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1. 发明授权

US08270689B2 Apparatus for caries detection 有权
标题翻译：龋齿检测装置
公开(公告)号：US08270689B2
公开(公告)日：2012-09-18
申请号：US11530987
申请日：2006-09-12
申请人： Rongguang Liang , Victor C. Wong , Michael A. Marcus , Mark E. Bridges , Paul O. McLaughlin , Peter D. Burns , David L. Patton
发明人： Rongguang Liang , Victor C. Wong , Michael A. Marcus , Mark E. Bridges , Paul O. McLaughlin , Peter D. Burns , David L. Patton
IPC分类号： G06K9/00
CPC分类号： A61B5/0088 , A61B1/043 , A61B1/0607 , A61B1/0638 , A61B1/0646 , A61B1/0684 , A61B1/24 , A61B5/0035 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/4547 , A61B5/742 , A61B5/7425 , A61C1/088 , G01B9/02091 , G01B11/2441 , G01J3/02 , G01J3/0213 , G01J3/0224 , G01J3/0272 , G01J3/10 , G01J3/4406 , G01J3/508 , G01N21/4795 , G01N21/6445 , G01N21/6456 , G01N21/6486 , G01N2021/1787
摘要： An apparatus for obtaining an image of a tooth having at least one light source providing incident light having a first spectral range for obtaining a reflectance image (122) from the tooth and a second spectral range for exciting a fluorescence image (120) from the tooth. A polarizing beamsplitter (18) in the path of the incident light from both sources directs light having a first polarization state toward the tooth and directs light from the tooth having a second polarization state along a return path toward a sensor (68), wherein the second polarization state is orthogonal to the first polarization state. A first lens (22) in the return path directs image-bearing light from the tooth toward the sensor (68), and obtains image data from the portion of the light having the second polarization state. A long-pass filter (15) in the return path attenuates light in the second spectral range.
摘要翻译：一种用于获得具有至少一个光源的齿的图像的装置，所述至少一个光源提供具有第一光谱范围的入射光，以从所述牙齿获得反射图像（122）和用于从所述牙齿激发荧光图像（120）的第二光谱范围。来自两个源的入射光的路径中的偏振分束器（18）将具有第一偏振态的光朝向齿引导，并将来自具有第二偏振态的齿沿着返回路径引导到传感器（68），其中，第二偏振态与第一偏振态正交。返回路径中的第一透镜（22）将来自齿的图像承载光朝向传感器（68）引导，并从具有第二偏振状态的光的部分获得图像数据。返回路径中的长通滤波器（15）衰减第二光谱范围内的光。

2. 发明申请

US20080090198A1 Apparatus for caries detection 有权
标题翻译：龋齿检测装置
公开(公告)号：US20080090198A1
公开(公告)日：2008-04-17
申请号：US11549208
申请日：2006-10-13
申请人： Rongguang Liang , Victor C. Wong , Mark E. Bridges , Michael A. Marcus , David L. Patton , Peter D. Burns , Paul O. McLaughlin
发明人： Rongguang Liang , Victor C. Wong , Mark E. Bridges , Michael A. Marcus , David L. Patton , Peter D. Burns , Paul O. McLaughlin
IPC分类号： A61C1/00 , A61C5/00
CPC分类号： G01J3/51 , A61B1/00186 , A61B1/043 , A61B1/0615 , A61B1/0623 , A61B1/0638 , A61B1/247 , A61B5/0066 , A61B5/0088 , G01B11/285 , G01J3/02 , G01J3/0213 , G01J3/0224 , G01J3/36 , G01J3/4406 , G01J3/50 , G01J3/501 , G01J3/508 , G01J2003/468 , G01N21/6456
摘要： An apparatus for imaging a tooth having a light source with a first spectral range and a second spectral range. A polarizing beamsplitter (18) light having a first polarization state toward the tooth and directs light from the tooth having a second polarization state along a return path toward a sensor (68), wherein the first and second polarization states are orthogonal. A first lens (22) in the return path directs image-bearing light from the tooth, through the polarizing beamsplitter (18), toward the sensor (68), and obtains image data from the redirected portion of the light having the second polarization state. A long-pass filter (15) in the return path attenuates light in the second spectral range. Control logic enables the sensor to obtain either the reflectance image or the fluorescence image.
摘要翻译：一种用于对具有第一光谱范围和第二光谱范围的光源成像牙齿的装置。一种偏振分束器（18），其具有朝向齿的第一偏振态，并且沿着返回路径将来自具有第二偏振状态的齿导向传感器（68），其中第一和第二偏振态是正交的。返回路径中的第一透镜（22）将来自齿的图像承载光通过偏振分束器（18）朝向传感器（68）引导，并从具有第二偏振状态的光的重定向部分获得图像数据。返回路径中的长通滤波器（15）衰减第二光谱范围内的光。控制逻辑使传感器能够获得反射图像或荧光图像。

