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1. 发明授权

US09421359B2 Probe for implantable electro-stimulation device 有权
标题翻译：探针用于植入式电刺激装置
公开(公告)号：US09421359B2
公开(公告)日：2016-08-23
申请号：US13120758
申请日：2009-10-07
申请人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
发明人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/05 , H05K9/00 , A61N1/08
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0531 , A61N1/0551 , A61N1/056 , A61N1/086 , H05K9/002
摘要： The invention relates to a probe for an implantable electro-stimulation device. The probe (20) has a distal end (12) and a proximal end (13), and moreover comprises: one or more electrodes (11) a shield (21) of conducting material covering a major part of the probe, said shield extending from the vicinity of at least one of the one or more electrodes (11) towards the proximal end (13) or towards the distal end (12) of the probe (20); and a layer (22a, 22b) of insulating material covering part of the shield (21) in the vicinity of the at least one of the one or more electrodes. The shield protects wires (14), extending from electrodes to the proximal end of the probe, from undesired interference of external RF fields. The exposed part of the shield not covered by the layer of insulating material serves as a return electrode for the electrostimulation signal path.
摘要翻译：本发明涉及可植入电刺激装置的探针。探针（20）具有远端（12）和近端（13），并且还包括：一个或多个电极（11）覆盖探针的主要部分的导电材料的屏蔽件（21），所述屏蔽件延伸从所述一个或多个电极（11）中的至少一个朝向所述近端（13）或所述探针（20）的远端（12）的附近; 以及覆盖所述一个或多个电极中的至少一个电极附近的所述屏蔽体（21）的一部分的绝缘材料层（22a，22b）。屏蔽保护从电极延伸到探针近端的电线（14）免受外部RF场的不期望的干扰。未被绝缘材料层覆盖的屏蔽件的暴露部分用作电刺激信号路径的返回电极。

2. 发明申请

US20110184495A1 PROBE FOR IMPLANTABLE ELECTRO-STIMULATION DEVICE 有权
标题翻译：可植入电刺激装置的探针
公开(公告)号：US20110184495A1
公开(公告)日：2011-07-28
申请号：US13120758
申请日：2009-10-07
申请人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
发明人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
IPC分类号： A61N1/36
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0531 , A61N1/0551 , A61N1/056 , A61N1/086 , H05K9/002
摘要： The invention relates to a probe for an implantable electro-stimulation device. The probe (20) has a distal end (12) and a proximal end (13), and moreover comprises: one or more electrodes (11) a shield (21) of conducting material covering a major part of the probe, said shield extending from the vicinity of at least one of the one or more electrodes (11) towards the proximal end (13) or towards the distal end (12) of the probe (20); and a layer (22a, 22b) of insulating material covering part of the shield (21) in the vicinity of the at least one of the one or more electrodes. The shield protects wires (14), extending from electrodes to the proximal end of the probe, from undesired interference of external RF fields. The exposed part of the shield not covered by the layer of insulating material serves as a return electrode for the electrostimulation signal path.
摘要翻译：本发明涉及可植入电刺激装置的探针。探针（20）具有远端（12）和近端（13），并且还包括：一个或多个电极（11）覆盖探针的主要部分的导电材料的屏蔽件（21），所述屏蔽件延伸从所述一个或多个电极（11）中的至少一个朝向所述近端（13）或所述探针（20）的远端（12）的附近; 以及覆盖所述一个或多个电极中的至少一个电极附近的所述屏蔽体（21）的一部分的绝缘材料层（22a，22b）。屏蔽保护从电极延伸到探针近端的电线（14）免受外部RF场的不期望的干扰。未被绝缘材料层覆盖的屏蔽件的暴露部分用作电刺激信号路径的返回电极。

3. 发明授权

US09669208B2 Spiraled wires in a deep-brain stimulator probe 有权
公开(公告)号：US09669208B2
公开(公告)日：2017-06-06
申请号：US13128257
申请日：2009-11-09
申请人： Dirk Willem Harberts , Ke Wang , Franciscus Paulus Maria Budzelaar , Hubert Cecile Francois Martens
发明人： Dirk Willem Harberts , Ke Wang , Franciscus Paulus Maria Budzelaar , Hubert Cecile Francois Martens
IPC分类号： A61N1/00 , A61N1/05 , H01B7/04 , A61N1/37 , A61N1/08
CPC分类号： A61N1/0534 , A61N1/05 , A61N1/086 , A61N1/3718 , H01B7/048
摘要： The present invention regards a probe for deep brain stimulation (DBS), with high overall impedance, but low overall resistance. This is achieved since the probe comprises a structure comprising at least two interconnected spirals, wherein said two spirals have different direction of rotation. A system for deep brain stimulation comprising the probe, a power source and an electrode is also disclosed.

