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1. 发明申请

WO2012143831A1 SIMULTANEOUS NON- CONTRAST MR ANGIOGRAPHY AND INTRAPLAQUE HEMORRHAGE (SNAP) MR IMAGING 审中-公开
标题翻译：同时非对照MR血管造影和腹腔镜检查（SNAP）MR成像
公开(公告)号：WO2012143831A1
公开(公告)日：2012-10-26
申请号：PCT/IB2012/051812
申请日：2012-04-13
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , THE UNIVERSITY OF WASHINGTON , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WANG, Jinnan , HELLE, Michael Günter , KERWIN, William Sean , BOERNERT, Peter , YUAN, Chun
发明人： WANG, Jinnan , HELLE, Michael Günter , KERWIN, William Sean , BOERNERT, Peter , YUAN, Chun
IPC分类号： G01R33/56
CPC分类号： G01R33/5635 , G01R33/5602
摘要： Magnetic resonance (MR) spins are inverted by applying an inversion recovery (IR) radio frequency pulse (50). MR signals are acquired at an inversion time (TI) after the IR radio frequency pulse. TI is selected such that a first tissue of interest (e.g., blood) exhibits negative magnetism excited by the IR radio frequency pulse and a second tissue (e.g., intraplaque hemorrhage tissue) exhibits positive magnetism excited by the IR radio frequency pulse. The acquired magnetic resonance signals are reconstructed to generate spatial pixels or voxels wherein positive pixel or voxel values indicate spatial locations of positive magnetism and negative pixel or voxel values indicates spatial locations of negative magnetism. A first image (28) representative of the first tissue is generated from spatial pixels or voxels having negative signal intensities, and a second image (26) representative of the second tissue is generated from spatial pixels or voxels having positive signal intensities.
摘要翻译：通过应用反转恢复（IR）射频脉冲（50）来反转磁共振（MR）自旋。在IR射频脉冲之后，在反转时间（TI）获取MR信号。选择TI，使得感兴趣的第一组织（例如血液）表现出由IR射频脉冲激发的负磁性，并且第二组织（例如，intraplaque出血组织）表现出由IR射频脉冲激发的正磁性。所获取的磁共振信号被重建以产生空间像素或像素，其中正像素或体元值表示正磁性的空间位置，负像素或体素值表示负磁性的空间位置。从具有负信号强度的空间像素或体素生成代表第一组织的第一图像（28），并且从具有正信号强度的空间像素或体素生成代表第二组织的第二图像（26）。

2. 发明申请

WO2012143821A1 MAGNETIC RESONANCE IMAGING OF OBJECT IN MOTION 审中-公开
标题翻译：运动对象的磁共振成像
公开(公告)号：WO2012143821A1
公开(公告)日：2012-10-26
申请号：PCT/IB2012/051760
申请日：2012-04-11
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , DONEVA, Mariya, Ivanova , STEHNING, Christian
发明人： BOERNERT, Peter , DONEVA, Mariya, Ivanova , STEHNING, Christian
IPC分类号： G01R33/561 , G01R33/567 , G01R33/565
CPC分类号： G01R33/565 , G01R33/5611 , G01R33/56509 , G01R33/5673 , G01R33/5676
摘要： A magnetic resonance imaging method includes acquisition of datasets of magnetic resonance data from an object. At least some of the datasets are undersampled in k-space. Each dataset relating to a motion state of the object. Images are reconstructed from each of the datasets by way of a compressed sensing reconstruction. Motion correction is applied to the reconstructed images relative to a selected motion state, so as to generate motion corrected images. A diagnostic image for the selected motion state is derived, e.g. by averaging from the motion corrected images.
摘要翻译：磁共振成像方法包括从对象获取磁共振数据的数据集。至少有一些数据集在k空间中欠采样。每个与物体运动状态相关的数据集。通过压缩感测重构，从每个数据集重建图像。运动校正被应用于相对于所选运动状态的重建图像，以便产生运动校正图像。导出所选运动状态的诊断图像，例如，通过对运动校正图像进行平均。

