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1. 发明申请

US20050137672A1 Myocardial lead 审中-公开
标题翻译：心肌铅
公开(公告)号：US20050137672A1
公开(公告)日：2005-06-23
申请号：US10972049
申请日：2004-10-22
申请人： M. Coe , Ronald Heil , Peter Kelley , Jason Shiroff , Randy Westlund , Donald Palme , David Yingling
发明人： M. Coe , Ronald Heil , Peter Kelley , Jason Shiroff , Randy Westlund , Donald Palme , David Yingling
IPC分类号： A61B5/0492 , A61B17/04 , A61B17/06 , A61N1/05
CPC分类号： A61B17/0469 , A61B5/0492 , A61B17/06109 , A61B2017/0417 , A61B2017/06042 , A61B2017/0608 , A61N1/0568 , A61N1/0587 , A61N2001/0578 , A61N2001/058
摘要： The present invention is a lead for use in connection with a myocardial lead attachment system of the type having an anchor for engaging the heart and a tether extending from the anchor. The lead includes a lead body having a proximal end, a distal end and a lumen for accepting the tether. A tapered tip is separate from the lead and positioned adjacent the distal end of the lead. The tip has a longitudinal through-hole for accepting the tether.
摘要翻译：本发明是一种用于与具有用于接合心脏的锚固件和从锚固件延伸的系绳的类型的心肌引线附接系统相关联的引线。引线包括具有近端，远端和用于接收系绳的内腔的引线体。锥形尖端与引线分离并且位于铅的远端附近。尖端具有用于接受系绳的纵向通孔。

2. 发明申请

US20050113900A1 Myocardial lead with fixation mechanism 有权
标题翻译：心肌导联与固定机制
公开(公告)号：US20050113900A1
公开(公告)日：2005-05-26
申请号：US10971549
申请日：2004-10-22
申请人： Jason Shiroff , Ronald Heil , Peter Kelley , M. Coe , Randy Westlund , Donald Palme , David Yingling
发明人： Jason Shiroff , Ronald Heil , Peter Kelley , M. Coe , Randy Westlund , Donald Palme , David Yingling
IPC分类号： A61B5/0492 , A61B17/04 , A61B17/06 , A61N1/05
CPC分类号： A61B17/0469 , A61B5/0492 , A61B17/06109 , A61B2017/0417 , A61B2017/06042 , A61B2017/0608 , A61N1/0568 , A61N1/0587 , A61N2001/0578 , A61N2001/058
摘要： The present invention is a myocardial lead attachment system and method for securing a distal end of a lead within the myocardium of a patient's heart. The system includes an anchor, a tether coupled at a distal end to the anchor and a lead body. The lead body has a proximal end, a distal end, and a lumen extending therethrough for receiving the tether. A fixation mechanism is at the distal end of the lead body, and is adapted to collapse to a first configuration during implantation and deploy to a second configuration after implantation.
摘要翻译：本发明是用于将铅的远端固定在患者心脏的心肌内的心肌引导附着系统和方法。该系统包括锚固件，在远端连接到锚固件的系绳和引线主体。引线本体具有近端，远端和延伸穿过其中的内腔，用于接收系绳。固定机构位于引线主体的远端，并且适于在植入期间折叠成第一构型并且在植入之后部署到第二构造。

3. 发明申请

US20060279907A1 METHOD AND APPARATUS FOR A CAPACITOR SHELL INCLUDING TWO MATEABLE CUPPED COMPONENTS 有权
标题翻译：一种电容器壳体的方法和装置，包括两个可用的组合部件
公开(公告)号：US20060279907A1
公开(公告)日：2006-12-14
申请号：US11423268
申请日：2006-06-09
申请人： Brian Doffing , James Taller , Gregory Sherwood , Jason Shiroff
发明人： Brian Doffing , James Taller , Gregory Sherwood , Jason Shiroff
IPC分类号： H01G9/08
CPC分类号： H01G9/10 , A61N1/3968 , H01G9/008 , H01G9/14 , Y10T29/417
摘要： One embodiment of the present subject matter includes a capacitor, comprising a first cupped shell having a first opening, and a second cupped shell having a second opening, wherein the first opening and the second opening are adapted to sealably mate to form a closed shell defining a volume therein. In the embodiment, the closed shell is adapted for retaining electrolyte. A plurality of capacitor layers in a substantially flat arrangement are disposed within the volume, along with electrolyte, in the present embodiment. The present closed shell includes one or more ports for electrical connections.
摘要翻译：本主题的一个实施例包括电容器，其包括具有第一开口的第一杯状壳体和具有第二开口的第二杯状壳体，其中第一开口和第二开口适于密封地配合以形成限定其中的体积。在该实施例中，封闭壳适于保持电解质。在本实施例中，基本平坦布置的多个电容器层与电解质一起设置在体积内。本封闭壳体包括用于电连接的一个或多个端口。

