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1. 发明授权

US06539264B1 Percutaneous electrical therapy system with sharp point protection 失效
标题翻译：经皮电疗治疗系统具有尖锐保护
公开(公告)号：US06539264B1
公开(公告)日：2003-03-25
申请号：US09451547
申请日：1999-12-01
申请人： Jon M. Bishay , Paul Leonard , Kent W. Leyde
发明人： Jon M. Bishay , Paul Leonard , Kent W. Leyde
IPC分类号： A61N104
CPC分类号： A61N1/0551 , A61N1/0502 , A61N1/36017 , A61N1/36021 , A61N1/375
摘要： A percutaneous electrical therapy system includes sharp point protection. In one embodiment, the system includes a control unit; an electrode assembly adapted to deliver electrical therapy to a patient, where the electrode assembly has an electrode electrically connectable to the control unit, the electrode having a sharp point at a distal end adapted to be inserted into the patient's tissue; and a sharp point protection assembly operable with the electrode assembly for reducing the risk of unintended exposure to the electrode's point. The system can also include an electrode assembly and sharp point protection assembly for a percutaneous electrical therapy system, as described above, apart from the control unit. In another embodiment, a method of performing percutaneous electrical therapy can include providing an electrode assembly having an electrode, the electrode having a sharp point at a distal end; inserting the sharp point of the electrode into a patient's tissue without exposing the sharp point to anyone but the patient; and applying an electrical signal to the electrode from a control unit.
摘要翻译：经皮电疗系统包括尖锐点保护。在一个实施例中，系统包括控制单元; 电极组件，其适于将电疗法递送到患者，其中所述电极组件具有可电连接到所述控制单元的电极，所述电极在适于插入患者组织的远端具有尖锐点; 以及可与电极组件一起操作的尖锐点保护组件，用于减少意外暴露于电极点的风险。除了控制单元之外，系统还可以包括用于经皮电疗系统的电极组件和尖锐点保护组件，如上所述。在另一个实施例中，执行经皮电疗法的方法可以包括提供具有电极的电极组件，所述电极在远端具有尖锐点; 将电极的尖锐点插入病人的组织中，而不会将尖锐点暴露于除病人之外的任何人; 以及从控制单元向电极施加电信号。

2. 发明授权

US06662056B2 Cartridge for storing an electrode pad 有权
标题翻译：用于存放电极垫的墨盒
公开(公告)号：US06662056B2
公开(公告)日：2003-12-09
申请号：US09852431
申请日：2001-05-09
申请人： Anthony G. Picardo , Christine Janae , Thomas Solosko , Steven T. Mydynski , Ian G. MacDuff , Jon M. Bishay , Kent W. Leyde , Carlton B. Morgan
发明人： Anthony G. Picardo , Christine Janae , Thomas Solosko , Steven T. Mydynski , Ian G. MacDuff , Jon M. Bishay , Kent W. Leyde , Carlton B. Morgan
IPC分类号： A61N104
CPC分类号： A61N1/0472 , A61N1/046 , A61N1/048 , A61N1/0492 , A61N1/39 , A61N2001/37294
摘要： A cartridge is provided for storing one or more electrode pads such as a defibrillator electrode pad. The cartridge includes a housing having a rigid portion, a storage space disposed within the housing, and a storage-space opening that allows one to remove/insert the electrode pad or pads from/into the storage space. Because it has a housing with a rigid portion, such a cartridge can better protect one or more electrode pads from handling damage. Furthermore, one can construct the cartridge such that it is attachable to a medical device such as an AED. This allows an operator to carry or store the medical device, cartridge, and one or more electrode pads as a single unit. In addition, one can construct the cartridge such that the one or more electrode pads can be pre-connected to the medical device. This can eliminate connecting the one or more electrode pads to the medical device during an emergency.
摘要翻译：提供了用于存储一个或多个电极焊盘（例如除颤器电极焊盘）的盒。盒包括具有刚性部分的壳体，设置在壳体内的存储空间，以及允许将电极垫或垫从存储空间中移出/插入的存储空间开口。因为它具有刚性部分的壳体，所以这种盒可以更好地保护一个或多个电极垫不受处理损坏。此外，可以构造盒，使得其可附接到诸如AED的医疗装置。这允许操作者将医疗装置，药筒和一个或多个电极垫作为单个装置携带或储存。此外，可以构造盒，使得一个或多个电极垫可以预先连接到医疗装置。这可以在紧急情况期间消除将一个或多个电极焊盘连接到医疗装置。

