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1. 发明授权

US07074594B2 Guanosine triphosphate (GTP) binding protein-coupled receptor proteins 失效
标题翻译：鸟苷三磷酸（GTP）结合蛋白偶联受体蛋白
公开(公告)号：US07074594B2
公开(公告)日：2006-07-11
申请号：US10759463
申请日：2004-01-16
申请人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
发明人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
IPC分类号： C01K15/12
CPC分类号： G01N33/502 , C07K14/705 , G01N2333/72
摘要： A full-length cDNA encoding a human-derived G protein-coupled receptor protein is isolated by screening a human hippocampus library. Also, a rat-derived cDNA corresponding to the human-derived cDNA is isolated. Proteins encoded by these cDNAs have an activity of lowering intracellular cAMP concentration under stimulation with histamine. These proteins are usable as tools in screening ligands thereof or in screening candidate compounds for drugs capable of regulating signal transduction from the above proteins.
摘要翻译：通过筛选人海马文库来分离编码人衍生的G蛋白偶联受体蛋白质的全长cDNA。此外，分离与人源cDNA相对应的来自大鼠的cDNA。由这些cDNA编码的蛋白质具有降低组胺刺激下细胞内cAMP浓度的活性。这些蛋白质可用作筛选其配体或筛选能够调节来自上述蛋白质的信号转导的药物的候选化合物的工具。

2. 发明申请

US20050048522A1 Novel guanosine triphosphate (GTP) binding protein-coupled receptor proteins 失效
标题翻译：新型三磷酸鸟苷（GTP）结合蛋白偶联受体蛋白
公开(公告)号：US20050048522A1
公开(公告)日：2005-03-03
申请号：US10759463
申请日：2004-01-16
申请人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
发明人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
IPC分类号： C12N15/09 , A61K45/00 , C07D233/64 , C07K14/705 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/02 , G01N33/15 , G01N33/566 , C12Q1/68 , C07H21/04
CPC分类号： G01N33/502 , C07K14/705 , G01N2333/72
摘要： A full-length cDNA encoding a human-derived G protein-coupled receptor protein is isolated by screening a human hippocampus library. Also, a rat-derived cDNA corresponding to the human-derived cDNA is isolated. Proteins encoded by these cDNAs have an activity of lowering intracellular cAMP concentration under stimulation with histamine. These proteins are usable as tools in screening ligands thereof or in screening candidate compounds for drugs capable of regulating signal transduction from the above proteins.
摘要翻译：通过筛选人海马文库来分离编码人衍生的G蛋白偶联受体蛋白质的全长cDNA。此外，分离与人源cDNA相对应的来自大鼠的cDNA。由这些cDNA编码的蛋白质具有降低组胺刺激下细胞内cAMP浓度的活性。这些蛋白质可用作筛选其配体或筛选能够调节来自上述蛋白质的信号转导的药物的候选化合物的工具。

3. 发明申请

US20070015220A1 Novel guanosine triphosphate (GTP) binding protein-coupled receptor proteins 失效
标题翻译：新型三磷酸鸟苷（GTP）结合蛋白偶联受体蛋白
公开(公告)号：US20070015220A1
公开(公告)日：2007-01-18
申请号：US11447407
申请日：2006-06-06
申请人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
发明人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
IPC分类号： G01N33/567 , C07H21/04 , C12P21/06 , C07K14/705 , C07K16/28
CPC分类号： G01N33/502 , C07K14/705 , G01N2333/72
摘要： A full-length cDNA encoding a human-derived G protein-coupled receptor protein is isolated by screening a human hippocampus library. Also, a rat-derived cDNA corresponding to the human-derived cDNA is isolated. Proteins encoded by these cDNAs have an activity of lowering intracellular cAMP concentration under stimulation with histamine. These proteins are usable as tools in screening ligands thereof or in screening candidate compounds for drugs capable of regulating signal transduction from the above proteins.
摘要翻译：通过筛选人海马文库来分离编码人衍生的G蛋白偶联受体蛋白质的全长cDNA。此外，分离与人源cDNA相对应的来自大鼠的cDNA。由这些cDNA编码的蛋白质具有降低组胺刺激下细胞内cAMP浓度的活性。这些蛋白质可用作筛选其配体或筛选能够调节来自上述蛋白质的信号转导的药物的候选化合物的工具。

