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1. 发明授权

US6143850A Lipophilic polymeric UV absorbers 有权
标题翻译：亲脂性聚合物紫外线吸收剂
公开(公告)号：US6143850A
公开(公告)日：2000-11-07
申请号：US131391
申请日：1998-08-07
申请人： Harald Keller , Volker Schehlmann , Horst Westenfelder , Thomas Preiss
发明人： Harald Keller , Volker Schehlmann , Horst Westenfelder , Thomas Preiss
IPC分类号： A61K8/00 , A61K8/90 , A61Q1/00 , A61Q1/04 , A61Q5/00 , A61Q17/04 , C08F216/14 , C08F216/18 , C08F218/00 , C08F218/10 , C08F220/36 , C09K3/00 , C08F20/58
CPC分类号： C08F218/00 , A61K8/90 , A61Q1/04 , A61Q17/04 , C08F216/18
摘要： Polymeric UV absorbers based on the units shown in the schematized formula I ##STR1## where the sequence of the units is arbitrary, the sum of a+b+c+d=100 anda is a value from 5 to 95,b is a value from 0 to 70,c is a value from 5 to 95,d is a value from 0 to 70and the radicals R have the meaning explained in the description, are described.
摘要翻译：聚合紫外吸收剂基于所示单位所示的单位，其中单元的序列是任意的，a + b + c + d = 100的和和a是5至95的值，b是0 至70，c为5至95的值，d为0至70的值，基团R具有在说明书中说明的含义。

2. 发明授权

US06238649B1 Cosmetic and pharmaceutical preparations containing photostable UV filters 有权
标题翻译：含有光稳定紫外线过滤器的化妆品和药物制剂
公开(公告)号：US06238649B1
公开(公告)日：2001-05-29
申请号：US09133173
申请日：1998-08-13
申请人： Thorsten Habeck , Sylke Haremza , Volker Schehlmann , Horst Westenfelder , Thomas Wünsch , Michael Drögemüller , Volker Bomm
发明人： Thorsten Habeck , Sylke Haremza , Volker Schehlmann , Horst Westenfelder , Thomas Wünsch , Michael Drögemüller , Volker Bomm
IPC分类号： A61K742
CPC分类号： C07C235/34 , A61K8/35 , A61K8/37 , A61K8/40 , A61K8/42 , A61K31/12 , A61K31/122 , A61K31/216 , A61K31/277 , A61K2800/52 , A61Q1/04 , A61Q17/04 , C07C69/618 , C07C233/11
摘要： 4,4-Diarylbutadienes of the formula I, where the variables have the meanings explained in the description, are used as photostable UV filters in cosmetic and pharmaceutical preparations to protect the human skin or human hair from the sun's rays, alone or together with compounds which absorb in the UV region and are known per se for cosmetic and pharmaceutical preparations.
摘要翻译：式I中的4,4-二芳基丁二烯，其中变量具有说明书中解释的含义，用作化妆品和药物制剂中的光稳定性UV过滤器，以单独或与化合物一起保护人皮肤或人类头发免受太阳光线其在UV区域中吸收并且本身已知化妆品和药物制剂。

