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1. 发明申请

WO2010150209A1 A HYPERPOLARIZED CONTRAST AGENT DISPENSER FOR MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：用于磁共振成像的超高对比度对比剂分配器
公开(公告)号：WO2010150209A1
公开(公告)日：2010-12-29
申请号：PCT/IB2010/052864
申请日：2010-06-23
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LEUSSLER, Christoph , BOERNERT, Peter , WIRTZ, Daniel , DAVID, Bernd , EGGERS, Holger , KEUPP, Jochen , OVERWEG, Johannes, Adrianus , ECKART, Rainer
发明人： LEUSSLER, Christoph , BOERNERT, Peter , WIRTZ, Daniel , DAVID, Bernd , EGGERS, Holger , KEUPP, Jochen , OVERWEG, Johannes, Adrianus , ECKART, Rainer
IPC分类号： A61M16/10
CPC分类号： A61M16/10 , A61B5/055 , A61M16/14 , A61M2016/0015 , A61M2202/066
摘要： A dispenser (132), a magnetic resonance imaging system (100), and a method for using hyperpolarized contrast agent (304) during a magnetic resonance imaging examination. The dispenser comprises an attachment component (136) for a face piece (138). The face piece is adapted for receiving the surface of a subject (114) such that when the subject inhales hyperpolarized contrast agent enters the respiratory system of the subject. The dispenser further comprises a reservoir (300) adapted for receiving the hyperpolarized contrast agent. The dispenser further comprises a gas flow (406) tube connected to the attachment component and a vaporizer (406, 408, 412, 510, 602, 606) for vaporizing the hyperpolarized contrast agent in the gas flow tube into a hyperpolarized vapor. The dispenser further comprises a controller (402) for controlling when the vaporizer vaporizes the hyperpolarized contrast agent.
摘要翻译：分配器（132），磁共振成像系统（100）以及在磁共振成像检查期间使用超极化造影剂（304）的方法。分配器包括用于面件（138）的附接部件（136）。面部件适于接纳被检体（114）的表面，使得当受试者吸入超极化造影剂进入受试者的呼吸系统时。分配器还包括适于接收超极化造影剂的贮存器（300）。分配器还包括连接到附接部件的气流（406）管和用于将气体流管中的超极化造影剂蒸发成超极化蒸气的蒸发器（406,408,412,510,602,606）。分配器还包括控制器（402），用于控制蒸发器何时蒸发超极化造影剂。

2. 发明申请

WO2010082150A1 CATHETER BEING USABLE IN A MAGNETIC RESONANCE IMAGING SYSTEM 审中-公开
标题翻译：导管可用于磁共振成像系统
公开(公告)号：WO2010082150A1
公开(公告)日：2010-07-22
申请号：PCT/IB2010/050082
申请日：2010-01-11
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WEISS, Steffen , LIPS, Oliver , KRUEGER, Sascha , DAVID, Bernd
发明人： WEISS, Steffen , LIPS, Oliver , KRUEGER, Sascha , DAVID, Bernd
IPC分类号： A61M25/00 , G01R33/28
CPC分类号： A61M25/0021 , A61B18/1492 , A61B2018/00023 , A61B2018/00029 , A61B2018/00744 , A61B2034/2051 , A61B2090/374 , A61B2090/3954 , A61M25/0082 , A61M25/10 , A61M2025/0166 , G01R33/287
摘要： The present invention relates toa catheter (2) for applying energy to an object (6) and a magnetic resonance imaging system (1) for localizing the catheter (2). The catheter (2) comprises an energyapplication element for applying energy to the object (6), and a cavity for providing a magnetic resonance fluid from which magnetic resonance signals generated by the magnetic resonance imaging system (1) arereceivable, wherein the cavity is adapted for providing a cooling fluid as the magnetic resonance fluidfor cooling the energy application element. The catheter (2) comprises further a tracking coil (15) for tracking the catheter (2), wherein the trackingcoil (15) is adapted to receive the magnetic resonance signals from the magnetic resonance fluid. Thus, the magnetic resonance fluid fulfils at least twofunctions, providing magnetic resonance signals for tracking the catheter (2) and cooling the energy application element.
摘要翻译：本发明涉及用于对物体（6）施加能量的导管（2）和用于定位导管（2）的磁共振成像系统（1）。导管（2）包括用于向物体（6）施加能量的能量施加元件，以及用于提供磁共振流体的空腔，由磁共振成像系统（1）产生的磁共振信号可从该磁共振流体中获得，其中腔适配用于提供作为用于冷却能量施加元件的磁共振流体的冷却流体。导管（2）还包括用于跟踪导管（2）的跟踪线圈（15），其中跟踪线圈（15）适于从磁共振流体接收磁共振信号。因此，磁共振流体实现至少两个功能，提供用于跟踪导管（2）并且冷却能量施加元件的磁共振信号。

