专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US4229580A Preparation of 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-ones 失效
标题翻译： 1-噻唑基-3,3-二甲基-1-苯氧基 - 丁-2-酮的制备
公开(公告)号：US4229580A
公开(公告)日：1980-10-21
申请号：US885053
申请日：1978-03-09
申请人： Hermann Arold , Hans-Ludwig Elbe , Eckart Kranz , Wolfgang Kramer , Jorg Stetter , Claus Stolzer , Rudolf Thomas
发明人： Hermann Arold , Hans-Ludwig Elbe , Eckart Kranz , Wolfgang Kramer , Jorg Stetter , Claus Stolzer , Rudolf Thomas
IPC分类号： A01N43/50 , A01N43/836 , C07D233/60 , C07D249/08 , C07D521/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： In the reaction of 1-chloro-3,3-dimethylbutan-2-one with a phenol to form an ether-ketone, halogenating it to form a halogenoether-ketone and reacting it with imidazole or 1,2,4-triazole to form a 1-azolyl-3,3-dimethyl-1-phenoxybutan-2-one of the formula ##STR1## in which X is N or CH,n is an integer from 0 to 4, andY each independently is halogen, phenyl, phenoxy, nitro, alkyl, alkoxy or cycloalkyl,the improvement which comprises effecting all steps successively in an aromatic hydrocarbon or chlorinated aliphatic or aromatic hydrocarbon as solvent without intermediate isolation. The products are obtained in high yield.
摘要翻译：在1-氯-3,3-二甲基丁-2-酮与苯酚反应形成醚 - 酮的反应中，将其卤化形成卤代醚 - 酮并与咪唑或1,2,4-三唑反应形成其中X为N或CH，n为0至4的整数，并且Y各自独立地为卤素，苯基，环烷基，环烷基，苯氧基，硝基，烷基，烷氧基或环烷基，其改进包括在芳族烃或氯化脂族或芳族烃作为溶剂中连续进行所有步骤而不中间分离。以高产率获得产品。

2. 发明授权

US4388465A Preparation of phenoxy-azolyl-butanone derivatives 失效
标题翻译：苯氧基 - 唑基 - 丁酮衍生物的制备
公开(公告)号：US4388465A
公开(公告)日：1983-06-14
申请号：US300071
申请日：1981-09-08
申请人： Hans-Ludwig Elbe , Hermann Arold , Eckart Kranz , Claus Stolzer
发明人： Hans-Ludwig Elbe , Hermann Arold , Eckart Kranz , Claus Stolzer
IPC分类号： A01N43/50 , A01N43/653 , C07D233/60 , C07D249/08 , C07D521/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： In the preparation of a phenoxy-azolyl-butanone derivative of the formula ##STR1## in which X is a halogen atom,Y is a hydrogen or halogen atom, andAz is an imidazolyl radical or a 1,2,4-triazolyl radical,wherein dichloropinacolin of the formulaCl.sub.2 CH--CO--C(CH.sub.3).sub.3is reacted with an azole of the formulaAz--Hand a phenol of the formula ##STR2## in the presence of an acid-binding agent, the improvement which comprises carrying out the reaction in the presence of a water-immiscible organic solvent at a temperature between about 40.degree. and 150.degree. C., adding to the solvent at a temperature between about 0.degree. and +80.degree. C. a mineral acid, thereby to precipitate the mineral acid salt of the phenoxy-azolyl-butanone derivative, and separating such salt. Surprisingly the product does not hydrolyze when standing in contact with the mineral acid solution. The product is a known fungicide.
摘要翻译：在制备其中X是卤素原子的式“IMAGE”的苯氧基 - 唑基 - 丁酮衍生物的制备中，Y是氢或卤素原子，并且Az是咪唑基或1,2,4-三唑基，其中式Cl2CH-CO-C（CH3）3的二氯青霉素与酸结合剂存在下与式为Az-H的唑和式“IMAGE”的苯酚反应，其改进包括进行在与水不混溶的有机溶剂的存在下在约40℃至150℃的温度下反应，在约0℃至+ 80℃的温度下加入无机酸，从而沉淀出苯氧基 - 唑基 - 丁酮衍生物的无机酸盐，并分离此盐。令人惊讶的是，当与无机酸溶液接触时，产物不会水解。该产品是已知的杀真菌剂。