4. 发明申请

US20110224765A1 SPIRALED WIRES IN A DEEP-BRAIN STIMULATOR PROBE 有权
标题翻译：螺旋激光探针中的螺旋线
公开(公告)号：US20110224765A1
公开(公告)日：2011-09-15
申请号：US13128257
申请日：2009-11-09
申请人： Dirk Willem Harberts , Ke Wang , Fraciscus Paulus Maria Budzelaar , Hubert Cecile Francois Martens
发明人： Dirk Willem Harberts , Ke Wang , Fraciscus Paulus Maria Budzelaar , Hubert Cecile Francois Martens
IPC分类号： A61N1/05
CPC分类号： A61N1/0534 , A61N1/05 , A61N1/086 , A61N1/3718 , H01B7/048
摘要： The present invention regards a probe for deep brain stimulation (DBS), with high overall impedance, but low overall resistance. This is achieved since the probe comprises a structure comprising at least two interconnected spirals, wherein said two spirals have different direction of rotation. A system for deep brain stimulation comprising the probe, a power source and an electrode is also disclosed.
摘要翻译：本发明涉及用于深部脑刺激（DBS）的探针，具有高的总体阻抗，但总体电阻较低。这是因为探针包括包括至少两个互连螺旋的结构，其中所述两个螺旋具有不同的旋转方向。还公开了一种包括探针，电源和电极的深脑刺激系统。

5. 发明申请

US20110190860A1 PROBE FOR AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：可植入医疗器械的探针
公开(公告)号：US20110190860A1
公开(公告)日：2011-08-04
申请号：US13120854
申请日：2009-10-08
申请人： Dirk Willem Harberts , Ke Wang , Michel Marcel Jose Decre
发明人： Dirk Willem Harberts , Ke Wang , Michel Marcel Jose Decre
IPC分类号： A61N1/00
CPC分类号： A61N1/0534 , A61B5/0476 , A61B5/6864 , A61B5/6865 , A61B90/11 , A61N1/0529 , A61N1/08 , A61N1/086
摘要： The invention relates to a probe (10) for an implantable medical device. The probe has a distal end (2) and a proximal end (3), and the probe (10) moreover comprises an electrode (1) at the distal end. The electrode is connected to a wire (5) extending from the electrode to the proximal end of the probe, where the resistivity of the wire is non-uniform along the length of the wire. The wire may have high resistivity at the distal end of the probe and low resistivity wires elsewhere. The high resistivity wires reduce the peak current density in the tissue of an implanted device, and thus prevents destructive heating and/or undesired stimulation of tissue during MRI examination. This highly contributes to MR safety which is a highly desired feature for these implantable electrical stimulation devices.
摘要翻译：本发明涉及一种用于可植入医疗装置的探针（10）。探针具有远端（2）和近端（3），并且探针（10）还包括位于远端的电极（1）。电极连接到从电极延伸到探针的近端的线（5），其中线的电阻率沿着线的长度是不均匀的。导线在探头的远端可能具有高电阻率，而其他地方的电阻率较低。高电阻率线降低植入装置的组织中的峰值电流密度，从而防止在MRI检查期间的组织的破坏性加热和/或不期望的刺激。这高度有助于MR安全性，这是这些可植入电刺激装置的高度期望的特征。

6. 发明授权

US08948843B2 Probe for an implantable medical device 有权
标题翻译：探针可植入医疗器械
公开(公告)号：US08948843B2
公开(公告)日：2015-02-03
申请号：US13120854
申请日：2009-10-08
申请人： Dirk Willem Harberts , Ke Wang , Michel Marcel Jose Decre
发明人： Dirk Willem Harberts , Ke Wang , Michel Marcel Jose Decre
IPC分类号： A61B5/055 , A61N1/08 , A61N1/05 , A61B5/00 , A61B5/0476 , A61B19/00
CPC分类号： A61N1/0534 , A61B5/0476 , A61B5/6864 , A61B5/6865 , A61B90/11 , A61N1/0529 , A61N1/08 , A61N1/086
摘要： The invention relates to a probe (10) for an implantable medical device. The probe has a distal end (2) and a proximal end (3), and the probe (10) moreover comprises an electrode (1) at the distal end. The electrode is connected to a wire (5) extending from the electrode to the proximal end of the probe, where the resistivity of the wire is non-uniform along the length of the wire. The wire may have high resistivity at the distal end of the probe and low resistivity wires elsewhere. The high resistivity wires reduce the peak current density in the tissue of an implanted device, and thus prevents destructive heating and/or undesired stimulation of tissue during MRI examination. This highly contributes to MR safety which is a highly desired feature for these implantable electrical stimulation devices.
摘要翻译：本发明涉及一种用于可植入医疗装置的探针（10）。探针具有远端（2）和近端（3），并且探针（10）还包括位于远端的电极（1）。电极连接到从电极延伸到探针的近端的线（5），其中线的电阻率沿着线的长度是不均匀的。导线在探头的远端可能具有高电阻率，而其他地方的电阻率较低。高电阻率线降低植入装置的组织中的峰值电流密度，从而防止在MRI检查期间的组织的破坏性加热和/或不期望的刺激。这高度有助于MR安全性，这是这些可植入电刺激装置的高度期望的特征。

