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1. 发明授权

US08170662B2 Method and apparatus for charging partitioned capacitors 失效
标题翻译：对分隔电容器进行充电的方法和装置
公开(公告)号：US08170662B2
公开(公告)日：2012-05-01
申请号：US11462301
申请日：2006-08-03
申请人： Joseph M. Bocek , Gregory J. Sherwood
发明人： Joseph M. Bocek , Gregory J. Sherwood
IPC分类号： A61N1/36
CPC分类号： H01G9/28 , A61N1/375 , A61N1/39 , A61N1/3968 , H01G9/008 , H01L28/40 , H02J7/0013 , H02J7/345
摘要： One aspect of this disclosure relates to an apparatus for providing a selective capacitance. An embodiment of the apparatus includes a first and second capacitor in a stack, and a switching circuit connected between the first and second capacitors. The switching circuit has at least two states, and is adapted to provide a first defibrillation capacitance in a first state and a second defibrillation capacitance in a second state. A switching circuit embodiment includes a field effect transistor (FET) adapted to have a source connected to the first capacitor and a drain connected to the second capacitor, a bipolar junction transistor (BJT) adapted to have an emitter connected to the source of the FET and a collector connected to a gate of the FET, a first current source connected to the collector of the BJT, and a second current source connected to a base of the BJT.
摘要翻译：本公开的一个方面涉及一种用于提供选择性电容的装置。该装置的实施例包括堆叠中的第一和第二电容器，以及连接在第一和第二电容器之间的开关电路。开关电路具有至少两个状态，并且适于在第二状态下提供第一除颤电容和第二除颤电容。开关电路实施例包括适于具有连接到第一电容器的源极和连接到第二电容器的漏极的场效应晶体管（FET），适于具有连接到FET源极的发射极的双极结型晶体管（BJT）和连接到FET的栅极的集电极，连接到BJT的集电极的第一电流源和连接到BJT的基极的第二电流源。

2. 发明授权

US07991470B2 Post-shock recovery monitoring for tachyarrhythmia discrimination 有权
标题翻译：急性心律失常辨别后的休克恢复监测
公开(公告)号：US07991470B2
公开(公告)日：2011-08-02
申请号：US12056684
申请日：2008-03-27
申请人： Jaeho Kim , Joseph M. Bocek , Eric G. Lovett
发明人： Jaeho Kim , Joseph M. Bocek , Eric G. Lovett
IPC分类号： A61N1/365
CPC分类号： A61B5/0464 , A61N1/3925 , A61N1/3962
摘要： A cardiac rhythm management device is configured to discriminate between ventricular and supraventricular tachycardias (referred to as SVT/VT discrimination) by utilizing a morphology criterion in which the morphology of electrogram waveforms during ventricular beats are analyzed to determine if the beats are normally conducted. After the delivery of a cardioversion/defibrillation shock, however, the intraventricular conduction system is left in a modified state which alters the subsequently generated electrogram signal. Use of the morphology criterion for SVT/VT discrimination is discontinued after delivery of such a shock and resumed after a predetermined minimum number of normally conducted ventricular beats has been detected.
摘要翻译：心律管理装置被配置为通过利用形态学标准来区分心室和室上性心动过速（称为SVT / VT鉴别），其中分析心室搏动时的电描记图波形的形态以确定节拍是否正常进行。然而，在输出心脏复律/除颤休克之后，心室内传导系统处于改变随后产生的电描记图信号的修改状态。在发生这种休克后，停止使用SVT / VT鉴别的形态学标准，并且在检测到预定的最小数量的正常进行的心室搏动之后恢复。