3. 发明授权

US06740474B2 Technique for making deep microstructures in photoresist 失效
标题翻译：在光致抗蚀剂中制备深度微结构的技术
公开(公告)号：US06740474B2
公开(公告)日：2004-05-25
申请号：US09993033
申请日：2001-11-06
申请人： John Border , Paul O. Mclaughlin
发明人： John Border , Paul O. Mclaughlin
IPC分类号： G03F700
CPC分类号： G03F7/0005 , G03F7/0037 , G03F7/2053
摘要： A method is disclosed for making deep microstructures in photoresist. The method utilizes a pool of photoresist on top of a transparent substrate and the laser is located below the substrate. Structures are created in the photoresist by transmitting the laser light through the substrate up into the photoresist. Since the photoresist does not have to be spin coated onto the substrate, very thick layers of photoresist can be used while the thickness uniformity is determined by the substrate surface. Alternately, a contoured substrate can be used while producing uniform structures.
摘要翻译：公开了一种在光致抗蚀剂中制造深度微结构的方法。该方法在透明衬底的顶部上使用光致抗蚀剂池，激光位于衬底下方。通过将激光通过衬底传输到光致抗蚀剂中，在光致抗蚀剂中产生结构。由于不需要将光致抗蚀剂旋转涂覆到基底上，所以可以使用非常厚的光致抗蚀剂层，而厚度均匀性由衬底表面确定。或者，可以使用轮廓基材，同时产生均匀的结构。

4. 发明授权

US07460248B2 Tissue imaging system 有权
标题翻译：组织成像系统
公开(公告)号：US07460248B2
公开(公告)日：2008-12-02
申请号：US11383254
申请日：2006-05-15
申请人： Andrew F. Kurtz , Joseph R. Bietry , Paul O. McLaughlin
发明人： Andrew F. Kurtz , Joseph R. Bietry , Paul O. McLaughlin
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： A61B5/0059 , A61B5/0066 , A61B5/412 , A61B5/445 , G01N21/21 , G01N21/23 , G01N21/4795 , G01N21/6458 , G01N21/6486
摘要： A tissue imaging system (200) for examining the medical condition of tissue (290) has an illumination optical system (205), which comprises a light source (220), having one or more light emitters, beam shaping optics, and polarizing optics. An optical beamsplitter (260) directs illumination light to an imaging sub-system, containing a spatial light modulator array (300). An objective lens (325) images illumination light from the spatial light modulator array to the tissue. An optical detection system (210) images the spatial light modulator to an optical detector array. A controller (360) drives the spatial light modulator to provide time variable arrangements of on-state pixels. The objective lens operates in a nominally telecentric manner relative to both the spatial light modulator and the tissue. The polarizing optics are independently and iteratively rotated to define variable polarization states relative to the tissue. The modulator pixels optically function like pinholes relative to the illumination light and the image light.
摘要翻译：用于检查组织（290）的医学状况的组织成像系统（200）具有照明光学系统（205），其包括具有一个或多个光发射器，光束整形光学器件和偏振光学器件的光源（220）。光分束器（260）将照明光引导到包含空间光调制器阵列（300）的成像子系统。物镜（325）将来自空间光调制器阵列的照明光图像转印到组织。光学检测系统（210）将空间光调制器成像到光学检测器阵列。控制器（360）驱动空间光调制器以提供导通状态像素的时间可变布置。物镜相对于空间光调制器和组织以标称远心方式工作。偏振光学器件被独立地并且迭代地旋转以限定相对于组织的可变极化状态。调制器像素相对于照明光和图像光光学地起着像针孔的作用。

