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1. 发明申请

US20070112387A1 Method and system for detecting capture using a coronary vein electrode 有权
公开(公告)号：US20070112387A1
公开(公告)日：2007-05-17
申请号：US11600569
申请日：2006-11-16
申请人： Scott Meyer , Haris Sih , Paul Haefner
发明人： Scott Meyer , Haris Sih , Paul Haefner
IPC分类号： A61N1/362
CPC分类号： A61N1/3712 , A61N1/3714
摘要： A method and device provide for determining capture in multiple chambers of a patient's heart using an electrode inserted into a coronary vein of the patient's heart. The coronary vein electrode is positioned adjacent to multiple heart chambers and is responsive to cardiac signals originating in the multiple chambers. The coronary vein electrode may be coupled to a single sense amplifier to detect the cardiac signals. Pace pulses may be applied to multiple heart chambers simultaneously or according to a phased timing sequence. Cardiac signals responsive to the pace pulses sensed using the coronary vein electrode may be used to verify capture in the multiple chambers of the heart.

2. 发明申请

US20060095082A1 Cardiac therapy triggered by capture verification 有权
公开(公告)号：US20060095082A1
公开(公告)日：2006-05-04
申请号：US11300674
申请日：2005-12-14
申请人： Haris Sih , Scott Meyer , Paul Haefner
发明人： Haris Sih , Scott Meyer , Paul Haefner
IPC分类号： A61N1/39
CPC分类号： A61N1/3962
摘要： The present invention provides methods and systems for tachyarrhythmia therapy involving pacing the heart to prior to the application of a cardioversion/defibrillation shock. One or more pace pulses are delivered to the arrhythmic chamber or chambers. The pace pulses may be delivered to the heart at an adaptable rate selected to organize the electrical activity of the heart. If the pace pulses produce capture, cardioversion/defibrillation stimulation is delivered.

3. 发明申请

US20050131478A1 Cardiac response classification using multisite sensing and pacing 有权
标题翻译：心脏反应分类采用多站点检测和起搏
公开(公告)号：US20050131478A1
公开(公告)日：2005-06-16
申请号：US10735519
申请日：2003-12-12
申请人： Jaeho Kim , Joseph Bocek , Scott Meyer , Paul Haefner , Haris Sih
发明人： Jaeho Kim , Joseph Bocek , Scott Meyer , Paul Haefner , Haris Sih
IPC分类号： A61B5/0452 , A61N1/362 , A61N1/37
CPC分类号： A61N1/371 , A61B5/04525 , A61B5/7217 , A61B5/7264 , A61N1/368
摘要： Methods and devices for classifying a cardiac pacing response involve using a first electrode combination for pacing and a second electrode combination for sensing a cardiac signal following pacing. The cardiac response to pacing may be classified using the sensed cardiac signal. One process involves using the sensed cardiac signal to detect the cardiac response as a fusion/pseudofusion beat. Another process involves using the sensed cardiac signal to classify the cardiac response to pacing as one of at least three cardiac response types.
摘要翻译：用于分类心脏起搏反应的方法和装置涉及使用用于起搏的第一电极组合和用于感测起搏后的心脏信号的第二电极组合。可以使用感测到的心脏信号来分类对起搏的心脏反应。一个过程涉及使用感测到的心脏信号来检测作为融合/假融合搏动的心脏反应。另一个过程涉及使用所感测到的心脏信号将心脏起搏应答分为至少三种心脏反应类型之一。

4. 发明申请

US20050131476A1 Cardiac response classification using multiple classification windows 有权
标题翻译：使用多个分类窗口的心脏反应分类
公开(公告)号：US20050131476A1
公开(公告)日：2005-06-16
申请号：US10733869
申请日：2003-12-11
申请人： Jaeho Kim , Joseph Bocek , Scott Meyer , Paul Haefner , Haris Sih
发明人： Jaeho Kim , Joseph Bocek , Scott Meyer , Paul Haefner , Haris Sih
IPC分类号： A61B5/0452 , A61N1/362 , A61B5/0402 , A61N1/37
CPC分类号： A61B5/7264 , A61B5/04525 , A61B5/7217 , A61N1/371
摘要： Methods and devices for classifying a cardiac response to pacing involve establishing a plurality of classification windows relative to and following a pacing pulse. One or more characteristics of a cardiac signal sensed following the pacing pulse are detected within one or more particular classification windows. The characteristics may be compared to one or more references. Classification of the cardiac response may be performed based on the comparison of the one or more characteristics to the one or more references and the particular classification windows in which the one or more characteristics are detected.
摘要翻译：用于将心脏反应分类到起搏的方法和装置涉及建立相对于起搏脉冲和起搏脉冲之后的多个分类窗口。在一个或多个特定分类窗口中检测到在起搏脉冲之后感测的心脏信号的一个或多个特征。特征可以与一个或多个参考进行比较。心脏反应的分类可以基于一个或多个特征与一个或多个参考和检测到一个或多个特征的特定分类窗口的比较来执行。