3. 发明申请

WO2009004548A3 TRANSMISSION CABLE FOR USE IN RADIO-FREQUENCY MAGNETIC OR ELECTRICAL FIELDS 审中-公开
公开(公告)号：WO2009004548A3
公开(公告)日：2009-01-08
申请号：PCT/IB2008/052589
申请日：2008-06-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KRUEGER, Sascha , DAVID, Bernd , LIPS, Oliver , WEISS, Steffen , WIRTZ, Daniel
发明人： KRUEGER, Sascha , DAVID, Bernd , LIPS, Oliver , WEISS, Steffen , WIRTZ, Daniel
IPC分类号： G01R33/28
摘要： A transmission cable for use in an elongate medical device (420) such as a catheter, guide wire, etc., wherein the transmission cable is capable of being switched to an MR-safe mode only when necessary, while retaining its optimal electrical transmission properties otherwise, is disclosed herein. The transmission cable comprises a transmission line including at least two electrically conductive line segments (104a, 104b) separated by a non-conductive gap (106a), a bridging unit comprising at least one electrically conductive bridge segment (108a) capable of bridging the non-conductive gap, and a switching unit (112) arranged to move the bridging unit and/or the transmission line to electrically connect the two line segments by closing the non-conductive gap using the bridge segment or to electrically disconnect the two line segments by opening the non-conductive gap.

4. 发明申请

WO2007149749A2 MULTI-TUBE IMAGING SYSTEM SCATTER CORRECTION 审中-公开
标题翻译：多管成像系统散热器校正
公开(公告)号：WO2007149749A2
公开(公告)日：2007-12-27
申请号：PCT/US2007071095
申请日：2007-06-13
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS CORP , DAVID BERND , GRASS MICHAEL , LEWALTER ASTRID FATOU , PIETIG RAINER
发明人： DAVID BERND , GRASS MICHAEL , LEWALTER ASTRID FATOU , PIETIG RAINER
IPC分类号： A61B6/03
CPC分类号： G01T1/2985 , A61B6/032 , A61B6/4014 , A61B6/483 , A61B6/5282 , A61B6/583
摘要： A computed tomography reconstruction method includes concurrently emitting radiation from at least two x-ray sources (14), switching the output state of each of the at least two x-ray sources (14) within a plurality of respective cross scatter sampling intervals (50, 52, 54, 56) and detecting with a corresponding one of the sets of detectors (24) cross scatter radiation emitted by the other at least two x-ray sources (14), wherein the cross scatter sampling intervals are angularly spaced over a plurality of frames to allow the at least two x-ray sources (14) to concurrently emit radiation throughout at least one frame, deriving scatter correction data for each set of detectors (24) from corresponding cross scatter samples, scatter correcting the projection data with corresponding scatter correction data, and reconstructing the scatter corrected projection data to generate at least one image.
摘要翻译：计算机断层摄影重建方法包括同时从至少两个x射线源（14）发射辐射，在多个相应的交叉散射采样间隔（50）内切换所述至少两个x射线源（14）中的每一个的输出状态，52,54,56），并且用所述检测器组（24）中的对应的一组检测由所述另外的至少两个x射线源（14）发射的散射辐射，其中所述交叉散射采样间隔在多个帧以允许至少两个x射线源（14）同时在至少一个帧中发射辐射，从相应的交叉散射样本导出每组检测器（24）的散射校正数据，利用对应的散射校正数据，以及重建散射校正投影数据以生成至少一个图像。