4. 发明申请

US20100268311A1 Method for Implanting Electrode on Nerve 审中-公开
标题翻译：神经内植入电极的方法
公开(公告)号：US20100268311A1
公开(公告)日：2010-10-21
申请号：US12761956
申请日：2010-04-16
申请人： Ralph Cardinal , Jason Skubitz , Jason Shiroff , Johann Neisz
发明人： Ralph Cardinal , Jason Skubitz , Jason Shiroff , Johann Neisz
IPC分类号： A61N1/05
CPC分类号： A61N1/0556
摘要： Methods and devices for implanting an electrode near a nerve covered by a tissue layer or layers. Methods can include cutting through a tissue layer covering the nerve to form at least two exposed pleural tissue layer edges. The nerve can be freed from any tissue around the nerve and the electrode placed around the nerve. The pleura edges can be drawn toward each other to cover the nerve and the edges secured together. Some methods form two tissue flaps which are pulled away from each other to expose the nerve. Other methods form a single tissue flap which extends over the nerve and is pulled back to expose the nerve. The now covered nerve is protected against movement of tissues near the now covered nerve. Such methods find one use in placing electrodes near the splanchnic nerves in the thoracic cavity, where the lung and diaphragm may contact an exposed electrode.
摘要翻译：用于将电极植入靠近由组织层或多层覆盖的神经的方法和装置。方法可以包括穿过覆盖神经的组织层以形成至少两个暴露的胸膜组织层边缘。神经可以从神经周围的任何组织和置于神经周围的电极中释放出来。胸膜边缘可以朝向彼此拉伸以覆盖神经和固定在一起的边缘。一些方法形成两个组织瓣，其彼此拉开以暴露神经。其他方法形成一个单一的组织瓣，其在神经上延伸并被拉回以暴露神经。现在被覆盖的神经受到保护，防止现在被覆盖的神经附近的组织移动。这种方法可用于将电极放置在胸腔内的内脏神经附近，其中肺和隔膜可接触暴露的电极。

5. 发明申请

US20070010793A1 Method and system for accessing a pericardial space 审中-公开
标题翻译：用于获取心包空间的方法和系统
公开(公告)号：US20070010793A1
公开(公告)日：2007-01-11
申请号：US11159705
申请日：2005-06-23
申请人： Peter Callas , Gary Hague , John Greenland , Bruce Tockman , Peter Kelley , Jason Shiroff , David Yingling , Ted Schulte
发明人： Peter Callas , Gary Hague , John Greenland , Bruce Tockman , Peter Kelley , Jason Shiroff , David Yingling , Ted Schulte
IPC分类号： A61M31/00
CPC分类号： A61B17/3478 , A61B2017/306 , A61M25/0084
摘要： A device and method for accessing a pericardial space of the heart includes a shaft having a cavity at a distal end, a suction lumen terminating in a distal port within the cavity and a hollow needle having a distal tip extending into the cavity. The cavity may be a recess in the shaft into which the distal tip of the needle fixedly protrudes. In other embodiments, the cavity is formed by an inflatable member positioned at the distal end of the shaft and the needle is slidable relative to the shaft. Suction is applied at the cavity to draw a pericardial bleb. The needle pierces the pericardial bleb for accessing the pericardial space and also facilitates delivery of payloads into the pericardial space.
摘要翻译：用于访问心脏心包空间的装置和方法包括：具有在远端处的空腔的轴，位于空腔内的远端端口中的抽吸腔，以及具有延伸到空腔中的远端的中空针。空腔可以是轴中的凹部，其中针的远侧末端固定地突出。在其他实施例中，空腔由位于轴的远端处的可充气构件形成，并且针可相对于轴滑动。在空腔处抽取吸入心包泡。针刺穿心包泡，用于进入心包空间，并且还有助于将载荷递送到心包空间中。

