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1. 发明申请

US20080319309A1 System, Apparatus, and Method for Repreoducible and Comparable Flow Acquisitions 有权
标题翻译：可再生和可比流量采集的系统，仪器和方法
公开(公告)号：US20080319309A1
公开(公告)日：2008-12-25
申请号：US12096995
申请日：2006-12-08
申请人： Joerg Bredno , Alexandra Groth , Juergen Weese , Tom Bruijns , Peter M.J. Rongen , Roel Hermans , Heidrun Steinhauser
发明人： Joerg Bredno , Alexandra Groth , Juergen Weese , Tom Bruijns , Peter M.J. Rongen , Roel Hermans , Heidrun Steinhauser
IPC分类号： A61B5/055 , A61B6/00
CPC分类号： G01R33/5635 , A61B5/0275 , A61B5/0456 , A61B6/481 , A61B6/504 , A61B6/507 , A61B8/06 , A61M5/007 , A61M5/1723 , A61M2230/04 , G01R33/281 , G01R33/5601 , G06T7/0012 , G06T7/20 , G06T2207/30101
摘要： A system, apparatus and method are provided for measuring and removing the influence of pulsatility on contrast agent flow in a region of interest of a vascular system of a patient. Once the change of blood speed over the cardiac cycle is known (pulsatility), this influence is removed from acquired image sequence for outcome control such that “quasi-stationary”, regular flow acquisition is passed on to subsequent visualization and analysis processes. A contrast agent injector is also provided that simultaneously measures and uses ECG to inject a known contrast agent at a fixed point over the cardiac cycle or such that a known amount of contrast agent will arrive at a known time at a region of interest in the vasculature of a patient, thus controlling one of the main unwanted variables in an acquisition of blood flow sequences.
摘要翻译：提供了一种系统，装置和方法，用于测量和消除脉搏对患者血管系统感兴趣区域中造影剂流动的影响。一旦知道心搏周期的血液速度变化（脉动），这种影响就从获得的结果控制图像序列中消除，从而将“准静态”常规流量采集传递给随后的可视化和分析过程。还提供造影剂注射器，其同时测量并使用ECG在心脏周期上的固定点注入已知的造影剂，或使已知量的造影剂在脉管系统中的感兴趣区域的已知时间到达因此在获取血流序列时控制主要不需要的变量之一。

2. 发明申请

US20080294038A1 Model-Based Flow Analysis and Visualization 审中-公开
标题翻译：基于模型的流量分析与可视化
公开(公告)号：US20080294038A1
公开(公告)日：2008-11-27
申请号：US12096436
申请日：2006-11-15
申请人： Juergen Weese , Alexandra Groth , Joerg Bredno , Tom Bruijns , Peter Rongen , Roel Hermans , Heidrun Steinhauser
发明人： Juergen Weese , Alexandra Groth , Joerg Bredno , Tom Bruijns , Peter Rongen , Roel Hermans , Heidrun Steinhauser
IPC分类号： A61B6/00 , G06G7/60
CPC分类号： A61B6/504 , A61B6/481 , A61B6/507 , G16H50/50
摘要： A system (900), method (100, 200) and apparatus (600, 700, 800) are provided for analyzing a blood flow in a vascular system from a dynamic diagnostic observation sequence (101) to determine blood flow parameters (112) for further determination of filters, replay speed and finally visualization of the replayed original and filtered sequences. A first embodiment (100) extracts features of the observation and uses these features to select an appropriate model from a database of pre-determined models of vascular system of interest which have associated parameters. These parameters are varied to create an instance of the model that best matches the original observation. A second embodiment (200) visualizes a replay of the original observation (101) and the observation (101′) predicted by the model to highlight differences therebetween. A third embodiment (800) provides filtering and control of the replay speed.
摘要翻译：提供了一种系统（900），方法（100,200）和装置（600,700,800），用于从动态诊断观察序列（101）分析血管系统中的血流，以确定血流参数（112）进一步确定滤镜，重放速度以及最终可重播的原始和过滤序列。第一实施例（100）提取观察的特征并且使用这些特征从具有相关参数的感兴趣的血管系统的预定模型的数据库中选择适当的模型。改变这些参数以创建与原始观察结果最匹配的模型实例。第二实施例（200）可视化通过模型预测的原始观察（101）和观察（101'）的重放以突出其间的差异。第三实施例（800）提供重放速度的过滤和控制。