5. 发明申请

US20080063998A1 APPARATUS FOR CARIES DETECTION 有权
标题翻译：检测器具
公开(公告)号：US20080063998A1
公开(公告)日：2008-03-13
申请号：US11530987
申请日：2006-09-12
申请人： Rongguang Liang , Victor C. Wong , Michael A. Marcus , Mark E. Bridges , Paul O, McLaughlin , Peter D. Burns , David L. Patton
发明人： Rongguang Liang , Victor C. Wong , Michael A. Marcus , Mark E. Bridges , Paul O, McLaughlin , Peter D. Burns , David L. Patton
IPC分类号： A61C3/00 , A61C5/00
CPC分类号： A61B5/0088 , A61B1/043 , A61B1/0607 , A61B1/0638 , A61B1/0646 , A61B1/0684 , A61B1/24 , A61B5/0035 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/4547 , A61B5/742 , A61B5/7425 , A61C1/088 , G01B9/02091 , G01B11/2441 , G01J3/02 , G01J3/0213 , G01J3/0224 , G01J3/0272 , G01J3/10 , G01J3/4406 , G01J3/508 , G01N21/4795 , G01N21/6445 , G01N21/6456 , G01N21/6486 , G01N2021/1787
摘要： An apparatus for obtaining an image of a tooth having at least one light source providing incident light having a first spectral range for obtaining a reflectance image (122) from the tooth and a second spectral range for exciting a fluorescence image (120) from the tooth. A polarizing beamsplitter (18) in the path of the incident light from both sources directs light having a first polarization state toward the tooth and directs light from the tooth having a second polarization state along a return path toward a sensor (68), wherein the second polarization state is orthogonal to the first polarization state. A first lens (22) in the return path directs image-bearing light from the tooth toward the sensor (68), and obtains image data from the portion of the light having the second polarization state. A long-pass filter (15) in the return path attenuates light in the second spectral range.
摘要翻译：一种用于获得具有至少一个光源的齿的图像的装置，所述至少一个光源提供具有第一光谱范围的入射光，以从所述牙齿获得反射图像（122）和用于从所述牙齿激发荧光图像（120）的第二光谱范围。来自两个源的入射光的路径中的偏振分束器（18）将具有第一偏振态的光朝向齿引导，并将来自具有第二偏振态的齿沿着返回路径引导到传感器（68），其中，第二偏振态与第一偏振态正交。返回路径中的第一透镜（22）将来自齿的图像承载光朝向传感器（68）引导，并从具有第二偏振状态的光的部分获得图像数据。返回路径中的长通滤波器（15）衰减第二光谱范围内的光。

6. 发明授权

US06385997B1 Method for forming a tool for molding microlens arrays 失效
标题翻译：用于形成用于模塑微透镜阵列的工具的方法
公开(公告)号：US06385997B1
公开(公告)日：2002-05-14
申请号：US09570609
申请日：2000-05-12
申请人： Jayson J. Nelson , Eugene G. Hill , Paul O. McLaughlin , John C. Pulver , Michael K. Budinski
发明人： Jayson J. Nelson , Eugene G. Hill , Paul O. McLaughlin , John C. Pulver , Michael K. Budinski
IPC分类号： C03B2326
CPC分类号： C03B11/084 , C03B11/082 , C03B2215/05 , C03B2215/414 , C03B2215/50 , Y02P40/57
摘要： A method for fabricating a mold tool for molding optical elements is taught which comprises heating a mold tool blank made from a vitreous material to a temperature above the glass transition temperature of the vitreous material; generating an axial viscosity gradient in the mold tool blank; pressing a punch into an optical quality mold surface of the mold tool blank, the punch including a pressing surface with a predetermined geometry for forming an optical feature; cooling the mold tool blank to a temperature below the glass transition temperature of the material; and removing the punch from the mold tool blank thereby creating the optical feature in the optical quality mold surface. The axial viscosity gradient is achieved by creating an axial thermal gradient. Multiple optical features can be formed in the mold surface of the blank using a single punch such that the pressing, cooling and removing steps are repeated with the punch or the blank being translated to a different position between the last removing step and the next pressing step. In such manner, a high temperature glass mold tool can be formed which can be used to mold glass optical elements either individually or in arrays.
摘要翻译：一种用于制造用于模制光学元件的模具的方法，包括将由玻璃质材料制成的模具坯料加热到高于玻璃质材料的玻璃化转变温度的温度; 在模具坯料中产生轴向粘度梯度; 将冲头压入模具坯料的光学质量模具表面中，冲头包括具有用于形成光学特征的预定几何形状的按压表面; 将模具坯料冷却到低于材料的玻璃化转变温度的温度; 并从模具坯料上移除冲头，从而在光学质量模具表面中形成光学特征。通过产生轴向热梯度来实现轴向粘度梯度。可以使用单个冲头在坯料的模具表面中形成多个光学特征，使得当冲头或坯料被转换到最后的去除步骤和下一个压制步骤之间的不同位置时，重复挤压，冷却和移除步骤。以这种方式，可以形成高温玻璃模具，其可以单独地或阵列地用于模制玻璃光学元件。

