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1. 发明申请

US20050192619A1 Vaso-occlusive coils with non-overlapping sections 失效
标题翻译：具有非重叠部分的血管闭塞线圈
公开(公告)号：US20050192619A1
公开(公告)日：2005-09-01
申请号：US10791092
申请日：2004-03-01
申请人： Clifford Teoh , Michael Wallace
发明人： Clifford Teoh , Michael Wallace
IPC分类号： A61B17/12 , A61M29/00
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12145 , A61B2017/00526
摘要： A vaso-occlusive implant has a primary helical-coil shape that defines a primary axis and a three-dimensional secondary shape. The secondary shape includes a substantially helical section and a second section having a plurality of non-overlapping loops or loop sections. Each loop defines a plane that is oriented at an angle from about 30-150 degrees relative to a plane defined by an immediately preceding or immediately succeeding loop along the primary axis. The coil sections or loops can be generally circular loops or other smooth shapes.
摘要翻译：血管闭塞植入体具有限定主轴线和三维二次形状的初级螺旋线圈形状。次级形状包括基本上螺旋的部分和具有多个非重叠环或环部分的第二部分。每个环限定了相对于由紧邻的前一个或紧随其后的环沿主轴定义的平面以大约30-150度的角度定向的平面。线圈段或环可以是大体圆环或其它平滑形状。

2. 发明申请

US20100106162A1 FLEXIBLE EMBOLIC DEVICE DELIVERY SYSTEM 审中-公开
标题翻译：灵活的装置输送系统
公开(公告)号：US20100106162A1
公开(公告)日：2010-04-29
申请号：US12652565
申请日：2010-01-05
申请人： Kevin M. Jaeger , Stephen C. Porter , Clifford Teoh , Michael Wallace , Maria Pizarro
发明人： Kevin M. Jaeger , Stephen C. Porter , Clifford Teoh , Michael Wallace , Maria Pizarro
IPC分类号： A61F11/00 , A61F2/01
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/00862 , A61B2017/00867 , A61B2017/1205 , A61B2017/12063
摘要： The present invention provides an embolic assembly delivery apparatus having superior flexibility characteristics at its distal end, that is, at the point of attachment of the embolic assembly to the delivery apparatus. It also provides a method of using the apparatus to deliver an embolic assembly to a target site in a patient's body.
摘要翻译：本发明提供一种栓塞组件输送装置，其在其远端具有优异的柔性特性，即在栓塞组件与输送装置的连接点处。它还提供了一种使用该装置将栓塞组件递送到患者身体中的目标部位的方法。

3. 发明授权

US07651513B2 Flexible embolic device delivery system 有权
标题翻译：柔性栓塞装置输送系统
公开(公告)号：US07651513B2
公开(公告)日：2010-01-26
申请号：US10407295
申请日：2003-04-03
申请人： Clifford Teoh , Stephen C. Porter , Kevin M. Jaeger , Michael Wallace
发明人： Clifford Teoh , Stephen C. Porter , Kevin M. Jaeger , Michael Wallace
IPC分类号： A61M25/01
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/00862 , A61B2017/00867 , A61B2017/1205 , A61B2017/12063
摘要： The present invention provides an embolic assembly delivery apparatus having superior flexibility characteristics at its distal end, that is, at the point of attachment of the embolic assembly to the delivery apparatus. It also provides a method of using the apparatus to deliver an embolic assembly to a target site in a patient's body.
摘要翻译：本发明提供一种栓塞组件输送装置，其在其远端具有优异的柔性特性，即在栓塞组件与输送装置的连接点处。它还提供了一种使用该装置将栓塞组件递送到患者身体中的目标部位的方法。

4. 发明申请

US20070213764A1 Occlusive Cinching Devices and Methods of Use 有权
标题翻译：闭塞切割装置和使用方法
公开(公告)号：US20070213764A1
公开(公告)日：2007-09-13
申请号：US11748221
申请日：2007-05-14
申请人： Tri Tran , Kim Nguyen , Hanh Ho , My Doan , Richard Murphy , Michael Wallace , Clifford Teoh
发明人： Tri Tran , Kim Nguyen , Hanh Ho , My Doan , Richard Murphy , Michael Wallace , Clifford Teoh
IPC分类号： A61M29/00
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B2017/1205 , A61B2017/12063
摘要： Methods and devices for blocking orifices and occluding cavities within a patient are provided. The device in one variation comprises first and second tubular members attached to a collapsible sealing element. The device can be placed through an orifice and the collapsible sealing element can be collapsed to seal the orifice. An embolic may be introduced distal to the sealing element to occlude a cavity. The device may incorporate a locking mechanism which can be engaged to lock the sealing element into the collapsed position. The device may incorporate a valve to prevent flow through the tubular members, for example to prevent egress of the embolic from a cavity. The device can be detached to provide a permanent seal of the orifice, and can retain the embolic within the cavity. The device may be used in conjunction with a stent or other retention device to assist the sealing element in maintaining the seal.
摘要翻译：提供了用于阻断患者内的孔和闭塞腔的方法和装置。一个变型中的装置包括附接到可折叠密封元件的第一和第二管状构件。该装置可以通过孔口放置，并且可折叠密封元件可以折叠以密封孔口。可以在密封元件的远侧引入栓塞以封闭空腔。该装置可以包括可以接合以将密封元件锁定到折叠位置的锁定机构。该装置可以包括阀以防止流过管状构件，例如以防止栓塞从空腔排出。该装置可以被拆卸以提供孔口的永久性密封，并且可以将栓塞保持在空腔内。该装置可以与支架或其它保持装置结合使用以帮助密封元件保持密封。