3. 发明授权

US08340744B2 System, apparatus, and method for reproducible and comparable flow acquisitions 有权
标题翻译：用于可重复和可比较的流量采集的系统，装置和方法
公开(公告)号：US08340744B2
公开(公告)日：2012-12-25
申请号：US12096995
申请日：2006-12-08
申请人： Joerg Bredno , Alexandra Groth , Juergen Weese , Antonius Johannes Cornelius Bruijns , Peter Maria Johannes Rongen , Ronaldus Petrus Johannes Hermans , Heidrun Steinhauser
发明人： Joerg Bredno , Alexandra Groth , Juergen Weese , Antonius Johannes Cornelius Bruijns , Peter Maria Johannes Rongen , Ronaldus Petrus Johannes Hermans , Heidrun Steinhauser
IPC分类号： A61B6/00 , G06K9/00 , G06G7/58
CPC分类号： G01R33/5635 , A61B5/0275 , A61B5/0456 , A61B6/481 , A61B6/504 , A61B6/507 , A61B8/06 , A61M5/007 , A61M5/1723 , A61M2230/04 , G01R33/281 , G01R33/5601 , G06T7/0012 , G06T7/20 , G06T2207/30101
摘要： A system, apparatus and method are provided for measuring and removing the influence of pulsatility on contrast agent flow in a region of interest of a vascular system of a patient. Once the change of blood speed over the cardiac cycle is known (pulsatility), this influence is removed from acquired image sequence for outcome control such that “quasi-stationary”, regular flow acquisition is passed on to subsequent visualization and analysis processes. A contrast agent injector is also provided that simultaneously measures and uses ECG to inject a known contrast agent at a fixed point over the cardiac cycle or such that a known amount of contrast agent will arrive at a known time at a region of interest in the vasculature of a patient, thus controlling one of the main unwanted variables in an acquisition of blood flow sequences.
摘要翻译：提供了一种系统，装置和方法，用于测量和消除脉搏对患者血管系统感兴趣区域中造影剂流动的影响。一旦知道了心脏周期的血液速度变化（脉动），这种影响就从获得的结果控制图像序列中消除，从而使准静态，常规流动获取传递到随后的可视化和分析过程。还提供造影剂注射器，其同时测量并使用ECG在心脏周期上的固定点注入已知的造影剂，或使已知量的造影剂在脉管系统中的感兴趣区域的已知时间到达因此在获取血流序列时控制主要不需要的变量之一。

4. 发明授权

US09678222B2 Reducing trap effects in a scintillator by application of secondary radiation 有权
公开(公告)号：US09678222B2
公开(公告)日：2017-06-13
申请号：US12594958
申请日：2008-04-08
申请人： Rudolph M. Snoeren , Heidrun Steinhauser , Nicolaas J. Noordhoek , Matthias Simon
发明人： Rudolph M. Snoeren , Heidrun Steinhauser , Nicolaas J. Noordhoek , Matthias Simon
IPC分类号： G01T1/20
CPC分类号： G01T1/2018 , G01T1/20
摘要： A radiation detector device for detecting a primary radiation includes a scintillator which generates a converted primary radiation in response to incoming primary radiation and a photo detector for detecting the converted primary radiation. The radiation detector device further includes a secondary radiation source for irradiating the scintillator with a secondary radiation which has a wavelength different from a wavelength of the first radiation and which is capable of producing a spatially more uniform response of the scintillator to primary radiation.

5. 发明申请

US20100051816A1 DETERMINATION OF A SPATIAL GAIN DISTRIBUTION OF A SCINTILLATOR 有权
标题翻译：确定扫描仪空间增益分布
公开(公告)号：US20100051816A1
公开(公告)日：2010-03-04
申请号：US12594959
申请日：2008-04-09
申请人： Rudolph Maria Snoeren , Heidrun Steinhauser , Nicolaas Jan Noordhoek , Matthias Simon
发明人： Rudolph Maria Snoeren , Heidrun Steinhauser , Nicolaas Jan Noordhoek , Matthias Simon
IPC分类号： G01T1/20
CPC分类号： G01T1/2018 , G01T1/2928
摘要： A method for providing information about a spatial gain distribution of a scintillator for a primary radiation is provided which does not require the irradiation of the scintillator with the primary radiation. The method comprises the step of irradiating the scintillator with a secondary radiation for generating an image of a spatial secondary gain distribution of the scintillator for said second radiation. The spatial secondary gain distribution image corresponds to an image of the spatial primary gain distribution for the primary radiation. In an embodiment of the invention, i.e. in an X-rayimaging device where the primary radiation is X-rayradiation, the invention provides for an accurate calibration of the X-raydetector without irradiating the X-raydetector with X-rayradiation. Rather, irradiation with UV radiation as the secondary radiation provides the desired spatial secondary gain distribution image which can be used for calibration.
摘要翻译：提供了一种用于提供关于主辐射的闪烁体的空间增益分布的信息的方法，其不需要用初级辐射照射闪烁体。该方法包括用二次辐射照射闪烁体的步骤，用于产生用于所述第二辐射的闪烁体的空间二次增益分布的图像。空间二次增益分布图像对应于初级辐射的空间初级增益分布的图像。在本发明的一个实施例中，即在主辐射为X射线照射的X射线成像装置中，本发明提供了X射线检测器的精确校准，而不用X射线照射X射线检测器。相反，用UV辐射作为辅助辐射的照射提供了可用于校准的期望的空间二次增益分布图像。