7. 发明授权

US06324010B1 Optical assembly and a method for manufacturing lens systems 有权
标题翻译：光学组件和制造透镜系统的方法
公开(公告)号：US06324010B1
公开(公告)日：2001-11-27
申请号：US09516094
申请日：2000-02-29
申请人： John P. Bowen , Michael K. Budinski , Paul D. Ludington , Paul O. Mclaughlin
发明人： John P. Bowen , Michael K. Budinski , Paul D. Ludington , Paul O. Mclaughlin
IPC分类号： G02B2710
CPC分类号： G02B3/0062 , B29D11/00278 , B29D11/0073 , G02B3/0075 , G02B13/0085
摘要： According to one aspect of the present invention, a method of making a lens assembly with a plurality of lens arrays having a plurality of lenslets and at least one spacer having a plurality of holes, includes the steps of (i) arranging at least two lens arrays and the spacer, such that the spacer is located between the two lens arrays and the lenslets of one of the two lens arrays overlay the lenslets of another one of the two lens arrays and, the holes of the spaces are located between the corresponding lenslets of the two lens arrays; (ii) fixedly attaching the lens arrays and the spacer to one another to form an array assembly; and (iii) dividing the array assembly to create a plurality of individual lens systems. According to another aspect of the present invention, the optical assembly includes at least two lens arrays and at least one spacer with a plurality of holes. The spacer is located between the two lens arrays and is fixedly attached to the two lens arrays. The spacer has a thickness of 0.05 to 0.5 mm. The lens arrays have a plurality of lenslets of no more than 1 mm in diameter. It is preferred that the lens arrays have a largest dimension of at least 5 mm.
摘要翻译：根据本发明的一个方面，制造具有多个具有多个小透镜的多个透镜阵列和至少一个具有多个孔的间隔物的透镜组件的方法包括以下步骤：（i）将至少两个透镜阵列和间隔物，使得间隔物位于两个透镜阵列之间，并且两个透镜阵列之一的小透镜覆盖两个透镜阵列中的另一个透镜阵列的小透镜，并且空间的孔位于相应的小透镜的两个透镜阵列; （ii）将透镜阵列和间隔件固定地彼此连接以形成阵列组件; 和（iii）分割阵列组件以产生多个单独的透镜系统。根据本发明的另一方面，光学组件包括至少两个透镜阵列和至少一个具有多个孔的间隔物。间隔件位于两个透镜阵列之间，并且固定地附接到两个透镜阵列。间隔物的厚度为0.05〜0.5mm。透镜阵列具有多个直径不大于1mm的小透镜。优选的是，透镜阵列具有至少5mm的最大尺寸。

8. 发明授权

US08866894B2 Method for real-time visualization of caries condition 有权
标题翻译：龋齿状况的实时可视化方法
公开(公告)号：US08866894B2
公开(公告)日：2014-10-21
申请号：US12017400
申请日：2008-01-22
申请人： Victor C. Wong , Gary M. Spinelli , Peter D. Burns , Paul O. McLaughlin , Jean Marc Inglese
发明人： Victor C. Wong , Gary M. Spinelli , Peter D. Burns , Paul O. McLaughlin , Jean Marc Inglese
IPC分类号： G06K9/00 , A61B5/00 , G06T7/00
CPC分类号： G06T7/0012 , A61B5/0088 , G06T7/11 , G06T7/187 , G06T2207/10016 , G06T2207/30036
摘要： A method for displaying live video of a tooth identifies a tooth tissue region in a viewable image frame obtained from a video stream and processes pixel data within the tooth tissue region to identify a suspected caries site. Intensity values for pixels that correspond to the suspected caries site are modified and a highlighted viewable image frame is formed as a combination of the modified intensity values corresponding to the suspected caries site and other pixel values in the viewable image frame. The highlighted viewable image frame is displayed in video form.
摘要翻译：用于显示牙齿的实时视频的方法识别从视频流获得的可视图像帧中的牙齿组织区域，并且处理牙齿组织区域内的像素数据以识别怀疑的龋齿部位。修改对应于可疑龋齿部位的像素的强度值，并且将可突出显示的可视图像帧形成为可视图像帧中对应于可疑龋齿部位和其他像素值的修改强度值的组合。突出显示的可视图像帧以视频形式显示。