5. 发明授权

US09055948B2 Vaso-occlusive devices comprising complex-shape proximal portion and smaller diameter distal portion 有权
标题翻译：包括复杂形状近端部分和较小直径远端部分的血管闭塞装置
公开(公告)号：US09055948B2
公开(公告)日：2015-06-16
申请号：US11270035
申请日：2005-11-09
申请人： Kevin M. Jaeger , Clifford Teoh
发明人： Kevin M. Jaeger , Clifford Teoh
IPC分类号： A61M29/00 , A61B17/12 , A61L31/02
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B2017/12054 , A61B2017/12063 , A61L31/022
摘要： This is a device for occluding a space within the body. In particular, the device comprises a proximal portion having a complex, three-dimensional shape and a distal portion, where the diameter of the shape defined by the distal portion is smaller than the diameter of the shape defined by the proximal portion. The devices may be placed in a desired site within a mammal and are useful in occluding devices.
摘要翻译：这是一个用于遮挡体内空间的装置。特别地，该装置包括具有复杂的三维形状和远端部分的近端部分，其中由远侧部分限定的形状的直径小于由近端部分限定的形状的直径。装置可以放置在哺乳动物内的期望的位置，并且可用于阻塞装置。

6. 发明授权

US08968352B2 Expandable body cavity liner device 有权
标题翻译：可扩展体腔衬垫装置
公开(公告)号：US08968352B2
公开(公告)日：2015-03-03
申请号：US10631928
申请日：2003-07-31
申请人： Clifford Teoh , Joseph C. Eder , Michael P. Wallace , Stephen C. Porter , David C. Barry , Amol Parkar
发明人： Clifford Teoh , Joseph C. Eder , Michael P. Wallace , Stephen C. Porter , David C. Barry , Amol Parkar
IPC分类号： A61M29/00 , A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12172
摘要： The present invention is a method for treating aneurysms of various shapes and sizes.
摘要翻译：本发明是一种治疗各种形状和大小的动脉瘤的方法。

7. 发明申请

US20100160944A1 Thermally detachable embolic assemblies 审中-公开
标题翻译：热分解栓塞组件
公开(公告)号：US20100160944A1
公开(公告)日：2010-06-24
申请号：US12589756
申请日：2009-10-28
申请人： Clifford Teoh , John M. K. Daniel
发明人： Clifford Teoh , John M. K. Daniel
IPC分类号： A61M29/00 , A61F2/06 , C09J5/00
CPC分类号： A61B17/12022 , A61B17/12145 , A61B17/12154 , A61B2017/12068 , A61L31/048 , A61L31/06 , A61L2430/36 , C08L23/12 , C08L23/08 , C08L67/02 , C08L77/06
摘要： Disclosed herein are vaso-occlusive assemblies for deploying implantable devices into the vasculature of a patient. More particularly, disclosed herein are vaso-occlusive assemblies comprising at least one thermally detachable polymer structure permanently attached to the implantable device and non-permanently attached to the delivery device prior to deployment. Also described are methods of making and using these assemblies.
摘要翻译：本文公开了用于将可植入装置部署到患者的脉管系统中的血管闭塞组件。更具体地，本文公开了包含至少一个热可分离聚合物结构的血管闭塞组件，其永久地附接到可植入装置并且在部署之前非永久性地附接到递送装置。还描述了制造和使用这些组件的方法。

8. 发明申请

US20090062726A1 MEDICAL IMPLANT DETACHMENT SYSTEMS AND METHODS 有权
标题翻译：医用植入物分离体系及方法
公开(公告)号：US20090062726A1
公开(公告)日：2009-03-05
申请号：US12122636
申请日：2008-05-16
申请人： Russell Ford , Scott McGill , Clifford Teoh , Michael Williams , Kamal Ramzipoor , Like Que , Ann Huang , Elena Oo , Christina Ma , Stella Chu
发明人： Russell Ford , Scott McGill , Clifford Teoh , Michael Williams , Kamal Ramzipoor , Like Que , Ann Huang , Elena Oo , Christina Ma , Stella Chu
IPC分类号： A61B17/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/00022 , A61B2017/12063
摘要： An implant assembly comprises an elongated pusher member, and an implantable device (e.g., a vaso-occlusive device) mounted to the distal end of the pusher member. The implant assembly further comprises an electrolytically severable joint disposed on the pusher member, wherein the implantable device detaches from the pusher member when the severable joint is severed, and a return electrode carried by the distal end of the pusher member (e.g., a coil disposed about the pusher member) in proximity to, but electrically isolated from, the severable joint. The implant assembly further comprises a terminal carried by the proximal end of the pusher member in electrical communication with the severable joint.
摘要翻译：植入物组件包括细长的推动器构件和安装到推动器构件的远端的可植入装置（例如，血管闭塞装置）。植入物组件还包括设置在推动器构件上的电解可分离的接头，其中当可切断接头被切断时，可植入装置与推动器构件分离，以及由推动器构件的远端（例如，线圈设置围绕推动器构件）接近，但是与可分开的接头电隔离。植入物组件还包括由推动器构件的近端承载的端子，其与可分离接头电连通。

