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1. 发明申请

US20080319309A1 System, Apparatus, and Method for Repreoducible and Comparable Flow Acquisitions 有权
标题翻译：可再生和可比流量采集的系统，仪器和方法
公开(公告)号：US20080319309A1
公开(公告)日：2008-12-25
申请号：US12096995
申请日：2006-12-08
申请人： Joerg Bredno , Alexandra Groth , Juergen Weese , Tom Bruijns , Peter M.J. Rongen , Roel Hermans , Heidrun Steinhauser
发明人： Joerg Bredno , Alexandra Groth , Juergen Weese , Tom Bruijns , Peter M.J. Rongen , Roel Hermans , Heidrun Steinhauser
IPC分类号： A61B5/055 , A61B6/00
CPC分类号： G01R33/5635 , A61B5/0275 , A61B5/0456 , A61B6/481 , A61B6/504 , A61B6/507 , A61B8/06 , A61M5/007 , A61M5/1723 , A61M2230/04 , G01R33/281 , G01R33/5601 , G06T7/0012 , G06T7/20 , G06T2207/30101
摘要： A system, apparatus and method are provided for measuring and removing the influence of pulsatility on contrast agent flow in a region of interest of a vascular system of a patient. Once the change of blood speed over the cardiac cycle is known (pulsatility), this influence is removed from acquired image sequence for outcome control such that “quasi-stationary”, regular flow acquisition is passed on to subsequent visualization and analysis processes. A contrast agent injector is also provided that simultaneously measures and uses ECG to inject a known contrast agent at a fixed point over the cardiac cycle or such that a known amount of contrast agent will arrive at a known time at a region of interest in the vasculature of a patient, thus controlling one of the main unwanted variables in an acquisition of blood flow sequences.
摘要翻译：提供了一种系统，装置和方法，用于测量和消除脉搏对患者血管系统感兴趣区域中造影剂流动的影响。一旦知道心搏周期的血液速度变化（脉动），这种影响就从获得的结果控制图像序列中消除，从而将“准静态”常规流量采集传递给随后的可视化和分析过程。还提供造影剂注射器，其同时测量并使用ECG在心脏周期上的固定点注入已知的造影剂，或使已知量的造影剂在脉管系统中的感兴趣区域的已知时间到达因此在获取血流序列时控制主要不需要的变量之一。

2. 发明申请

US20100074504A1 METHOD AND APPARATUS FOR ACQUIRING FUSION X-RAY IMAGES 审中-公开
标题翻译：用于获取融合X射线图像的方法和装置
公开(公告)号：US20100074504A1
公开(公告)日：2010-03-25
申请号：US12532459
申请日：2008-03-14
申请人： Antonius J.C. Bruijns , Ronaldus P.J. Hermans , Peter M.J. Rongen , Jarl J.P. Blijd , Herman Stegehuis , Joerg Bredno
发明人： Antonius J.C. Bruijns , Ronaldus P.J. Hermans , Peter M.J. Rongen , Jarl J.P. Blijd , Herman Stegehuis , Joerg Bredno
IPC分类号： G06K9/00 , G01N23/04
CPC分类号： A61B6/504 , A61B6/481 , A61B6/482 , A61B6/503 , A61B6/5235 , A61B6/541
摘要： A method for acquiring fusion images of a periodically moving body organ and an apparatus adapted to implement such method is described. In a preferred embodiment of the method, X-rays are irradiated to the body organ and a multiplicity of mask images is acquired by X-ray detection at a high image acquisition rate of at least 60 frames per second. Then, contrast medium is injected into vessels of the body organ and subsequently at least one contrast image of the body organ with the contrast medium included in the vessels is acquired by X-ray detection. A matching image from the multiplicity of mask images is determined which has been acquired at substantially the same stage of the movement of the body organ as the contrast image. By calculating the difference between the matching mask image and the at least one contrast image a subtraction image of the body organ can be obtained and displayed. Using different image acquisition rates during mask image acquisition and contrast image acquisition high quality subtraction images can be achieved while at the same time reducing the overall X-ray exposure dose.
摘要翻译：描述了一种用于获取定期移动的身体器官的融合图像的方法和适于实现这种方法的装置。在该方法的优选实施例中，将X射线照射到身体器官，并且通过以至少60帧/秒的高图像采集率的X射线检测获取多个掩模图像。然后，将造影剂注射到身体器官的血管中，随后通过X射线检测获得体内器官与包含在血管中的造影剂的至少一个对比图像。确定来自多个掩模图像的匹配图像，其在与对比图像的身体器官的移动的基本相同的阶段已被获取。通过计算匹配掩模图像和至少一个对比图像之间的差异，可以获得并显示身体器官的减影图像。在掩模图像采集和对比度图像采集期间使用不同的图像采集率可以实现高质量的减影图像，同时减少整个X射线曝光剂量。

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