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    • 4. 发明申请
    • OXAZINE DISULFIDE DYES
    • WO2007039529A3
    • 2007-04-12
    • PCT/EP2006/066784
    • 2006-09-27
    • CIBA SPECIALTY CHEMICALS HOLDING INC.CREMER, ChristianWALLQUIST, Olof
    • CREMER, ChristianWALLQUIST, Olof
    • A61Q5/10A61K8/49C09B17/02C09B19/00C09B49/06
    • Disclosed are oxazine disulfide dyes of formula (1) D 1 ―(Z 1 ) r ―Y 1 ―S―A, wherein A is hydrogen; or a radical of formula (1a) *―S―Y 2 ―(Z 2 ) r ―D 2 ; Y 1 and Y 2 independently from each other are unsubstituted or substituted, straight-chain or branched, interrupted or uninterrupted C- 1 -C- 10 alkylene; C 5 -C 10 cycloalkylene; C 5 -C 10 arylene; or-C 5 -C 10 arylene-(C 1 -C 10 alkylene); Z 1 and Z 2 independently from each other are *-(CH 2 ) p -C(O)-**; *-(CH 2 CH 2 -O) s -**; *-(CH 2 ) p -C(O)O-**; *-(CH 2 ) p -OCO-**; *-(CH 2 ) P -N(R 1 )-**; formula 1(g); -(CH 2 ) P -CON(R 1 )-**; *-(CH 2 ) P -(R 1 )NC(O)-**; . - 0-; -S-; -S(O)-; -S(O) 2 -; or a cationic biradical of a substituted or unsubstituted aromatic or heteroaromatic compound of the formula (1a); (1b); (1c); (1d); or (1e); wherein the asterix * indicates the linkage to D 1 and/or D 2 ; the asterix ** indicates the linkage to Y 1 and/or Y 2 ; W 1 is N or a radical of CR 5 ; R 1 , R 2 , R 3 , R 4 and R 5 independently from each other are hydrogen; C 1 -C 14 alkyl; C 2 -C 14 alkenyl; C 5 -C 10 aryl; C 5 -C 10 aryl-(C 1 -C 10 alkyl) ; or -C 1 -C 10 alkyl(C 5 -C 10 aryl); D 1 and D 2 independently from each other ar the residue of an organic dye selected from the radical of formula (1f); R 6 and R 7 independently from each other are hydrogen; C 1 -C 20 alkyl; C 1 -C 20 alkoxy; C 3 -C 6 cycloalkyl; C 5 -C 10 aryl; anellated aromatic groups; carboxylate; or sulfonate groups; R 8 , R 9 and R 10 , R 11 and R 12 each independently from each other are hydrogen; unsubstituted or substituted, straight-chain or branched, monocyclic or polycyclic, interrupted or uninterrupted C 1 -C 14 alkyl, C 2 -C 14 alkenyl, C 6 -C 10 aryl, C 6 -C 10 aryl-C 1 -C 10 alkyl or C 5 -C 10 alkyl(C 5 -C 10 aryl); or R 8 and R 9 or R 10 and R 11 together with the linking nitrogen atom form a 5 to 7 membered carbocyclic ring which may contain one or more than one hetero atom; or R 8 is linked to C 1 together with N + forming a 5-7 membered carbocyclic ring; or R 9 is linked to C 2 together with N + forming a 5-7 membered carbocyclic ring; X is -O-; or -N(R 9 )-; or -S-; p is a number from 0 to 5; r is 0 or 1; and s is a number from 1 to 5. The compounds are useful for the dyeing of organic materials, such as keratin fibers, preferably human hair.