6. 发明申请

US20100140484A1 REDUCING TRAP EFFECTS IN A SCINTILLATOR BY APPLICATION OF SECONDARY RADIATION 有权
标题翻译：通过应用二次辐射降低扫描仪中的陷阱效应
公开(公告)号：US20100140484A1
公开(公告)日：2010-06-10
申请号：US12594958
申请日：2008-04-08
申请人： Rudolph M. Snoeren , Heidrun Steinhauser , Nicolaas J. Noordhoek , Matthias Simon
发明人： Rudolph M. Snoeren , Heidrun Steinhauser , Nicolaas J. Noordhoek , Matthias Simon
IPC分类号： G01T1/20
CPC分类号： G01T1/2018 , G01T1/20
摘要： According to an embodiment of the invention, a radiation detector device (10) for detecting a primary radiation (6) comprises a scintillator (12) which generates a converted primary radiation in response to incoming primary radiation (6) and a photo detector (14) for detecting the converted primary radiation. The radiation detector device (10) further comprises a secondary radiation source (20) for irradiating the scintillator (12) with a secondary radiation (22) which has a wavelength different from a wavelength of the first radiation (6) and which is capable of producing a spatially more uniform response of the scintillator (12) to primary radiation. In an embodiment of the invention, the radiation detector device (10) is an X-ray detector of an X-ray imaging apparatus where the primary radiation is X-ray radiation and the secondary radiation has a wavelength between 350 nm and 450 nm. According to an embodiment, the irradiation with the secondary radiation, e.g. UV radiation, produces a uniform gain distribution of the X-ray detector (10).
摘要翻译：根据本发明的实施例，用于检测初级辐射（6）的辐射检测器装置（10）包括闪烁体（12），其响应于入射的主辐射（6）和光检测器（14）产生转换的一次辐射）用于检测转换的一次辐射。辐射检测器装置（10）还包括用于用闪光体（12）照射具有与第一辐射（6）的波长不同的波长的次辐射（22）的次辐射源（20）产生闪烁体（12）对初级辐射的空间上更均匀的响应。在本发明的一个实施例中，辐射检测器装置（10）是X射线成像装置的X射线检测器，其中初级辐射是X射线辐射，二次辐射具有在350nm与450nm之间的波长。根据一个实施例，用二次辐射的照射，例如， UV辐射，产生X射线检测器（10）的均匀增益分布。

7. 发明授权

US06844665B2 Display device and cathode ray tube 失效
标题翻译：显示装置和阴极射线管
公开(公告)号：US06844665B2
公开(公告)日：2005-01-18
申请号：US10024740
申请日：2001-12-19
申请人： Heidrun Steinhauser , Ronald Johannes Gelten
发明人： Heidrun Steinhauser , Ronald Johannes Gelten
IPC分类号： H01J29/48 , H01J29/50
CPC分类号： H01J29/503 , H01J2229/4813
摘要： A display device comprising a deflection unit and a cathode ray tube having an in-line electron gun. The electron gun comprises a main lens portion having means for generating a main lens field and an auxiliary field. Furthermore, the electron gun comprises a prefocusing lens portion having a first, a second and a third electrode for generating a prefocusing lens field. In operation, in a direction perpendicular to the in-line plane, the auxiliary field and the main lens cause the electron beam to leave the main lens substantially parallel to the in-line plane, whereby the diameter of the electron beam at a gap of the main lens at the anode side is smaller than or equal to the diameter of the aperture of the second electrode throughout the deflecton of the electron beam across the display screen. By virtue thereof, an improved picture reproduction can be obtained.
摘要翻译：一种显示装置，包括具有直列电子枪的偏转单元和阴极射线管。电子枪包括具有用于产生主透镜场和辅助场的装置的主透镜部分。此外，电子枪包括具有用于产生预聚焦透镜场的第一，第二和第三电极的预聚焦透镜部分。在操作中，在垂直于在线平面的方向上，辅助场和主透镜使得电子束离开主透镜基本上平行于直线平面，由此电子束的直径在阳极侧的主透镜小于或等于穿过显示屏的电子束的整个偏转中的第二电极的孔的直径。由此，可以获得改进的图像再现。