5. 发明授权

US09655540B2 Subcutaneous cardiac signal discrimination employing non-electrophysiologic signal 有权
公开(公告)号：US09655540B2
公开(公告)日：2017-05-23
申请号：US12983565
申请日：2011-01-03
申请人： Paul Haefner
发明人： Paul Haefner
IPC分类号： A61B5/02 , A61B5/0464 , A61B5/0428 , A61B5/00 , A61N1/365 , A61N1/39
CPC分类号： A61B5/0464 , A61B5/0428 , A61B5/7203 , A61N1/36585 , A61N1/3956
摘要： A cardiac monitoring and/or stimulation system includes a housing coupled to a plurality of electrodes configured for subcutaneous non-intrathoracic sensing. A signal processor receives a plurality of composite signals associated with a plurality of sources, separates a signal from the plurality of composite signals, and identifies the separated signal as a cardiac signal using information derived from a non-electrophysiologic sensor, such as an accelerometer or acoustic transducer. The signal processor may iteratively correlate separated signals from the plurality of composite signals with a non-electrophysiologic sensor signal until the cardiac signal is identified.

6. 发明授权

US07996071B2 Biopotential signal source separation using source impedances 失效
标题翻译：使用源阻抗的生物电位信号源分离
公开(公告)号：US07996071B2
公开(公告)日：2011-08-09
申请号：US12494768
申请日：2009-06-30
申请人： Apurv Kamath , Darrel Orvin Wagner , Paul Haefner , Marina Brockway
发明人： Apurv Kamath , Darrel Orvin Wagner , Paul Haefner , Marina Brockway
IPC分类号： A61B5/04
CPC分类号： A61B5/0464 , A61B5/042 , A61B5/0428 , A61N1/36585 , A61N1/3956
摘要： Cardiac methods and devices that separate signals using at least two composite signals acquired at least at two input impedances. A target source impedance may be selected, and a cardiac signal may be separated from composite signals using the selected target source impedance. Medical systems include a cardiac device having a housing that provides amplification circuitry configured to have a first amplifier input impedance and a second amplifier input impedance, such as using two separate circuits or switching between two input impedances. One or more electrode assemblies are coupled to the amplification circuitry. A signal processor is provided in the housing configured to separate a source signal using a first composite signal detected at the first input impedance and a second composite signal detected at the second input impedance. The phase response of the first input amplifier circuit is about equal to that of the second input amplifier circuit.
摘要翻译：使用至少两个输入阻抗获取的至少两个复合信号分离信号的心脏方法和装置。可以选择目标源阻抗，并且可以使用所选择的目标源阻抗将心脏信号与复合信号分离。医疗系统包括具有壳体的心脏装置，其提供被配置为具有第一放大器输入阻抗和第二放大器输入阻抗的放大电路，例如使用两个分离的电路或在两个输入阻抗之间切换。一个或多个电极组件耦合到放大电路。信号处理器设置在壳体中，配置成使用在第一输入阻抗处检测到的第一复合信号和在第二输入阻抗处检测到的第二复合信号来分离源信号。第一输入放大器电路的相位响应大约等于第二输入放大器电路的相位响应。

7. 发明授权

US07865233B2 Subcutaneous cardiac signal discrimination employing non-electrophysiologic signal 有权
标题翻译：使用非电生理信号的皮下心脏信号鉴别
公开(公告)号：US07865233B2
公开(公告)日：2011-01-04
申请号：US10784478
申请日：2004-02-23
申请人： Paul Haefner
发明人： Paul Haefner
IPC分类号： A61B5/0452
CPC分类号： A61B5/0464 , A61B5/0428 , A61B5/7203 , A61N1/36585 , A61N1/3956
摘要： A cardiac monitoring and/or stimulation system includes a housing coupled to a plurality of electrodes configured for subcutaneous non-intrathoracic sensing. A signal processor receives a plurality of composite signals associated with a plurality of sources, separates a signal from the plurality of composite signals, and identifies the separated signal as a cardiac signal using information derived from a non-electrophysiologic sensor, such as an accelerometer or acoustic transducer. The signal processor may iteratively correlate separated signals from the plurality of composite signals with a non-electrophysiologic sensor signal until the cardiac signal is identified.
摘要翻译：心脏监测和/或刺激系统包括耦合到配置用于皮下非胸内感测的多个电极的壳体。信号处理器接收与多个源相关联的多个复合信号，从多个复合信号中分离信号，并使用从非电生理传感器（例如加速度计或者加速度计）得到的信息将分离的信号识别为心脏信号声换能器。信号处理器可以将来自多个复合信号的分离的信号与非电生理传感器信号迭代地相关，直到识别出心脏信号。