4. 发明授权

US07374895B2 Guanosine triphosphate (GTP) binding protein-coupled receptor proteins that bind histamine and are expressed in the brain 失效
标题翻译：使用在脑中表达的A G蛋白偶联的组胺受体的测定
公开(公告)号：US07374895B2
公开(公告)日：2008-05-20
申请号：US11447407
申请日：2006-06-06
申请人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
发明人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
IPC分类号： G01N33/566
CPC分类号： G01N33/502 , C07K14/705 , G01N2333/72
摘要： A full-length cDNA encoding a human-derived G protein-coupled receptor protein is isolated by screening a human hippocampus library. Also, a rat-derived cDNA corresponding to the human-derived cDNA is isolated. Proteins encoded by these cDNAs have an activity of lowering intracellular cAMP concentration under stimulation with histamine. These proteins are usable as tools in screening ligands thereof or in screening candidate compounds for drugs capable of regulating signal transduction from the above proteins.
摘要翻译：通过筛选人海马文库来分离编码人衍生的G蛋白偶联受体蛋白质的全长cDNA。此外，分离与人源cDNA相对应的来自大鼠的cDNA。由这些cDNA编码的蛋白质具有降低组胺刺激下细胞内cAMP浓度的活性。这些蛋白质可用作筛选其配体或筛选能够调节来自上述蛋白质的信号转导的药物的候选化合物的工具。

5. 发明授权

US06750322B2 Guanosine triphosphate (GTP) binding protein-coupled receptor proteins 失效
标题翻译：鸟苷三磷酸（GTP）结合蛋白偶联受体蛋白
公开(公告)号：US06750322B2
公开(公告)日：2004-06-15
申请号：US09891053
申请日：2001-06-25
申请人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
发明人： Hiraku Itadani , Tetsuo Takimura , Takao Nakamura , Masahiko Kobayashi , Ken-Ichi Tanaka , Yusuke Hidaka , Masataka Ohta
IPC分类号： C07K14705
CPC分类号： G01N33/502 , C07K14/705 , G01N2333/72
摘要： The present invention has provided a human-derived novel G protein-coupled receptor protein expressed in the brain, rat-derived protein corresponding to it, and their genes. Use of the receptors makes it possible to screen their ligands and compounds that are candidates for medicines. These ligands and candidate compounds would be useful in the diagnosis and treatment of diseases arising from disorders of signal transduction pathway mediated by the G protein-coupled receptor of the invention.
摘要翻译：通过筛选人海马文库来分离编码人衍生的G蛋白偶联受体蛋白质的全长cDNA。此外，分离与人源cDNA相对应的来自大鼠的cDNA。由这些cDNA编码的蛋白质具有降低组胺刺激下细胞内cAMP浓度的活性。这些蛋白质可用作筛选其配体或筛选能够调节来自上述蛋白质的信号转导的药物的候选化合物的工具。

6. 发明授权

US08085826B2 Nitride semiconductor laser device 有权
标题翻译：氮化物半导体激光器件
公开(公告)号：US08085826B2
公开(公告)日：2011-12-27
申请号：US12591178
申请日：2009-11-12
申请人： Yuhzoh Tsuda , Masataka Ohta , Yoshie Fujishiro
发明人： Yuhzoh Tsuda , Masataka Ohta , Yoshie Fujishiro
IPC分类号： H01S5/00
CPC分类号： H01S5/34333 , B82Y20/00 , C30B25/165 , C30B29/403 , C30B29/406 , H01S5/2004 , H01S5/3216 , H01S2301/18 , H01S2304/04
摘要： A nitride semiconductor laser device includes an n-type AlGaN clad layer, a GaN layer, a first InGaN light guide layer, a light-emitting layer, a second InGaN light guide layer, a nitride semiconductor intermediate layer, a p-type AlGaN layer, and a p-type AlGaN clad layer stacked in this order on a nitride semiconductor substrate, wherein the n-type AlGaN clad layer has an Al composition ratio of 3-5% and a thickness of 1.8-2.5 μm; the first and second InGaN light guide layers have an In composition ratio of 3-6%; the first light guide layer has a thickness of 120-160 nm and greater than that of the second light guide layer; and the p-type AlGaN layer is in contact with the p-type clad layer and has an Al composition ratio of 10-35% and greater than that of the p-type clad layer.
摘要翻译：氮化物半导体激光器件包括n型AlGaN包覆层，GaN层，第一InGaN导光层，发光层，第二InGaN导光层，氮化物半导体中间层，p型AlGaN层以及在氮化物半导体衬底上依次层叠的p型AlGaN覆盖层，其特征在于，所述n型AlGaN覆盖层的Al组成比为3-5％，厚度为1.8〜2.5μm; 第一和第二InGaN导光层的In组成比为3-6％; 第一导光层的厚度为120-160nm且大于第二导光层的厚度; p型AlGaN层与p型覆盖层接触，Al组成比为p-type覆层的10-35％以上。