3. 发明授权

US5945091A Photo-stable cosmetic and pharmaceutical formulations containing UV-filters 失效
标题翻译：光稳定的化妆品和药物配方含有紫外线过滤器
公开(公告)号：US5945091A
公开(公告)日：1999-08-31
申请号：US972391
申请日：1997-11-18
申请人： Thorsten Habeck , Alexander Aumuller , Volker Schehlmann , Horst Westenfelder , Thomas Wunsch
发明人： Thorsten Habeck , Alexander Aumuller , Volker Schehlmann , Horst Westenfelder , Thomas Wunsch
IPC分类号： A61K8/30 , A61K8/00 , A61K8/41 , A61K8/42 , A61K8/46 , A61K8/49 , A61Q1/00 , A61Q1/04 , A61Q17/04 , A61Q19/00 , C07C229/56 , C07C229/60 , C07C255/30 , C07C255/58 , C07C309/46 , C07D275/02 , C07D275/03 , C07D319/06 , C07D333/38 , A61K7/42 , A61K7/00 , A61K31/255 , A61K31/275 , A61K31/66
CPC分类号： C07D275/03 , A61K8/411 , A61K8/42 , A61K8/466 , A61K8/49 , A61K8/498 , A61K8/4986 , A61Q1/04 , A61Q17/04 , C07C229/56 , C07C229/60 , C07C255/30 , C07C255/58 , C07C309/46 , C07D319/06 , C07D333/38 , A61K2800/52
摘要： A method of using compounds of formula I ##STR1## in which the C.dbd.C double bond is present in E and/or Z configuration and the variables have the following meanings:R.sup.1 denotes COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN, O.dbd.S(--R.sup.5).dbd.O, O.dbd.S(--OR.sup.5).dbd.O, R.sup.7 O--P(--OR.sup.8).dbd.O;R.sup.2 denotes COOR.sup.6, COR.sup.6, CONR.sup.5 R.sup.6, CN, O.dbd.S(--R.sup.6).dbd.O, O.dbd.S(--OR.sup.6).dbd.O, R.sup.7 O--P(--OR.sup.8).dbd.O;R.sup.3 denotes hydrogen, an optionally substituted aliphatic, cycloaliphatic, araliphatic or aromatic radical having in each case up to 18 carbon atoms;R.sup.4 denotes an optionally substituted aromatic or heteroaromatic radical containing from 5 to 12 ring atoms;R.sup.5 toR.sup.8 independently denote hydrogen, an open-chain or branched-chain aliphatic, araliphatic, cycloaliphatic or optionally substituted aromatic radical containing in each case up to 18 carbon atoms,where the variables R.sup.3 to R.sup.8 may also form, together with the carbon atoms to which they are attached, a 5-membered or 6-membered ring, which may be anellated if desired,as UV filters, particularly UV-A filters, in cosmetic and pharmaceutical formulations for the protection of the human skin or human hair from solar radiation, alone or together with compounds known per se in cosmetic and pharmaceutical formulations and capable of absorbing radiation in the UV range.
摘要翻译：在E和/或Z构型中使用存在C = C双键的式I化合物的方法，并且变量具有以下含义：R 1表示COOR 5，COR 5，CONR 5 R 6，CN，O = S（-R 5） = O，O = S（-OR 5）= O，R 7 O-P（-OR 8）= O; R2表示COOR6，COR6，CONR5R6，CN，O = S（-R6）= O，O = S（-OR6）= O，R7O-P（-OR8）= O; R 3表示氢，任选取代的脂族，脂环族，芳脂族或芳族基团，其在每种情况下最多为18个碳原子; R4表示任选取代的芳族或杂芳族基团，其含有5至12个环原子; R5至R8独立地表示氢，开链或支链脂族，芳脂族，脂环族或任选取代的芳族基团，其在每种情况下含有至多18个碳原子，其中变量R3至R8也可与碳原子一起形成它们所连接的是5元或6元环，如果需要，可以作为UV过滤剂，特别是UV-A过滤器，在用于保护人类皮肤或人类头发免受太阳能的化妆品和药物制剂中的影响单独或与化妆品和药物制剂中本身已知的化合物一起辐射并且能够吸收UV范围内的辐射。