9. 发明授权

US06929654B2 Non-overlapping spherical three-dimensional coil 有权
标题翻译：不重叠的球形三维线圈
公开(公告)号：US06929654B2
公开(公告)日：2005-08-16
申请号：US10634176
申请日：2003-08-04
申请人： Clifford Teoh , Michael P. Wallace
发明人： Clifford Teoh , Michael P. Wallace
IPC分类号： A61B17/00 , A61B17/12 , A61M29/00
CPC分类号： A61B17/12145 , A61B17/12022 , A61B17/1215 , A61B2017/00867
摘要： Vaso-occlusive devices with made of non-overlapping turns of a primary coil are described. Also described are methods of making and using these devices.
摘要翻译：描述了由初级线圈的非重叠匝构成的血管闭塞装置。还描述了制造和使用这些装置的方法。

10. 发明授权

US6013084A Stretch resistant vaso-occlusive coils (II) 失效
标题翻译：抗拉性血管闭塞线圈（II）
公开(公告)号：US6013084A
公开(公告)日：2000-01-11
申请号：US879408
申请日：1997-06-20
申请人： Christopher G. M. Ken , Joseph C. Eder , Clifford Teoh
发明人： Christopher G. M. Ken , Joseph C. Eder , Clifford Teoh
IPC分类号： A61B17/00 , A61B17/12 , A61B19/00 , A61F2/00 , A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/00867 , A61B2017/1205 , A61B2017/12063 , A61B2090/3937 , A61F2002/30093 , A61F2210/0019
摘要： This is an implantable vaso-occlusive device. It is typically a vaso-occlusive coil comprising a primary helically wound coil which may then be wound into a secondary shape. Central to the invention is the use of a stretch-resisting member extending through the lumen formed, which stretch-resisting member is fixedly attached, directly or indirectly, to the coil in at least two locations. The stretch-resisting member is preferably somewhat loose within the interior of the lumen so to prevent the coil from collapsing, binding, and therefore stiffening during passage of turns through the human body. The coil should bend easily. In some variations of the invention, the stretch-resisting member may be formed into coil tips at the ends of the coil using simple equipment such as soldering irons or the like. The tips are typically of the same diameter as is the coil body itself. This stretch-resisting member is for the primary purpose of preventing stretching of the coil during movement of that coil, e.g., by retrieval or repositioning after deployment. The device may have a self-forming secondary shape made from a pre-formed primary linear helically wound coil, although it need not have the secondary form. Desirably, the coil is extremely flexible and is controllaby released using a severable or mechanical joint such as an electrolytically detachable joint. External fibers may be attached to the device and affixed to the pre-formed linear member to increase thrombogenicity. The extremely flexible variation of the invention may be hydraulically delivered through the lumen of a catheter and is so flexible that it may be retrievably delivered therethrough a flow-directed catheter. The vaso-occlusive member may be also be covered with a fibrous braid. The device is typically introduced into the body through a catheter. The device is passed axially through the catheter sheath and assumes its secondary form upon exiting the catheter.
摘要翻译：这是一种植入式血管闭塞装置。它通常是包括初级螺旋缠绕线圈的血管闭塞线圈，然后可以将其缠绕成次级形状。本发明的中心在于在至少两个位置上使用延伸穿过形成的内腔的拉伸抵抗构件，该拉伸抵抗构件直接地或间接地固定到线圈上。拉伸阻力构件优选在内腔的内部稍微松动，从而防止线圈在匝穿过人体期间塌陷，结合并因此加强。线圈应弯曲容易。在本发明的一些变型中，可以使用诸如烙铁等的简单设备在线圈的端部处形成线圈尖端。尖端通常具有与线圈体本身相同的直径。该抗拉伸构件的主要目的是防止在线圈移动过程中线圈的拉伸，例如通过在展开后的取回或重新定位。该装置可以具有由预先形成的初级线性螺旋缠绕线圈制成的自成形次级形状，尽管它不需要具有二次形式。理想地，线圈非常柔软，并且使用可分离或机械接头（例如电解可拆卸接头）进行控制释放。外部纤维可以附着到装置上并固定到预先形成的线性构件上以增加血栓形成。本发明的极其灵活的变化可以通过导管的内腔液压输送，并且是如此柔性的，使得其可被可逆地递送通过其中的导向导管。血管闭塞性构件也可以用纤维编织物覆盖。该装置通常通过导管引入身体。该装置轴向穿过导管护套，并在离开导管时呈现其次级形式。

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