6. 发明申请

US20050137674A1 Distal or proximal fixation of over-the-tether myocardial leads 有权
标题翻译：远端或近端固定超过系绳心肌引线
公开(公告)号：US20050137674A1
公开(公告)日：2005-06-23
申请号：US10972298
申请日：2004-10-22
申请人： M. Coe , Ronald Heil , Peter Kelley , Jason Shiroff , Randy Westlund , Donald Palme
发明人： M. Coe , Ronald Heil , Peter Kelley , Jason Shiroff , Randy Westlund , Donald Palme
IPC分类号： A61N1/05
CPC分类号： A61N1/0587 , A61N2001/0578
摘要： The present invention is a myocardial lead attachment system for securing a lead within the myocardium. The attachment system includes an anchor configured to engage the heart, a tether coupled to the anchor and a lead body. The lead body has a proximal end, a distal end, a lumen for accepting the tether and a lock housing in the lumen. A lock structure is on the tether and mates with the lock housing and restrains motion of the lead with respect to the tether in either of a proximal or a distal direction.
摘要翻译：本发明是用于将铅固定在心肌内的心肌引导附着系统。附接系统包括构造成接合心脏的锚，连接到锚固体的系绳和引导体。引线体具有近端，远端，用于接纳系绳的内腔和在内腔中的锁定壳体。锁定结构位于系绳上并且与锁定壳体配合并且在近端或远端方向中抑制引线相对于系绳的运动。

7. 发明申请

US20050119718A1 Absorbable myocardial lead fixation system 有权
标题翻译：可吸收心肌引导固定系统
公开(公告)号：US20050119718A1
公开(公告)日：2005-06-02
申请号：US10971577
申请日：2004-10-22
申请人： M. Sean Coe , Ronald Heil , Peter Kelley , Jason Shiroff , Randy Westlund , Donald Palme
发明人： M. Sean Coe , Ronald Heil , Peter Kelley , Jason Shiroff , Randy Westlund , Donald Palme
IPC分类号： A61B5/0492 , A61B17/04 , A61B17/06 , A61N1/05
CPC分类号： A61B17/0469 , A61B5/0492 , A61B17/06109 , A61B2017/0417 , A61B2017/06042 , A61B2017/0608 , A61N1/0568 , A61N1/0587 , A61N2001/0578 , A61N2001/058
摘要： A myocardial lead attachment system for securing a distal end of a lead within a myocardium of a patient's heart. The system includes a lead body, an anchor mechanism formed of a bioabsorbable or biodegradable polymer for engaging a surface of the patient's heart and a surface feature formed on a portion of the lead body for promoting formation of scar tissue around said portion of the lead body.
摘要翻译：用于将铅的远端固定在患者心脏的心肌内的心肌引线附着系统。该系统包括引线体，由生物可吸收或可生物降解的聚合物形成的锚固机构，用于接合患者心脏的表面，以及形成在引线体的一部分上的表面特征，用于促进在引线体的所述部分周围形成瘢痕组织。

8. 发明授权

US08612025B2 Cuff electrode having tubular body with controlled closing force 有权
标题翻译：具有具有受控闭合力的管状体的袖带电极
公开(公告)号：US08612025B2
公开(公告)日：2013-12-17
申请号：US13413509
申请日：2012-03-06
申请人： Hans Neisz , Ralph Cardinal , Jason Shiroff , Jason John Skubitz
发明人： Hans Neisz , Ralph Cardinal , Jason Shiroff , Jason John Skubitz
IPC分类号： A61N1/04
CPC分类号： A61N1/0556
摘要： Nerve cuff electrode including a tubular body having a longitudinal slit and a flap curled over the slit. The tubular body includes a central cathode disposed between two anodes. The region opposite the slit includes a flexible region that determines the flexibility and strength of tube opening and closing. The cuff electrode having a hinge region with a non-linear effective spring constant which can be higher at low cuff openings and lower at large opening to provide an effective yet non-damaging closing force over a wide range of cuff openings. In use, the tube body can be pulled apart using attached suture loops, with one loop and flap pulled under the nerve followed by part of the tubular body. The tubular body can be closed over the nerve and the flap closed over the tube slit.
摘要翻译：神经袖口电极包括具有纵向狭缝的管状体和在狭缝上卷曲的舌片。管状体包括设置在两个阳极之间的中心阴极。狭缝相对的区域包括确定管的开启和关闭的灵活性和强度的柔性区域。袖带电极具有非线性有效弹簧常数的铰链区域，其可以在低袖口开口处较高，而在大开口处较低，从而在宽范围的袖口开口处提供有效但无损伤的关闭力。在使用中，管体可以使用附接的缝线环被拉开，一个环和翼片拉在神经下面，然后是管状体的一部分。管状体可以在神经上闭合，并且瓣在封闭管狭缝上。

