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1. 发明申请

WO2012004103A1 AN AMBULATORY ULTRAFILTRATION DEVICE, RELATED METHODS AND A COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：一种超声波超声装置，相关方法和计算机程序产品
公开(公告)号：WO2012004103A1
公开(公告)日：2012-01-12
申请号：PCT/EP2011/060019
申请日：2011-06-16
申请人： GAMBRO LUNDIA AB , JÖNSSON, Lennart , STERNBY, Jan , WIESLANDER, Anders
发明人： JÖNSSON, Lennart , STERNBY, Jan , WIESLANDER, Anders
IPC分类号： A61M1/30
CPC分类号： A61M1/30 , A61M1/302 , A61M1/303 , A61M1/3427 , A61M1/3604 , A61M1/365 , A61M1/3672 , A61M2209/088
摘要： An ultrafiltration device is designed to be used for ambulatory SCUF or other types of continuous or intermittent ultrafiltration, typically while being worn or otherwise carried by the subject (S) that is being treated. The ambulatory ultrafiltration device comprises a blood filter (4) that has a blood side (6) for fluid communication with the vascular system of the subject (S), an ultrafiltrate side (7), and a semipermeable membrane (8) disposed between the blood side (6) and the ultrafiltrate side (7). The ambulatory ultrafiltration also comprises a buffer vessel (3) in fluid communication with the blood side (6) of the blood filter (4), and a blood pump (9). The blood pump (9) is controlled to alternate between a withdrawal phase and a return phase. In the withdrawal phase, blood is withdrawn on a blood path from the subject (S) via the blood filter (4) to the buffer vessel (3). In the return phase, blood is returned from the buffer vessel (3) to the subject (S) on the blood path. The blood filter (4) is arranged to remove ultrafiltrate from the blood during at least one of the withdrawal and return phases. The use of a single blood path for withdrawal of blood and return of treated blood makes the device suitable for ambulatory ultrafiltration.
摘要翻译：超滤装置设计用于移动SCUF或其他类型的连续或间歇超滤，通常在正在治疗的受试者（S）穿着或以其他方式携带时。动态超滤装置包括血液过滤器（4），其具有用于与受试者（S）的血管系统流体连通的血液侧（6），超滤液侧（7）和设置在所述受试者的血液系统之间的半透膜（8）血液侧（6）和超滤液侧（7）。动态超滤还包括与血液过滤器（4）的血液侧（6）流体连通的缓冲容器（3）和血液泵（9）。血泵（9）被控制为在抽出阶段和返回阶段之间交替。在取出阶段，血液在血液路径上从被检体（S）经由血液过滤器（4）抽出到缓冲容器（3）。在返回阶段，将血液从缓冲容器（3）返回到血液路径上的受试者（S）。血液过滤器（4）布置成在至少一个抽出和返回阶段期间从血液中除去超滤液。使用单个血液路径来取出血液并返回处理过的血液，使得该装置适合于动态超滤。

2. 发明申请

WO2011161056A2 DIALYSIS PRECURSOR COMPOSITION 审中-公开
标题翻译： DIALYSIS前身组成
公开(公告)号：WO2011161056A2
公开(公告)日：2011-12-29
申请号：PCT/EP2011/060233
申请日：2011-06-20
申请人： GAMBRO LUNDIA AB , CARLSSON, Ola , JÖNSSON, Lennart , LINDEN, Torbjörn , WIESLANDER, Anders
发明人： CARLSSON, Ola , JÖNSSON, Lennart , LINDEN, Torbjörn , WIESLANDER, Anders
IPC分类号： A61K9/00
CPC分类号： A61K33/14 , A61K9/0029 , A61K9/0095 , A61K31/185 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/7004 , A61K33/00 , A61K33/06 , A61K33/10 , A61M1/1666 , A61M1/287 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one magnesium salt, and optionally potassium salt, and calcium salt. According to the invention said glucose and said at least one magnesium salt, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译：本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水，含钠浓缩物和含碳酸氢盐的浓缩液混合成即用型透析溶液。所述透析酸前体组合物由包含葡萄糖，至少一种干酸和至少一种镁盐，以及任选的钾盐和钙盐的粉末组分组成。根据本发明，所述葡萄糖和所述至少一种镁盐以所述透析酸前体组合物中的无水组分存在。

