专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06539264B1 Percutaneous electrical therapy system with sharp point protection 失效
标题翻译：经皮电疗治疗系统具有尖锐保护
公开(公告)号：US06539264B1
公开(公告)日：2003-03-25
申请号：US09451547
申请日：1999-12-01
申请人： Jon M. Bishay , Paul Leonard , Kent W. Leyde
发明人： Jon M. Bishay , Paul Leonard , Kent W. Leyde
IPC分类号： A61N104
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： A percutaneous electrical therapy system includes sharp point protection. In one embodiment, the system includes a control unit; an electrode assembly adapted to deliver electrical therapy to a patient, where the electrode assembly has an electrode electrically connectable to the control unit, the electrode having a sharp point at a distal end adapted to be inserted into the patient's tissue; and a sharp point protection assembly operable with the electrode assembly for reducing the risk of unintended exposure to the electrode's point. The system can also include an electrode assembly and sharp point protection assembly for a percutaneous electrical therapy system, as described above, apart from the control unit. In another embodiment, a method of performing percutaneous electrical therapy can include providing an electrode assembly having an electrode, the electrode having a sharp point at a distal end; inserting the sharp point of the electrode into a patient's tissue without exposing the sharp point to anyone but the patient; and applying an electrical signal to the electrode from a control unit.
摘要翻译：经皮电疗系统包括尖锐点保护。在一个实施例中，系统包括控制单元; 电极组件，其适于将电疗法递送到患者，其中所述电极组件具有可电连接到所述控制单元的电极，所述电极在适于插入患者组织的远端具有尖锐点; 以及可与电极组件一起操作的尖锐点保护组件，用于减少意外暴露于电极点的风险。除了控制单元之外，系统还可以包括用于经皮电疗系统的电极组件和尖锐点保护组件，如上所述。在另一个实施例中，执行经皮电疗法的方法可以包括提供具有电极的电极组件，所述电极在远端具有尖锐点; 将电极的尖锐点插入病人的组织中，而不会将尖锐点暴露于除病人之外的任何人; 以及从控制单元向电极施加电信号。

2. 发明授权

US06516226B1 Percutaneous electrical therapy system for minimizing electrode insertion discomfort 失效
标题翻译：用于尽量减少电极插入不适的经皮电疗系统
公开(公告)号：US06516226B1
公开(公告)日：2003-02-04
申请号：US09452510
申请日：1999-12-01
申请人： Jon M. Bishay , Paul Leonard
发明人： Jon M. Bishay , Paul Leonard
IPC分类号： A61N118
CPC分类号： A61N1/0551 , A61N1/36017 , A61N1/36021 , A61N1/375 , Y10S128/907
摘要： In a preferred embodiment, a percutaneous electrical therapy system includes a control unit; an electrode electrically connected to the control unit to deliver electrical therapy to a patient, the electrode comprising a sharp point at a distal end adapted to be inserted into a patient's tissue at an electrode insertion point; and an electrode insertion pain reducer adapted to reduce pain experienced by the patient during insertion of the electrode into the patient's tissue. Both the electrode and electrode insertion pain reducer may be located apart from the control unit.
摘要翻译：在优选实施例中，经皮电疗系统包括控制单元; 电连接到所述控制单元以将电疗法递送到患者的电极，所述电极包括在远端处的尖锐点，其适于在电极插入点处插入患者组织中; 以及电极插入式疼痛减轻器，其适于减少将电极插入患者组织期间患者经历的疼痛。电极和电极插入疼痛减少器都可以与控制单元分开。

