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    • 3. 发明申请
    • APPARATUS AND METHOD FOR MULTI-MODAL IMAGING USING NANOPARTICLE MULTI-MODAL IMAGING PROBES
    • 使用纳米尺度多模式成像探针进行多模式成像的装置和方法
    • US20090086908A1
    • 2009-04-02
    • US12196300
    • 2008-08-22
    • John William HarderDavid L. PattonShiying ZhengRuizheng WangJoseph Francis BringleyDouglas Lincoln VizardWilliam E. McLaughlinHeidi HallMark E. Bridges
    • John William HarderDavid L. PattonShiying ZhengRuizheng WangJoseph Francis BringleyDouglas Lincoln VizardWilliam E. McLaughlinHeidi HallMark E. Bridges
    • G01N23/04G03B42/02
    • A61B6/00A61B5/0035A61B5/0059A61B6/4216A61B6/4417A61B6/481A61B6/508A61B2503/40A61B2562/0242
    • An apparatus for multimodal imaging of an object includes a support stage for receiving an object to be imaged; an object supported on the stage, the object having been treated with a biocompatible imaging probe comprising nanoparticles carrying one or more targeting moieties and one or more diagnostic components for enabling capture of images of the object; a light source for producing a beam to illuminate the object; a filter positioned to receive and pass the beam toward the object; and a lens and camera system for capturing an image of the object. The apparatus may include a tiltable filter for filtering light from the source. The apparatus may include a mechanism for selectively directing light from the light source through a first filter assembly to produce a first beam of light of a first frequency range for illuminating an object on the stage in a first imaging mode or through a second filter assembly to produce a second beam of light of a second frequency range for illuminating an object on the stage in a second imaging mode, so that the lens and camera system captures light from the object illuminated by either the first or second beam of light to produce a first image in response to the first beam and a second image, different from the first image, in response to the second image. An x-ray source and phosphor plate may be included to provide an additional imaging mode.
    • 用于物体的多模式成像的装置包括用于接收待成像对象的支撑台; 支撑在舞台上的物体,已经用生物相容性成像探针处理了物体,所述生物相容性成像探针包含携带一个或多个靶向部分的纳米颗粒和一个或多个诊断部件,用于能够捕获物体的图像; 用于产生用于照射物体的光束的光源; 定位成接收并将光束传递到物体的过滤器; 以及用于捕获对象的图像的镜头和相机系统。 该装置可以包括用于过滤来自源的光的可倾斜滤光器。 该装置可以包括用于选择性地引导来自光源的光通过第一滤光器组件以产生第一频率范围的第一光束的机构,用于以第一成像模式照射舞台上的物体或通过第二滤光器组件 产生第二频率范围的第二光束,用于在第二成像模式下照射舞台上的物体,使得透镜和照相机系统捕获来自被第一或第二光束照射的物体的光,以产生第一 响应于第一光束的图像和与第一图像不同的第二图像。 可以包括x射线源和磷光体板以提供附加的成像模式。
    • 6. 发明授权
    • Lens adjustment assembly for electronic digital imaging apparatus
    • 用于电子数字成像设备的镜头调整组件
    • US6075549A
    • 2000-06-13
    • US418732
    • 1995-04-07
    • Mark E. Bridges
    • Mark E. Bridges
    • G03G15/04B41J2/455G02B7/02H04N1/04H04N1/113B41J2/47G01D15/34G02B26/00G02B27/00
    • B41J2/45B41J19/20G02B7/023
    • An electronic digital imaging apparatus includes an intensity-modulated light source for emitting a light beam along an optical path, an adjustment block to which the light source is fixed and which is movable along the optical path to move the light source along the optical path, and means for scanning the light beam along a recording surface. The adjustment block has two opposed ends and a central region; one of the opposed ends being fixed relative to the optical path, the other of the opposed ends being adjustable in the general direction of the optical path, and the central region carries the light source; whereby adjustment of the other of the opposed ends in the general direction of the optical path by a given distance is effective to move the light source along the optical path by a fraction of the given distance. Projection optics are detachably integral with the light source in the optical path for focusing the light beam at the recording surface. The projection optics being detachable from the light source without effecting the position of the light source along the optical path so as to not disturb the focus of the imaging apparatus upon re-attachment of the projection optics to the light source.
    • 电子数字成像装置包括用于沿光路发射光束的强度调制光源,固定有光源的调节块,其可沿光路移动以沿光路移动光源, 以及用于沿记录表面扫描光束的装置。 调节块具有两个相对的端部和中心区域; 相对端中的一个相对于光路固定,另一个相对端在光路的大致方向上是可调节的,中心区域承载光源; 由此将光路的大致方向上的另一个相对端的另一个调整给定距离是有效的,以使光源沿着光路移动给定距离的一部分。 投射光学元件与用于将光束聚焦在记录表面上的光路中的光源可分离地整合。 投影光学元件可以从光源可拆卸而不影响光源沿着光路的位置,以便在将投影光学器件重新附接到光源时不会影响成像设备的焦点。
    • 7. 发明授权
    • Printer with support shoe and media metering therein
    • 带有支撑鞋和介质计量的打印机
    • US5751334A
    • 1998-05-12
    • US371346
    • 1995-01-11
    • Mark E. Bridges
    • Mark E. Bridges
    • B41J15/04B65H20/02B65H23/192B65H23/26G03B27/58G03B41/00H04N1/00H04N1/08B41J2/435G01D15/24G11B7/00H01S1/131
    • H04N1/00588B65H20/02B65H23/26G03B27/588H04N1/0057H04N1/00591H04N1/00602H04N1/0061H04N1/00618H04N1/00679H04N1/08H04N1/0821H04N1/0856H04N1/0873H04N1/0886H04N2201/0404
    • An apparatus for accurately guiding a web of light-sensitive recording media into a cylindrical support shoe of a printer includes a metering roller at the inlet side of a stationary support shoe around which a received media web is wrapped. At least one media guide belt is mounted about a set of pulleys to guide media toward a nip between a pressure roller and the metering roller through which the media is driven into the stationary support shoe. The metering roller is mounted to rotate about a predetermined axis, and the pressure roller has one end held in a frame and is spring loaded into the frame and the metering roller. The other end of the pressure roller is also spring loaded into the metering roller and into an adjustment plate which is pivotal about the axis of the metering roller, whereby the pressure roller can be steered so that the axis of the metering roller and the axis of rotation of the pressure roller are made parallel, and so that the nip between the metering roller and the pressure roller can be adjusted to lie in a plane defined by the axis of the metering roller and the axis of rotation of the pressure roller to cause media to run uniformly and predictably when metering into and out of the cylindrical support shoe.
    • 用于将感光记录介质的网格精确地引导到打印机的圆柱形支撑鞋中的装置包括在固定支撑靴的入口侧的计量辊,所述接收的介质纤维网围绕所述计量辊被包裹。 至少一个介质导向带安装在一组滑轮周围,以将介质引导到压力辊与计量辊之间的辊隙,介质被驱动到定影辊中。 计量辊安装成围绕预定轴线旋转,并且压力辊的一端保持在框架中并且弹簧加载到框架和计量辊中。 压力辊的另一端还弹簧加载到计量辊中并进入调节板,该调节板围绕计量辊的轴线枢转,由此压力辊可以被转向,使得计量辊的轴线和轴线 使加压辊的旋转平行,从而能够调节计量辊和压力辊之间的辊隙以位于由计量辊的轴线和压力辊的旋转轴线所限定的平面中,以使介质 当计量进出圆柱形支撑鞋时,可以均匀和可预测地运行。