5. 发明申请

WO2003077277A1 A DEVICE FOR GENERATING X-RAYS HAVING A LIQUID METAL ANODE 审中-公开
标题翻译：用于产生具有液体金属阳极的X射线的装置
公开(公告)号：WO2003077277A1
公开(公告)日：2003-09-18
申请号：PCT/IB2003/000798
申请日：2003-02-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , HARDING, Geoffrey , DAVID, Bernd , THRAN, Axel , SCHLOMKA, Jens, P.
发明人： HARDING, Geoffrey , DAVID, Bernd , THRAN, Axel , SCHLOMKA, Jens, P.
IPC分类号： H01J35/08
CPC分类号： H01J35/08 , H01J2235/082 , H01J2235/1262
摘要： The invention relates to a device for generating X-rays (31). The device has a source (5) for emitting electrons (27) accommodated in a vacuum space (3). The X-rays are emitted by a liquid metal as a result of the incidence ofthe electrons. The liquid metal flows through a constriction (13) where the electrons emitted by the source impinge upon the liquid metal. The constriction is bounded by a thin window (23), which is made from a material which is transparent to electrons and X-rays and which separates the liquid metal in the constriction from the vacuum space, and by a wall (25) opposite to the window. According to the invention, the wall (25) has a profile (p) which matches a profile (p') which the window (23) has,during operation, as a result of a deformation of the window caused by a pressure of the liquid metal in the constriction (13). Thus, it is achieved that the constriction has a predetermined intended cross-sectional area, and a decrease of the flow velocity and an accompanying excessive increase of the pressure at the location of the deformation of the window are prevented.
摘要翻译：本发明涉及一种用于产生X射线的装置（31）。该装置具有用于发射容纳在真空空间（3）中的电子（27）的源（5）。由于电子的入射，X射线被液态金属发射。液体金属流过收缩部（13），其中由源发射的电子撞击液态金属。狭缝由薄的窗口（23）限定，薄的窗口（23）由对电子和X射线透明的材料制成，并且将收缩部中的液体金属与真空空间分开，并且通过与窗户。根据本发明，壁（25）具有与窗口（23）具有的轮廓（p'）匹配的轮廓（p），在操作期间，由于窗口（23）的压力导致的窗口的变形收缩部（13）中的液态金属。因此，实现了收缩具有预定的预期横截面积，并且防止了流动速度的降低和伴随着窗口变形位置处压力的过度增加。

6. 发明申请

WO2003001556A1 X-RAY SOURCE PROVIDED WITH A LIQUID METAL TARGET 审中-公开
标题翻译： X射线源由液体金属靶提供
公开(公告)号：WO2003001556A1
公开(公告)日：2003-01-03
申请号：PCT/IB2002/002374
申请日：2002-06-20
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS CORPORATE INTELLECTUAL PROPERTY GMBH , HARDING, Geoffrey , DAVID, Bernd , ECKART, Rainer, W. , SCHLOMKA, Jens, P.
发明人： HARDING, Geoffrey , DAVID, Bernd , ECKART, Rainer, W. , SCHLOMKA, Jens, P.
IPC分类号： H01J35/08
CPC分类号： H01J35/08 , H01J2235/082
摘要： The invention relates to an X-ray source which is provided with a liquid metal target (3) which flows through a system of ducts (6) and is conducted through a duct section (8) whose flow cross-section is reduced relative to that of the system of ducts. The X-ray source is characterized notably in that there is provided a pressure source (12, 13; 14; 16) for acting on the liquid metal target (3) in such a manner that in the operating condition of the X-ray source the pressure in the liquid metal target (3) at the area of the reduced flow cross-section equals essentially a selectable reference value (Ps) or remains essentially in a pressure range between selectable limit values (Ps1, Ps2) of the pressure. A comparatively small thickness of a window which is transparent to an electron beam can thus be realized in conjunction with a comparatively high flow speed, that is, without having to accept the risk of cavitations. The invention also relates to an X-ray apparatus provided with an X-ray source of this kind.
摘要翻译：本发明涉及一种具有液体金属靶（3）的X射线源，该液体金属靶（3）流过管道（6）的系统，并通过导管部分（8）传导，该管道部分（8）的流动横截面相对于的管道系统。 X射线源的特征在于，提供了一个用于作用在液态金属靶（3）上的压力源（12,13; 14; 16），使得在X射线源的运行状态在流动截面减小的区域中的液态金属靶（3）中的压力基本上等于可选择的参考值（Ps），或者基本上保持在压力的可选极限值（Ps1，Ps2）之间的压力范围内。因此，与电子束透明的窗口相对较小的厚度可以结合较高的流速来实现，即不必接受空化的风险。本发明还涉及具备这种X射线源的X射线装置。

