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1. 发明授权

US06589573B2 Xanthine oxidase inhibitor and method for producing the same 有权
公开(公告)号：US06589573B2
公开(公告)日：2003-07-08
申请号：US10013351
申请日：2001-12-13
申请人： Tomonori Unno , Iwao Sakane , Takami Kakuda
发明人： Tomonori Unno , Iwao Sakane , Takami Kakuda
IPC分类号： A61K3578
CPC分类号： A61K36/185
摘要： In order to provide a xanthine oxidase inhibitor having as an effective component an extract from highly safe plants, ten kinds of plant materials were compared for the xanthine oxidase inhibition activity, and in consequence Lagerstroemia speciosa (banaba) was found to have the strongest activity. In addition, it was found that the xanthine oxidase inhibition activity was present in an “crude extract” obtained by extracting banaba with hot water or the like, “resin adsorbed components” obtained by adsorbing the crude extract on a styrene-divinyl benzene synthetic resin or the like, and “organic solvent soluble components” obtained by the partition of the resin adsorbed component between water and an organic solvent. Among them, the “organic solvent soluble components” described above were purified with high performance liquid chromatography to obtain “ellagic acid,” an “ellagic acid derivative,” an “ellagic acid analog compound” and a “lignan,” which were found to have a more superior xanthine oxidase inhibitor activity. The present invention provides a xanthine oxidase inhibitor having each of these extracted materials as an effective component.

2. 发明申请

US20090156662A1 Fat Absorption Inhibitor 审中-公开
标题翻译：脂肪吸收抑制剂
公开(公告)号：US20090156662A1
公开(公告)日：2009-06-18
申请号：US12226672
申请日：2007-04-09
申请人： Ayumu Nozawa , Makoto Kobayashi , Tomonori Unno
发明人： Ayumu Nozawa , Makoto Kobayashi , Tomonori Unno
IPC分类号： A61K31/353 , A61P3/04
CPC分类号： A23K50/48 , A23F3/163 , A23F5/243 , A23K20/10 , A23K20/121 , A23L2/52 , A23L33/10 , A23L33/105 , A23L33/20 , A61K31/353 , A61K36/82
摘要： Disclosed is a composition or beverage/food for inhibiting the fat absorption, which is derived from a natural material and therefore is safe, and which can be ingested continuously. The composition or beverage/food comprises the following components: (A) theaflavine monogallate; (B) theaflavine; (C) theaflavine digallate; and (D) polyphenol, wherein these components satisfy the following requirements: (1) a weight-based content ratio [(A)/(B)] is 0.4-100%; (2) the weight of the component (A) is larger that that of the component (C); and (3) a weight-based content ratio [A)/(D)] is 0.01-1.0%. The composition or beverage/food can be used for the prevention or treatment of a disease such as arteriosclerosis and an ischemic heart disease (e.g., angina pectoris, myocardial infarction).
摘要翻译：公开了一种用于抑制脂肪吸收的组合物或饮料/食品，其衍生自天然材料，因此是安全的，并且可以连续摄取。组合物或饮料/食品包含以下成分：（A）茶黄素单糖酸酯; （B）茶黄素; （C）茶黄素; 和（D）多酚，其中这些组分满足以下要求：（1）重量含量比[（A）/（B）]为0.4-100％; （2）组分（A）的重量大于组分（C）的重量; 和（3）重量含量比[A] /（D）]为0.01〜1.0％。组合物或饮料/食物可用于预防或治疗诸如动脉硬化和缺血性心脏病（例如心绞痛，心肌梗塞）的疾病。

3. 发明申请

US20070172530A1 Beverage 有权
标题翻译：饮料
公开(公告)号：US20070172530A1
公开(公告)日：2007-07-26
申请号：US11338746
申请日：2006-01-25
申请人： Tomonori Unno , Ayumu Nozawa , Yuko Suzuki
发明人： Tomonori Unno , Ayumu Nozawa , Yuko Suzuki
IPC分类号： A61K36/82 , A23F3/00
CPC分类号： A23F3/163 , A23F3/18 , A61K36/82
摘要： A beverage is prepared, which is a beverage containing catechin in ester form (A), catechin in free form (B), and caffeine (C), the contents thereof being (A)+(B)=500 to 6000 mg/L (1) (A)/[(A)+(B)]=0.7 to 1.0 (2) (A)/(C)=6 to 27, (3) to maintain a high concentration of catechin with high biological functionality, with improved flavor and improved product quality in regard to occurrence of sediment and the like.
摘要翻译：制备饮料，其是含有酯形式（A）的儿茶素，游离形式的儿茶素类（B）和咖啡因（C）的饮料，其含量为<？in-line-formula description =“在线式 “end =”lead“？>（A）+（B）= 500〜6000 mg / L（1）<？in-line-formula description =”In-line Formulas“end =”tail“？> -line-formula description =“In-line Formulas”end =“lead”？>（A）/ [（A）+（B）] = 0.7〜1.0（2）<？in-line-formula description =“In （A）/（C）= 6〜27，（3）<？在线公式描述=“内联式”结束=“尾”？>以保持高浓度的具有高生物功能的儿茶素，具有改善的风味和改善的关于沉淀物等的发生的产品质量。