8. 发明申请

US20090118626A1 Calculating Respiration Parameters Using Impedance Plethysmography 审中-公开
标题翻译：使用阻抗体积描记法计算呼吸参数
公开(公告)号：US20090118626A1
公开(公告)日：2009-05-07
申请号：US11933872
申请日：2007-11-01
申请人： Loell Boyce Moon , Paul Haefner , Andres Belalcazar
发明人： Loell Boyce Moon , Paul Haefner , Andres Belalcazar
IPC分类号： A61B5/0205
CPC分类号： A61B5/0535 , A61B5/0809
摘要： A method of determining a value for a respiration parameter in a test subject can include capturing—using a fully implanted system that includes a wireless transmitter and at least a first lead wire having a first electrode disposed thereon and a second lead wire having a second electrode disposed thereon—information indicative of an impedance measure between the first and second electrodes and across a thoracic region of the test subject; wirelessly transmitting, from the implanted system and to external equipment, the captured information; and determining a respiration parameter of the test subject based on the captured information. The at least first and second lead wires can be positioned in the test subject subcutaneously and external of any cranial, thoracic, abdominal and pelvic cavities of the test subject
摘要翻译：确定测试对象中的呼吸参数的值的方法可以包括捕获 - 使用完全植入的系统，其包括无线发射器和至少第一引线，其具有设置在其上的第一电极和具有第二电极的第二引线布置在其上的信息 - 指示所述第一和第二电极之间以及穿过所述测试对象的胸部区域的阻抗测量值的信息; 从植入系统和外部设备无线传输所捕获的信息; 以及基于所捕获的信息确定所述测试对象的呼吸参数。至少第一和第二引线可以被测试对象的皮下和外部位于测试对象的任何颅脑，胸部，腹部和盆腔内

9. 发明申请

US20070123923A1 Implantable medical device minimizing rotation and dislocation 审中-公开
标题翻译：植入式医疗器械减少旋转和脱位
公开(公告)号：US20070123923A1
公开(公告)日：2007-05-31
申请号：US11290355
申请日：2005-11-30
申请人： Curtis Lindstrom , Ronald Heil , Jason Shiroff , Paul Haefner , Adam Cates , Darrell Wagner
发明人： Curtis Lindstrom , Ronald Heil , Jason Shiroff , Paul Haefner , Adam Cates , Darrell Wagner
IPC分类号： A61N1/375 , A61F2/04
CPC分类号： A61F2/0095 , A61N1/375
摘要： Housings for implantable medical devices are configured so as to engage with surrounding tissues inside of a body and resist both rotation in place and movement through the body. Device housings include shapes, surface features, and/or standard surfaces and may include attached implements that engage the surrounding tissue. Shapes include elongated members, flared ends, and so forth. Surface features include pores, grooves, through-holes, and so forth. Attached implements include needles, barbs, tension springs, and so forth. Also provided are methods for engaging an implantable medical device with surrounding tissues.
摘要翻译：用于可植入医疗装置的壳体构造成与身体内的周围组织接合并抵抗适当位置的旋转和穿过身体的运动。设备外壳包括形状，表面特征和/或标准表面，并且可以包括接合周围组织的附接工具。形状包括细长构件，扩口端等。表面特征包括孔，槽，通孔等。附件包括针，倒钩，拉伸弹簧等。还提供了用于使可植入医疗装置与周围组织接合的方法。

10. 发明申请

US20050038350A1 Biopotential signal source separation using source impedances 有权
标题翻译：使用源阻抗的生物电位信号源分离
公开(公告)号：US20050038350A1
公开(公告)日：2005-02-17
申请号：US10821206
申请日：2004-04-08
申请人： Apurv Kamath , Darrell Wagner , Paul Haefner , Marina Brockway
发明人： Apurv Kamath , Darrell Wagner , Paul Haefner , Marina Brockway
IPC分类号： A61B5/042 , A61B5/0428 , A61B5/0464 , A61N1/365 , A61N1/39 , A61B5/0402
CPC分类号： A61B5/0464 , A61B5/042 , A61B5/0428 , A61N1/36585 , A61N1/3956
摘要： Cardiac methods and devices that separate signals using at least two composite signals acquired at least at two input impedances. A target source impedance may be selected, and a cardiac signal may be separated from composite signals using the selected target source impedance. Medical systems include a cardiac device having a housing that provides amplification circuitry configured to have a first amplifier input impedance and a second amplifier input impedance, such as using two separate circuits or switching between two input impedances. One or more electrode assemblies are coupled to the amplification circuitry. A signal processor is provided in the housing configured to separate a source signal using a first composite signal detected at the first input impedance and a second composite signal detected at the second input impedance. The phase response of the first input amplifier circuit is about equal to that of the second input amplifier circuit.
摘要翻译：使用至少两个输入阻抗获取的至少两个复合信号分离信号的心脏方法和装置。可以选择目标源阻抗，并且可以使用所选择的目标源阻抗将心脏信号与复合信号分离。医疗系统包括具有壳体的心脏装置，其提供被配置为具有第一放大器输入阻抗和第二放大器输入阻抗的放大电路，例如使用两个分离的电路或在两个输入阻抗之间切换。一个或多个电极组件耦合到放大电路。信号处理器设置在壳体中，配置成使用在第一输入阻抗处检测到的第一复合信号和在第二输入阻抗处检测到的第二复合信号来分离源信号。第一输入放大器电路的相位响应大约等于第二输入放大器电路的相位响应。

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