3. 发明授权

US06522927B1 Electrode assembly for a percutaneous electrical therapy system 失效
标题翻译：用于经皮电疗治疗系统的电极组件
公开(公告)号：US06522927B1
公开(公告)日：2003-02-18
申请号：US09451800
申请日：1999-12-01
申请人： Jon M. Bishay , Paul Leonard
发明人： Jon M. Bishay , Paul Leonard
IPC分类号： A61N118
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： The invention is a percutaneous electrode assembly. In a preferred embodiment, the assembly includes a housing adapted to be mounted on a patient; an electrode disposed in the housing, the electrode having an sharp point at a distal end adapted to be inserted into a patient's tissue; an electrode actuator disposed in the housing and adapted to move the sharp point of the electrode out of the housing; and an electrode electrical connector adapted to electrically connect the electrode to a control unit to deliver electrical therapy to a patient. The invention is also a method of inserting a percutaneous electrode into a patient. In a preferred embodiment, the method includes the following steps: placing a housing on a patient; and moving at least part of an electrode out of the housing and into the patient and connecting the electrode electrically with a control unit cable, the moving and connecting steps being performed with a single user motion.
摘要翻译：本发明是经皮电极组件。在优选实施例中，组件包括适于安装在患者身上的壳体; 设置在所述壳体中的电极，所述电极在适于插入患者组织的远端具有尖锐点; 电极致动器，其设置在所述壳体中并且适于将所述电极的尖锐点移出所述壳体; 以及电极电连接器，其适于将电极电连接到控制单元以将电疗法递送给患者。本发明还是将经皮电极插入患者体内的方法。在优选实施例中，该方法包括以下步骤：将壳体放置在患者身上; 并且将电极的至少一部分移出壳体并进入患者体内，并将电极与控制单元电缆电连接，移动和连接步骤以单个用户运动进行。

4. 发明授权

US06549810B1 Percutaneous electrical therapy system with electrode depth control 失效
标题翻译：经皮电疗治疗系统，电极深度控制
公开(公告)号：US06549810B1
公开(公告)日：2003-04-15
申请号：US09452508
申请日：1999-12-01
申请人： Paul Leonard , Jon M. Bishay
发明人： Paul Leonard , Jon M. Bishay
IPC分类号： A61N105
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： A percutaneous electrical therapy system with electrode angle of entry control. In one embodiment, the system includes a control unit; an electrode assembly adapted to deliver electrical therapy to a patient, the electrode assembly including an electrode electrically connectable to the control unit, the electrode having a sharp point at a distal end adapted to be inserted into a patient's tissue; and an electrode depth control assembly adapted to control insertion of the electrode's point to a predetermined depth into the patient's tissue. The electrode depth control assembly can have a limit stop limiting length of travel of the electrode's point. The system can also include the percutaneous electrode and depth control assembly described above apart from the control unit. In another embodiment, a method of performing percutaneous electrical therapy includes providing an electrode assembly comprising an electrode, the electrode having a sharp point at a distal end; using an electrode depth control assembly to insert the sharp point of the electrode a predetermined depth into a patient's tissue; and applying an electrical signal to the electrode from a control unit.
摘要翻译：具有电极入口控制角度的经皮电疗系统。在一个实施例中，系统包括控制单元; 电极组件，其适于将电疗法递送到患者，所述电极组件包括可电连接到所述控制单元的电极，所述电极在适于插入患者组织的远端具有尖锐点; 以及电极深度控制组件，其适于控制将电极的点插入患者组织中的预定深度。电极深度控制组件可以具有极限停止限制电极点行程的长度。除了控制单元之外，该系统还可以包括上述的经皮电极和深度控制组件。在另一个实施例中，执行经皮电疗法的方法包括提供包括电极的电极组件，所述电极在远端具有尖锐点; 使用电极深度控制组件将电极的尖点插入患者组织中的预定深度; 以及从控制单元向电极施加电信号。

