe and comprising a second label moiety capable of interacting with the first moiety when brought in close proximity with each other, the second moiety being a quencher or acceptor of emission of the first moiety. The first or second probe comprises a sequence being complementary to that of a target nucleotide, and the second or first probe, respectively, comprises a sequence being complementary to a complement of the target nucleotide sequence of the nucleic acid to be detected. The first and the second moieties are attached to the first and second probes respectively in a manner wherein the distance between the first and second moieties is not more than 7 base pairs apart. The complementary sequences of the double-stranded probe is shorter than the full sequence of both the first and second single-stranded probes. The first and second probes have a higher Tm when hybridized with the target nucleotide sequence compared to the Tm of the double-stranded probe. The intensity of the signal of the first label when the first probe is not hybridized to the second probe is higher or lower than the intensity of the signal of the first label when the first probe is hybridized to the second probe. This invention also relates to oligonucleotides for determining Chlamydia trachomatis.
摘要翻译：本发明涉及检测核酸。其采用双链寡核苷酸探针，其包含i）第一探针，其包含能够发射可测量信号的第一标记部分，和ii）与第一探针部分互补的第二探针，并且包含能够与当第一部分彼此靠近时，第二部分是第一部分的发射的猝灭剂或受体。第一或第二探针包含与靶核苷酸互补的序列，第二或第一探针分别包含与被检测核酸的靶核苷酸序列的互补序列互补的序列。第一和第二部分分别以第一和第二部分之间的距离不超过7个碱基对的方式连接到第一和第二探针。双链探针的互补序列比第一和第二单链探针的全序列短。当与靶核苷酸序列杂交时，与双链探针的Tm相比，第一和第二探针具有更高的Tm。当第一探针不与第二探针杂交时，第一标记的信号的强度比第一标记与第二探针杂交时的第一标记的信号的强度高或低。本发明还涉及确定沙眼衣原体的寡核苷酸。

4. 发明专利

DE602004008243D1 未知
公开(公告)号：DE602004008243D1
公开(公告)日：2007-09-27
申请号：DE602004008243
申请日：2004-02-24
申请人： SOUKKA TERO , HAERMAE HARRI , LOEVGREN TIMO
发明人： SOUKKA TERO , HAERMAE HARRI , LOEVGREN TIMO
IPC分类号： G01N33/58 , G01N33/542

5. 发明专利

FI20030140A0 未知
公开(公告)号：FI20030140A0
公开(公告)日：2003-01-30
申请号：FI20030140
申请日：2003-01-30
申请人： HELLMAN JUKKA , KAEKOENEN SANNA-MARIA , LOEVGREN TIMO , IVASKA KAISA , VAEAENAENEN KALERVO , PETTERSSON KIM
发明人： IVASKA KAISA , HELLMAN JUKKA , KAEKOENEN SANNA-MARIA , LOEVGREN TIMO , VAEAENAENEN KALERVO , PETTERSSON KIM
IPC分类号： C12Q20060101 , C12Q

6. 发明专利

FI990693A0 未知
公开(公告)号：FI990693A0
公开(公告)日：1999-03-29
申请号：FI990693
申请日：1999-03-29
申请人： KAEKOENEN SANNA MARIA , LUUKINEN HEIKKI , PETTERSSON KIM , LOEVGREN TIMO , VAEAENAENEN H KALERVO
发明人： KAEKOENEN SANNA-MARIA , LUUKINEN HEIKKI , PETTERSSON KIM , LOEVGREN TIMO , VAEAENAENEN H KALERVO
IPC分类号： G01N33/68
摘要： This invention concerns a method for the assessment of bone fragility and fracture risk, or osteoporosis, in a person. In said method, the concentration of gamma-carboxylated osteocalcin (COC) and optionally also the concentration of intact or total osteocalcin (IOC or TOC, respectively) in a body fluid sample of said person is measured. The concentration of gamma-carboxylated osteocalcin (COC) so obtained is compared to the mean concentration of gamma-carboxylated osteocalcin (mean COC) in similar body fluid samples of the population of the same age and sex. Alternatively, the determined ratio COC/IOC or COC/TOC for said person, is compared to the mean ratio COC/IOC or COC/TOC, (mean ratio COC/IOC or mean ratio COC/TOC) determined from measurements in similar body fluid samples of the population of the same age and sex. A measured COC that is lower than the mean COC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. Preferably, a determined ratio COC/TOC that is lower than the mean ratio COC/TOC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. The invention concerns further kits for use in the assessment according to this invention.