7. 发明申请

WO2011080697A2 DYNAMIC NUCLEAR POLARIZATION APPARATUS 审中-公开
标题翻译：动态核极化装置
公开(公告)号：WO2011080697A2
公开(公告)日：2011-07-07
申请号：PCT/IB2010/056092
申请日：2010-12-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LEUSSLER, Christoph , WIRTZ, Daniel , BOERNERT, Peter , KEUPP, Jochen , EGGERS, Holger , DAVID, Bernd , OVERWEG, Johannes, Adrianus , ECKART, Rainer
发明人： LEUSSLER, Christoph , WIRTZ, Daniel , BOERNERT, Peter , KEUPP, Jochen , EGGERS, Holger , DAVID, Bernd , OVERWEG, Johannes, Adrianus , ECKART, Rainer
IPC分类号： G01R33/28
CPC分类号： G01R33/62 , G01R33/282 , G01R33/5601 , G01R33/5605 , G01R33/5608 , G01R33/56366 , G01R33/56383
摘要： The invention relates to a dynamic nuclear polarization apparatus (116) for continuous provision of hyperpolarized samples (114) comprising dynamically nuclear polarized nuclear spins, the apparatus (116) comprising a polarization region (106) for polarization of said nuclear spins resulting in said hyperpolarized samples, wherein the apparatus (116) further comprises: a cryostat (102) for cooling the samples (114) in the polarization region (106), a magnet (100) for providing a magnetic field to the cooled samples in the polarization region (106), a radiation source (112) for concurrently to the magnetic field provision providing a nuclear polarizing radiation to the polarization region (106) for receiving the hyperpolarized samples, a sample transport system (104) for continuously receiving unpolarized samples (114), transporting the unpolarized samples to the polarization region (106) for nuclear spin polarization and providing the resulting hyperpolarized samples (114).
摘要翻译：本发明涉及用于连续提供包含动态核极化核自旋的超极化样本（114）的动态核极化装置（116），所述装置（116）包括用于所述核自旋的极化的偏振区域（106），导致所述超极化样品，其中所述设备（116）还包括：用于冷却所述偏振区域（106）中的样品（114）的低温恒温器（102），用于向所述偏振区域中的所述冷却样品提供磁场的磁体（100） 106），用于与磁场提供同时提供用于接收超极化样本的偏振区域（106）的核偏振辐射的辐射源（112），用于连续接收非偏振样本（114）的样本传输系统（104）将非偏振样品运送到用于核自旋极化的偏振区域（106），并提供所得到的超极化样品（114）。

8. 发明申请

WO2009081361A1 ELECTROMAGNET WITH LAMINATED FERROMAGNETIC CORE AND SUPERCONDUCTING FILM FOR. SUPPRESSING EDDY MAGNETIC FIELD 审中-公开
标题翻译：具有层压铁磁芯和超导膜的电磁体。抑制EDDY磁场
公开(公告)号：WO2009081361A1
公开(公告)日：2009-07-02
申请号：PCT/IB2008/055445
申请日：2008-12-19
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , OVERWEG, Johannes Adrianus , TIMINGER, Holger , DAVID, Bernd
发明人： OVERWEG, Johannes Adrianus , TIMINGER, Holger , DAVID, Bernd
IPC分类号： G01R33/381 , G01R33/385 , H01B12/06 , H01B12/16 , H01F7/11
CPC分类号： G01R33/381 , G01R33/385 , H01F3/02 , H01F7/202 , H01F27/34 , H01F2027/348
摘要： An electromagnet comprises: a ferromagnetic core (50, 72); electrically conductive windings (34, 76) disposed around the ferromagnetic core such that current flowing in the windings magnetizes the ferromagnetic core; and a superconducting film (60, 80, 82) arranged to support eddy current cancelling supercurrent that suppresses eddy current formation in the ferromagnetic core when the windings magnetize the ferromagnetic core. A magnetic resonance scanner embodiment includes a main magnet (20) generating a static magnetic field and a magnetic field gradient system (30) with a plurality of said electromagnets (34, 50, 60) configured to superimpose selected magnetic field gradients on the static magnetic field.
摘要翻译：电磁铁包括：铁磁芯（50,72）; 设置在铁磁芯周围的导电绕组（34,76），使得在绕组中流动的电流使铁磁芯磁化; 以及布置成支撑涡流消除超导电流的超导膜（60,80,82），当绕组磁化铁磁芯时，其抑制铁磁芯中的涡流形成。磁共振扫描器实施例包括产生静磁场的主磁体（20）和具有多个所述电磁体（34,50,60）的磁场梯度系统（30），所述多个所述电磁体被配置为将选定的磁场梯度叠加在静磁领域。