4. 发明申请

US20070189994A1 Light protecting composition with reduced total amount of uv filter containing a polysiloxane-based uv filter 审中-公开
标题翻译：含有聚硅氧烷基紫外线过滤器的紫外线过滤器总量减少的光保护组合物
公开(公告)号：US20070189994A1
公开(公告)日：2007-08-16
申请号：US10578792
申请日：2004-10-28
申请人： Katja Berg , Thomas Rudolph , Volker Schehlmann , Christina Traeger , Horst Westenfelder
发明人： Katja Berg , Thomas Rudolph , Volker Schehlmann , Christina Traeger , Horst Westenfelder
IPC分类号： A61K8/49 , A61K8/89 , A61K8/37 , A61K8/35 , A61K8/29 , A61K8/27
CPC分类号： A61K8/89 , A61K8/27 , A61K8/29 , A61K8/35 , A61K8/445 , A61K8/496 , A61K8/893 , A61K2800/57 , A61Q17/04
摘要： The present invention is directed to a lightprotecting composition containing at least one polysiloxane-based UV filter. The composition has an increased ratio of the sunprotecting factor to the total UV filter amount. This is achieved by the combination with at least one UV filter which chromophore contains appropriate bulky (sterically demanding) substituents as steric protection groups.
摘要翻译：本发明涉及含有至少一种基于聚硅氧烷的UV滤光片的防光组合物。该组合物具有增加的防晒因子与总UV过滤量的比率。这通过与至少一个UV滤光片的组合来实现，其中发色团含有作为空间保护基团的适当大体积（空间要求）的取代基。

5. 发明授权

US5968484A Cosmetic preparations comprising photostable UV-A filters 失效
公开(公告)号：US5968484A
公开(公告)日：1999-10-19
申请号：US916361
申请日：1997-08-22
申请人： Thorsten Habeck , Alexander Aumueller , Volker Schehlmann , Horst Westenfelder , Thomas Wunsch
发明人： Thorsten Habeck , Alexander Aumueller , Volker Schehlmann , Horst Westenfelder , Thomas Wunsch
IPC分类号： A61K8/00 , A61K8/30 , A61K8/40 , A61K8/49 , A61K8/92 , A61Q1/00 , A61Q1/04 , A61Q17/04 , C07C255/40 , C07D307/52 , C07D317/54 , C07D333/24 , A61K7/42 , A61K7/00 , C07C255/03
CPC分类号： C07C255/40 , A61K8/40 , A61K8/4973 , A61K8/4986 , A61Q1/04 , A61Q17/04 , C07D317/54 , C07D333/24 , A61K2800/52 , A61Q19/001
摘要： A cosmetic preparation which comprises a sunscreen agent for protecting the human epidermis against UV light in the range from 280 to 400 nm, which comprises, in a cosmetically suitable carrier, alone or together with compounds which absorb in the UV region and are known for cosmetic preparations, as photostable UV-A filters, effective amounts of compounds of the formula I ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are hydrogen or aliphatic or cycloaliphatic radicals each having up to 18 carbon atoms, it being possible for any two of the radicals R.sup.1, R.sup.2 and R.sup.3 together to form a 5- or 6-membered ring, and R.sup.4 and R.sup.5 are an unsubstituted or substituted aromatic or heteroaromatic radical having 5 to 12 ring atoms, and R.sup.5 can additionally be hydrogen.