3. 发明申请

WO2012140536A1 MR IMAGING WITH B1MAPPING 审中-公开
标题翻译：拍摄与拍摄
公开(公告)号：WO2012140536A1
公开(公告)日：2012-10-18
申请号：PCT/IB2012/051590
申请日：2012-04-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VAN DER MEULEN, Peter , BOERNERT, Peter , NEHRKE, Kay
发明人： VAN DER MEULEN, Peter , BOERNERT, Peter , NEHRKE, Kay
IPC分类号： G01R33/24
CPC分类号： G01R33/288 , G01R33/246
摘要： The invention relates to a method of MR imaging, wherein a portion of a body is subjected to an imaging sequence of RF pulses and switched magnetic field gradients, which imaging sequence is a stimulated echo sequence including an off-resonant Bloch- Siegert RF pulse (BS) radiated during a preparation period (21) of the stimulated echo sequence. A B 1 map is derived from the acquired stimulated echo MR signals. Moreover, the invention relates to a method of MR imaging, wherein a portion of a body is subjected to a first imaging sequence, which comprises a first composite excitation RF pulse consisting of two RF pulse components having essentially equal flip angles and being out of phase by essentially 90°. Further, the portion of the body is subjected to a second imaging sequence, wherein a B 1 map is derived from signal data acquired by means of the first and second imaging sequences.
摘要翻译：本发明涉及一种MR成像方法，其中身体的一部分经受RF脉冲和切换磁场梯度的成像序列，该成像序列是受激回波序列，其包括非共振Bloch-Siegert RF脉冲（ BS）在刺激回波序列的准备阶段（21）期间辐射。从获得的受激回波MR信号导出B1图。此外，本发明涉及一种MR成像方法，其中身体的一部分经受第一成像序列，该第一成像序列包括第一复合激励RF脉冲，该第一复合激励RF脉冲由具有基本相等的翻转角并且相位不同的两个RF脉冲分量组成基本上为90°。此外，身体的部分经受第二成像序列，其中从通过第一和第二成像序列获取的信号数据导出B1图。

4. 发明申请

WO2011080697A2 DYNAMIC NUCLEAR POLARIZATION APPARATUS 审中-公开
标题翻译：动态核极化装置
公开(公告)号：WO2011080697A2
公开(公告)日：2011-07-07
申请号：PCT/IB2010/056092
申请日：2010-12-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LEUSSLER, Christoph , WIRTZ, Daniel , BOERNERT, Peter , KEUPP, Jochen , EGGERS, Holger , DAVID, Bernd , OVERWEG, Johannes, Adrianus , ECKART, Rainer
发明人： LEUSSLER, Christoph , WIRTZ, Daniel , BOERNERT, Peter , KEUPP, Jochen , EGGERS, Holger , DAVID, Bernd , OVERWEG, Johannes, Adrianus , ECKART, Rainer
IPC分类号： G01R33/28
CPC分类号： G01R33/62 , G01R33/282 , G01R33/5601 , G01R33/5605 , G01R33/5608 , G01R33/56366 , G01R33/56383
摘要： The invention relates to a dynamic nuclear polarization apparatus (116) for continuous provision of hyperpolarized samples (114) comprising dynamically nuclear polarized nuclear spins, the apparatus (116) comprising a polarization region (106) for polarization of said nuclear spins resulting in said hyperpolarized samples, wherein the apparatus (116) further comprises: a cryostat (102) for cooling the samples (114) in the polarization region (106), a magnet (100) for providing a magnetic field to the cooled samples in the polarization region (106), a radiation source (112) for concurrently to the magnetic field provision providing a nuclear polarizing radiation to the polarization region (106) for receiving the hyperpolarized samples, a sample transport system (104) for continuously receiving unpolarized samples (114), transporting the unpolarized samples to the polarization region (106) for nuclear spin polarization and providing the resulting hyperpolarized samples (114).
摘要翻译：本发明涉及用于连续提供包含动态核极化核自旋的超极化样本（114）的动态核极化装置（116），所述装置（116）包括用于所述核自旋的极化的偏振区域（106），导致所述超极化样品，其中所述设备（116）还包括：用于冷却所述偏振区域（106）中的样品（114）的低温恒温器（102），用于向所述偏振区域中的所述冷却样品提供磁场的磁体（100） 106），用于与磁场提供同时提供用于接收超极化样本的偏振区域（106）的核偏振辐射的辐射源（112），用于连续接收非偏振样本（114）的样本传输系统（104）将非偏振样品运送到用于核自旋极化的偏振区域（106），并提供所得到的超极化样品（114）。