5. 发明授权

US06493592B1 Percutaneous electrical therapy system with electrode position maintenance 失效
标题翻译：经皮电疗治疗系统，电极位置维持
公开(公告)号：US06493592B1
公开(公告)日：2002-12-10
申请号：US09451795
申请日：1999-12-01
申请人： Paul Leonard , Jon M. Bishay
发明人： Paul Leonard , Jon M. Bishay
IPC分类号： A61N105
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： A percutaneous electrical therapy system with electrode position maintenance. In one embodiment, the system includes a control unit; an electrode electrically connectable to the control unit, the electrode having a sharp point at a distal end adapted to be inserted into a patient's tissue; and an inserted electrode holding mechanism adapted to hold the electrode in place after insertion of the sharp point of the electrode into the patient's tissue. In another embodiment, a method of providing electrical therapy can include inserting an electrode into a patient; using an inserted electrode holding mechanism to hold the inserted electrode in place in the patient; and applying an electrical signal to the electrode from a control unit.
摘要翻译：具有电极位置维护的经皮电疗治疗系统。在一个实施例中，系统包括控制单元; 电极，其可电连接到所述控制单元，所述电极在适于被插入患者组织的远端具有尖锐点; 以及插入的电极保持机构，其适于在将电极的尖锐点插入患者组织之后将电极保持在适当位置。在另一个实施例中，提供电疗法的方法可以包括将电极插入患者体内; 使用插入的电极保持机构将插入的电极保持在患者的适当位置; 以及从控制单元向电极施加电信号。

6. 发明授权

US06622051B1 Percutaneous electrical therapy system with electrode entry angle control 失效
标题翻译：具有电极入口角度控制的经皮电疗系统
公开(公告)号：US06622051B1
公开(公告)日：2003-09-16
申请号：US09452477
申请日：1999-12-01
申请人： Jon M. Bishay , Paul Leonard
发明人： Jon M. Bishay , Paul Leonard
IPC分类号： A61N100
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： A percutaneous electrical therapy system with electrode angle of entry control, wherein the system includes a control unit; an electrode electrically connectable to the control unit to deliver electrical therapy to a patient, the electrode having a sharp point at a distal end adapted to be inserted into a patient's tissue; and an electrode angle of insertion assembly controlling the electrode's angle of entry into the patient's tissue. The invention also includes the percutaneous electrode and electrode angle of insertion assembly described above apart from the control unit. The invention is also a method of performing percutaneous electrical therapy including the steps of: aligning an electrode assembly housing with a patient's tissue; inserting a sharp point of an electrode into the patient's tissue, the housing supporting the electrode during insertion to control the electrode's angle of insertion; and applying an electrical signal to the electrode from a control unit.
摘要翻译：一种具有电极入口控制角度的经皮电疗系统，其中所述系统包括控制单元; 电极，其可电连接到所述控制单元以将电疗法递送给患者，所述电极在适于被插入患者组织的远端具有尖锐点; 以及插入组件的电极角度，其控制电极进入患者组织的角度。本发明还包括除了控制单元之外的经皮电极和插入组件的电极角度。本发明还是一种执行经皮电疗法的方法，包括以下步骤：将电极组件壳体与患者组织对准; 将电极的尖锐点插入患者的组织中，所述壳体在插入期间支撑电极以控制电极的插入角度; 以及从控制单元向电极施加电信号。

7. 发明授权

US06560491B1 Percutaneous electrical therapy system providing electrode axial support 失效
标题翻译：经皮电疗系统提供电极轴向支撑
公开(公告)号：US06560491B1
公开(公告)日：2003-05-06
申请号：US09452663
申请日：1999-12-01
申请人： Paul Leonard , Jon M. Bishay
发明人： Paul Leonard , Jon M. Bishay
IPC分类号： A61N100
CPC分类号： A61N1/0551 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： The invention is a percutaneous electrical therapy system providing electrode axial stability during electrode insertion. In a preferred embodiment, the system includes a control unit; an electrode electrically connectable to the control unit to deliver electrical therapy to a patient, the electrode having a sharp point at a distal end adapted to be inserted into a patient's tissue; and an electrode insertion axial supporter adapted to provide axial support to the electrode during insertion of the electrode into the patient's tissue. The invention also includes an electrode and an electrode insertion axial supporter apart from the control unit.
摘要翻译：本发明是在电极插入期间提供电极轴向稳定性的经皮电疗系统。在优选实施例中，系统包括控制单元; 电极，其可电连接到所述控制单元以将电疗法递送给患者，所述电极在适于被插入患者组织的远端具有尖锐点; 以及电极插入轴向支撑件，其适于在将电极插入患者组织期间向电极提供轴向支撑。本发明还包括除了控制单元之外的电极和电极插入轴向支撑件。

