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1. 发明授权

US09421359B2 Probe for implantable electro-stimulation device 有权
标题翻译：探针用于植入式电刺激装置
公开(公告)号：US09421359B2
公开(公告)日：2016-08-23
申请号：US13120758
申请日：2009-10-07
申请人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
发明人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/05 , H05K9/00 , A61N1/08
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0531 , A61N1/0551 , A61N1/056 , A61N1/086 , H05K9/002
摘要： The invention relates to a probe for an implantable electro-stimulation device. The probe (20) has a distal end (12) and a proximal end (13), and moreover comprises: one or more electrodes (11) a shield (21) of conducting material covering a major part of the probe, said shield extending from the vicinity of at least one of the one or more electrodes (11) towards the proximal end (13) or towards the distal end (12) of the probe (20); and a layer (22a, 22b) of insulating material covering part of the shield (21) in the vicinity of the at least one of the one or more electrodes. The shield protects wires (14), extending from electrodes to the proximal end of the probe, from undesired interference of external RF fields. The exposed part of the shield not covered by the layer of insulating material serves as a return electrode for the electrostimulation signal path.
摘要翻译：本发明涉及可植入电刺激装置的探针。探针（20）具有远端（12）和近端（13），并且还包括：一个或多个电极（11）覆盖探针的主要部分的导电材料的屏蔽件（21），所述屏蔽件延伸从所述一个或多个电极（11）中的至少一个朝向所述近端（13）或所述探针（20）的远端（12）的附近; 以及覆盖所述一个或多个电极中的至少一个电极附近的所述屏蔽体（21）的一部分的绝缘材料层（22a，22b）。屏蔽保护从电极延伸到探针近端的电线（14）免受外部RF场的不期望的干扰。未被绝缘材料层覆盖的屏蔽件的暴露部分用作电刺激信号路径的返回电极。

2. 发明申请

US20110184495A1 PROBE FOR IMPLANTABLE ELECTRO-STIMULATION DEVICE 有权
标题翻译：可植入电刺激装置的探针
公开(公告)号：US20110184495A1
公开(公告)日：2011-07-28
申请号：US13120758
申请日：2009-10-07
申请人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
发明人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/36
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0531 , A61N1/0551 , A61N1/056 , A61N1/086 , H05K9/002
摘要： The invention relates to a probe for an implantable electro-stimulation device. The probe (20) has a distal end (12) and a proximal end (13), and moreover comprises: one or more electrodes (11) a shield (21) of conducting material covering a major part of the probe, said shield extending from the vicinity of at least one of the one or more electrodes (11) towards the proximal end (13) or towards the distal end (12) of the probe (20); and a layer (22a, 22b) of insulating material covering part of the shield (21) in the vicinity of the at least one of the one or more electrodes. The shield protects wires (14), extending from electrodes to the proximal end of the probe, from undesired interference of external RF fields. The exposed part of the shield not covered by the layer of insulating material serves as a return electrode for the electrostimulation signal path.
摘要翻译：本发明涉及可植入电刺激装置的探针。探针（20）具有远端（12）和近端（13），并且还包括：一个或多个电极（11）覆盖探针的主要部分的导电材料的屏蔽件（21），所述屏蔽件延伸从所述一个或多个电极（11）中的至少一个朝向所述近端（13）或所述探针（20）的远端（12）的附近; 以及覆盖所述一个或多个电极中的至少一个电极附近的所述屏蔽体（21）的一部分的绝缘材料层（22a，22b）。屏蔽保护从电极延伸到探针近端的电线（14）免受外部RF场的不期望的干扰。未被绝缘材料层覆盖的屏蔽件的暴露部分用作电刺激信号路径的返回电极。

3. 发明授权

US09669208B2 Spiraled wires in a deep-brain stimulator probe 有权
公开(公告)号：US09669208B2
公开(公告)日：2017-06-06
申请号：US13128257
申请日：2009-11-09
申请人： Dirk Willem Harberts , Ke Wang , Franciscus Paulus Maria Budzelaar , Hubert Cecile Francois Martens
发明人： Dirk Willem Harberts , Ke Wang , Franciscus Paulus Maria Budzelaar , Hubert Cecile Francois Martens
IPC分类号： A61N1/00 , A61N1/05 , H01B7/04 , A61N1/37 , A61N1/08
CPC分类号： A61N1/0534 , A61N1/05 , A61N1/086 , A61N1/3718 , H01B7/048
摘要： The present invention regards a probe for deep brain stimulation (DBS), with high overall impedance, but low overall resistance. This is achieved since the probe comprises a structure comprising at least two interconnected spirals, wherein said two spirals have different direction of rotation. A system for deep brain stimulation comprising the probe, a power source and an electrode is also disclosed.