3. 发明申请

WO2010043595A1 BLOOD TREATMENT APPARATUS AND METHOD 审中-公开
标题翻译：血液处理装置和方法
公开(公告)号：WO2010043595A1
公开(公告)日：2010-04-22
申请号：PCT/EP2009/063290
申请日：2009-10-12
申请人： GAMBRO LUNDIA AB , HOLMER, Mattias , JÖNSSON, Lennart , WALLENBORG, Anders , HANSSON, Per
发明人： HOLMER, Mattias , JÖNSSON, Lennart , WALLENBORG, Anders , HANSSON, Per
IPC分类号： A61M1/10 , A61M1/16 , A61M1/30 , A61M1/34
CPC分类号： A61M1/16 , A61M1/1601 , A61M2205/50
摘要： A blood treatment apparatus, comprising a blood treatment unit (D) configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid, a pair of fluid pumps ( PF1, PF2; PF3, PF4) configured to pass blood treatment fluid through the blood treatment unit (D), a pair of blood pumps ( PB1, PB2) configured to extract untreated blood from a blood source (BS), pass extracted blood through the blood treatment unit (D) and deliver treated blood to a target vessel (BT), each blood pump comprising a pump chamber and a flexible member ( FM1; FM2) separating the pumping chamber into a first blood accumulating container (B1; B2) and a second working fluid accumulating container (F1; F2) where the flexible member is configured to vary a volume relationship between the first and the second accumulation containers. Further the apparatus comprises a control unit (P) and a measuring means configured to emit a feedback signal indicative of the amount of working fluid received into, or discharged from at least one of the second accumulation containers (F1; F2) whereby the pumped mass or volume of working fluid is determined by the control unit (P) at an arbitrary position of the flexible member (FM1, FM2).
摘要翻译：一种血液处理装置，包括：血液处理单元（D），被配置为接收未经处理的血液和新鲜血液处理液，并且发射处理过的血液和使用的血液处理液;一对流体泵（PF1，PF2; PF3，PF4）通过血液处理单元（D）通过血液处理液，构成为从血液源（BS）中提取未经处理的血液的一对血液泵（PB1，PB2），通过血液处理单元（D）将提取的血液通过，每个血液泵包括泵室和将泵送室分成第一血液积聚容器（B1; B2）和第二工作流体积聚容器（F1; B2）的柔性构件（FM1; FM2） F2），其中柔性构件构造成改变第一和第二蓄积容器之间的体积关系。此外，该装置包括控制单元（P）和测量装置，该测量装置被配置为发射指示接收到或从第二积聚容器（F1; F2）中的至少一个排出的工作流体的量的反馈信号，由此泵送的质量或者在柔性构件（FM1，FM2）的任意位置处由控制单元（P）确定工作流体的体积。

4. 发明申请

WO2009127624A3 BLOOD TREATMENT APPARATUS 审中-公开
公开(公告)号：WO2009127624A3
公开(公告)日：2009-10-22
申请号：PCT/EP2009/054406
申请日：2009-04-14
申请人： GAMBRO LUNDIA AB , JÖNSSON, Lennart , JANSSON, Olof , HOLMER, Mattias , STERNBY, Jan , NILSSON, Anders , HANSSON, Per
发明人： JÖNSSON, Lennart , JANSSON, Olof , HOLMER, Mattias , STERNBY, Jan , NILSSON, Anders , HANSSON, Per
IPC分类号： A61M1/10 , A61M1/16 , A61M1/30 , A61M1/34
摘要： A proposed blood treatment apparatus includes : a blood treatment unit (8), a pair of fluid pumps (14, 15) and a pair of blood pumps (1a, 1b). The blood treatment unit (8) is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps (14, 15) are configured to pass blood treatment fluid through the blood treatment unit (8). The blood pumps (1a, 1b) are configured to extract untreated blood from a blood source (S), pass extracted blood through the blood treatment unit (8) and deliver treated blood to a target vessel (T). Additionally, the fluid pumps (14, 15) are configured to control the operation of the blood pumps (1a, 1b) via the blood treatment fluid. Moreover, a flow control means (16a) is configured to control a trans- membrane flow between the blood side (8B) and the a fluid side (8F) of the blood treatment unit (8). Hence, for instance ultrafiltration can be adjusted to a desired level in a very straightforward manner.