7. 发明授权

US07797942B2 Gas turbine combustor having multiple independently operable burners and staging method thereof 有权
标题翻译：具有多个可独立操作的燃烧器的燃气轮机燃烧器及其分级方法
公开(公告)号：US07797942B2
公开(公告)日：2010-09-21
申请号：US11266202
申请日：2005-11-04
申请人： Toshihiko Saitoh , Masataka Ohta , Shinji Akamatsu , Masakazu Nose
发明人： Toshihiko Saitoh , Masataka Ohta , Shinji Akamatsu , Masakazu Nose
IPC分类号： F02C1/00 , F02G3/00
CPC分类号： F23R3/343 , F23R3/286
摘要： In a combustor of a gas turbine which has a pilot nozzle being installed to the center of the axis of a combustor basket and a plurality of main nozzles being installed to the vicinity of the pilot nozzle and provided with a premixing tool on the outer circumference thereof, wherein, fuel being injected as air-fuel pre-mixture from the main nozzle into the interior of a transition piece forming a combustion chamber downstream of the combustor basket is ignited by diffusion flame being generated by the pilot nozzle in the transition piece so as to generate a premixed flame in the transition piece, wherein combustion is performed by a part of the plurality of main nozzles from start-up until a predetermined load rate and then performed by adding the remaining portion of the plurality of main nozzles when the predetermined load rate is exceeded.
摘要翻译：在燃气轮机的燃烧器中，具有安装在燃烧器筐的轴心的中心的先导喷嘴，并且多个主喷嘴安装在导向喷嘴附近，并且在其外周上设置有预混合工具其特征在于，从所述主喷嘴向所述燃烧器筐下游形成燃烧室的过渡部件的内部喷射的燃料被喷射，所述扩散火焰由所述过渡部件中的先导喷嘴产生，以在过渡件中产生预混合的火焰，其中燃料由多个主喷嘴的一部分从起动直到预定的负载率进行，然后通过在预定的负载下加入多个主喷嘴的剩余部分率超过。

8. 发明授权

US06460339B2 Gas turbine fuel injector with unequal fuel distribution 有权
标题翻译：具有不均等燃料分配的燃气轮机燃油喷射器
公开(公告)号：US06460339B2
公开(公告)日：2002-10-08
申请号：US09828138
申请日：2001-04-09
申请人： Koichi Nishida , Katsunori Tanaka , Shigemi Mandai , Yutaka Kawata , Masataka Ohta
发明人： Koichi Nishida , Katsunori Tanaka , Shigemi Mandai , Yutaka Kawata , Masataka Ohta
IPC分类号： F02G300
CPC分类号： F23R3/343 , F23R3/286
摘要： A gas turbine combustor improves the fuel distribution from a main fuel nozzle, suppressing fluctuations of internal pressure and elevation of inner tube metal temperature, and enhancing the combustion stability and durability of the combustor. The gas turbine combustor is a multi-nozzle type premixing combustor with a nozzle outer tube (7) for forming and injecting a premixed gas of main fuel and combustion air divided and disposed in plural sections around a cone (4) for forming a diffusion flame by reaction between pilot fuel and combustion air disposed in a center of a section of a combustor inner tube (1). Nozzle holes (5a) of a main fuel nozzle (5) are formed in three positions at equal intervals on the nozzle main body wall, and one of them is disposed at the outer periphery of the combustor inner tube (1) on a diametral line linking between the center of the combustor inner tube (1) and the center of the main fuel nozzle (5), whereby the fuel distribution to the outer periphery is decreased.
摘要翻译：燃气轮机燃烧器改善来自主燃料喷嘴的燃料分布，抑制内部压力的波动和内管金属温度升高，提高燃烧器的燃烧稳定性和耐久性。燃气轮机燃烧器是具有喷嘴外管（7）的喷嘴外管（7）的多喷嘴型预混合燃烧器，用于形成并喷射主燃料和燃烧空气的预混合气体，燃烧空气以形成扩散火焰的锥体（4）为中心分成多个部分通过引燃燃料与设置在燃烧器内管（1）的一部分的中心的燃烧空气之间的反应。主燃料喷嘴（5）的喷嘴孔（5a）以等间隔在喷嘴主体壁上形成三个位置，其中一个位于燃烧器内管（1）的外径上，在燃烧器内管（1）的中心与主燃料喷嘴（5）的中心之间连接，从而减少了向外周的燃料分配。