8. 发明授权

US5579298A Optical scanner having symmetry about an oblique divider 失效
标题翻译：光学扫描仪具有对称性的斜分隔线
公开(公告)号：US5579298A
公开(公告)日：1996-11-26
申请号：US607623
申请日：1996-02-27
申请人： Willem G. Opheij , Jozef P. H. Benschop , Heidrun Steinhauser
发明人： Willem G. Opheij , Jozef P. H. Benschop , Heidrun Steinhauser
IPC分类号： G11B7/09 , G02B26/10 , G06K7/10 , G11B7/13 , G11B7/135 , G11B7/00
CPC分类号： G11B7/131 , G11B7/1353
摘要： A device for optically scanning an information plane (2) having tracks (5). Radiation supplied by a radiation source (7) is focused on the information plane by an objective system (8). The beam reflected by the information plane is incident on a dividing element, for example, a grating (12), which divides the beam into two halves along a dividing line (17). Two sub-gratings (15, 16) at both sides of the dividing line, respectively, each form a sub-beam from one half of the beam, which sub-beams are detected by a detection system (10), which produces detection signals therefrom. A focus error signal is generated from the detector signals. According to the invention, modulation of the focus error signal by the track structure will be minimal if the dividing line (17) is located at an angle between 15.degree. and 80.degree. to the direction of the tracks.
摘要翻译：一种用于光学扫描具有轨道（5）的信息平面（2）的装置。由辐射源（7）提供的辐射由物镜系统（8）聚焦在信息平面上。由信息平面反射的光束入射在分割元件上，例如光栅（12），该光栅将光束沿分割线（17）分成两半。分割线两侧的两个子光栅（15,16）分别形成来自光束的一半的子光束，这些子光束由检测系统（10）检测，产生检测信号由此。从检测器信号产生聚焦误差信号。根据本发明，如果分隔线（17）位于与轨迹方向成15°至80°的角度，则轨道结构对聚焦误差信号的调制将是最小的。

9. 发明授权

US09427198B2 Live 3D X-ray viewing 有权
标题翻译：直播3D X线观看
公开(公告)号：US09427198B2
公开(公告)日：2016-08-30
申请号：US14343432
申请日：2012-09-13
申请人： Heidrun Steinhauser , Michael John Murdoch , Peter Prinsen
发明人： Heidrun Steinhauser , Michael John Murdoch , Peter Prinsen
IPC分类号： A61B6/02 , A61B6/00 , A61B6/03 , A61B6/12 , A61B17/00
CPC分类号： A61B6/466 , A61B6/022 , A61B6/035 , A61B6/12 , A61B6/4021 , A61B6/4028 , A61B6/4441 , A61B6/46 , A61B6/467 , A61B6/469 , A61B6/545 , A61B6/589 , A61B2017/00216 , A61B2090/368 , A61B2090/376
摘要： System for live 3D x-ray viewing comprising an x-ray source, an x-ray detector, a processing unit, a monitor and means for detecting viewer's eyes, wherein the x-ray source and the x-ray detector are arranged at a movable C-arm. The x-ray source comprises two focal spots, wherein a separation of the two focal spots is adjustable so that the image acquisition angle between the two focal spots matches the viewing angle between the two eyes.
摘要翻译：用于实时3D X射线观察的系统，包括x射线源，X射线检测器，处理单元，监视器和用于检测观察者的眼睛的装置，其中x射线源和X射线检测器被布置在可动C型臂。 x射线源包括两个焦点，其中两个焦点的分离是可调节的，使得两个焦点之间的图像获取角度与两只眼睛之间的视角匹配。

10. 发明申请

US20100232725A1 TEMPERATURE ARTIFACT CORRECTION 审中-公开
标题翻译：温度文艺校正
公开(公告)号：US20100232725A1
公开(公告)日：2010-09-16
申请号：US12294505
申请日：2007-03-15
申请人： Johannes Albert Luijendijk , Heidrun Steinhauser , Bernd Menser
发明人： Johannes Albert Luijendijk , Heidrun Steinhauser , Bernd Menser
IPC分类号： G06K9/40
CPC分类号： A61B6/00 , A61B6/585 , G01T1/2018 , G01T7/005 , G03B42/02 , H04N5/32 , H04N5/367
摘要： A system and method of generating a template of at least one artifact for use in image correction is disclosed. An image containing the artifact is generated using at least two homogeneous exposures, each generated at a different detector operating temperature. The local variance of grey values at each pixel position in the image is calculated. Each pixel in the image is then classified. A binary image is generated based on the classification. The template is then formed based on both the binary image and the image data containing the artifact.
摘要翻译：公开了一种用于生成用于图像校正的至少一个工件的模板的系统和方法。使用至少两个均匀的曝光产生包含该伪像的图像，每个曝光在不同的检测器工作温度下产生。计算图像中每个像素位置处灰度值的局部方差。然后对图像中的每个像素进行分类。基于分类生成二进制图像。然后基于二进制图像和包含伪像的图像数据形成模板。

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