专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08173177B2 Compositions of botanical extracts for cancer therapy 有权
标题翻译：用于癌症治疗的植物提取物的组合物
公开(公告)号：US08173177B2
公开(公告)日：2012-05-08
申请号：US10937707
申请日：2004-09-08
申请人： James Dao , Tom C. S. Dao , David D. Tong , Leslie Wilson , Mary Ann Jordan , William Gerwick
发明人： James Dao , Tom C. S. Dao , David D. Tong , Leslie Wilson , Mary Ann Jordan , William Gerwick
IPC分类号： A61K36/00
CPC分类号： A61K36/539 , A61K31/00 , A61K31/337 , A61K31/437 , A61K31/519 , A61K31/704 , A61K31/7068 , A61K36/074 , A61K36/185 , A61K36/537 , A61K36/82 , A61K41/00 , A61K45/06 , A61K2300/00
摘要： Methods and compositions for prevention and therapy of cancer are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of Ganoderma lucidum, an extract of Salvia miltiorrhiza and an extract of Scutellaria barbata and optionally a therapeutically effective amount of an extract of Hippophae rhamnoides are provided. Novel synergistic effects of the use of these compounds in combination therapy are disclosed. Embodiments further comprising therapeutically effective amounts of at least one chemotherapeutic agent are also provided.
摘要翻译：提供了预防和治疗癌症的方法和组合物。提供包含治疗有效量的灵芝提取物，丹参提取物和黄芩提取物和任选的治疗有效量的沙棘提取物的两种或更多种的组合物。公开了在组合疗法中使用这些化合物的新的协同效应。还提供还包含治疗有效量的至少一种化学治疗剂的实施方案。

2. 发明申请

US20110117121A1 COMPOSITIONS FOR TREATMENT AND INHIBITION OF PAIN 审中-公开
标题翻译：用于治疗和抑制疼痛的组合物
公开(公告)号：US20110117121A1
公开(公告)日：2011-05-19
申请号：US12446561
申请日：2007-10-26
申请人： James Dao , Jeff Dao , Leslie Wilson , William Gerwick , Emin Oroudjev
发明人： James Dao , Jeff Dao , Leslie Wilson , William Gerwick , Emin Oroudjev
IPC分类号： A61K36/06 , A61P25/00
CPC分类号： A61K36/537 , A61K36/074 , A61K36/539 , Y02A50/422
摘要： Methods and compositions for therapy of pain are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of Ganoderma lucidum, an extract of Salvia miltiorrhiza and an extract of Scutellaria barbata and optionally a therapeutically effective amount of an extract of Hippophae rhamnoides are provided. Novel synergistic effects of the use of these compounds in combination therapy are disclosed. Compositions exhibit multiple functions that are useful for the treatment of pain and inflammation. Compositions of the invention inhibit the activity of COX-2 to a greater extent than COX-1. Compositions of the invention also inhibit the nuclear accumulation of NF-kappaB and thus inhibit the expression of a number of proinflammatory molecules including COX-2.
摘要翻译：提供了治疗疼痛的方法和组合物。提供包含治疗有效量的灵芝提取物，丹参提取物和黄芩提取物和任选的治疗有效量的沙棘提取物的两种或更多种的组合物。公开了在组合疗法中使用这些化合物的新的协同效应。组合物表现出多种可用于治疗疼痛和炎症的功能。本发明的组合物比COX-1更大程度上抑制COX-2的活性。本发明的组合物还抑制NF-κB的核聚集，从而抑制许多促炎分子（包括COX-2）的表达。

3. 发明申请

US20050208070A1 Compositions of botanical extracts for cancer therapy 有权
标题翻译：用于癌症治疗的植物提取物的组合物
公开(公告)号：US20050208070A1
公开(公告)日：2005-09-22
申请号：US10937707
申请日：2004-09-08
申请人： James Dao , Tom Dao , David Tong , Leslie Wilson , Mary Jordan , William Gerwick
发明人： James Dao , Tom Dao , David Tong , Leslie Wilson , Mary Jordan , William Gerwick
IPC分类号： A61K20060101 , A61K31/00 , A61K36/537 , A61K36/539 , A61K36/82 , A61K41/00 , A61K45/06 , A61K35/84 , A61K35/78
CPC分类号： A61K36/539 , A61K31/00 , A61K31/337 , A61K31/437 , A61K31/519 , A61K31/704 , A61K31/7068 , A61K36/074 , A61K36/185 , A61K36/537 , A61K36/82 , A61K41/00 , A61K45/06 , A61K2300/00
摘要： Methods and compositions for prevention and therapy of cancer are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of Ganoderma lucidum, an extract of Salvia miltiorrhiza and an extract of Scutellaria barbata and optionally a therapeutically effective amount of an extract of Hippophae rhamnoides are provided. Novel synergistic effects of the use of these compounds in combination therapy are disclosed. Embodiments further comprising therapeutically effective amounts of at least one chemotherapeutic agent are also provided.
摘要翻译：提供了预防和治疗癌症的方法和组合物。提供包含治疗有效量的灵芝提取物，丹参提取物和黄芩提取物和任选的治疗有效量的沙棘提取物的两种或更多种的组合物。公开了在组合疗法中使用这些化合物的新的协同效应。还提供还包含治疗有效量的至少一种化学治疗剂的实施方案。

