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    • 5. 发明申请
    • INDIVIDUAL PUMP CALIBRATION FOR ULTRAFILTRATION CONTROL IN A DIALYSIS APPARATUS
    • 用于DIALYSIS设备中超声波控制的个体泵校准
    • WO2015007595A1
    • 2015-01-22
    • PCT/EP2014/064743
    • 2014-07-09
    • GAMBRO LUNDIA AB
    • JANSSON, Olof
    • A61M1/16A61M1/34F04B43/00
    • A61M1/1615A61M1/16A61M1/165A61M1/34A61M1/3403A61M1/3413A61M2205/12A61M2205/3334A61M2205/3351A61M2205/3355A61M2205/3389A61M2205/3396A61M2205/50A61M2205/52A61M2205/70A61M2205/702F04B49/065F04B51/00
    • A control unit (30) is arranged to control a dialysis fluid distribution system (12) comprising first and second volumetric pumps (PI, P2) arranged upstream and downstream of a dialyzer (13). The control unit (30) is operable in a calibration mode, to establish a bypass flow path that bypasses the dialyzer (13) and extends from the first pump (P1) to the second pump (P2) in fluid communication with a calibration chamber (26) and to operate the pumps (P1, P2) at different combinations of speeds that cause first and second changes in fluid level in the chamber (26). The first and second changes correspond to first and second known volumes in the chamber (26). The control unit (30) measures, by a level detector (28) in the chamber (26), first and second time periods for the first and second changes, and computes the stroke volumes of the pumps (P1, P2) as a function of the speeds of the pumps (PI, P2), the first and second time periods, and the first and second known volumes. By computing the stroke volumes, the control unit (30) is operable to achieve an accurate ultrafiltration (UF) rate in the dialyzer (13) by controlling the relative speeds of the pumps (P1, P2).
    • 控制单元(30)被布置成控制透析液体分配系统(12),其包括布置在透析器(13)的上游和下游的第一和第二体积泵(PI,P2)。 控制单元(30)可在校准模式下操作,以建立绕过透析器(13)并从第一泵(P1)延伸到第二泵(P2)的旁路流动路径,其与校准室流体连通 并且以不同的速度组合来操作泵(P1,P2),这些组合导致腔室(26)中的液位的第一和第二变化。 第一和第二改变对应于腔室(26)中的第一和第二已知体积。 控制单元(30)通过室(26)中的液位检测器(28)测量用于第一和第二变化的第一和第二时间段,并且将泵(P1,P2)的行程体积计算为函数 的泵(PI,P2)的速度,第一和第二时间段以及第一和第二已知体积。 通过计算行程体积,控制单元(30)可操作以通过控制泵(P1,P2)的相对速度来实现透析器(13)中的精确超滤(UF)速率。
    • 6. 发明申请
    • DISPOSABLES FOR BLOOD TREATMENT, AND METHODS OF OPERATING THE SAME
    • 用于血液治疗的药物及其操作方法
    • WO2012175435A1
    • 2012-12-27
    • PCT/EP2012/061551
    • 2012-06-18
    • GAMBRO LUNDIA ABJANSSON, OlofHOLMER, MattiasNILSSON, EddieJÖNSSON, Lennart
    • JANSSON, OlofHOLMER, MattiasNILSSON, EddieJÖNSSON, Lennart
    • A61M1/30A61M1/36
    • A61M1/367A61M1/30A61M1/302A61M1/303A61M1/306A61M1/3621A61M2205/125A61M2205/128Y10T137/0318Y10T137/85986Y10T137/86035
    • A disposable for use in blood treatment comprises a blood treatment unit (8) and a pump arrangement (11) operable to pump blood through the blood treatment unit (8). The pump arrangement (11) comprises two membrane pumps (6, 7) connected in parallel on one side of the blood treatment unit (8). The disposable is operable in a single-needle mode, in which the pump arrangement (11) is operable to generate a pulsatile flow of blood through the blood treatment unit (8), and in a double-needle mode, in which the pump arrangement (11) is operable to generate an essentially continuous flow of blood through the blood treatment unit (8). The pump arrangement (11) is configured for connection to a supply system (1) of treatment fluid for the blood treatment unit (8) such that alternating flows of treatment fluid generated by the supply system (1) and supplied to the first and second membrane pumps (6, 7) causes the pump arrangement (11) to generate the desired flows of blood in the single-needle and double- needle modes. The treatment fluid may be used as motive fluid for displacing the blood in the membrane pumps (6, 7) and/or as control fluid for controlling opening and/or closing of upstream and downstream commutation valves (34, 35) in the membrane pumps (6, 7).
    • 用于血液处理的一次性用品包括血液处理单元(8)和可操作以将血液泵送通过血液处理单元(8)的泵装置(11)。 泵装置(11)包括在血液处理单元(8)的一侧上并联连接的两个膜泵(6,7)。 一次性可以单针模式操作,其中泵装置(11)可操作以通过血液处理单元(8)产生脉动血液流,并且在双针模式中,泵装置 (11)可操作以通过血液处理单元(8)产生基本上连续的血液流。 泵装置(11)构造成用于连接到用于血液处理单元(8)的处理流体的供应系统(1),使得由供应系统(1)产生并供应到第一和第二 膜泵(6,7)使泵装置(11)以单针和双针模式产生所需的血液流。 处理流体可以用作移动膜泵(6,7)中的血液的运动流体和/或用作控制膜泵中上游和下游换向阀(34,35)的打开和/或关闭的控制流体 (6,7)。