3. 发明授权

US5081265A Microbicidal substituted dioxolanes 失效
标题翻译：微生物取代的二氧化物
公开(公告)号：US5081265A
公开(公告)日：1992-01-14
申请号：US582581
申请日：1990-09-14
申请人： Hans-Ludwig Elbe , Eckart Kranz , Wilhelm Brandes , Stefan Dutzmann , Gerd Hanssler
发明人： Hans-Ludwig Elbe , Eckart Kranz , Wilhelm Brandes , Stefan Dutzmann , Gerd Hanssler
IPC分类号： C07D317/26 , A01N43/50 , A01N43/653 , C07C45/00 , C07C45/75 , C07C49/245 , C07C49/255 , C07C49/84 , C07C67/00 , C07C323/22 , C07C323/65 , C07D405/00 , C07D407/04 , C07D409/14 , C07D521/00
CPC分类号： C07D231/12 , A01N43/653 , C07D233/56 , C07D249/08
摘要： Fungicidal dioxolanes of the formula ##STR1## in which R.sup.1 represents optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkinyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted aryl, optionally substituted aryloxy, optionally substituted arylthio, optionally substituted arylsulphinyl, optionally substituted arylsulphonyl, optionally substituted arylalkyl, optionally substituted aryloxyalkyl, optionally substituted arylthioalkyl, optionally substituted arylsulphinylalkyl, optionally substituted arylsulphonylalkyl, optionally substituted aralkyloxyalkyl, optionally substituted aralkylthioalkyl, optionally substituted aralkylsulphinylalkyl or optionally substituted aralkylsulphonylalkyl,R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 independently of one another represent hydrogen, alkyl or cycloalkyl, orR.sup.3 and R.sup.4 together represent divalent alkanediyl and/orR.sup.5 and R.sup.6 together represent divalent alkanediyl andA represents nitrogen or a CH group,and addition products thereof with acids and metal salts. Also novel intermediates of the formulas ##STR2##

4. 发明授权

US4988715A Microbicidal substituted dioxolanes 失效
标题翻译：杀菌剂取代二氧戊环
公开(公告)号：US4988715A
公开(公告)日：1991-01-29
申请号：US389032
申请日：1989-08-03
申请人： Hans-Ludwig Elbe , Eckart Kranz , Wilhelm Brandes , Stefan Dutzmann , Gerd Hanssler
发明人： Hans-Ludwig Elbe , Eckart Kranz , Wilhelm Brandes , Stefan Dutzmann , Gerd Hanssler
IPC分类号： C07D317/26 , A01N43/50 , A01N43/653 , C07C45/00 , C07C45/75 , C07C49/245 , C07C49/255 , C07C49/84 , C07C67/00 , C07C323/22 , C07C323/65 , C07D405/00 , C07D407/04 , C07D409/14 , C07D521/00
CPC分类号： C07D231/12 , A01N43/653 , C07D233/56 , C07D249/08
摘要： Fungicidal dioxolanes of the formula ##STR1## in which R.sup.1 represents optionally substituted alkyl, or other radicalsR.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 independently of one another represent hydrogen, alkyl or cycloalkyl, orR.sup.3 and R.sup.4 together represent divalent alkanediyl and/orR.sup.5 and R.sup.6 together represent divalent alkanediyl andA represents nitrogen or a CH group,and addition products thereof with acids and metal salts. Also novel intermediates of the formulas ##STR2##
摘要翻译：其中R 1表示任选取代的烷基或其它基团R 2，R 3，R 4，R 5和R 6彼此独立地表示的式（I）的杀真菌二氧戊环代表氢，烷基或环烷基，或者R 3和R 4一起代表二价烷二基和/或R 5和R 6一起表示二价烷二基，A表示氮或CH基，并且其与酸和金属盐的加成产物。（VIa）（VIIa）（VIIa）（VIIa）（VIIa）（VIIa）中的新颖的中间体