4. 发明授权

US08688230B2 System comprising a box for implanting in a body part 有权
标题翻译：系统包括用于植入身体部位的盒子
公开(公告)号：US08688230B2
公开(公告)日：2014-04-01
申请号：US13265408
申请日：2010-04-21
申请人： Michel Gerardus Pardoel , Michel Marcel Jose Decre , Hubert Cécile François Martens , Franciscus Paulus Maria Budzelaar , Jozef Elisabeth Franciscus Gootzen , Jeroen Jacob Arnold Tol
发明人： Michel Gerardus Pardoel , Michel Marcel Jose Decre , Hubert Cécile François Martens , Franciscus Paulus Maria Budzelaar , Jozef Elisabeth Franciscus Gootzen , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/08
CPC分类号： A61N1/375 , A61N1/0529 , A61N1/0539 , A61N1/37229
摘要： A system (102) comprising a box (104) for implanting in a mammal body part (106), which box is provided with a first electrical contact (110, 121, 114, 116, 118, 120), and a module (108) for accommodating in the box, which module is provided with a second electrical contact (122, 124, 126) for cooperation with said first electrical contact. The first electrical contact and the second electrical contact are mutually movable, at least in a stationary accommodation of the module in the box, between a contact position in which said first and second electrical contacts are electrically connected, and a non-contact position in which said first and second electrical contacts are separated from each other.
摘要翻译：一种系统（102），包括用于植入哺乳动物体部分（106）中的盒（104），所述盒设置有第一电触头（110,121,114,116,118,120）和模块（108 ），用于容纳在盒中，该模块设置有用于与所述第一电触点配合的第二电触点（122,124,126）。所述第一电触点和所述第二电接触件至少在所述模块在所述模块的静态容纳部中，在所述第一和第二电触点电连接的触点位置和非接触位置之间，所述第一和第二电触点彼此分离。

5. 发明申请

US20130030500A1 Method and System for Determining Settings for Deep Brain Stimulation 有权
标题翻译：用于确定深脑刺激设置的方法和系统
公开(公告)号：US20130030500A1
公开(公告)日：2013-01-31
申请号：US13581484
申请日：2011-02-25
申请人： Emil Toader , Hubert Cécile François Martens , Michel Marcel Jose Decre , Franciscus Paulus Maria Budzelaar , Pieter Gerrit Blanken , David James Anderson
发明人： Emil Toader , Hubert Cécile François Martens , Michel Marcel Jose Decre , Franciscus Paulus Maria Budzelaar , Pieter Gerrit Blanken , David James Anderson
IPC分类号： A61N1/36
CPC分类号： A61N1/36139 , A61N1/00 , A61N1/0534 , A61N1/36185
摘要： A method and a control system (20) are provided for determining a relation between stimulation settings for a brain stimulation probe (10) and a corresponding V-field. The brain stimulation probe (10) comprises multiple stimulation electrodes (11). The V-field is an electrical field in brain tissue surrounding the stimulation electrodes (11). The method comprises sequentially applying a test current to n stimulation electrodes (11), n being a number between 2 and the number of stimulation electrodes (11) of the brain stimulation probe (10), for each test current at one of the n stimulation electrodes (11), measuring a resulting excitation voltage at m stimulation electrodes, m being a number between 2 and the number of stimulation electrodes (11) of the brain stimulation probe (10), from the stimulation settings and the measured excitation voltages, deriving an (m*{acute over (η)}) coupling matrix, an element (q, p) in the coupling matrix reflecting an amount of electrical impedance between two of the stimulation electrodes (11), and using the coupling matrix for determining the relation between the stimulation settings and the corresponding V-field.
摘要翻译：提供一种方法和控制系统（20），用于确定脑刺激探针（10）的刺激设置与相应的V场之间的关系。脑刺激探针（10）包括多个刺激电极（11）。 V场是围绕刺激电极（11）的脑组织中的电场。所述方法包括对n个刺激电极（11）依次施加测试电流，n是在刺激探针（10）的刺激电极（11）的数量之间的数量，对于在n个刺激之一的每个测试电流电极（11），根据刺激设置和所测量的激发电压，测量m个刺激电极处的所得激励电压，m为2个与脑刺激探针（10）的刺激电极（11）的数量之间的数字，导出耦合矩阵中的元素（q，p），反映两个刺激电极（11）之间的电阻抗的量，并且使用用于确定的耦合矩阵刺激设置与相应V字段之间的关系。

