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1. 发明申请

US20080243201A1 PACER WITH COMBINED DEFIBRILLATOR TAILORED FOR BRADYCARDIA PATIENTS 审中-公开
标题翻译：用于BRADYCARDIA患者定期使用的组合式除颤器的PACER
公开(公告)号：US20080243201A1
公开(公告)日：2008-10-02
申请号：US12135709
申请日：2008-06-09
申请人： Joseph M. Bocek , Richard M. Dujmovic , Phil Foshee , Harley White , Jaeho Kim , Anthony Harrington , Richard S. Sanders , Douglas R. Daum , Paul De Coriolis , Joseph Smith , Richard Fogoros
发明人： Joseph M. Bocek , Richard M. Dujmovic , Phil Foshee , Harley White , Jaeho Kim , Anthony Harrington , Richard S. Sanders , Douglas R. Daum , Paul De Coriolis , Joseph Smith , Richard Fogoros
IPC分类号： A61N1/39 , A61N1/362
CPC分类号： A61N1/3956 , A61N1/3962
摘要： A combination pacer/defibrillator is tailored for bradycardia patients. In one example, its shock-delivery specificity exceeds its sensitivity to shockable ventricular tachyarrhythmias. In another example, its specificity exceeds 95%, or 99%, or even 99.5%. Sensitivity is programmed to a high desired sensitivity value, but only if it can be done without decreasing the specificity below the desired specificity threshold value. This can be conceptualized as “avoiding at all costs” delivering false shocks, even at the expense of failing to deliver a shock to a treatable ventricular tachyarrhythmia. Specificity enhancements include, among other things, inhibiting shock delivery when the patient is breathing or not supine, using multiple channels or a high rate VT/VF detection threshold. The present pacer/defibrillator device could potentially save the lives of bradyarrhythmia patients who are not presently clinically indicated for a defibrillator/pacer, but who have an increased risk of sudden cardiac death due to one or more risk factors.
摘要翻译：组合起搏器/除颤器是为心动过缓患者量身打造的。在一个例子中，其冲击传递特异性超过其对可震荡室性快速性心律失常的敏感性。在另一个实例中，其特异性超过95％，或99％，甚至99.5％。灵敏度被编程为高期望的灵敏度值，但是只有在不降低低于所需特异性阈值的特异性的情况下才能进行。这可以被概念化为“不惜一切代价”，提供虚假的冲击，即使以不能对可治疗的室性快速性心律失常发生冲击为代价。特异性增强包括，当患者呼吸或不仰卧时，使用多个通道或高速率的VT / VF检测阈值来抑制冲击输送。本发明的起搏器/除颤器装置可能潜在地节省目前临床指示用于除颤器/止痛器但是由于一个或多个危险因素引起的心脏猝死风险增加的缓慢心律失常患者的生命。

2. 发明授权

US06889079B2 Method and system for characterizing supraventricular rhythm during cardiac pacing 有权
标题翻译：在心脏起搏期间表现室上节律的方法和系统
公开(公告)号：US06889079B2
公开(公告)日：2005-05-03
申请号：US10121944
申请日：2002-04-12
申请人： Joseph Bocek , Jaeho Kim , Anthony Harrington
发明人： Joseph Bocek , Jaeho Kim , Anthony Harrington
IPC分类号： A61N1/362
CPC分类号： A61N1/3622
摘要： A method and system for generating a characterization of one beat of a patient's supraventricular rhythm (SVR) involves performing such characterization while the heart is being paced. During SVR characterization, various pacing parameters are modified and the patient's supraventricular rhythm is characterized while the pacing parameters are modified. The SVR characterization process is effective in single and multiple chamber pacing modes.
摘要翻译：用于产生患者室上性节律（SVR）的一搏的表征的方法和系统涉及在心脏起搏时进行这种表征。在SVR表征期间，修改了各种起搏参数，并对患者的室上节律进行了表征，同时对起搏参数进行了修改。 SVR表征过程在单腔和多腔起搏模式中有效。