5. 发明申请

WO2010113062A1 ACCELERATED B1 MAPPING 审中-公开
标题翻译：加速B1映射
公开(公告)号：WO2010113062A1
公开(公告)日：2010-10-07
申请号：PCT/IB2010/051225
申请日：2010-03-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , NEHRKE, Kay
发明人： BOERNERT, Peter , NEHRKE, Kay
IPC分类号： G01R33/32 , G01R33/58
CPC分类号： G01R33/5612 , G01R33/246 , G01R33/5659 , G01R33/583 , G01R33/586
摘要： A method comprises: performing a number of B i field mapping sequences (24) using a set of radio frequency transmit coils (11) to acquire a B 1 field mapping data set wherein said number is less than a number of radio frequency transmit coils in the set of radio frequency transmit coils; and determining coil sensitivities (30) for the set of radio frequency transmit coils based on the acquired B1 field mapping data set. In some embodiments, the performed B 1 field mapping sequences are defined by (i) performing a linear transform (40) on the set of radio frequency transmit coils to generate a set of orthogonal virtual radio frequency transmit coils (42) and (ii) selecting (44) a sub- set (46) of the set of orthogonal virtual radio frequency transmit coils that define the performed B 1 field mapping sequences.
摘要翻译：一种方法包括：使用一组射频发射线圈（11）来执行多个B i场映射序列（24），以获取B1场映射数据集，其中所述数小于所述射频发射线圈的数量射频发射线圈组; 以及基于所获取的B1场映射数据集来确定所述一组射频发射线圈的线圈灵敏度（30）。在一些实施例中，所执行的B1场映射序列由（i）在射频发射线圈组上执行线性变换（40）来定义，以产生一组正交虚拟射频发射线圈（42）和（ii）选择（44）定义所执行的B1场映射序列的正交虚拟射频发射线圈组的子集（46）。

6. 发明申请

WO2009118702A3 FLIP ANGLE IMAGING WITH IMPROVED B1 MAPPING FOR MULTI-RF TRANSMIT SYSTEMS 审中-公开
公开(公告)号：WO2009118702A3
公开(公告)日：2009-10-01
申请号：PCT/IB2009/051258
申请日：2009-03-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NEHRKE, Kay , BOERNERT, Peter , VOIGT, Tobias Ratko , KATSCHER, Ulrich
发明人： NEHRKE, Kay , BOERNERT, Peter , VOIGT, Tobias Ratko , KATSCHER, Ulrich
IPC分类号： G01R33/3415 , G01R33/565
摘要： A magnetic resonance method includes performing a plurality of magnetic resonance excitation operations each using a different sub-set of a set of radio frequency transmit coils (30), each sub-set including more than one radio frequency transmit coil, acquiring magnetic resonance data responsive to each said magnetic resonance excitation operation, and computing a B1 or flip angle map for each radio frequency transmit coil of the set of radio frequency transmit coils based on the acquired magnetic resonance data. A magnetic resonance method includes performing an actual flip angle mapping (AFI) sequence using a radio frequency transmit coil (32) with a ratio TR 1 : TR 2 of the TR times of the AFI sequence selected to be rational, acquiring magnetic resonance data responsive to said AFI sequence, and computing a B1 or flip angle map for the radio frequency transmit coil based on the acquired magnetic resonance data.

7. 发明申请

WO2009112987A1 COIL SELECTION FOR PARALLEL MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：并联磁共振成像的线圈选择
公开(公告)号：WO2009112987A1
公开(公告)日：2009-09-17
申请号：PCT/IB2009/050925
申请日：2009-03-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , JURRISSEN, Michel, P., J. , BOERNERT, Peter , DONEVA, Mariya, I. , FUDERER, Miha
发明人： JURRISSEN, Michel, P., J. , BOERNERT, Peter , DONEVA, Mariya, I. , FUDERER, Miha
IPC分类号： G01R33/561 , G01R33/3415
CPC分类号： G01R33/022 , G01R33/3415 , G01R33/3664 , G01R33/543 , G01R33/5611 , G01R33/5659
摘要： The invention relates to a method of selecting a set of coil elements from a multitude of physical coil elements comprised in a coil array for performing a magnetic resonance imaging scan of a region of interest.
摘要翻译：本发明涉及从包括在线圈阵列中的多个物理线圈元件中选择一组线圈元件的方法，用于执行感兴趣区域的磁共振成像扫描。

8. 发明申请

WO2007031916A2 MAGNETIC RESONANCE IMAGING WITH SEVERAL TYPES OF CONTRAST 审中-公开
标题翻译：具有几种对比度的磁共振成像
公开(公告)号：WO2007031916A2
公开(公告)日：2007-03-22
申请号：PCT/IB2006/053167
申请日：2006-09-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , HOOGEVEEN, Romhild, M. , DE BECKER, Jan, F., L. , BOERNERT, Peter , OVERWEG, Johannes, A.
发明人： HOOGEVEEN, Romhild, M. , DE BECKER, Jan, F., L. , BOERNERT, Peter , OVERWEG, Johannes, A.
CPC分类号： G01R33/561
摘要： A magnetic resonance imaging system comprises a signal acquisition system to acquire magnetic resonance signals. A reconstructor reconstructs magnetic resonance images from the acquired magnetic resonance signals. The signal acquisition system and/or the reconstructor are controlled to perform overhead activities separately from actual acquisition of the magnetic resonance signals notably for different contrast types. Accordingly, time efficient signal acquisition for multiple contrasts is achieved.
摘要翻译：磁共振成像系统包括用于采集磁共振信号的信号采集系统。重建器从所采集的磁共振信号重建磁共振图像。控制信号采集系统和/或重建器以独立于实际采集磁共振信号来执行额外开销活动，特别是针对不同的对比度类型。因此，可以实现多种对比度的高效时间信号采集。