9. 发明授权

US06301900B1 Gas turbine combustor with fuel and air swirler 有权
标题翻译：燃气涡轮燃烧器与燃料和空气旋流器
公开(公告)号：US06301900B1
公开(公告)日：2001-10-16
申请号：US09554447
申请日：2000-07-06
申请人： Shigemi Mandai , Masataka Ohta , Hideki Haruta , Koichi Nishida , Shinji Akamatsu , Masahiro Kamogawa
发明人： Shigemi Mandai , Masataka Ohta , Hideki Haruta , Koichi Nishida , Shinji Akamatsu , Masahiro Kamogawa
IPC分类号： F23R314
CPC分类号： F23D11/38 , F23D11/107 , F23D2900/00016 , F23R3/28
摘要： A nozzle cap (10) is disposed downstream of a nozzle body (1) of a combustor for a gas turbine, an inner surface part (12) of which is of a conical shape diverging downstream to define a fuel-jet guide (17) for guiding fuel jet ejected from one or more nozzle holes (3) provided at the center of a downstream end surface of the nozzle body. Fuel ejected from the one or more nozzle holes smoothly runs along the fuel-jet guide without remaining there to join with a swirl stream (S) in a swirl path (9), and to burn without generating smoke. Air introduced into a first auxiliary air path (6) defined between the nozzle body and a partition (5) at a position upstream thereof passes through a second auxiliary air path (16) defined between a downstream end surface (2) of the nozzle body (1) and an upstream end surface (13) of the nozzle cap and reaches an entrance (19) of the fuel-jet guide. The air then flows along the fuel-jet guide to cool the nozzle cap and prevent the fuel ejected from the one or more nozzle holes from sticking to the nozzle cap.
摘要翻译：喷嘴盖（10）设置在用于燃气轮机的燃烧器的喷嘴主体（1）的下游，其内表面部分（12）具有向下游扩散的锥形形状，以限定燃料喷射引导件（17）用于引导从设置在喷嘴体的下游端面的中心的一个或多个喷嘴孔（3）喷出的燃料喷射。从一个或多个喷嘴孔喷出的燃料沿燃料喷射导向装置平滑地延伸，而不残留在漩涡路径（9）中的旋流（S），并且燃烧而不产生烟雾。被引入第一辅助空气通道（6）中的空气通道（6），其限定在喷嘴主体和分隔件（5）之间的位于其上游的位置处，通过限定在喷嘴体的下游端面（2）之间的第二辅助空气通道（1）和喷嘴盖的上游端表面（13）到达燃料喷射引导件的入口（19）。然后空气沿着燃料喷射引导件流动以冷却喷嘴帽，并且防止从一个或多个喷嘴孔喷出的燃料粘附到喷嘴帽。

10. 发明授权

US4446789A Dot matrix printer 失效
标题翻译：点阵打印机
公开(公告)号：US4446789A
公开(公告)日：1984-05-08
申请号：US326319
申请日：1981-12-01
申请人： Michio Matsumoto , Masao Kitamura , Masataka Ohta , Takeshi Ohshima
发明人： Michio Matsumoto , Masao Kitamura , Masataka Ohta , Takeshi Ohshima
IPC分类号： B41J2/245 , B41J19/04 , B41J25/00 , B41J3/12
CPC分类号： B41J25/006
摘要： A dot matrix printer having a printer hammer bank carried on a frame to allow movement parallel to the platen. A balancing member is suspended from the head hammer bank by resilient springs and carries a motor for driving the head hammer bank in a reciprocating manner. A linkage further couples the head hammer bank and the balancing member so that the balancing member moves in a direction opposite to that of the head hammer bank.
摘要翻译：具有承载在框架上以允许平行于压盘的移动的打印机锤组的点阵打印机。平衡构件通过弹性弹簧从头锤组悬挂，并且以往复方式携带用于驱动头锤组的电动机。联动装置进一步联接头锤组和平衡构件，使得平衡构件沿与头锤组相反的方向移动。

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