5. 发明申请

WO2002086177A1 STEEL ARTICLE 审中-公开
标题翻译：钢制品
公开(公告)号：WO2002086177A1
公开(公告)日：2002-10-31
申请号：PCT/SE2002/000714
申请日：2002-04-11
申请人： UDDEHOLM TOOLING AKTIEBOLAG , SANDBERG, Odd , JÖNSSON, Lennart
发明人： SANDBERG, Odd , JÖNSSON, Lennart
IPC分类号： C22C38/24
CPC分类号： C22C38/22 , C21D1/18 , C21D1/25 , C22C38/24 , C22C38/36 , C22C38/60
摘要： The invention concerns an article of a steel which is characterized in that it consists of an alloy which contains in weight-%: 1.2-2.0 C, 0.1-1.5 Si, 0.1-2.0 Mn, max. 0.2 N, max. 0.25 S, 4-8 Cr, 0.5-3.5 (Mo+W/2), 5-8 V, max. 1.0 Nb, balance essentially only iron and unavoidable impurities, and that the steel has a micro-structure obtainable by a manufacturing of the steel which comprises spray forming of an ingot, the micro-structure of which contains 8-15 vol-% carbides of essentially only MC-type where M substantially consists of vanadium, of which carbides at least 80 vol-% have a substantially rounded shape and a size in the longest extension of the carbides amounting to 1-20 µm.
摘要翻译：本发明涉及钢的制品，其特征在于它由以重量％计含有：1.2-2.0C，0.1-1.5Si，0.1-2.0Mn，最大值的合金组成。 0.2 N，最大 0.25 S，4-8 Cr，0.5-3.5（Mo + W / 2），5-8 V，最大 1.0 Nb，基本上仅平衡铁和不可避免的杂质，并且钢具有通过钢的制造可获得的微观结构，该微结构包括喷雾形成锭，其微结构含有8-15体积％的碳化物基本上只有MC型，其中M基本上由钒组成，其中至少80体积％的碳化物具有基本圆形的形状，碳化物最长延伸的尺寸为1-20微米。

6. 发明申请

WO1983001829A1 HEATING SYSTEM 审中-公开
标题翻译：加热系统
公开(公告)号：WO1983001829A1
公开(公告)日：1983-05-26
申请号：PCT/SE1982000380
申请日：1982-11-11
申请人： AB SKANEVERKEN , LINDE, Olle , JÖNSSON, Lennart
发明人： AB SKANEVERKEN
IPC分类号： F24D03/10
CPC分类号： F24D11/002
摘要： A heating system for buildings comprises a storage tank (1) for accommodating a heating medium, preferably water, a heating means (14) connected to said storage tank, a plurality of radiators (2), a pipeline system (3, 4, 5) extending between said storage tank and radiators for conveying the heating medium, at least some of said radiators and/or a part of said pipeline system lying at a higher level than said storage tank (1), and a valve means (13, 13') disposed in said pipeline system (3) and adapted to vent said pipeline system and said radiators when these are filled with the heating medium. The pipeline system is closed and, during operation of said heating system, does not communicate with the surroundings, whereby said storage tank is not affected by any static excess pressure deriving from that part of the heating medium which is contained in those radiators and that part of said pipeline system which are above said storage tank.
摘要翻译：一种用于建筑物的加热系统包括用于容纳加热介质（优选为水）的储罐（1），连接到所述储罐的加热装置（14），多个散热器（2），管道系统（3,4,5 ）在所述储罐和散热器之间延伸，用于输送加热介质，至少一些所述散热器和/或所述管道系统的一部分处于比所述储罐（1）更高的水平;以及阀装置（13,13 '）设置在所述管道系统（3）中并且适于当所述管道系统和所述散热器在充满所述加热介质时排出。管道系统关闭，并且在所述加热系统的操作期间不与周围环境连通，由此所述储罐不受来自所述散热器中包含的那部分加热介质的任何静态过量压力的影响，并且该部分的所述管道系统。