7. 发明授权

US06548952B2 CRT having a deflection unit with anti-ringing characteristics 失效
公开(公告)号：US06548952B2
公开(公告)日：2003-04-15
申请号：US09966437
申请日：2001-09-28
申请人： Dirk Willem Harberts , Hendrik Dirk Van Den Berg
发明人： Dirk Willem Harberts , Hendrik Dirk Van Den Berg
IPC分类号： H01J2970
CPC分类号： H01J29/76
摘要： A cathode ray tube (1) having an improved deflection unit (11) is described. The deflection unit (11) comprises line and/or frame coils that comprise a composition of wires having a conductive coating and wires having a non-conductive coating. Such deflection units have a good anti-ringing performance, while the good adhesion characteristics of non-conducting coated wires are maintained.

8. 发明授权

US07504638B2 Digital flat X-ray detector 失效
标题翻译：数字平板X射线探测器
公开(公告)号：US07504638B2
公开(公告)日：2009-03-17
申请号：US11912327
申请日：2006-04-13
申请人： Lex Alving , Dirk Willem Harberts , Hans Stouten , Stephanus Berardus Worm
发明人： Lex Alving , Dirk Willem Harberts , Hans Stouten , Stephanus Berardus Worm
IPC分类号： G01T1/24
CPC分类号： G01T1/2928
摘要： In a flat X-ray detector, Electromagnetic Interference (EMI) is reduced by either opening a pickup loop between the common lines (28) and the reference plane (29) of the PCB, or by reducing the size of a pickup loop by providing a permanent connection (33) between the common supply line and the reference plane (29) in respect of each row of photoconductors (12).
摘要翻译：在平板X射线检测器中，通过在公共线路（28）和PCB的参考平面（29）之间打开拾音环路，或通过提供拾音器环路的尺寸来减小电磁干扰（EMI）相对于每排感光体（12），共用电源线和参考平面（29）之间的永久连接（33）。

9. 发明授权

US06888298B2 Cathode ray tube with convergence unit 失效
标题翻译：阴极射线管与会聚单元
公开(公告)号：US06888298B2
公开(公告)日：2005-05-03
申请号：US10056369
申请日：2002-01-17
申请人： Dirk Willem Harberts , Leopold Cyrille Maria Beirens , Antonius Henricus Van Tiel
发明人： Dirk Willem Harberts , Leopold Cyrille Maria Beirens , Antonius Henricus Van Tiel
IPC分类号： H01J29/54 , H01J29/76 , H04N9/28 , H01J29/51
CPC分类号： H01J29/76
摘要： The invention relates to a color display device comprising an electron gun (5) for generating three electron beams (6,7,8), and convergence means (14) for dynamically influencing the convergence of the electron beams. The convergence means (14) comprise coils (22) for generating a magnetic field. The coils (22) are provided with an electrically conducting layer.
摘要翻译：本发明涉及包括用于产生三个电子束（6,7,8）的电子枪（5）和用于动态地影响电子束会聚的会聚装置（14）的彩色显示装置。会聚装置（14）包括用于产生磁场的线圈（22）。线圈（22）设置有导电层。

10. 发明授权

US09205252B2 Medical device for electrical stimulation 有权
标题翻译：医疗器械用于电刺激
公开(公告)号：US09205252B2
公开(公告)日：2015-12-08
申请号：US13386677
申请日：2010-07-16
申请人： Dirk Willem Harberts , Rio Vetter
发明人： Dirk Willem Harberts , Rio Vetter
IPC分类号： A61N1/05 , A61N1/00 , A61N1/36 , A61N1/08
CPC分类号： A61N1/0534 , A61N1/00 , A61N1/086 , A61N1/36082
摘要： The present invention relates to a medical device (2) for electrical stimulation. The device comprising an implantable elongated lead system (20) having a distal end (21) and a proximal end (22), the lead system comprises one or more electrical conductors (23) for connection to one or more electrodes (24). The one or more electrical conductors are wound along a length axis (25) of the lead system with a plurality of windings, and wherein the density of windings is non-uniformly distributed along the length axis. In an embodiment, the medical device is in the form of a deep brain stimulation (DBS) device.
摘要翻译：本发明涉及一种用于电刺激的医疗装置（2）。所述装置包括具有远端（21）和近端（22）的可植入的细长引导系统（20），所述引导系统包括用于连接到一个或多个电极（24）的一个或多个电导体（23）。一个或多个电导体沿引线系统的长度轴线（25）缠绕有多个绕组，并且其中绕组的密度沿着长度轴不均匀分布。在一个实施例中，医疗装置是深部脑刺激（DBS）装置的形式。

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