6. 发明授权

US5932195A Arylaminomethylenecamphor derivatives 失效
标题翻译：芳基亚甲基am卟啉衍生物
公开(公告)号：US5932195A
公开(公告)日：1999-08-03
申请号：US6175
申请日：1998-01-13
申请人： Michael Drogemuller , Volker Bomm , Volker Schehlmann , Horst Westenfelder
发明人： Michael Drogemuller , Volker Bomm , Volker Schehlmann , Horst Westenfelder
IPC分类号： C07D215/42 , A61K8/00 , A61Q17/04 , C07C225/14 , C07C229/54 , C07C237/30 , C07C309/46 , C07C311/39 , C09K3/00 , A61K7/42 , A61K7/44 , C07C229/56
CPC分类号： C07C225/14 , C07C2102/42
摘要： Arylaminomethylenecamphor derivatives of the formula (1) ##STR1## where the C.dbd.C double bond is in the Z or E configuration, and the variables have the following meanings:R.sup.1 H, CH.sub.3,R.sup.2 H, C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.3 -C.sub.8 -cycloalkenyl, aryl or substituted aryl,R.sup.3 H, C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.8 -cycloalkyl, aryl, substituted aryl, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.8 -acyl,Ar aryl, substituted aryl, hetaryl or substituted hetaryl,are used as sunscreen agents, especially in cosmetic and pharmaceutical formulations.
摘要翻译：其中C = C双键为Z或E构型的式（1）的芳基亚氨基亚甲基am卟啉衍生物，并且变量具有以下含义：R 1 H，CH 3，R 2 H，C 1 -C 6烷基，C 3 -C 8 - 环烷基，C 2 -C 6 - 烯基，C 3 -C 8 - 环烯基，芳基或取代的芳基，R 3 H，C 1 -C 6 - 烷基，C 3 -C 8 - 环烷基，芳基，取代的芳基，C 1 -C 6 - 烷氧基，C 1 -C 8酰基， Ar芳基，取代芳基，杂芳基或取代的杂芳基用作防晒剂，特别是在化妆品和药物制剂中。

7. 发明申请

US20060073106A1 Novel stabilized cinnamic ester sunscreen compositions 审中-公开
标题翻译：新型稳定的肉桂酯防晒组合物
公开(公告)号：US20060073106A1
公开(公告)日：2006-04-06
申请号：US10542927
申请日：2003-09-25
申请人： Katja Berg-Schultz , Volker Schehlmann , Horst Westenfelder
发明人： Katja Berg-Schultz , Volker Schehlmann , Horst Westenfelder
IPC分类号： A61K8/37
CPC分类号： A61K8/11 , A61K8/37 , A61K2800/52 , A61Q17/04
摘要： The invention relates to a method of enhancing the photostability of an encapsulated cinnamate derivative in a topical sunscreen composition which comprises introducing into such sunscreen composition an effective amount of at least one additional non-encapsulated sunscreen.
摘要翻译：本发明涉及增强局部防晒组合物中包封的肉桂酸酯衍生物的光稳定性的方法，该方法包括向这种防晒组合物中引入有效量的至少一种另外未包封的防晒剂。

8. 发明授权

US06210657B1 Use of isoindolinone derivatives as stabilizers for organic materials 失效
标题翻译：异吲哚啉酮衍生物作为有机材料的稳定剂的使用
公开(公告)号：US06210657B1
公开(公告)日：2001-04-03
申请号：US09207624
申请日：1998-12-09
申请人： Thorsten Habeck , Sylke Haremza , Hubert Trauth , Volker Schehlmann , Horst Westenfelder
发明人： Thorsten Habeck , Sylke Haremza , Hubert Trauth , Volker Schehlmann , Horst Westenfelder
IPC分类号： A61K742
CPC分类号： A61K31/4035 , C08K5/3417 , C09D7/48 , C09K15/30 , Y10S514/844 , Y10S514/97 , Y10S514/972
摘要： Isoindolinone derivatives of the formula I, in which the variables have the following meanings: R1 is hydrogen, COOR4, COR4, CONR4R5, CN, C1-C20-alkyl, C2-C10-alkenyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl, aryl or heteroaryl, substituted or unsubstituted; R1 and R2 together are C7-C10-bicycloalkyl or C7-C10-bicycloalkenyl; R3 is hydrogen, C1-C20-alkyl, C2-C10-alkenyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl, C1-C12-alkoxy, C1-C20-alkoxycarbonyl, C1-C12-alkylamino, C1-C12-dialkylamino, aryl or heteroaryl, substituted or unsubstituted, substituents which confer solubility in water, selected from the group consisting of carboxylate, sulfonate or ammonium radicals; R4 and R5 independently of one another are hydrogen, C1-C20-alkyl, C2-C10-alkenyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl; aryl or heteroaryl, substituted or unsubstituted; are used as stabilizers for organic materials.
摘要翻译：式I的异吲哚啉酮衍生物，其中变量具有以下含义：R1是氢，COOR4，COR4，CONR4R5，CN，C1-C20-烷基，C2-C10-烯基，C3-C10-环烷基，C3-C10- 环烯基，芳基或杂芳基，取代或未取代的; R1和R2一起是C7-C10-双环烷基或C7-C10-双环烯基; R3是氢，C1-C20-烷基，C2-C10-烯基，C3-C10-环烷基，C3 -C 10 - 环烯基，C 1 -C 12 - 烷氧基，C 1 -C 20 - 烷氧基羰基，C 1 -C 12 - 烷基氨基，C 1 -C 12 - 二烷基氨基，芳基或杂芳基，取代或未取代的赋予水溶性的取代基，羧酸酯，磺酸酯或铵基; R 4和R 5彼此独立地是氢，C 1 -C 20 - 烷基，C 2 -C 10 - 烯基，C 3 -C 10 - 环烷基，C 3 -C 10 - 环烯基; 芳基或杂芳基，取代或未取代的;被用作有机材料的稳定剂。