7. 发明申请

WO2012175435A1 DISPOSABLES FOR BLOOD TREATMENT, AND METHODS OF OPERATING THE SAME 审中-公开
标题翻译：用于血液治疗的药物及其操作方法
公开(公告)号：WO2012175435A1
公开(公告)日：2012-12-27
申请号：PCT/EP2012/061551
申请日：2012-06-18
申请人： GAMBRO LUNDIA AB , JANSSON, Olof , HOLMER, Mattias , NILSSON, Eddie , JÖNSSON, Lennart
发明人： JANSSON, Olof , HOLMER, Mattias , NILSSON, Eddie , JÖNSSON, Lennart
IPC分类号： A61M1/30 , A61M1/36
CPC分类号： A61M1/367 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/306 , A61M1/3621 , A61M2205/125 , A61M2205/128 , Y10T137/0318 , Y10T137/85986 , Y10T137/86035
摘要： A disposable for use in blood treatment comprises a blood treatment unit (8) and a pump arrangement (11) operable to pump blood through the blood treatment unit (8). The pump arrangement (11) comprises two membrane pumps (6, 7) connected in parallel on one side of the blood treatment unit (8). The disposable is operable in a single-needle mode, in which the pump arrangement (11) is operable to generate a pulsatile flow of blood through the blood treatment unit (8), and in a double-needle mode, in which the pump arrangement (11) is operable to generate an essentially continuous flow of blood through the blood treatment unit (8). The pump arrangement (11) is configured for connection to a supply system (1) of treatment fluid for the blood treatment unit (8) such that alternating flows of treatment fluid generated by the supply system (1) and supplied to the first and second membrane pumps (6, 7) causes the pump arrangement (11) to generate the desired flows of blood in the single-needle and double- needle modes. The treatment fluid may be used as motive fluid for displacing the blood in the membrane pumps (6, 7) and/or as control fluid for controlling opening and/or closing of upstream and downstream commutation valves (34, 35) in the membrane pumps (6, 7).
摘要翻译：用于血液处理的一次性用品包括血液处理单元（8）和可操作以将血液泵送通过血液处理单元（8）的泵装置（11）。泵装置（11）包括在血液处理单元（8）的一侧上并联连接的两个膜泵（6,7）。一次性可以单针模式操作，其中泵装置（11）可操作以通过血液处理单元（8）产生脉动血液流，并且在双针模式中，泵装置（11）可操作以通过血液处理单元（8）产生基本上连续的血液流。泵装置（11）构造成用于连接到用于血液处理单元（8）的处理流体的供应系统（1），使得由供应系统（1）产生并供应到第一和第二膜泵（6,7）使泵装置（11）以单针和双针模式产生所需的血液流。处理流体可以用作移动膜泵（6,7）中的血液的运动流体和/或用作控制膜泵中上游和下游换向阀（34,35）的打开和/或关闭的控制流体（6,7）。

8. 发明申请

WO2012035040A1 BLOOD TREATMENT APPARATUS WITH FLOW DIVIDER FOR LIMITING AN ELECTRICAL CURRENT 审中-公开
标题翻译：用于限制电流的流量分配器的血液处理装置
公开(公告)号：WO2012035040A1
公开(公告)日：2012-03-22
申请号：PCT/EP2011/065894
申请日：2011-09-14
申请人： GAMBRO LUNDIA AB , HANSSON, Per , HERTZ, Thomas , HOLMER, Mattias , JÖNSSON, Lennart , NILSSON, Anders , WALLENBORG, Anders , ANDERSSON, Johan
发明人： HANSSON, Per , HERTZ, Thomas , HOLMER, Mattias , JÖNSSON, Lennart , NILSSON, Anders , WALLENBORG, Anders , ANDERSSON, Johan
IPC分类号： A61M1/14 , A61M1/36
CPC分类号： A61M1/367 , A61M1/14 , A61M1/1601 , A61M1/3621 , A61M2205/3317 , A61M2205/3334 , A61M2205/50 , Y10T29/49002
摘要： A blood treatment apparatus (2) comprising: a blood treatment unit (10); a blood line (20) configured to extract blood from a blood source (21), pass the blood through the blood treatment unit (10) and deliver treated blood to a target vessel (22); and a fluid line (30) configured pass treatment fluid through the blood treatment unit (10) and deliver used treatment fluid to a fluid sink (32). A flow divider (40) is arranged in the fluid line (30) separates treatment fluid into to a first fluid section (51) and a second fluid section (53), thereby electrically isolating the fluid sections (51, 53) such that electrical current flowing in the fluid line (30) between the fluid sections (51, 53) is limited. Related manufacturing and verification methods are also described.
摘要翻译：一种血液处理装置（2），包括：血液处理单元（10）; 构成为从血液源（21）取出血液的血液线（20），使血液通过血液处理单元（10），将处理后的血液输送到目标血管（22）。并且流体管线（30）构造成通过处理液通过血液处理单元（10）并将使用的处理流体输送到流体槽（32）。在流体管线（30）中布置有分流器（40），其将处理流体分离成第一流体部分（51）和第二流体部分（53），从而将流体部分（51,53）电隔离，使得电气在流体管线（30）内流动的流体部分（51,53）之间的电流受到限制。还描述了相关的制造和验证方法。