5. 发明授权

US4806559A Novel substituted hydroxyalkyl-azole antimycotic agents 失效
标题翻译：新型取代的羟烷基 - 唑类抗真菌剂
公开(公告)号：US4806559A
公开(公告)日：1989-02-21
申请号：US757033
申请日：1985-07-18
申请人： Hans-Ludwig Elbe , Jorg Stetter , Karl H. Buchel , Klaus Schaller , Manfred Plempel
发明人： Hans-Ludwig Elbe , Jorg Stetter , Karl H. Buchel , Klaus Schaller , Manfred Plempel
IPC分类号： A61K31/41 , A61K31/415 , A61P31/04 , C07D233/60 , C07D233/64 , C07D249/08 , C07D303/22 , C07D521/00 , A01N43/64
CPC分类号： C07D303/22 , C07D231/12 , C07D233/56 , C07D249/08
摘要： An antimycotic agent, comprising a compound of the formula ##STR1## in which R.sup.1 is hydrogen, alkyl, optionally substituted phenyl or optionally substituted benzyl,R.sup.2 is hydrogen, alkyl, alkenyl, alkynyl, optionally substituted phenyl or optionally substituted benzyl,R.sup.3 and Y each independently is halogen, alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenoxyalkyl,R.sup.4 and R.sup.5 each independently is alkyl,X is a nitrogen atom or the CH group,m is 0, 1, 2 or 3,n is 1 or 2, andp is 0, 1 or 2,or an acid addition salt thereof.
摘要翻译：一种抗真菌剂，其包含其中R 1为氢，烷基，任选取代的苯基或任选取代的苄基的式“IMAGE”化合物，R 2为氢，烷基，烯基，炔基，任选取代的苯基或任选取代的苄基，R 3和Y 各自独立地是卤素，烷基，环烷基，烷氧基，烷硫基，卤代烷基，卤代烷氧基，卤代烷硫基，任选取代的苯基，任选取代的苯氧基，任选取代的苯基烷基或任选取代的苯氧基烷基，R 4和R 5各自独立地是烷基，X是氮原子或 CH基，m为0,1,2或3，n为1或2，p为0,1或2，或其酸加成盐。

6. 发明授权

US4316910A Combating arthropods with substituted 2-carbamoyloximino-butanes 失效
标题翻译：与节肢动物与取代的2-氨基甲酰氨基丁烷反接
公开(公告)号：US4316910A
公开(公告)日：1982-02-23
申请号：US176814
申请日：1980-08-11
申请人： Jorg Stetter , Bernhard Homeyer , Ingeborg Hammann , Hans-Ludwig Elbe
发明人： Jorg Stetter , Bernhard Homeyer , Ingeborg Hammann , Hans-Ludwig Elbe
IPC分类号： A01N47/24 , C07C45/63 , C07C45/67 , C07C49/16 , C07C67/00 , C07C313/00 , C07C317/28 , C07C323/47 , C07C381/08 , A01N47/12 , C07C149/437
CPC分类号： C07C323/47 , A01N47/24 , C07C317/28 , C07C45/63 , C07C45/673 , C07C49/16
摘要： Substituted 2-carbamoyloximino-butanes of the formula ##STR1## in which R is alkyl or alkylthioalkyl,R.sup.1 is alkyl, alkoxyalkyl, alkenyl or alkynyl,R.sup.2 is hydrogen, alkyl or --SR.sup.3,R.sup.3 is alkyl, halogenoalkyl, optionally substituted phenyl, alkoxycarbonyl, --N(CH.sub.3)R.sup.4, or a radical identical to that to which --SR.sup.3 is bonded,R.sup.4 is alkyl, alkoxycarbonyl or optionally substituted phenylsulphonyl,X is hydrogen or halogen,Y is hydrogen or halogen,Z is halogen, andn is 0, 1 or 2,which possess arthropodicidal activity.
摘要翻译：其中R为烷基或烷硫基烷基，R 1为烷基，烷氧基烷基，烯基或炔基，R 2为氢，烷基或-SR 3，R 3为烷基，卤代烷基，任选取代的苯基，烷氧基羰基，-N（CH 3）R 4，或与-SR 3键合的基团相同的基团，R4是烷基，烷氧基羰基或任选取代的苯基磺酰基，X是氢或卤素，Y是氢或卤素，Z是卤素，n是 0，1或2，具有节肢动物活性。