    • 6. 发明申请
    • SULFIDE DYES
    • WO2006136516A2
    • 2006-12-28
    • PCT/EP2006/063179
    • 2006-06-14
    • CIBA SPECIALTY CHEMICALS HOLDING INC.CREMER, ChristianWALLQUIST, Olof
    • CREMER, ChristianWALLQUIST, Olof
    • C09B1/002A61K8/355A61K8/46A61K8/4946A61Q5/065C09B1/207
    • Disclosed are compounds of formula. Method of dyeing keratin-containing fibers comprising treating the fiber with at least one sulfide dye of formula (1), their salts, isomers, hydrates and other solvates, wherein R 1 , R 2 , R 3 and R 4 independently from each other are hydrogen; C 1 -C 20 alkyl; C 1 -C 20 alkoxy; C 3 -C 6 cycloalkyl; halogen; NO 2 ; OH; SH; or a radical of formula (1a) wherein R 5 is hydrogen; or C 1 -C 20 alkyl; R 6 , R 7 and R 8 independently from each other are hydrogen, C 1 -C 20 alkyl, C 4 -C 12 cycloalkyl, C 6 -C 13 aralkyl; phenyl- C 1 -C 5 alkyl; or R 6 and R 7 together with the linking nitrogen atom form a C 4 -C 12 -membered heterocyclic ring which may be interrupted by one or more than one- O- or -NH- goups; Y 1 is C 1 -C 10 alkylene; C 5 -C 10 cycloalkylene; C 5 -C 10 arylene; or C 5 -C 10 arylene-( C 1 -C 10 alkylene); T 1 is a radical of formula (1b); or -O-(X 3 ) s ; Q 1 is a cationic biradical of a saturated, aromatic or heteroaromatic group; or a radical of formula (1c); Z 1 is -C(O)-; -(CH 2 CH 2 -O) 1-5 -; -C(O)O-; -OCO-; CON(R 9 )-; -X 4 -CON(R 9 )-; -(R 9 )NC(O)-; - O-; -S-; -S(O)-; or -S(O) 2 -; R 9 , R 10 and R 11 each independently from each other are hydrogen; C 1 -C 14 alkyl; C 2 -C 14 alkenyl; C 6 -C 10 aryl; C 6 -C 10 aryl- C 1 -C 10 alkyl; or C 1 -C 10 alkyl(C 5 -C 10 aryl); X 1 , X 2 , X 3 and X 4 independently from each other are C 1 -C 18 alkylene; -(CO)- C 1 -C 18 alkylene, C 1 -C 18 arylene; C 6 -C 18 arylene- C 1 -C 12 alkylene; or -(OCH 2 CH 2 ) n -O-; n is a number from 1 to 5; p, r, s, t and u independently from each other are a 0 or 1; m is 1; or 2; U is hydrogen, if m is 1; and U is the direct bond, if m is 2. The compounds are useful for the dyeing of organic materials, such as keratin fibers, preferably human hair. The dyes are distinguished by deep dying having good fastness properties with respect to washing, light, shampooing and rubbing.
    • 公开了式的化合物。 染色含有角蛋白的纤维的方法,包括用至少一种式(1)的硫化染料,其盐,异构体,水合物和其它溶剂化物处理纤维,其中R 1,R 2, R 3,R 3和R 4彼此独立地是氢; ç 1 -C 20 烷基; ç 1 -C 20 烷氧基; ç 3 -C 6 环烷基; 卤素; NO 2 ; 哦; SH; 或其中R 5为氢的式(1a)基团; 或C 1 -C 20烷基; R 6,R 7和R 8彼此独立地是氢,C 1 -C 3 - 20个C 1 -C 12烷基,C 4 -C 12环烷基,C 6 -C 13芳烷基, 苯基-C 1 -C 5烷基; 或R 6和R 7与连接氮原子一起形成C 4-14碳 - 12个杂环基 环可能被一个或多于一个O-或-NH-羟基中断; Y 1是C 1 -C 10亚烷基; ç 5 -C 10 亚环烷基; ç 5 -C 10 亚芳基; 或C 5 -C 10亚芳基 - (C 1 -C 10亚烷基); T 1是式(1b)的基团; 或-O-(X 3 N 3)3。 Q 1是饱和,芳族或杂芳族基团的阳离子双基; 或式(1c)的基团; Z 1是-C(O) - ; - (CH 2 CH 2 -O) 1-5 - ; -C(O)O-; -OCO-; CON(R 9 ) - ; -X 4 -CON(R 9 ) - ; - (R 9 )NC(O) - ; - O- -S-; -所以)-; 或-S(O)2 - ; R 9,R 10和R 11各自独立地为氢; ç 1 -C 14 烷基; ç 2 -C 14 烯基; ç 6 -C 10 芳基; C 6 -C 10芳基-C 1 -C 10烷基; C 1 -C 6烷基; 或C 1 -C 10烷基(C 5 -C 10芳基);或C 1 -C 10烷基。 X 1,X 2,X 3和X 4彼此独立地为C 1, / SUB> -C 18 亚烷基; - (CO)-C 1 -C 18亚烷基,C 1 -C 18亚芳基; C 6 -C 18亚芳基-C 1 -C 12亚烷基; 或 - (OCH 2 CH 2 CH 2)n -O-; n是从1到5的数字; p,r,s,t和u彼此独立地为0或1; m为1; 或2; U是氢,如果m是1; 如果m为2,则U是直接键合。该化合物可用于染色有机材料,例如角蛋白纤维,优选人发。 这些染料的特征在于具有相对于洗涤,光,洗发和摩擦的良好牢度性质的深度染色。