3. 发明授权

US5951598A Electrode system 失效
标题翻译：电极系统
公开(公告)号：US5951598A
公开(公告)日：1999-09-14
申请号：US782990
申请日：1997-01-14
申请人： Jon M. Bishay , Kent W. Leyde , John F. Harris
发明人： Jon M. Bishay , Kent W. Leyde , John F. Harris
IPC分类号： A61N1/04
CPC分类号： A61B5/68 , A61N1/046 , A61N1/0492
摘要： This invention relates to medical electrode systems and, in particular, to a defibrillator electrode system for use with an automatic or semi-automatic external defibrillator (AED). This invention provides a medical electrode system with two electrodes. Each electrode has a flexible substrate with an adhesive surface; a conductor disposed on the substrate; and an electrode disposed on the substrate and electrically connected to the conductor. The electrode pads are each imprinted to show the proper placement of the electrode. Additionally, the medical electrode system may have the electrode pads adhered to a single removable releasing surface. The removable releasing surface may have a fold-line along a center axis between the two electrode pads, or alternatively may have perforations along the center axis. Ideally, the imprinting on each electrode pad can be interpreted by an AED operator without reviewing the imprinting of the other electrode pad.
摘要翻译：本发明涉及医用电极系统，特别涉及一种与自动或半自动外部除颤器（AED）一起使用的除颤器电极系统。本发明提供一种具有两个电极的医用电极系统。每个电极具有带有粘合剂表面的柔性基底; 设置在基板上的导体; 以及设置在基板上并电连接到导体的电极。每个印刷电极垫以显示电极的正确放置。另外，医疗电极系统可以具有粘附到单个可移除释放表面的电极垫。可拆卸的释放表面可以具有沿着两个电极焊盘之间的中心轴的折叠线，或者可以具有沿着中心轴线的穿孔。理想情况下，每个电极焊盘上的压印可以由AED操作员解释，而不会检查另一个电极焊盘的压印。

4. 发明授权

US09643019B2 Neurological monitoring and alerts 有权
公开(公告)号：US09643019B2
公开(公告)日：2017-05-09
申请号：US13026961
申请日：2011-02-14
申请人： Jason A. Higgins , Michael Bland , Kent W. Leyde , W. Douglas Sheffield , John F. Harris , David M. Himes
发明人： Jason A. Higgins , Michael Bland , Kent W. Leyde , W. Douglas Sheffield , John F. Harris , David M. Himes
IPC分类号： A61B5/04 , A61N1/372 , A61B5/00 , A61N1/00 , A61N1/05
CPC分类号： A61N1/37258 , A61B5/4094 , A61N1/00 , A61N1/0529 , G16H40/67
摘要： A system for providing alerts of neurological events occurring in a human subject is provided. The system includes: a monitoring module adapted to detect and sample a neurological signal; an event detection module coupled to the monitoring module for detecting one or more types of predetermined reportable events based on the detected neurological signal; and an alert module coupled to the event detection module, wherein upon the detection of a reportable event by the event detection module, said alert module selects a first alert contact from a plurality of contacts contained in a contact list, and generates a first alert communication to the first alert contact.

5. 发明授权

US08849390B2 Processing for multi-channel signals 有权
公开(公告)号：US08849390B2
公开(公告)日：2014-09-30
申请号：US12649098
申请日：2009-12-29
申请人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
发明人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
IPC分类号： A61B5/04 , A61B5/0476 , A61B5/00
CPC分类号： A61B5/0476 , A61B5/4094
摘要： Method and apparatus for improved processing for multi-channel signals. In an exemplary embodiment, an anomaly metric is computed for a multi-channel signal over a time window. The magnitude of the anomaly metric may be used to determine whether an anomaly is present in the multi-channel signal over the time window. In an exemplary embodiment, the anomaly metric may be a condition number associated with the singular values of the multi-channel signal over the time window, as further adjusted by the number of channels to produce a data condition number. Applications of the anomaly metric computation include the scrubbing of signal archives for epileptic seizure detection/prediction/counter-prediction algorithm training, pre-processing of multi-channel signals for real-time monitoring of bio-systems, and boot-up and/or adaptive self-checking of such systems during normal operation.