9. 发明申请

US20120197371A1 CUFF ELECTRODE HAVING TUBULAR BODY WITH CONTROLLED CLOSING FORCE 有权
标题翻译：具有控制闭合力的管状体的CUFF电极
公开(公告)号：US20120197371A1
公开(公告)日：2012-08-02
申请号：US13413509
申请日：2012-03-06
申请人： Hans Neisz , Ralph Cardinal , Jason Shiroff , Jason John Skubitz
发明人： Hans Neisz , Ralph Cardinal , Jason Shiroff , Jason John Skubitz
IPC分类号： A61N1/05
CPC分类号： A61N1/0556
摘要： Nerve cuff electrode including a tubular body having a longitudinal slit and a flap curled over the slit. The tubular body includes a central cathode disposed between two anodes. The region opposite the slit includes a flexible region that determines the flexibility and strength of tube opening and closing. The cuff electrode having a hinge region with a non-linear effective spring constant which can be higher at low cuff openings and lower at large opening to provide an effective yet non-damaging closing force over a wide range of cuff openings. In use, the tube body can be pulled apart using attached suture loops, with one loop and flap pulled under the nerve followed by part of the tubular body. The tubular body can be closed over the nerve and the flap closed over the tube slit.
摘要翻译：神经袖口电极包括具有纵向狭缝的管状体和在狭缝上卷曲的舌片。管状体包括设置在两个阳极之间的中心阴极。狭缝相对的区域包括确定管的开启和关闭的灵活性和强度的柔性区域。袖带电极具有非线性有效弹簧常数的铰链区域，其可以在低袖口开口处较高，而在大开口处较低，从而在宽范围的袖口开口处提供有效但无损伤的关闭力。在使用中，管体可以使用附接的缝线环被拉开，一个环和翼片拉在神经下面，然后是管状体的一部分。管状体可以在神经上闭合，并且瓣在封闭管狭缝上。

10. 发明授权

US08155757B1 Cuff electrode having tubular body with controlled closing force 有权
标题翻译：具有具有受控闭合力的管状体的袖带电极
公开(公告)号：US08155757B1
公开(公告)日：2012-04-10
申请号：US12181214
申请日：2008-07-28
申请人： Hans Neisz , Ralph Cardinal , Jason Shiroff , Jason John Skubitz
发明人： Hans Neisz , Ralph Cardinal , Jason Shiroff , Jason John Skubitz
IPC分类号： A61N1/04
CPC分类号： A61N1/0556
摘要： Nerve cuff electrodes and methods using nerve cuffs. Nerve cuff electrodes are provided which can include a tubular body having a longitudinal slit and a flap curled over the slit. The tubular body interior can have a central cathode formed of two opposed and electrically coupled plates disposed between two anodes each formed of two opposed and electrically coupled plates. The tube interior region opposite the slit can be free of electrode material, such that the flexibility of the polymeric tube significantly determines the flexibility and strength of tube opening and closing. Some cuffs include a hinge region having a non-linear effective spring constant which can be higher at low cuff openings and lower at large opening to provide an effective yet non-damaging closing force over a wide range of cuff openings. In use, the tube body can be pulled apart using attached suture loops, with one loop and flap pulled under the nerve followed by part of the tubular body. The tubular body can be closed over the nerve and the flap closed over the tube slit. The nerve cuff can be placed minimally invasively over the nerve and used for neuromodulation and/or sensing purposes.
摘要翻译：神经袖口电极和使用神经袖口的方法。提供神经袖口电极，其可以包括具有纵向狭缝的管状体和在狭缝上卷曲的舌片。管状体内部可以具有由两个相对的和电耦合的板形成的中心阴极，该两个相对的和电耦合的板设置在由两个相对的和电耦合的板形成的两个阳极之间与狭缝相对的管内部区域可以没有电极材料，使得聚合物管的柔性显着地决定了管的开启和关闭的灵活性和强度。一些袖口包括具有非线性有效弹簧常数的铰链区域，其可在低袖口开口处较高并且在大开口处较低，以在宽范围的袖口开口处提供有效但无损伤的闭合力。在使用中，管体可以使用附接的缝线环被拉开，一个环和翼片拉在神经下面，然后是管状体的一部分。管状体可以在神经上闭合，并且瓣在封闭管狭缝上。神经袖口可以最小程度地隐藏在神经上并用于神经调节和/或感测目的。

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