9. 发明申请

WO2011161064A1 PREPARATION OF MEDICAL SOLUTIONS FROM POWDERY MATERIAL 审中-公开
标题翻译：从粉末材料制备医疗解决方案
公开(公告)号：WO2011161064A1
公开(公告)日：2011-12-29
申请号：PCT/EP2011/060255
申请日：2011-06-20
申请人： GAMBRO LUNDIA AB , JANSSON, Olof , JÖNSSON, Lennart , LINDEN, Torbjörn , STERNBY, Jan , TRYGGVASON, Ragnar , WIESLANDER, Anders
发明人： JANSSON, Olof , JÖNSSON, Lennart , LINDEN, Torbjörn , STERNBY, Jan , TRYGGVASON, Ragnar , WIESLANDER, Anders
IPC分类号： A61J1/20 , A61M1/16
CPC分类号： A61J1/20 , A61J1/2093 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/167 , A61M1/287 , B65D31/14 , B65D81/18 , B65D81/20 , B65D81/2007 , B65D81/2023 , B65D81/2046
摘要： A package has a transport/storage state for storing powdery material which is to be mixed with a solvent to form a medical solution, e.g. for use in dialysis treatment. The package comprises a compartment (6) which is at least partially defined by two opposing wall portions, and a connector (10). In the transport/storage state, the compartment contains the powdery material in the form of at least two distinct sets (2A-2D) of powdery material of different compositions, where the opposing wall portions are brought into engagement with the powdery material so as to immobilize the sets of powdery material (2A-2D). When used for preparation of the medical solution, a fluid is selectively admitted into the package via the connector (10) so as to expand the compartment (6) and enable mixing of the sets (2A-2D) of powdery material with the solvent in the compartment (6).
摘要翻译：包装具有用于储存待与溶剂混合以形成医用溶液的粉末状材料的运输/储存状态，用于透析治疗。该包装件包括至少部分地由两个相对的壁部分限定的隔室（6）和连接器（10）。在运输/储存状态下，隔室含有至少两种不同组成的粉末材料组（2A-2D）形式的粉状材料，其中相对的壁部分与粉末材料接合，以便固定一组粉状材料（2A-2D）。当用于制备医用溶液时，通过连接器（10）将流体选择性地进入包装中，以便使隔室（6）膨胀，并使粉末材料组（2A-2D）与溶剂的组合隔室（6）。

10. 发明申请

WO2011161055A1 DIALYSIS PRECURSOR COMPOSITION 审中-公开
标题翻译： DIALYSIS前身组成
公开(公告)号：WO2011161055A1
公开(公告)日：2011-12-29
申请号：PCT/EP2011/060231
申请日：2011-06-20
申请人： GAMBRO LUNDIA AB , CARLSSON, Ola , LINDEN, Torbjörn , JÖNSSON, Lennart , WIESLANDER, Anders
发明人： CARLSSON, Ola , LINDEN, Torbjörn , JÖNSSON, Lennart , WIESLANDER, Anders
IPC分类号： A61K31/7004 , A61K33/00 , A61K33/06 , A61K33/14 , A61K9/00
CPC分类号： A61K33/14 , A61K9/0029 , A61K9/0095 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61K31/7004 , A61K33/00 , A61K33/06 , A61M1/287 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consist of powder components comprising sodium chloride, at least one dry acid and at least one magnesium salt, and optionally potassium salt, calcium salt, and glucose. According to the invention said at least one magnesium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译：本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水和含碳酸氢盐的浓缩液混合成即用型透析溶液。所述透析酸前体组合物由包含氯化钠，至少一种干酸和至少一种镁盐，以及任选的钾盐，钙盐和葡萄糖的粉末组分组成。根据本发明，所述至少一种镁盐和所述任选的葡萄糖以所述透析酸前体组合物中的无水组分存在。

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