3. 发明申请

US20110160786A1 IMPLANTABLE DEVICE FAILSAFE MODE FOR MRI 有权
标题翻译：用于MRI的可植入器件失效模式
公开(公告)号：US20110160786A1
公开(公告)日：2011-06-30
申请号：US12976876
申请日：2010-12-22
申请人： Scott R. Stubbs , Joseph M. Bocek , Hiten J. Doshi
发明人： Scott R. Stubbs , Joseph M. Bocek , Hiten J. Doshi
IPC分类号： A61N1/365 , A61N1/36 , A61N1/39
CPC分类号： A61N1/37 , A61N1/3688 , A61N1/3718
摘要： An implantable device, such as a pacer, defibrillator, or other cardiac rhythm management device, can include a failsafe backup, such as a separate and independent safety core that can assume control over operation of the implantable device from a primary controller. In an example, the safety core can include a normal first safety core operating mode and a magnetic resonance imaging (MRI) second safety core operating mode that can provide different functionality from the normal first safety core operating mode.
摘要翻译：诸如起搏器，除颤器或其他心律管理装置的可植入装置可以包括故障安全备用，诸如独立且独立的安全核心，其可以承担对来自主控制器的可植入装置的操作的控制。在一个示例中，安全核心可以包括正常的第一安全核心操作模式和可以提供与正常的第一安全核心操作模式不同的功能的磁共振成像（MRI）第二安全核心操作模式。

4. 发明授权

US07818056B2 Blending cardiac rhythm detection processes 有权
标题翻译：混合心律检测过程
公开(公告)号：US07818056B2
公开(公告)日：2010-10-19
申请号：US11089185
申请日：2005-03-24
申请人： Jaeho Kim , Joseph M. Bocek , Julie A. Thompson , Eric G. Lovett
发明人： Jaeho Kim , Joseph M. Bocek , Julie A. Thompson , Eric G. Lovett
IPC分类号： A61N1/39
CPC分类号： A61N1/3962 , A61B5/04525 , A61B5/7264 , A61N1/3622 , A61N1/3925 , A61N1/395
摘要： Systems and methods are described for classifying a cardiac rhythm. A cardiac rhythm is classified using a classification process that includes a plurality of cardiac rhythm discriminators. Each rhythm discriminator provides an independent classification of the cardiac rhythm. The classification process is modified if the modification is likely to produce enhanced classification results. The rhythm is reclassified using the modified classification process.
摘要翻译：描述了用于分类心律的系统和方法。使用包括多个心律识别器的分类处理对心律进行分类。每个节律鉴别器提供心脏节律的独立分类。如果修改可能产生增强的分类结果，则修改分类过程。使用修改的分类过程重新分类节奏。

5. 发明授权

US07756578B2 Rhythm discrimination of sudden onset and one-to-one tachyarrythmia 失效
标题翻译：突发性和一对一快速性心律失常的节律辨别
公开(公告)号：US07756578B2
公开(公告)日：2010-07-13
申请号：US11276213
申请日：2006-02-17
申请人： Jaeho Kim , Joseph M. Bocek
发明人： Jaeho Kim , Joseph M. Bocek
IPC分类号： A61B5/0464
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3622 , A61N1/3925 , A61N1/3962 , G06F19/00
摘要： This document discusses, among other things, systems and methods to discriminate between a ventricular tachyarrhythmia (VT) and a supraventricular tachyarrhythmia (SVT), such as upon detecting sudden onset and one-to-one tachycardia. In certain examples, a detected tachyarrhythmia is analyzed to determine whether it is sudden onset and 1:1. If so, a first fast beat is identified. One or more ventricular intervals in close proximity to the first fast beat are analyzed to determine an initial classification of either VT or SVT. The initial classification is used to adjust a morphological feature correlation coefficient (FCC) threshold. A morphology analysis is performed with the adjusted FCC threshold value to yield a secondary classification.
摘要翻译：本文件尤其涉及区分心室性心律失常（VT）和室上性快速性心律失常（SVT）的系统和方法，例如在检测到突发性发作和一对一心动过速时。在某些实例中，分析检测到的快速性心律失常以确定其是否突然发作和1：1。如果是这样，首先确定快节拍。分析紧邻第一快节拍的一个或多个心室间隔以确定VT或SVT的初始分类。初始分类用于调整形态特征相关系数（FCC）阈值。用调整的FCC阈值进行形态分析以产生次级分类。