7. 发明专利

DE602004008243T2 未知
公开(公告)号：DE602004008243T2
公开(公告)日：2008-05-15
申请号：DE602004008243
申请日：2004-02-24
申请人： SOUKKA TERO , HAERMAE HARRI , LOEVGREN TIMO
发明人： SOUKKA TERO , HAERMAE HARRI , LOEVGREN TIMO
IPC分类号： G01N33/58 , G01N33/542

8. 发明专利

FI20041275A0 未知
公开(公告)号：FI20041275A0
公开(公告)日：2004-10-01
申请号：FI20041275
申请日：2004-10-01
申请人： HAERMAE HARRI , LOEVGREN TIMO
发明人： HAERMAE HARRI , LOEVGREN TIMO
IPC分类号： C09B20060101 , C09B

9. 发明专利

DE60041534D1 未知
公开(公告)号：DE60041534D1
公开(公告)日：2009-03-26
申请号：DE60041534
申请日：2000-03-20
申请人： KAEKONEN SANNA-MARIA , LOEVGREN TIMO , LUUKINEN HEIKKI , PETTERSSON KIM , VAEAENAENEN H KALERVO
发明人： KAEKONEN SANNA-MARIA , LUUKINEN HEIKKI , PETTERSSON KIM , LOEVGREN TIMO , VAEAENAENEN KALERVO H
IPC分类号： G01N33/68
摘要： This invention concerns a method for the assessment of bone fragility and fracture risk, or osteoporosis, in a person. In said method, the concentration of gamma-carboxylated osteocalcin (COC) and optionally also the concentration of intact or total osteocalcin (IOC or TOC, respectively) in a body fluid sample of said person is measured. The concentration of gamma-carboxylated osteocalcin (COC) so obtained is compared to the mean concentration of gamma-carboxylated osteocalcin (mean COC) in similar body fluid samples of the population of the same age and sex. Alternatively, the determined ratio COC/IOC or COC/TOC for said person, is compared to the mean ratio COC/IOC or COC/TOC, (mean ratio COC/IOC or mean ratio COC/TOC) determined from measurements in similar body fluid samples of the population of the same age and sex. A measured COC that is lower than the mean COC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. Preferably, a determined ratio COC/TOC that is lower than the mean ratio COC/TOC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. The invention concerns further kits for use in the assessment according to this invention.

10. 发明专利

AT422672T 未知
公开(公告)号：AT422672T
公开(公告)日：2009-02-15
申请号：AT00914195
申请日：2000-03-20
申请人： KAEKONEN SANNA-MARIA , LUUKINEN HEIKKI , PETTERSSON KIM , LOEVGREN TIMO , VAEAENAENEN H KALERVO
发明人： KAEKONEN SANNA-MARIA , LUUKINEN HEIKKI , PETTERSSON KIM , LOEVGREN TIMO , VAEAENAENEN H
IPC分类号： G01N33/68
摘要： This invention concerns a method for the assessment of bone fragility and fracture risk, or osteoporosis, in a person. In said method, the concentration of gamma-carboxylated osteocalcin (COC) and optionally also the concentration of intact or total osteocalcin (IOC or TOC, respectively) in a body fluid sample of said person is measured. The concentration of gamma-carboxylated osteocalcin (COC) so obtained is compared to the mean concentration of gamma-carboxylated osteocalcin (mean COC) in similar body fluid samples of the population of the same age and sex. Alternatively, the determined ratio COC/IOC or COC/TOC for said person, is compared to the mean ratio COC/IOC or COC/TOC, (mean ratio COC/IOC or mean ratio COC/TOC) determined from measurements in similar body fluid samples of the population of the same age and sex. A measured COC that is lower than the mean COC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. Preferably, a determined ratio COC/TOC that is lower than the mean ratio COC/TOC is used as indication of osteoporosis, bone fragility or increased risk of bone fracture in said person. The invention concerns further kits for use in the assessment according to this invention.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式