4. 发明授权

US06660767B2 Coumarin compounds as microtubule stabilizing agents and therapeutic uses thereof 失效
公开(公告)号：US06660767B2
公开(公告)日：2003-12-09
申请号：US10060317
申请日：2002-02-01
申请人： Robert S. Jacobs , Leslie Wilson , Hamta Madari
发明人： Robert S. Jacobs , Leslie Wilson , Hamta Madari
IPC分类号： A61K3135
CPC分类号： A61K31/00 , A61K31/352 , C07D311/10 , Y02A50/411
摘要： Compounds and compositions for stabilizing microtubules are disclosed. Also disclosed are methods of inhibiting, preventing, regulating, modulating, attenuating, stabilizing, or affecting microtubule formation or function. Methods of treating, preventing or inhibiting diseases and disorders associated with microtubule formation, function, or both by administering a microtubule stabilizing agent such as coumarin is also disclosed.

5. 发明申请

US20180008240A1 DEVICE FOR ASSAYING ANALYTES IN BODILY FLUIDS 审中-公开
公开(公告)号：US20180008240A1
公开(公告)日：2018-01-11
申请号：US15290503
申请日：2016-10-11
申请人： Matthias W. Engel , Leslie Wilson , Paul Johnson
发明人： Matthias W. Engel , Leslie Wilson , Paul Johnson
IPC分类号： A61B10/00 , G01N33/558
CPC分类号： A61B10/0045 , A61B10/0051 , A61B10/007 , A61B10/0096 , A61B2010/0006 , A61B2010/0009 , G01N33/558
摘要： A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. The sampling element can include an indicator strip for determining whether the amount of liquid sample sufficient for carrying out an assay.

6. 发明申请

US20120094303A1 DEVICE FOR ASSAYING ANALYTES IN BODILY FLUIDS 审中-公开
标题翻译：用于测定体液中分析物的装置
公开(公告)号：US20120094303A1
公开(公告)日：2012-04-19
申请号：US13211208
申请日：2011-08-16
申请人： Matthias W. ENGEL , Leslie Wilson , Paul Johnson
发明人： Matthias W. ENGEL , Leslie Wilson , Paul Johnson
IPC分类号： G01N33/53 , G01N21/75 , G01N30/00
CPC分类号： A61B10/0045 , A61B10/0051 , A61B10/007 , A61B10/0096 , A61B2010/0006 , A61B2010/0009 , G01N33/558
摘要： A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. Further, the base of the container has a central elevation via which the sample of body fluid can be conveyed from the sampler, by compression thereof on the elevation, to the at least one test strip.
摘要翻译：用于确定人体液样品中一种或多种分析物的存在和/或数量的装置具有用于接收体液样品的容器，其中内部由基部和圆周表面界定。它还包括至少一个测试条和用于接收和保持一个或多个测试条的保持元件。保持元件被设计成使得其具有对应于并适合于容器的周向圆周表面的形状。该装置还包括细长的取样元件，其具有吸收体取样器，其吸收体液样品，借助于此，体液样品被转移到容器中。此外，容器的底部具有中心高度，通过该中心高度，体液的样品可以通过压片从取样器输送到至少一个测试条。

7. 发明授权

US07599839B2 Enabling speech within a multimodal program using markup 有权
标题翻译：在使用标记的多模式程序中启用语音
公开(公告)号：US07599839B2
公开(公告)日：2009-10-06
申请号：US12029330
申请日：2008-02-11
申请人： Charles Cross , Leslie Wilson , Steven Woodward
发明人： Charles Cross , Leslie Wilson , Steven Woodward
IPC分类号： G10L11/00 , G10L13/06 , G10L21/00
CPC分类号： G10L15/22 , G06F3/167 , G10L15/26 , H04M3/4938
摘要： A method for speech enabling an application can include the step of specifying a speech input within a speech-enabled markup. The speech-enabled markup can also specify an application operation that is to be executed responsive to the detection of the speech input. After the speech input has been defined within the speech-enabled markup, the application can be instantiated. The specified speech input can then be detected and the application operation can be responsively executed in accordance with the specified speech-enabled markup.
摘要翻译：用于使应用程序语音化的方法可以包括在启用语音的标记中指定语音输入的步骤。启用语音的标记还可以指定响应于语音输入的检测执行的应用操作。在启用语音的标记中定义了语音输入后，可以实例化应用程序。然后可以检测指定的语音输入，并且可以根据指定的启用语音的标记来响应地执行应用操作。