7. 发明授权

US4747869A Substituted azolyl-ketones and -alcohols 失效
标题翻译：取代的唑基酮和醇
公开(公告)号：US4747869A
公开(公告)日：1988-05-31
申请号：US724375
申请日：1985-04-18
申请人： Wolfgang Kramer , Karl H. Buchel , Klaus Ditgens , Hans-Ludwig Elbe , Gerhard Jager , Manfred Jautelat , Klaus Lurssen , Paul Reinecke
发明人： Wolfgang Kramer , Karl H. Buchel , Klaus Ditgens , Hans-Ludwig Elbe , Gerhard Jager , Manfred Jautelat , Klaus Lurssen , Paul Reinecke
IPC分类号： A01N43/50 , A01N43/653 , C07C17/269 , C07C43/225 , C07C45/51 , C07C45/59 , C07C49/16 , C07C49/185 , C07D233/60 , C07D249/08 , C07D317/26 , C07D521/00 , A61K31/41
CPC分类号： C07D231/12 , A01N43/50 , A01N43/653 , C07C17/269 , C07C43/225 , C07C45/513 , C07C45/59 , C07C49/16 , C07C49/185 , C07D233/56 , C07D249/08 , C07D317/26
摘要： Substituted azoyl-ketones and -alcohols of the formula ##STR1## in which A is a nitrogen atom or the CH group,B is CO or CH(OH),R.sup.1 is alkyl, alkenyl, alkinyl, optionally substituted phenylalkyl, optionally substituted cycloalkyl or optionally substituted cycloalkylalkyl,R.sup.2 is optionally substituted cycloalkyl or the grouping --C(CH.sub.3).sub.2 R.sup.3, andR.sup.3 is alkyl having more than 2 carbon atoms, alkenyl, alkinyl or the --CH.dbd.O group or a derivative thereof,or addition products thereof with acids or metal salts, exhibit plant growth regulating and fungicidal properties, several intermediates therefor are new.
摘要翻译：取代的式（IMAGE）的芳基酮和醇，其中A是氮原子或CH基团，B是CO或CH（OH），R 1是烷基，烯基，炔基，任选取代的苯基烷基，任选取代的环烷基或任选取代的环烷基烷基，R 2是任选取代的环烷基或基团-C（CH 3）2 R 3，并且R 3是具有多于2个碳原子的烷基，烯基，炔基或-CH = O基团或其衍生物，或其加成产物与酸或金属盐，表现出植物生长调节和杀真菌性能，其中几个是新的。

8. 发明授权

US4472395A Combating fungi with novel 2-azolylmethyl-1,3-dioxolane and -dioxane derivatives 失效
标题翻译：用新型2-吡唑基甲基-1,3-二氧戊环和二恶烷衍生物灭菌
公开(公告)号：US4472395A
公开(公告)日：1984-09-18
申请号：US343054
申请日：1982-01-27
申请人： Wolfgang Kramer , Karl H. Buchel , Hans-Ludwig Elbe , Udo Kraatz , Wolf Reiser , Andreas Schulze , Erik Regel , Wilhelm Brandes , Paul-Ernest Frohberger
发明人： Wolfgang Kramer , Karl H. Buchel , Hans-Ludwig Elbe , Udo Kraatz , Wolf Reiser , Andreas Schulze , Erik Regel , Wilhelm Brandes , Paul-Ernest Frohberger
IPC分类号： C07D405/06 , A61K31/41 , A61P31/04 , C07D521/00 , A01N43/50 , A01N43/64 , C07D405/14
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： A 2-azolylmethyl-1,3-dioxolane or -dioxane derivative of the formula ##STR1## in which Az is imidazol-1-yl or 1,2,4-triazol-1-yl,R.sup.1, R.sup.2, R.sup.3 and R.sup.5 each independently is hydrogen or alkyl, orR.sup.1 and R.sup.3 together are an optionally substituted multi-membered methylene bridge,R.sup.4 is hydrogen, optionally substituted alkyl, optionally substituted aryl or optionally substituted aralykyl,m is 0 or 1,R.sup.6 is hydrogen, halogen, cyano, alkyl, optionally substituted aryl, --X--R.sup.7, --COOR.sup.8 or --CONHR.sup.9,X is oxygen, sulphur, SO, or SO.sub.2,R.sup.7 is alkyl, halogenoalkyl, cyano, optionally substituted aralkyl or optionally substituted aryl,R.sup.8 is alkyl,R.sup.9 is alkyl or optionally substituted aryl, andn is 0 or 1, or a plant-tolerated acid addition salt or metal salt complex thereof which possesses fungicidal activity.
摘要翻译：其中Az为咪唑-1-基或1,2,4-三唑-1-基的式（Ⅰ）的2-吡唑基甲基-1,3-二氧戊环或二恶烷衍生物，R1，R2，R3 R 5和R 5各自独立地为氢或烷基，或者R 1和R 3一起为任选取代的多元亚甲基桥，R 4为氢，任选取代的烷基，任选取代的芳基或任选取代的芳烷基，m为0或1，R 6为氢，卤素，氰基，烷基，任选取代的芳基，-X-R7，-COOR8或-CONHR9，X是氧，硫，SO或SO2，R7是烷基，卤代烷基，氰基，任选取代的芳烷基或任选取代的芳基，烷基，R9为烷基或任选取代的芳基，n为0或1，或其具有杀真菌活性的植物耐受酸加成盐或金属盐络合物。