9. 发明申请

WO2009004548A2 TRANSMISSION CABLE FOR USE IN RADIO-FREQUENCY MAGNETIC OR ELECTRICAL FIELDS 审中-公开
标题翻译：用于无线电频率电磁场的变速电缆
公开(公告)号：WO2009004548A2
公开(公告)日：2009-01-08
申请号：PCT/IB2008052589
申请日：2008-06-27
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS INTELLECTUAL PROPERTY , KRUEGER SASCHA , DAVID BERND , LIPS OLIVER , WEISS STEFFEN , WIRTZ DANIEL
发明人： KRUEGER SASCHA , DAVID BERND , LIPS OLIVER , WEISS STEFFEN , WIRTZ DANIEL
IPC分类号： A61M25/09
CPC分类号： G01R33/36 , A61B18/14 , A61B2018/00178 , A61B2090/374 , A61N1/086 , G01R33/287 , G01R33/288 , G01R33/3664
摘要： A transmission cable for use in an elongate medical device (420) such as a catheter, guide wire, etc., wherein the transmission cable is capable of being switched to an MR-safe mode only when necessary, while retaining its optimal electrical transmission properties otherwise, is disclosed herein. The transmission cable comprises a transmission line including at least two electrically conductive line segments (104a, 104b) separated by a non-conductive gap (106a), a bridging unit comprising at least one electrically conductive bridge segment (108a) capable of bridging the non-conductive gap, and a switching unit (112) arranged to move the bridging unit and/or the transmission line to electrically connect the two line segments by closing the non-conductive gap using the bridge segment or to electrically disconnect the two line segments by opening the non-conductive gap.
摘要翻译：一种用于诸如导管，导丝等细长医疗设备（420）的传输电缆，其中传输电缆仅在必要时能够切换到MR安全模式，同时保持其最佳的电传输特性否则，在此公开。传输电缆包括传输线，传输线包括由非导电间隙（106a）隔开的至少两个导电线段（104a，104b）;桥接单元，包括至少一个导电桥段（108a）以及开关单元（112），其布置成使桥接单元和/或传输线移动以通过使用桥接段闭合非导电间隙来电连接两个线段，或者通过打开非导电间隙。

10. 发明申请

WO2005034167A2 METHOD OF MANUFACTURING A WINDOW TRANSPARENT FOR ELECTRONS OF AN ELECTRON BEAM, IN PARTICULAR OF AN X-RAY SOURCE 审中-公开
标题翻译：制造电子束电子窗口透明度的方法，特别是X射线源
公开(公告)号：WO2005034167A2
公开(公告)日：2005-04-14
申请号：PCT/IB2004/051996
申请日：2004-10-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , FLISIKOWSKI, Peter , MEYS, Joachim , LESMEISTER, Werner , DAVID, Bernd, R. , BACHMANN, Peter, K.
发明人： FLISIKOWSKI, Peter , MEYS, Joachim , LESMEISTER, Werner , DAVID, Bernd, R. , BACHMANN, Peter, K.
IPC分类号： H01J35/00
CPC分类号： H01J33/04 , G11B20/1883 , G11B2020/10944 , G11B2020/1288 , G11B2020/1896 , G11B2220/20 , G11B2220/2541 , H01J5/18 , H01J9/24 , H01J2235/082 , H01J2235/18
摘要： The present invention relates to a method of manufacturing a window transparent for electrons of an electron beam (E), in particular of an X-ray source. In order to enable a less costly and elaborate manufacture of such a window and in order to prevent unwanted sharp edges in a window area which may damage the window foil (2), a method is proposed comprising the steps of providing on a surface (11) of a carrier element (1) to which a window foil (2) shall be a fixed a receiving area (13, 16) for receiving a soldering material (3) used for fixing said window foil (2) to said carrier element (1), said carrier element (1) comprising a through hole (12) for the transmission of said electrons (E), covering said surface (11) having said receiving area (12) with a soldering material (3) such that substantially only said receiving area (13, 16) is filled with soldering material (3), placing said window foil (2) on top of said surface (11) and heating said soldering material (3) for fixing said window foil (2) to said surface (11).
摘要翻译：本发明涉及一种制造电子束（E），特别是X射线源的电子透明窗口的方法。为了能够实现这种窗口的成本更低且更精细的制造，并且为了防止可能损坏窗帘（2）的窗口区域中的不必要的尖锐边缘，提出了一种方法，其包括以下步骤：在表面（11 （1）的固定接收区域（13,16），用于接收用于将所述窗口箔（2）固定到所述载体元件（2）的焊接材料（3）的载体元件（1） 1），所述载体元件（1）包括用于传输所述电子（E）的通孔（12），用焊接材料（3）覆盖具有所述接收区域（12）的所述表面（11），使得基本上仅所述接收区域（13,16）填充有焊接材料（3），将所述窗口箔（2）放置在所述表面（11）的顶部上，并加热所述焊接材料（3）以将所述窗户箔（2）固定到所述表面（11）。

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