4. 发明申请

US20100068363A1 BEVERAGE COMPRISING CATECHINS AND CAFFEINE 审中-公开
标题翻译：包含CATECHINS和CAFFEINE的饮料
公开(公告)号：US20100068363A1
公开(公告)日：2010-03-18
申请号：US12626177
申请日：2009-11-25
申请人： Tomonori UNNO , Ayumu Nozawa , Yuko Suzuki
发明人： Tomonori UNNO , Ayumu Nozawa , Yuko Suzuki
IPC分类号： A23F3/16
CPC分类号： A23F3/163 , A23F3/18 , A61K36/82
摘要： A beverage is prepared, which is a beverage containing catechins in ester form (A, mg/L), catechins in free form (B, mg/L), and caffeine (C, mg/L), the contents thereof being (1) (A+B)=500 to 6000 mg/L (2) (A)/(A+B)=0.7 to 1.0 (3) (A)/(C)=6 to 27, such that a high concentration of catechins with high biological functionality, improved flavor and improved product quality with low occurrence of sediment is maintained.
摘要翻译：制备饮料，其为含有酯形式的儿茶素类（A，mg / L），游离形式的儿茶素类（B，mg / L）和咖啡因（C，mg / L）的饮料，其含量为（1 ）（A + B）= 500〜6000mg / L（2）（A）/（A + B）= 0.7〜1.0（3）（A）/（C）= 6〜27，具有高生物功能的儿茶素，改善风味和改善的产品质量，并保持低沉积物的发生。

5. 发明授权

US07666452B2 Beverage comprising cathechins and caffeine 有权
标题翻译：饮料包括导管和咖啡因
公开(公告)号：US07666452B2
公开(公告)日：2010-02-23
申请号：US11338746
申请日：2006-01-25
申请人： Tomonori Unno , Ayumu Nozawa , Yuko Suzuki
发明人： Tomonori Unno , Ayumu Nozawa , Yuko Suzuki
IPC分类号： A61K36/82
CPC分类号： A23F3/163 , A23F3/18 , A61K36/82
摘要： A beverage is prepared, which is a beverage containing catechins in ester form (A, mg/L), catechins in free form (B, mg/L), and caffeine (C, mg/L), the contents thereof being (A+B)=500 to 6000 mg/L (1) (A)/(A+B)=0.7 to 1.0 (2) (A)/(C)=6 to 27, (3) such that a high concentration of catechins with high biological functionality, improved flavor and improved product quality with low occurrence of sediment is maintained.
摘要翻译：制备饮料，其为含有酯形式的儿茶素（A，mg / L），游离形式的儿茶素类（B，mg / L）和咖啡因（C，mg / L）的饮料，其含量为（A + B）= 500〜6000mg / L（1）（A）/（A + B）= 0.7〜1.0（2）（A）/（C）= 6〜27，（3）具有高生物功能的儿茶素，改善风味和改善的产品质量，并保持低沉积物的发生。

6. 发明申请

US20090047408A1 Method for Improving Absorbability of Epigallocatechin Gallate, Foods, Drinks and Food/Drink Materials Using the Same and Method for Producing the Same 审中-公开
标题翻译：提高表儿基儿茶素镓酸盐，食品，饮料和食品/饮料的吸收性能的方法及其制备方法
公开(公告)号：US20090047408A1
公开(公告)日：2009-02-19
申请号：US12085959
申请日：2006-12-01
申请人： Tomonori Unno , Takami Kakuda , Teruo Miyazawa , Kiyotaka Nakagawa
发明人： Tomonori Unno , Takami Kakuda , Teruo Miyazawa , Kiyotaka Nakagawa
IPC分类号： A23F3/14
CPC分类号： A23F3/20 , A23F3/163 , A23L2/52 , A23L33/10 , A23L33/105 , A61K9/0095 , A61K9/08 , A61K31/7048 , A61K36/82 , A61K47/22
摘要： Provided are a food, a drink and a food/drink material having improved EGCg absorbability, and a method of producing the same, by improving the absorbability of EGCg to be taken in. The contents of caffeine and/or epigallocatechin gallate are regulated so that the ratio by mass of caffeine to epigallocatechin gallate contained in a food, drink, food/drink material or oral ingesta comes close to 0.4.
摘要翻译：提供具有改善的EGCg吸收性的食品，饮料和食品/饮料材料及其制备方法，通过改善吸收的EGCg的吸收性。调节咖啡因和/或表没食子儿茶素没食子酸酯的含量，使得食物，饮料，食物/饮料或口服摄入中所含的咖啡因与表没食子儿茶素没食子酸酯的质量比例接近0.4。

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