3. 发明申请

US20090043347A1 Method and system for characterizing supraventricular rhythm during cardiac pacing 有权
标题翻译：在心脏起搏期间表现室上节律的方法和系统
公开(公告)号：US20090043347A1
公开(公告)日：2009-02-12
申请号：US12283220
申请日：2008-09-10
申请人： Joseph Bocek , Jaeho Kim , Anthony Harrington , Harley White , Dave Perschbacher , Rebecca Davis
发明人： Joseph Bocek , Jaeho Kim , Anthony Harrington , Harley White , Dave Perschbacher , Rebecca Davis
IPC分类号： A61N1/37
CPC分类号： A61N1/3622
摘要： A method and system for generating a characterization of one beat of a patient's supraventricular rhythm (SVR) involves performing such characterization while the heart is being paced. During SVR characterization, various pacing parameters are modified and the patient's supraventricular rhythm is characterized while the pacing parameters are modified. The SVR characterization process is effective in single and multiple chamber pacing modes.
摘要翻译：用于产生患者室上性节律（SVR）的一搏的表征的方法和系统涉及在心脏起搏时进行这种表征。在SVR表征期间，修改了各种起搏参数，并对患者的室上节律进行了表征，同时对起搏参数进行了修改。 SVR表征过程在单腔和多腔起搏模式中有效。

4. 发明申请

US20080058880A1 SYSTEM AND METHOD FOR PACING 审中-公开
标题翻译：系统和方法
公开(公告)号：US20080058880A1
公开(公告)日：2008-03-06
申请号：US11469595
申请日：2006-09-01
申请人： Jaeho Kim , Joseph M. Bocek , Anthony Harrington
发明人： Jaeho Kim , Joseph M. Bocek , Anthony Harrington
IPC分类号： A61N1/00
CPC分类号： A61N1/365 , A61B5/0464 , A61B5/7203 , A61N1/3718
摘要： In an embodiment, an implantable medical device senses the heart rate of a patient by analyzing a cardiac signal of the patient. The device identifies an increase in the patient's sensed heart rate and determines whether noise in the cardiac signal exceeds a certain specified amount. Upon an increase in the sensed heart rate and a finding of noise in the cardiac signal, pacing is invoked in the patient at a normal rate or at a rate that is greater than an estimated intrinsic rate for that patient. The device continues to pace until the device determines that the noise in the cardiac signal has subsided.
摘要翻译：在一个实施例中，可植入医疗装置通过分析患者的心脏信号来感测患者的心率。该装置识别患者感测心率的增加，并确定心脏信号中的噪声是否超过某一特定量。在感测心率增加和心脏信号中发现噪声的情况下，起搏以正常速率或大于该患者的估计内在速率的速率在患者中调用。器件继续进行，直到器件确定心脏信号中的噪声已经消退。

5. 发明申请

US20060259089A1 Atrial tachyarrhythmia detection using selected atrial intervals 有权
公开(公告)号：US20060259089A1
公开(公告)日：2006-11-16
申请号：US11126594
申请日：2005-05-11
申请人： Jaeho Kim , Joseph Bocek , Anthony Harrington , Harley White
发明人： Jaeho Kim , Joseph Bocek , Anthony Harrington , Harley White
IPC分类号： A61N1/362
CPC分类号： A61N1/3702 , A61B5/0464 , A61N1/3622
摘要： Methods and systems are directed to detecting atrial tachyarrhythmia. A plurality of A-A intervals is detected. The detected A-A intervals are selected and used to detect atrial tachyarrhythmia. Selecting A-A intervals may be based on determining that A-A intervals are qualified. Qualified A-A intervals may be determined if a duration of the particular A-A interval falls outside a predetermined duration range, for example. Qualified A-A intervals may also be determined based on events occurring between consecutively sensed atrial events of the particular A-A interval, and whether the duration of the particular A-A interval falls within the predetermined duration range, for example.