9. 发明授权

US08077949B2 Apparatus for caries detection 有权
标题翻译：龋齿检测装置
公开(公告)号：US08077949B2
公开(公告)日：2011-12-13
申请号：US12723733
申请日：2010-03-15
申请人： Rongguang Liang , Victor C. Wong , Mark E. Bridges , Michael A. Marcus , David L. Patton , Peter D. Burns , Paul O. McLaughlin
发明人： Rongguang Liang , Victor C. Wong , Mark E. Bridges , Michael A. Marcus , David L. Patton , Peter D. Burns , Paul O. McLaughlin
IPC分类号： G06K9/00
CPC分类号： G01J3/51 , A61B1/00186 , A61B1/043 , A61B1/0615 , A61B1/0623 , A61B1/0638 , A61B1/247 , A61B5/0066 , A61B5/0088 , G01B11/285 , G01J3/02 , G01J3/0213 , G01J3/0224 , G01J3/36 , G01J3/4406 , G01J3/50 , G01J3/501 , G01J3/508 , G01J2003/468 , G01N21/6456
摘要： An apparatus for imaging a tooth having a light source with a first spectral range and a second spectral range. A polarizing beamsplitter (18) light having a first polarization state toward the tooth and directs light from the tooth having a second polarization state along a return path toward a sensor (68), wherein the first and second polarization states are orthogonal. A first lens (22) in the return path directs image-bearing light from the tooth, through the polarizing beamsplitter (18), toward the sensor (68), and obtains image data from the redirected portion of the light having the second polarization state. A long-pass filter (15) in the return path attenuates light in the second spectral range. Control logic enables the sensor to obtain either the reflectance image or the fluorescence image.
摘要翻译：一种用于对具有第一光谱范围和第二光谱范围的光源成像牙齿的装置。一种偏振分束器（18），其具有朝向齿的第一偏振态，并且沿着返回路径将来自具有第二偏振状态的齿导向传感器（68），其中第一和第二偏振态是正交的。返回路径中的第一透镜（22）将来自齿的图像承载光通过偏振分束器（18）朝向传感器（68）引导，并从具有第二偏振状态的光的重定向部分获得图像数据。返回路径中的长通滤波器（15）衰减第二光谱范围内的光。控制逻辑使传感器能够获得反射图像或荧光图像。

10. 发明申请

US20100165089A1 APPARATUS FOR CARIES DETECTION 有权
标题翻译：检测器具
公开(公告)号：US20100165089A1
公开(公告)日：2010-07-01
申请号：US12723733
申请日：2010-03-15
申请人： Rongguang Liang , Victor C. Wong , Mark E. Bridges , Michael A. Marcus , David L. Patton , Peter D. Burns , Paul O. McLaughlin
发明人： Rongguang Liang , Victor C. Wong , Mark E. Bridges , Michael A. Marcus , David L. Patton , Peter D. Burns , Paul O. McLaughlin
IPC分类号： H04N7/18
CPC分类号： G01J3/51 , A61B1/00186 , A61B1/043 , A61B1/0615 , A61B1/0623 , A61B1/0638 , A61B1/247 , A61B5/0066 , A61B5/0088 , G01B11/285 , G01J3/02 , G01J3/0213 , G01J3/0224 , G01J3/36 , G01J3/4406 , G01J3/50 , G01J3/501 , G01J3/508 , G01J2003/468 , G01N21/6456
摘要： An apparatus for imaging a tooth having a light source with a first spectral range and a second spectral range. A polarizing beamsplitter (18) light having a first polarization state toward the tooth and directs light from the tooth having a second polarization state along a return path toward a sensor (68), wherein the first and second polarization states are orthogonal. A first lens (22) in the return path directs image-bearing light from the tooth, through the polarizing beamsplitter (18), toward the sensor (68), and obtains image data from the redirected portion of the light having the second polarization state. A long-pass filter (15) in the return path attenuates light in the second spectral range. Control logic enables the sensor to obtain either the reflectance image or the fluorescence image.
摘要翻译：一种用于对具有第一光谱范围和第二光谱范围的光源成像牙齿的装置。一种偏振分束器（18），其具有朝向齿的第一偏振态，并且沿着返回路径将来自具有第二偏振状态的齿导向传感器（68），其中第一和第二偏振态是正交的。返回路径中的第一透镜（22）将来自齿的图像承载光通过偏振分束器（18）朝向传感器（68）引导，并从具有第二偏振状态的光的重定向部分获得图像数据。返回路径中的长通滤波器（15）衰减第二光谱范围内的光。控制逻辑使传感器能够获得反射图像或荧光图像。

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