6. 发明授权

US07599738B2 Synchronized ventricular pacing to promote atrial sensing 失效
标题翻译：同步心室起搏以促进心房传感
公开(公告)号：US07599738B2
公开(公告)日：2009-10-06
申请号：US11130671
申请日：2005-05-17
申请人： Jaeho Kim , Joseph M. Bocek , Anthony S. Harrington
发明人： Jaeho Kim , Joseph M. Bocek , Anthony S. Harrington
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/3682
摘要： Methods and systems are described that involve synchronized ventricular pacing that promotes sensing of atrial events. The atrioventricular pacing delay is modified based on characteristics of previously sensed atrial events. The modified AV delay is implemented relative to a first atrial event. A second AV delay is implemented relative to a second atrial event if the second atrial event is sensed during the modified AV delay. A ventricular pacing pulse is delivered following the second AV delay.
摘要翻译：描述了涉及促进心房事件感测的同步心室起搏的方法和系统。房室起搏延时根据以前感测到的心房事件的特征进行修改。修改的AV延迟相对于第一次心房事件实现。如果在修改的AV延迟期间感测到第二心房事件，则相对于第二心房事件实施第二AV延迟。在第二次AV延迟之后递送心室起搏脉冲。

7. 发明授权

US07580740B2 Atrial tachyarrhythmia detection using selected atrial intervals 有权
标题翻译：使用选择的心房间隔进行心房快速性心律失常检测
公开(公告)号：US07580740B2
公开(公告)日：2009-08-25
申请号：US11126594
申请日：2005-05-11
申请人： Jaeho Kim , Joseph M. Bocek , Anthony S. Harrington , Harley G. White
发明人： Jaeho Kim , Joseph M. Bocek , Anthony S. Harrington , Harley G. White
IPC分类号： A61N1/37 , A61N1/362
CPC分类号： A61N1/3702 , A61B5/0464 , A61N1/3622
摘要： Methods and systems are directed to detecting atrial tachyarrhythmia. A plurality of A-A intervals is detected. The detected A-A intervals are selected and used to detect atrial tachyarrhythmia. Selecting A-A intervals may be based on determining that A-A intervals are qualified. Qualified A-A intervals may be determined if a duration of the particular A-A interval falls outside a predetermined duration range, for example. Qualified A-A intervals may also be determined based on events occurring between consecutively sensed atrial events of the particular A-A interval, and whether the duration of the particular A-A interval falls within the predetermined duration range, for example.
摘要翻译：方法和系统旨在检测房性快速性心律失常。检测到多个A-A间隔。检测到的A-A间隔被选择并用于检测房性快速性心律失常。选择A-A间隔可以基于确定A-A间隔是合格的。例如，如果特定A-A间隔的持续时间落在预定的持续时间范围之外，则可以确定合格的A-A间隔。也可以基于特定A-A间隔的连续感测的心房事件之间发生的事件以及特定A-A间隔的持续时间是否落入预定持续时间范围内来确定合格的A-A间隔。