9. 发明授权

US6090374A Cosmetic and pharmaceutical preparations comprising photostable UV filters 失效
标题翻译：包含光稳定型紫外线过滤器的化妆品和药物制剂
公开(公告)号：US6090374A
公开(公告)日：2000-07-18
申请号：US172672
申请日：1998-10-15
申请人： Thorsten Habeck , Sylke Haremza , Volker Schehlmann , Horst Westenfelder , Thomas Wunsch
发明人： Thorsten Habeck , Sylke Haremza , Volker Schehlmann , Horst Westenfelder , Thomas Wunsch
IPC分类号： A61K8/00 , A61K8/40 , A61K31/00 , A61P17/00 , A61P17/16 , A61Q1/04 , A61Q17/04 , A61K7/42 , A61K7/00 , A61K7/44
CPC分类号： A61Q17/04 , A61K8/40 , A61Q1/04 , A61K2800/52
摘要： The use of substituted .alpha.-methylstyrene derivatives of the formula I, ##STR1## where the variables have the following meanings: R.sup.1 C.sub.4 -C.sub.10 -alkoxy, C.sub.1 -C.sub.12 -alkylamino, C.sub.1 -C.sub.12 -dialkylamino, substituents which confer solubility in water and which are selected from the group consisting of carboxylate, sulfonate or ammonium residues;R.sup.2 hydrogen, C.sub.2 -C.sub.10 -alkyl, C.sub.1 -C.sub.12 -alkoxy;R.sup.3 COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN;R.sup.4 COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN; where the substituents R.sup.3 and R.sup.4 are identical in each case;R.sup.5 andR.sup.6 independently of one another hydrogen, C.sub.1 -C.sub.12 -alkyl, C.sub.2 -C.sub.10 -alkenyl, C.sub.3 -C.sub.10 -cycloalkyl, C.sub.3 -C.sub.10 -cycloalkenyl, aryl, hetaryl, unsubstituted or substituted;as photostable UV filters in cosmetic and pharmaceutical preparations to protect the human skin or human hair from the sun's rays, alone or together with UV-absorbing compounds known per se for cosmetic and pharmaceutical preparations.
摘要翻译：使用式I的取代的α-甲基苯乙烯衍生物，其中变量具有以下含义：R 1 C 4 -C 10 - 烷氧基，C 1 -C 12 - 烷基氨基，C 1 -C 12 - 二烷基氨基，赋予在水中溶解度并且被选择的取代基由羧酸盐，磺酸盐或铵残基组成的组; R2氢，C2-C10-烷基，C1-C12-烷氧基; R3 COOR5，COR5，CONR5R6，CN; R4 COOR5，COR5，CONR5R6，CN; 其中取代基R 3和R 4在每种情况下相同; R 5和R 6彼此独立地为氢，C 1 -C 12 - 烷基，C 2 -C 10 - 烯基，C 3 -C 10 - 环烷基，C 3 -C 10 - 环烯基，芳基，杂芳基，未取代或取代的; 作为化妆品和药物制剂中的光稳定紫外线过滤器，用于保护人体皮肤或人体毛发免受太阳光线的照射，或者与本身已知的用于化妆品和药物制剂的紫外线吸收化合物一起使用。