6. 发明申请

US20110184492A1 SYSTEM AND METHOD FOR COMMUNICATING INFORMATION BETWEEN IMPLANTABLE DEVICES 有权
标题翻译：用于在可移植设备之间传递信息的系统和方法
公开(公告)号：US20110184492A1
公开(公告)日：2011-07-28
申请号：US13054857
申请日：2009-07-22
申请人： Hubert Cécile François Martens , Franciscus Paulus Maria Budzelaar , Jeroen Jacob Arnold Tol
发明人： Hubert Cécile François Martens , Franciscus Paulus Maria Budzelaar , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/36
CPC分类号： A61N1/37288 , A61N1/362 , A61N1/37252
摘要： A system for communicating information between at least two medical devices implanted within the body of a subject using volume conduction of electrical signals as a means of communication and wherein one of the implanted medical devices is configured to provide electrical stimulation to the tissue is disclosed. The system comprises a first implant device having at least two transmit electrodes configured to transmit electrical stimulation pulses, wherein one of the electrodes may be a common return electrode, an encoding means configured to employ a channel as a transmitter transmission medium for stimulation pulses and encoding the information into the stimulation pulses, a second implant device having at least two receive electrodes configured to receive the transmitted stimulation pulses with encoded information, and a decoding means configured to decode the information encoded into the stimulation pulses. The disclosed system provides reliable and efficient communication between implantable receiver devices.
摘要翻译：公开了一种系统，用于在作为通信手段的电信号的体积传导之间在植入物体内的至少两个医疗设备之间传送信息，并且其中植入的医疗设备中的一个被配置为向组织提供电刺激。所述系统包括具有至少两个发射电极的第一注入装置，所述至少两个发射电极被配置为传输电刺激脉冲，其中所述电极中的一个可以是公共返回电极，编码装置被配置为使用通道作为用于刺激脉冲的发射器传输介质和编码将信息输入到刺激脉冲中，具有至少两个接收电极的第二植入装置，所述接收电极被配置为用编码信息接收所发送的刺激脉冲;以及解码装置，被配置为对编码为刺激脉冲的信息进行解码。所公开的系统在可植入接收器设备之间提供可靠和有效的通信。

7. 发明授权

US09662170B2 Sensing apparatus for sensing an object 有权
公开(公告)号：US09662170B2
公开(公告)日：2017-05-30
申请号：US13885474
申请日：2011-11-03
申请人： Franciscus Paulus Maria Budzelaar , Nenad Mihajlovic , Antonius Johannes Josephus Rademakers , Cornelius Antonius Nicholaas Maria Van Der Vleuten
发明人： Franciscus Paulus Maria Budzelaar , Nenad Mihajlovic , Antonius Johannes Josephus Rademakers , Cornelius Antonius Nicholaas Maria Van Der Vleuten
IPC分类号： A61B18/14 , A61B8/12 , A61B8/08 , A61B18/00 , A61B5/00 , A61B8/00
CPC分类号： A61B18/1492 , A61B5/7217 , A61B8/0883 , A61B8/12 , A61B8/445 , A61B8/4494 , A61B8/486 , A61B2018/00357 , A61B2018/00577 , A61B2018/00589 , A61B2562/182
摘要： The invention relates to a sensing apparatus for sensing an object. The sensing apparatus comprises an ultrasound unit (11) for ultrasonically sensing the object (4), an electrical energy application unit (9) for applying electrical energy to the object (4), and an ultrasound unit shielding element (16) for electrically shielding the ultrasound unit (11), wherein the ultrasound unit shielding element (16) is electrically connected to the electrical energy application unit (9). Since the ultrasound unit shielding element electrically shields the ultrasound unit, the ultrasound sensing of the object is less influenced by a capacitive coupling of the application of electrical energy, in particular, of an RF signal which may be used for applying the electrical energy, into the ultrasound sensing. A further reduction of this influence is achieved by electrically connecting the ultrasound unit shielding element to the electrical energy application unit.