6. 发明授权

US08786624B2 Processing for multi-channel signals 有权
标题翻译：多通道信号处理
公开(公告)号：US08786624B2
公开(公告)日：2014-07-22
申请号：US12792582
申请日：2010-06-02
申请人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
发明人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
IPC分类号： G06T11/20 , G09G5/02 , G06F19/00 , G06F17/18
CPC分类号： A61B5/0476 , A61B5/076 , A61B5/4094 , A61B2560/0271 , G06K9/00536 , G06T11/206
摘要： Method and apparatus for improved processing for multi-channel signals. In an exemplary embodiment, an anomaly metric is computed for a multi-channel signal over a time window. The magnitude of the anomaly metric may be used to determine whether an anomaly is present in the multi-channel signal over the time window. In an exemplary embodiment, the anomaly metric may be a condition number associated with the singular values of the multi-channel signal over the time window, as further adjusted by the number of channels to produce a data condition number. Applications of the anomaly metric computation include the scrubbing of signal archives for epileptic seizure detection/prediction/counter-prediction algorithm training, pre-processing of multi-channel signals for real-time monitoring of bio-systems, and boot-up and/or adaptive self-checking of such systems during normal operation.
摘要翻译：用于改善多通道信号处理的方法和装置。在示例性实施例中，针对时间窗口上的多信道信号计算异常度量。可以使用异常度量的大小来确定在时间窗口上的多通道信号中是否存在异常。在示例性实施例中，异常度量可以是与时间窗口上的多信道信号的奇异值相关联的条件数，如通过产生数据条件数的信道数进一步调整的。异常度量计算的应用包括擦除用于癫痫发作检测/预测/反预测算法训练的信号档案，用于实时监测生物系统的多通道信号的预处理，以及启动和/或这种系统在正常运行期间的自适应自检。

7. 发明申请

US20110213222A1 Communication Error Alerting in an Epilepsy Monitoring System 有权
标题翻译：癫痫监测系统通信错误警报
公开(公告)号：US20110213222A1
公开(公告)日：2011-09-01
申请号：US13070333
申请日：2011-03-23
申请人： Kent W. Leyde , John F. Harris
发明人： Kent W. Leyde , John F. Harris
IPC分类号： A61B5/00 , A61B5/04
CPC分类号： A61B5/0476 , A61B5/0006 , A61B5/0031 , A61B5/4094 , A61B2560/0271 , A61M5/14276 , A61N1/36082 , A61N1/37247 , A61N1/37258 , A61N1/37282 , G06F19/3418
摘要： Systems and methods for monitoring neurological signals in a patient are provided. The system includes: an implantable sensor adapted to collect neurological signals; an implantable assembly configured to sample the neurological signals collected by the sensor; and a rechargeable communication device external to the patient's body, said communication device configured to wirelessly communicate with the implantable assembly and to transmit a communication error alert to a caregiver advisory device in the event of a communication error between the implantable assembly and the communication device.
摘要翻译：提供了用于监测患者神经信号的系统和方法。该系统包括：适于收集神经信号的可植入传感器; 植入式组件，被配置为对由所述传感器收集的神经信号进行采样; 以及在患者身体外部的可充电通信设备，所述通信设备被配置为与可植入组件进行无线通信，并且在可植入组件和通信设备之间发生通信错误的情况下向通知设备发送通信错误警报。

8. 发明申请

US20110172554A1 Patient Entry Recording in an Epilepsy Monitoring System 审中-公开
标题翻译：癫痫监测系统中的患者进入记录
公开(公告)号：US20110172554A1
公开(公告)日：2011-07-14
申请号：US13070357
申请日：2011-03-23
申请人： Kent W. Leyde , John F. Harris
发明人： Kent W. Leyde , John F. Harris
IPC分类号： A61B5/048
CPC分类号： A61B5/0476 , A61B5/0006 , A61B5/0031 , A61B5/4094 , A61B2560/0271 , A61M5/14276 , A61N1/36082 , A61N1/37247 , A61N1/37258 , A61N1/37282 , G06F19/3418
摘要： Systems and methods for monitoring a patient are provided. The system includes: an implantable sensor adapted to collect neurological signals; an implantable assembly configured to sample the neurological signals collected by the sensor; and a rechargeable external assembly configured to wirelessly receive the sampled neurological signals from the implantable assembly, said external assembly being further configured to record a patient entry in response to receiving an input from the patient. The method includes: collecting neurological signals with a sensor implanted in the patient; sampling the neurological signals collected by the sensor with an implantable assembly implanted in the patient; and transmitting the sampled neurological signals from the implantable assembly to a rechargeable external assembly external to the patient; and recording a patient entry in response to receiving an input from the patient.
摘要翻译：提供了用于监测患者的系统和方法。该系统包括：适于收集神经信号的可植入传感器; 植入式组件，被配置为对由所述传感器收集的神经信号进行采样; 以及可充电外部组件，其被配置为从所述可植入组件无线地接收所述取样的神经信号，所述外部组件还被配置为响应于接收到来自所述患者的输入而记录患者入口。该方法包括：用植入患者的传感器收集神经信号; 用植入患者的可植入组件对由传感器收集的神经信号进行采样; 以及将所述取样的神经信号从所述可植入组件传输到患者外部的可再充电外部组件; 以及响应于从患者接收到输入而记录患者入口。