10. 发明授权

US06407247B1 Photo-stable cosmetic and pharmaceutical formulations containing UV-filters 失效
标题翻译：光稳定的化妆品和药物配方含有紫外线过滤器
公开(公告)号：US06407247B1
公开(公告)日：2002-06-18
申请号：US09494474
申请日：2000-01-31
申请人： Thorsten Habeck , Alexander Aumüller , Volker Schehlmann , Horst Westenfelder , Thomas Wünsch
发明人： Thorsten Habeck , Alexander Aumüller , Volker Schehlmann , Horst Westenfelder , Thomas Wünsch
IPC分类号： C07D22102
CPC分类号： C07D275/03 , A61K8/411 , A61K8/42 , A61K8/466 , A61K8/49 , A61K8/498 , A61K8/4986 , A61Q1/04 , A61Q17/04 , C07C229/56 , C07C229/60 , C07C255/30 , C07C255/58 , C07C309/46 , C07D319/06 , C07D333/38
摘要： A method of using compounds of formula I in which the C═C double bond is present in E and/or Z configuration and the variables have the following meanings: R1 denotes COOR5, COR5, CONR5R6, CN, O═S(—R5)═O, O═S(═OR5)═O, R7O—P(—OR8)═O; R2 denotes COOR6, COR6, CONR5R6, CN, O═S(—R6)═O, O═S(═OR6)═O, R7O—P(—OR8)═O; R3 denotes hydrogen, an optionally substituted aliphatic, cycloaliphatic, araliphatic or aromatic radical having in each case up to 18 carbon atoms; R4 denotes an optionally substituted aromatic or heteroaromatic radical containing from 5 to 12 ring atoms; R5 to R8 independently denote hydrogen, an open-chain or branched-chain aliphatic, araliphatic, cycloaliphatic or optionally substituted aromatic radical containing in each case up to 18 carbon atoms, where the variables R3 to R8 may also form, together with the carbon atoms to which they are attached, a 5-membered or 6-membered ring, which may be anellated if desired, as UV filters, particularly UV-A filters, in cosmetic and pharmaceutical formulations for the protection of the human skin or human hair from solar radiation, alone or together with compounds known per se in cosmetic and pharmaceutical formulations and capable of absorbing radiation in the UV range.
摘要翻译：在E和/或Z构型中使用存在C = C双键的式Iin化合物的方法，并且变量具有以下含义：R 1表示COOR 5，COR 5，CONR 5 R 6，CN，O = S（-R 5）= O = S（= OR5）= O，R7O-P（-OR8）= O; R2表示COOR6，COR6，CONR5R6，CN，O = S（-R6）= O，O = S（= OR6）= O，R7O-P（-OR8）= O; R3表示氢，任选取代的脂族，脂环族，芳脂族或芳族基团，其中每种情况下最多可达18个碳原子; R4表示任选取代的芳族或杂芳族基团， 12个环原子; R5至R8独立地表示氢，开链或支链脂族，芳脂族，脂环族或任选取代的芳族基团，其中每种情况最多可包含18个碳原子，其中变量R3至R8也可以形成，它们所连接的碳原子，5元或6元环，如果需要，可以将其作为UV滤光器，特别是UV-A滤光器，在化妆品和药物中用于保护人类皮肤或人类头发免受太阳辐射，单独或与化妆品和药物制剂中本身已知的化合物一起并且能够吸收UV范围内的辐射。

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