8. 发明授权

US06556869B1 Electrode introducer for a percutaneous electrical therapy system 失效
标题翻译：用于经皮电疗治疗系统的电极引导器
公开(公告)号：US06556869B1
公开(公告)日：2003-04-29
申请号：US09451799
申请日：1999-12-01
申请人： Paul Leonard , Jon M. Bishay
发明人： Paul Leonard , Jon M. Bishay
IPC分类号： A61N118
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/375 , Y10S128/26 , Y10S128/907
摘要： A percutaneous electrode introducer, such as for use with a percutaneous electrical therapy system. In a preferred embodiment, the percutaneous electrode introducer includes a housing adapted to be held in a user's hand, the housing having an aperture at a distal end; an electrode disposed in the housing, the electrode having a sharp point at a distal end; and an actuator adapted to be operable by a user to move the electrode through the aperture and completely out of the housing to place the sharp point of the electrode beneath a patient's skin.
摘要翻译：经皮电极导引器，例如用于经皮电疗治疗系统。在优选实施例中，经皮电极导引器包括适于保持在使用者手中的壳体，所述壳体在远端具有孔; 设置在所述壳体中的电极，所述电极在远端具有尖锐点; 以及致动器，其适于由使用者操作以使所述电极移动通过所述孔并完全离开所述外壳，以将所述电极的尖锐点放置在患者皮肤下方。

9. 发明授权

US06549797B1 Electrode remover for a percutaneous electrical therapy system 失效
标题翻译：用于经皮电疗治疗系统的电极去除剂
公开(公告)号：US06549797B1
公开(公告)日：2003-04-15
申请号：US09451796
申请日：1999-12-01
申请人： Paul Leonard , Jon M. Bishay
发明人： Paul Leonard , Jon M. Bishay
IPC分类号： A61N102
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/375 , Y10S128/907
摘要： In a preferred embodiment, a percutaneous electrode remover includes a housing adapted to be held in a user's hand, the housing having an aperture at a distal end; and an actuator operable by a user to move a precutaneously inserted electrode through the aperture and completely into the housing.
摘要翻译：在优选实施例中，经皮电极去除器包括适于保持在使用者手中的壳体，所述壳体在远端具有孔; 以及致动器，其可由使用者操作以通过所述孔将预先插入的电极移动并完全进入所述壳体。

10. 发明授权

US09291628B2 Direct clone analysis and selection technology 有权
标题翻译：直接克隆分析和选择技术
公开(公告)号：US09291628B2
公开(公告)日：2016-03-22
申请号：US13809833
申请日：2011-07-13
申请人： Paul Leonard , Ivan Dimov , Richard O'Kennedy , Valerie Fitzgerald
发明人： Paul Leonard , Ivan Dimov , Richard O'Kennedy , Valerie Fitzgerald
IPC分类号： G01N33/53 , G01N33/68 , B01L3/00
CPC分类号： G01N33/54306 , B01L3/5085 , B01L3/50857 , B01L2300/0636 , B01L2300/0819 , B01L2300/12 , B01L2300/16 , C12Q1/6818 , C12Q1/6837 , G01N33/53 , G01N33/5302 , G01N33/545 , G01N33/569 , G01N33/68
摘要： The present invention describes a spatial addressing technique that uses a very high-density micro-pore array for high-throughput screening of biological interactions. The therapeutic, diagnostic and drug-discovery implications of being able to identify, select and characterize specific protein-protein, protein-DNA and/or protein-carbohydrate interactions from heterogeneous populations of millions (to billions) of cells is discussed. Importantly, this technique possesses the screening and selection capacity of current display-based screening systems (i.e., millions-billions) but with greater efficiency and shorter time.
摘要翻译：本发明描述了使用非常高密度的微孔阵列进行生物相互作用的高通量筛选的空间寻址技术。讨论了能够识别，选择和表征特定蛋白质蛋白质，蛋白质DNA和/或蛋白质 - 碳水化合物相互作用的治疗，诊断和药物发现影响，从数百万（至数十亿）细胞的异质群体。重要的是，该技术具有当前基于显示屏的筛选系统（即数百万亿）的筛选和选择能力，但具有更高的效率和更短的时间。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式