8. 发明授权

US09278225B2 Apparatus with internal power transfer 有权
标题翻译：具有内部电力传输的装置
公开(公告)号：US09278225B2
公开(公告)日：2016-03-08
申请号：US13383601
申请日：2010-06-30
申请人： Jeroen Jacob Arnold Tol , Franciscus Paulus Maria Budzelaar
发明人： Jeroen Jacob Arnold Tol , Franciscus Paulus Maria Budzelaar
IPC分类号： H02M3/335 , A61N1/378 , A61N1/08 , A61N1/05 , H02M3/28 , H02J7/00 , H02J1/00 , H02M7/48
CPC分类号： A61N1/378 , A61N1/08 , H02J7/0065 , H02J2001/002 , H02M7/48
摘要： An electronic apparatus with a DC power source and power-consuming electronic circuits and a method of transferring power between these components include converting the DC voltage of the power source into an AC voltage which is then transferred via a connector to the electronic circuits.
摘要翻译：具有直流电源和功耗电子电路的电子设备以及在这些组件之间传送电力的方法包括将电源的直流电压转换为交流电压，然后将交流电压通过连接器传送到电子电路。

9. 发明申请

US20100060623A1 DRIVE METHOD FOR AN ELECTROPHORETIC CELL AND AN ELECTROPHORETIC DEVICE 有权
标题翻译：用于电泳细胞和电泳装置的驱动方法
公开(公告)号：US20100060623A1
公开(公告)日：2010-03-11
申请号：US12516814
申请日：2007-11-27
申请人： Martinus Hermanus Wilhelmus Maria Van Delden , Sander Jurgen Roosendaal , Patrick John Baesjou , Alwin Rogier Martijn Verschueren , Franciscus Paulus Maria Budzelaar
发明人： Martinus Hermanus Wilhelmus Maria Van Delden , Sander Jurgen Roosendaal , Patrick John Baesjou , Alwin Rogier Martijn Verschueren , Franciscus Paulus Maria Budzelaar
IPC分类号： G09G3/34 , G06F3/038
CPC分类号： G09G3/3446 , G02F2001/1676 , G09G3/2011 , G09G3/2014 , G09G3/2022 , G09G2300/0426 , G09G2300/0434 , G09G2300/0465 , G09G2300/06 , G09G2310/0245 , G09G2310/04 , G09G2320/0252 , G09G2320/0261 , G09G2380/02
摘要： The present invention relates to a drive method for an electrophoretic cell and a device adapted to implement the method. The cell comprises a first storage electrode (24), a second storage electrode (22), a first target area electrode (28), a second target area electrode (30), a first type of particle (32) and a second type of particles (33), said second type of particles being of opposite polarity to the first type of particles. An area (31) extending between the target area electrodes (28, 30) is a target area. The method comprises a reset phase (110), wherein said first and second type of particle are reset to determined reset positions, a first write phase (120), wherein the first type of particles are moved to and/or from the storage electrodes and change in amount in said target area (31), a second write phase (140) similar to the first write phase but for the second type of particles, and a spread phase (150) so that the particles in said target area (31) distribute and mix. The method allows for short distance movements and two particle type in the same cell can be written comparatively fast.
摘要翻译：本发明涉及电泳池的驱动方法和适于实现该方法的装置。电池包括第一存储电极（24），第二存储电极（22），第一目标区域电极（28），第二目标区域电极（30），第一类型的粒子（32）和第二类型颗粒（33），所述第二类型的颗粒与第一类型的颗粒具有相反的极性。在目标区域电极（28,30）之间延伸的区域（31）是目标区域。该方法包括复位阶段（110），其中所述第一和第二类型的粒子被复位到确定的复位位置，第一写入阶段（120），其中第一类型的粒子被移动到和/或从存储电极和/ 所述目标区域（31）中的量的变化，类似于第一写入阶段但是对于第二类型的粒子的第二写入阶段（140）和扩展阶段（150），使得所述目标区域（31）中的粒子分发和混合。该方法允许短距离移动，并且相同单元格中的两个粒子类型可以写得比较快。

10. 发明授权

US07271756B2 Non-linear distribution of voltage steps in flash-type A/D converters 有权
标题翻译：闪光型A / D转换器的电压阶跃非线性分布
公开(公告)号：US07271756B2
公开(公告)日：2007-09-18
申请号：US10537670
申请日：2003-11-28
申请人： Franciscus Paulus Maria Budzelaar
发明人： Franciscus Paulus Maria Budzelaar
IPC分类号： H03M1/12
CPC分类号： H03M1/188 , H03M1/1235 , H03M1/367
摘要： A method, apparatus, and system for converting an input voltage VIN to a digital output. A comparison of VIN with reference voltages in one or more flash-type analog-to-digital (A/D) converters generates the digital output representing VIN. If one A/D converter is used, the A/D converter is non-linear. If more than one A/D converter are used, the A/D converters are each linear.
摘要翻译：一种用于将输入电压VIN转换为数字输出的方法，装置和系统。在一个或多个闪存型模拟（A / D）转换器中，VIN与参考电压的比较产生表示VIN的数字输出。如果使用一个A / D转换器，则A / D转换器是非线性的。如果使用多个A / D转换器，则A / D转换器各自是线性的。

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