8. 发明申请

US20070178950A1 Wearable multimodal computing device with hands-free push to talk 审中-公开
标题翻译：可穿戴式多模式计算设备，具有免提通话功能
公开(公告)号：US20070178950A1
公开(公告)日：2007-08-02
申请号：US11334838
申请日：2006-01-19
申请人： James Lewis , Leslie Wilson
发明人： James Lewis , Leslie Wilson
IPC分类号： H04M1/00
CPC分类号： H04M1/0233 , H04B1/385 , H04M1/6041 , H04M2250/12
摘要： A wearable computing system can comprise a device attachment mechanism and a push to talk actuator. The device attachment mechanism can include a device coupler and a body affixer. The device coupler can detachably couple a portable computing device to the device attachment mechanism. The body affixer can detachably affix the device attachment mechanism to a forearm of a user positioned between a wrist of the user and an elbow of the user. The push to talk actuator can be activated by the user utilizing at least one of an arm, a hand, a wrist, and a finger movement. The push to talk actuator can be coupled to an actuator attachment mechanism that is wearably attached to the user in a hands-free fashion.
摘要翻译：可穿戴计算系统可以包括设备连接机构和一键通致动器。设备连接机构可以包括设备耦合器和身体固定器。设备耦合器可以将便携式计算设备可拆卸地连接到设备连接机构。身体固定器可以将装置附接机构可拆卸地固定在位于使用者腕部和使用者的肘部之间的使用者的前臂上。一键通致动器可以由使用者利用手臂，手，手腕和手指运动中的至少一个来激活。一键通致动器可以以无手段的方式联接到可佩戴地附接到使用者的致动器附接机构。

9. 发明申请

US20050101662A1 Coumarin compounds as microtubule stabilizing agents and therapeutic uses thereof 审中-公开
标题翻译：香豆素化合物作为微管稳定剂及其治疗用途
公开(公告)号：US20050101662A1
公开(公告)日：2005-05-12
申请号：US10639577
申请日：2003-08-13
申请人： Robert Jacobs , Leslie Wilson , Hamta Madari
发明人： Robert Jacobs , Leslie Wilson , Hamta Madari
IPC分类号： A61K31/00 , A61K31/337 , A61K31/343 , A61K31/352 , A61K31/366 , A61K31/475 , A61K31/565 , A61K31/7048 , A61K45/00 , A61P9/10 , A61P19/06 , A61P25/28 , A61P29/00 , A61P31/10 , A61P35/00 , A61P43/00 , C07D311/10 , C07D311/16 , C07D311/56 , A61K31/704 , A61K31/4745
CPC分类号： A61K31/00 , A61K31/352 , C07D311/10 , Y02A50/411
摘要： Compounds and compositions for stabilizing microtubules are disclosed. Also disclosed are methods of inhibiting, preventing, regulating, modulating, attenuating, stabilizing, or affecting microtubule formation or function. Methods of treating, preventing or inhibiting diseases and disorders associated with microtubule formation, function, or both by administering a microtubule stabilizing agent such as coumarin is also disclosed.
摘要翻译：公开了用于稳定微管的化合物和组合物。还公开了抑制，预防，调节，调节，减弱，稳定或影响微管形成或功能的方法。还公开了通过施用微管稳定剂如香豆素来治疗，预防或抑制与微管形成，功能或两者相关的疾病和病症的方法。

10. 发明申请

US20080215331A1 ENABLING SPEECH WITHIN A MULTIMODAL PROGRAM USING MARKUP 有权
标题翻译：在使用标记的多模式程序中启用语音
公开(公告)号：US20080215331A1
公开(公告)日：2008-09-04
申请号：US12029330
申请日：2008-02-11
申请人： Charles Cross , Leslie Wilson , Steven Woodward
发明人： Charles Cross , Leslie Wilson , Steven Woodward
IPC分类号： G10L11/00 , G10L21/00 , G06F3/048
CPC分类号： G10L15/22 , G06F3/167 , G10L15/26 , H04M3/4938
摘要： A method for speech enabling an application can include the step of specifying a speech input within a speech-enabled markup. The speech-enabled markup can also specify an application operation that is to be executed responsive to the detection of the speech input. After the speech input has been defined within the speech-enabled markup, the application can be instantiated. The specified speech input can then be detected and the application operation can be responsively executed in accordance with the specified speech-enabled markup.
摘要翻译：用于使应用程序语音化的方法可以包括在启用语音的标记中指定语音输入的步骤。启用语音的标记还可以指定响应于语音输入的检测执行的应用操作。在启用语音的标记中定义了语音输入后，可以实例化应用程序。然后可以检测指定的语音输入，并且可以根据指定的启用语音的标记来响应地执行应用操作。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式