9. 发明申请

US20100302270A1 Processing for Multi-Channel Signals 有权
标题翻译：多通道信号处理
公开(公告)号：US20100302270A1
公开(公告)日：2010-12-02
申请号：US12792582
申请日：2010-06-02
申请人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
发明人： Javier Ramón Echauz , David E. Snyder , Kent W. Leyde
IPC分类号： G06T11/20 , G09G5/02 , G06F19/00 , G06F17/18
CPC分类号： A61B5/0476 , A61B5/076 , A61B5/4094 , A61B2560/0271 , G06K9/00536 , G06T11/206
摘要： Method and apparatus for improved processing for multi-channel signals. In an exemplary embodiment, an anomaly metric is computed for a multi-channel signal over a time window. The magnitude of the anomaly metric may be used to determine whether an anomaly is present in the multi-channel signal over the time window. In an exemplary embodiment, the anomaly metric may be a condition number associated with the singular values of the multi-channel signal over the time window, as further adjusted by the number of channels to produce a data condition number. Applications of the anomaly metric computation include the scrubbing of signal archives for epileptic seizure detection/prediction/counter-prediction algorithm training, pre-processing of multi-channel signals for real-time monitoring of bio-systems, and boot-up and/or adaptive self-checking of such systems during normal operation.
摘要翻译：用于改善多通道信号处理的方法和装置。在示例性实施例中，针对时间窗口上的多信道信号计算异常度量。可以使用异常度量的大小来确定在时间窗口上的多通道信号中是否存在异常。在示例性实施例中，异常度量可以是与时间窗口上的多信道信号的奇异值相关联的条件数，如通过产生数据条件数的信道数进一步调整的。异常度量计算的应用包括擦除用于癫痫发作检测/预测/反预测算法训练的信号档案，用于实时监测生物系统的多通道信号的预处理，以及启动和/或这种系统在正常运行期间的自适应自检。

10. 发明申请

US20090171420A1 Housing for an Implantable Medical Device 有权
标题翻译：可植入医疗器械的住房
公开(公告)号：US20090171420A1
公开(公告)日：2009-07-02
申请号：US12343386
申请日：2008-12-23
申请人： David Brown , Christopher Genau , Kent W. Leyde , Shan Gaw , Jeffrey Stewart
发明人： David Brown , Christopher Genau , Kent W. Leyde , Shan Gaw , Jeffrey Stewart
IPC分类号： A61N1/05 , A61N1/08
CPC分类号： A61N1/3787 , A61N1/37223 , A61N1/375 , A61N1/3758
摘要： An implantable medical device having a concave ceramic housing component; a concave metal housing component attached to the ceramic housing component to form a hermetically sealed enclosure; and an electronic trans-housing magnetic flux component disposed within the enclosure. Another aspect of the invention provides an implantable medical device having a ceramic housing component; a metal housing component; a circumferential sealing member attached to a periphery of the ceramic housing component and to a periphery of the metal housing component to form a hermetically sealed enclosure; and an electronic trans-housing magnetic flux component disposed within the enclosure. Still another aspect of the invention provides an implantable medical device with a first metal housing component; a second metal housing component, the second metal housing component forming an opening; a ceramic housing component disposed in the opening, the first metal housing component, the second metal housing component and the ceramic housing component cooperating to form a hermetically sealed enclosure; and an electronic trans-housing magnetic flux component disposed within the enclosure.
摘要翻译：一种具有凹形陶瓷壳体部件的可植入医疗装置; 连接到陶瓷壳体部件的凹入金属壳体部件以形成密封的外壳; 以及设置在所述外壳内的电子跨壳体磁通部件。本发明的另一方面提供一种具有陶瓷壳体部件的可植入医疗装置; 金属外壳部件; 周向密封构件，其附接到陶瓷壳体部件的周边和金属壳体部件的周边，以形成密封的外壳; 以及设置在所述外壳内的电子跨壳体磁通部件。本发明的另一方面提供一种具有第一金属壳体部件的可植入医疗装置; 第二金属壳体部件，所述第二金属壳体部件形成开口; 设置在所述开口中的陶瓷壳体部件，所述第一金属壳体部件，所述第二金属壳体部件和所述陶瓷壳体部件协作以形成气密密封的壳体; 以及设置在所述外壳内的电子跨壳体磁通部件。

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