8. 发明申请

US20080243201A1 PACER WITH COMBINED DEFIBRILLATOR TAILORED FOR BRADYCARDIA PATIENTS 审中-公开
标题翻译：用于BRADYCARDIA患者定期使用的组合式除颤器的PACER
公开(公告)号：US20080243201A1
公开(公告)日：2008-10-02
申请号：US12135709
申请日：2008-06-09
申请人： Joseph M. Bocek , Richard M. Dujmovic , Phil Foshee , Harley White , Jaeho Kim , Anthony Harrington , Richard S. Sanders , Douglas R. Daum , Paul De Coriolis , Joseph Smith , Richard Fogoros
发明人： Joseph M. Bocek , Richard M. Dujmovic , Phil Foshee , Harley White , Jaeho Kim , Anthony Harrington , Richard S. Sanders , Douglas R. Daum , Paul De Coriolis , Joseph Smith , Richard Fogoros
IPC分类号： A61N1/39 , A61N1/362
CPC分类号： A61N1/3956 , A61N1/3962
摘要： A combination pacer/defibrillator is tailored for bradycardia patients. In one example, its shock-delivery specificity exceeds its sensitivity to shockable ventricular tachyarrhythmias. In another example, its specificity exceeds 95%, or 99%, or even 99.5%. Sensitivity is programmed to a high desired sensitivity value, but only if it can be done without decreasing the specificity below the desired specificity threshold value. This can be conceptualized as “avoiding at all costs” delivering false shocks, even at the expense of failing to deliver a shock to a treatable ventricular tachyarrhythmia. Specificity enhancements include, among other things, inhibiting shock delivery when the patient is breathing or not supine, using multiple channels or a high rate VT/VF detection threshold. The present pacer/defibrillator device could potentially save the lives of bradyarrhythmia patients who are not presently clinically indicated for a defibrillator/pacer, but who have an increased risk of sudden cardiac death due to one or more risk factors.
摘要翻译：组合起搏器/除颤器是为心动过缓患者量身打造的。在一个例子中，其冲击传递特异性超过其对可震荡室性快速性心律失常的敏感性。在另一个实例中，其特异性超过95％，或99％，甚至99.5％。灵敏度被编程为高期望的灵敏度值，但是只有在不降低低于所需特异性阈值的特异性的情况下才能进行。这可以被概念化为“不惜一切代价”，提供虚假的冲击，即使以不能对可治疗的室性快速性心律失常发生冲击为代价。特异性增强包括，当患者呼吸或不仰卧时，使用多个通道或高速率的VT / VF检测阈值来抑制冲击输送。本发明的起搏器/除颤器装置可能潜在地节省目前临床指示用于除颤器/止痛器但是由于一个或多个危险因素引起的心脏猝死风险增加的缓慢心律失常患者的生命。

9. 发明授权

US07031764B2 Cardiac rhythm management systems and methods using multiple morphology templates for discriminating between rhythms 有权
标题翻译：心律管理系统和方法使用多种形态学模板来区分节律
公开(公告)号：US07031764B2
公开(公告)日：2006-04-18
申请号：US10291200
申请日：2002-11-08
申请人： Mark Schwartz , Joseph M. Bocek , Jaeho Kim
发明人： Mark Schwartz , Joseph M. Bocek , Jaeho Kim
IPC分类号： A61B5/452 , A61N1/365
CPC分类号： A61N1/3956 , A61B5/04525
摘要： Multiple morphology templates for discliminating between rhythms have been used, such as supraventricular tachyarrhythmias (SVTs) and ventricular tachyarrhythmias (VTs), for delivering a countershock in response to a VT episode, but withholding delivery of such a countershock in response to an SVT episode. In certain examples, the particular morphology used for storing morphological features is selected at least in part using a sensor-indicated activity level of a subject, or a metabolic need of the subject.
摘要翻译：已经使用用于在节律之间进行偏离的多个形态学模板，例如室上性快速性心律失常（SVT）和室性快速性心律失常（VT），用于响应于VT发作而产生反冲突，但是为了响应于SVT发作而扣留了这种反冲。在某些实例中，用于存储形态特征的特定形态至少部分地使用受试者的传感器指示的活动水平或受试者的代谢需要。

10. 发明授权

US06584350B2 Apparatus and method for R-wave detection with dual dynamic sensitivities 有权
公开(公告)号：US06584350B2
公开(公告)日：2003-06-24
申请号：US09828461
申请日：2001-04-06
申请人： Jaeho Kim , Joseph M. Bocek
发明人： Jaeho Kim , Joseph M. Bocek
IPC分类号： A61N139
CPC分类号： A61N1/3956 , A61N1/36592 , A61N1/3987
摘要： An apparatus and method for delivering electrical shock therapy in order to treat atrial tachyarrhythmias such as fibrillation utilizes a dynamically varying threshold to detect R-waves and synchronously deliver a defibrillation shock.

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