9. 发明申请

WO2011161566A1 DYNAMIC CONTRAST ENHANCED MR IMAGING WITH COMPRESSED SENSING RECONSTRUCTION 审中-公开
标题翻译：动态对比增强MR成像与压缩感知重建
公开(公告)号：WO2011161566A1
公开(公告)日：2011-12-29
申请号：PCT/IB2011/052364
申请日：2011-05-30
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , DONEVA, Mariya, Ivanova
发明人： BOERNERT, Peter , DONEVA, Mariya, Ivanova
IPC分类号： G01N24/08 , G01R33/54 , G01R33/561 , G01R33/56 , G01R33/563 , G01R33/48
CPC分类号： G06T5/007 , G01N24/08 , G01R33/4828 , G01R33/5601 , G01R33/5607 , G01R33/5611 , G01R33/5615 , G01R33/56308 , G01R33/5635
摘要： The present invention relates to a method of performing dynamic contrast enhanced magnetic resonance imaging of an object (10) with signal separation for water and fat, the method comprising acquiring magnetic resonance datasets in the k-space using Dixon acquisition in a chemical shift encoding space and dynamic time resolution in a dynamic time space, wherein the dataset acquisition is performed employing undersampling, wherein the method further comprises: applying a compressed sensing reconstruction technique in the k-space, the chemical shift encoding space and the dynamic time space, said compressed sensing reconstruction resulting in reconstructed datasets, - performing Dixon reconstruction on the reconstructed datasets and dynamic contrast analysis on the Dixon reconstructed datasets.
摘要翻译：本发明涉及对具有水分和脂肪信号分离的物体（10）进行动态对比度增强磁共振成像的方法，所述方法包括使用在化学位移编码空间中的狄克逊采集在k空间中获取磁共振数据集以及在动态时间空间中的动态时间分辨率，其中使用欠采样执行所述数据集采集，其中所述方法还包括：在所述k空间，所述化学位移编码空间和所述动态时间空间中应用压缩感测重建技术，所述压缩感测重建导致重构数据集， - 对重构数据集进行Dixon重建，并对Dixon重建数据集进行动态对比分析。

10. 发明申请

WO2010113122A1 SAR HOTSPOT REDUCTION BY TEMPORAL AVERAGING IN PARALLEL TRANSMISSION MRI 审中-公开
标题翻译：通过时间平均在平行传输中减少SAR值
公开(公告)号：WO2010113122A1
公开(公告)日：2010-10-07
申请号：PCT/IB2010/051399
申请日：2010-03-31
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , GRAESSLIN, Ingmar , SCHWESER, Ferdinand , BOERNERT, Peter , HARVEY, Paul Royston
发明人： GRAESSLIN, Ingmar , SCHWESER, Ferdinand , BOERNERT, Peter , HARVEY, Paul Royston
IPC分类号： G01R33/3415
CPC分类号： G01R33/3415 , G01R33/288 , G01R33/543 , G01R33/5612 , G01R33/5659
摘要： A magnetic resonance sequence includes a repetitively applied radiofrequency B 1 pulse capable of causing a specific absorption rate (SAR) hot spot. The composition of the repetitive B 1 pulse is varied to generate versions of the repetitive B 1 pulse such that the SAR hot spot changes locations with subsequent applications of the repetitive B 1 pulse. To generate versions of the B 1 pulse, a pilot scan is performed to generate a patient model. A simulation of the SAR response to each of the versions of the repetitive B 1 pulse is performed to determine the location of SAR hot spot(s). A plurality of versions of the repetitive B 1 pulse is selected to be used in the magnetic resonance sequence.
摘要翻译：磁共振序列包括能够引起比吸收率（SAR）热点的重复施加的射频B1脉冲。改变重复B1脉冲的组成以产生重复B1脉冲的形式，使得SAR热点随后应用重复的B1脉冲而改变位置。为了生成B1脉冲的版本，执行导频扫描以产生患者模型。执行对每个重复B1脉冲版本的SAR响应的模拟，以确定SAR热点的位置。选择在磁共振序列中使用多个版本的重复B1脉冲。

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