6. 发明申请

US20060186268A1 AIRCRAFT CART TRANSPORT AND STOWAGE SYSTEM 有权
标题翻译：飞机运输和货运系统
公开(公告)号：US20060186268A1
公开(公告)日：2006-08-24
申请号：US10906465
申请日：2005-02-22
申请人： Anthony Harrington , Gary Bazzell
发明人： Anthony Harrington , Gary Bazzell
IPC分类号： B64D11/00
CPC分类号： B64D11/04 , B64D11/0007
摘要： An object transport and stowage system for an aircraft (10) includes a transport unit (32) for the transport of an object (20) within the aircraft (10). A first transfer drive system (62) is attached to the transport unit (32) and includes object engagement devices (92) that are engagable with the object (20). A motor (120) is mechanically coupled to and rotates one or more of the object engagement devices (92). A controller (66) is electrically coupled to the motor (120) and translates the object (20) relative to the transport unit (32). Another object transport and stowage system for an aircraft (10) includes a housing (150) for the stowage of an object (20) on the aircraft (10). A transfer drive system (64) is attached to the housing (150) and includes object engagement devices (168, 176), which are engagable with the object (20). A motor (162) is mechanically coupled to and rotates one or more of the object engagement devices (168, 176). A controller (68) is electrically coupled to the motor (162) and translates the object (20) relative to the housing (150).
摘要翻译：用于飞机（10）的物体运输和存放系统包括用于运输飞机（10）内的物体（20）的运输单元（32）。第一传送驱动系统（62）附接到传送单元（32）并且包括可与物体（20）接合的物体接合装置（92）。电动机（120）机械地联接到并旋转物体接合装置（92）中的一个或多个。控制器（66）电耦合到电动机（120）并且相对于传送单元（32）平移物体（20）。用于飞机（10）的另一物体运输和存放系统包括用于在飞行器（10）上存放物体（20）的壳体（150）。转移驱动系统（64）附接到壳体（150）并且包括可与物体（20）接合的物体接合装置（168,176）。电动机（162）机械地联接到并旋转物体接合装置（168,176）中的一个或多个。控制器（68）电耦合到电动机（162）并且相对于壳体（150）平移物体（20）。

7. 发明授权

US06928323B2 Adaptive sensing threshold for cross-chamber refractory period 有权
$Adaptive sensing threshold for cross-chamber refractory period$
标题翻译：跨室不应期的自适应感应阈值
公开(公告)号：US06928323B2
公开(公告)日：2005-08-09
申请号：US10334217
申请日：2002-12-30
申请人： Jaeho Kim , Harley White , Anthony Harrington , Joseph M. Bocek
发明人： Jaeho Kim , Harley White , Anthony Harrington , Joseph M. Bocek
IPC分类号： A61N1/37
CPC分类号： A61N1/3704
摘要： A cross-chamber refractory period with an adaptively adjusted sensing threshold for use by a cardiac pacemaker is disclosed. In response to a cross-chamber event, the sensing threshold of a sensing channel is raised to an adaptively adjusted cross-chamber maximum refractory value. The cross-chamber maximum refractory value is derived from a peak amplitude measurement of the far-field signal resulting from the cross-chamber event.
摘要翻译：公开了一种由心脏起搏器使用的具有自适应调节的感测阈值的跨室不应期。响应于跨室事件，将感测通道的感测阈值提高到自适应调节的交叉室最大耐火值。横室最大难变值是从横室事件产生的远场信号的峰值振幅测量得出的。

8. 发明授权

US08301251B2 Atrial tachyarrhythmia detection using selected atrial intervals 有权
标题翻译：使用选择的心房间隔进行心房快速性心律失常检测
公开(公告)号：US08301251B2
公开(公告)日：2012-10-30
申请号：US13275529
申请日：2011-10-18
申请人： Jaeho Kim , Joseph Bocek , Anthony Harrington , Harley White
发明人： Jaeho Kim , Joseph Bocek , Anthony Harrington , Harley White
IPC分类号： A61N1/00
CPC分类号： A61N1/3702 , A61B5/0464 , A61N1/3622
摘要： Methods and systems are directed to detecting atrial tachyarrhythmia. A plurality of A-A intervals is detected. The detected A-A intervals are selected and used to detect atrial tachyarrhythmia. Selecting A-A intervals may be based on determining that A-A intervals are qualified. Qualified A-A intervals may be determined if a duration of the particular A-A interval falls outside a predetermined duration range, for example. Qualified A-A intervals may also be determined based on events occurring between consecutively sensed atrial events of the particular A-A interval, and whether the duration of the particular A-A interval falls within the predetermined duration range, for example.
摘要翻译：方法和系统旨在检测房性快速性心律失常。检测到多个A-A间隔。检测到的A-A间隔被选择并用于检测房性快速性心律失常。选择A-A间隔可以基于确定A-A间隔是合格的。例如，如果特定A-A间隔的持续时间落在预定的持续时间范围之外，则可以确定合格的A-A间隔。也可以基于特定A-A间隔的连续感测的心房事件之间发生的事件以及特定A-A间隔的持续时间是否落入预定持续时间范围内来确定合格的A-A间隔。