9. 发明授权

US4406909A Combating fungi with 4-substituted 1-azolyl-1-phenoxy-3,3-dimethyl-butan-2-ones and -ols 失效
标题翻译：用4-取代的1-噻唑基-1-苯氧基-3,3-二甲基 - 丁-2-酮和醇灭菌
公开(公告)号：US4406909A
公开(公告)日：1983-09-27
申请号：US265050
申请日：1981-05-19
申请人： Wolfgang Kramer , Hans-Ludwig Elbe , Karl H. Buchel , Wilhelm Brandes , Paul-Ernst Frohberger
发明人： Wolfgang Kramer , Hans-Ludwig Elbe , Karl H. Buchel , Wilhelm Brandes , Paul-Ernst Frohberger
IPC分类号： A01N43/48 , A01N43/50 , A01N43/64 , A01N43/653 , C07C45/63 , C07C45/71 , C07C49/16 , C07C49/255 , C07D233/60 , C07D249/08 , C07D521/00
CPC分类号： C07D231/12 , A01N43/50 , A01N43/653 , C07C323/00 , C07C45/63 , C07C45/71 , C07C49/16 , C07C49/255 , C07D233/56 , C07D249/08
摘要： A fungicidally active 4-substituted-1-azolyl-1-phenoxy-3,3-dimethyl-butan-2-one or -ol of the formula ##STR1## in which A is a nitrogen atom or CH,B is --CO-- or CH(OH),R is cyano or X--R.sup.1,R.sup.1 is alkyl, optionally substituted aryl or optionally substituted aralkyl,X is oxygen, sulphur, SO or SO.sub.2,Z each independently is halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, alkylsulphonyl, nitro, cyano, alkoxycarbonyl or optionally substituted phenyl, andn is 0, 1, 2 or 3,or an addition product thereof with a physiologically acceptable acid or with a metal salt. Intermediates therefor of the formula ##STR2## are also new.
摘要翻译： A为氮原子或CH的杀真菌活性的4-取代-1-吡唑基-1-苯氧基-3,3-二甲基 - 丁-2-酮或其结构式为“IMAGE”的醇，B为-CO- 或CH（OH），R是氰基或X-R 1，R 1是烷基，任选取代的芳基或任选取代的芳烷基，X是氧，硫，SO或SO 2，Z各自独立地是卤素，烷基，卤代烷基，烷氧基，烷硫基，烷基磺酰基，硝基，氰基，烷氧基羰基或任选取代的苯基，n为0,1,2或3，或其与生理上可接受的酸或金属盐的加成产物。具有公式“IMAGE”和“IMAGE”的中间体也是新的。

10. 发明授权

US4451281A Fungicidal and plant growth-regulating 1-azolyl-2-oximinobutane and use 失效
标题翻译：杀菌和植物生长调节1-吖唑-2-基亚氨基丁烷并使用
公开(公告)号：US4451281A
公开(公告)日：1984-05-29
申请号：US490688
申请日：1983-05-02
申请人： Hans-Ludwig Elbe , Wolfgang Kramer , Karl H. Buchel , Klaus Lurssen , Paul Reinecke , Hans Scheinpflug
发明人： Hans-Ludwig Elbe , Wolfgang Kramer , Karl H. Buchel , Klaus Lurssen , Paul Reinecke , Hans Scheinpflug
IPC分类号： A01N43/50 , A01N43/64 , A01N43/647 , A01N43/653 , A61K31/41 , A61P31/04 , C07C45/63 , C07C49/16 , C07D233/60 , C07D233/61 , C07D249/08 , C07D521/00
CPC分类号： C07D231/12 , A01N43/50 , A01N43/653 , C07C323/00 , C07C45/63 , C07C49/16 , C07D233/56 , C07D249/08
摘要： 1-Azolyl-2-oximinobutane derivatives of the formula ##STR1## in which A is nitrogen or CH,R.sup.1 is hydrogen, alkyl, halogenoalkyl, alkenyl, alkinyl, or optionally substituted benzyl, phenyl, cycloalkyl, cycloalkylalkyl or cycloalkenyl, andR.sup.2 is optionally substituted phenyl, phenoxy, phenylthio, phenylsulphinyl or phenylsulphonyl,or physiologically acceptable addition products thereof with acids or metal salts, which possess fungicidal and plant growth-regulating activities.
摘要翻译：其中A为氮或CH，R 1为氢，烷基，卤代烷基，烯基，炔基或任选取代的苄基，苯基，环烷基，环烷基烷基或环烯基，而R2为1-芳基-2-肟基丁烷衍生物任选取代的苯基，苯氧基，苯硫基，苯基亚磺酰基或苯基磺酰基，或其与酸或金属盐的生理上可接受的加成产物，其具有杀真菌剂和植物生长调节活性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式