9. 发明授权

US07426411B2 Method and system for characterizing supraventricular rhythm during cardiac pacing 有权
标题翻译：在心脏起搏期间表现室上节律的方法和系统
公开(公告)号：US07426411B2
公开(公告)日：2008-09-16
申请号：US11097458
申请日：2005-04-01
申请人： Joseph Bocek , Jaeho Kim , Anthony Harrington , Harley White , Dave Perschbacher , Rebecca Bloomfield Davis
发明人： Joseph Bocek , Jaeho Kim , Anthony Harrington , Harley White , Dave Perschbacher , Rebecca Bloomfield Davis
IPC分类号： A61N1/362
CPC分类号： A61N1/3622
摘要： A method and system for generating a characterization of one beat of a patient's supraventricular rhythm (SVR) involves performing such characterization while the heart is being paced. During SVR characterization, various pacing parameters are modified and the patient's supraventricular rhythm is characterized while the pacing parameters are modified. The SVR characterization process is effective in single and multiple chamber pacing modes.
摘要翻译：用于产生患者室上性节律（SVR）的一搏的表征的方法和系统涉及在心脏起搏时进行这种表征。在SVR表征期间，修改了各种起搏参数，并对患者的室上节律进行了表征，同时对起搏参数进行了修改。 SVR表征过程在单腔和多腔起搏模式中有效。

10. 发明授权

US07386344B2 Pacer with combined defibrillator tailored for bradycardia patients 失效
标题翻译：步行者联合除颤器为心动过缓患者量身打造
公开(公告)号：US07386344B2
公开(公告)日：2008-06-10
申请号：US10921777
申请日：2004-08-18
申请人： Joseph M. Bocek , Richard Milon Dujmovic, Jr. , Phil Foshee , Harley White , Jaeho Kim , Anthony Harrington , Richard S. Sanders , Douglas R. Daum , Paul De Coriolis , Joseph Smith , Richard Fogoros
发明人： Joseph M. Bocek , Richard Milon Dujmovic, Jr. , Phil Foshee , Harley White , Jaeho Kim , Anthony Harrington , Richard S. Sanders , Douglas R. Daum , Paul De Coriolis , Joseph Smith , Richard Fogoros
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3962
摘要： A combination pacer/defibrillator is tailored for bradycardia patients. In one example, its shock-delivery specificity exceeds its sensitivity to shockable ventricular tachyarrhythmias. In another example, its specificity exceeds 95%, or 99%, or even 99.5%. Sensitivity is programmed to a high desired sensitivity value, but only if it can be done without decreasing the specificity below the desired specificity threshold value. This can be conceptualized as “avoiding at all costs” delivering false shocks, even at the expense of failing to deliver a shock to a treatable ventricular tachyarrhythmia. Specificity enhancements include, among other things, inhibiting shock delivery when the patient is breathing or not supine, using multiple channels or a high rate VT/VF detection threshold. The present pacer/defibrillator device could potentially save the lives of bradyarrhythmia patients who are not presently clinically indicated for a defibrillator/pacer, but who have an increased risk of sudden cardiac death due to one or more risk factors.
摘要翻译：组合起搏器/除颤器是为心动过缓患者量身打造的。在一个例子中，其冲击传递特异性超过其对可震荡室性快速性心律失常的敏感性。在另一个实例中，其特异性超过95％，或99％，甚至99.5％。灵敏度被编程为高期望的灵敏度值，但是只有在不降低低于所需特异性阈值的特异性的情况下才能进行。这可以被概念化为“不惜一切代价”，提供虚假的冲击，即使以不能对可治疗的室性快速性心律失常发生冲击为代价。特异性增强包括，当患者呼吸或不仰卧时，使用多个通道或高速率的VT / VF检测阈值来抑制冲击输送。本发明的起搏器/除颤器装置可能潜在地节省目前临床指示用于除颤器/止痛器但是由于一个或多个危险因素引起的心脏猝死风险增加的缓慢心律失常患者的生命。

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