专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08911987B2 System for rapid identification and/or characterization of a microbial agent in a sample 有权
标题翻译：用于在样品中快速鉴定和/或表征微生物剂的系统
公开(公告)号：US08911987B2
公开(公告)日：2014-12-16
申请号：US12800388
申请日：2010-05-14
申请人： Ronnie J. Robinson , Mark S. Wilson , Christopher S. Ronsick , John D. Walsh , Jones M. Hyman , Bradford G. Clay
发明人： Ronnie J. Robinson , Mark S. Wilson , Christopher S. Ronsick , John D. Walsh , Jones M. Hyman , Bradford G. Clay
IPC分类号： C12M1/00 , C12M3/00 , G01N35/00 , C12Q1/24 , G01N35/10
CPC分类号： C12Q1/24 , G01N35/0099 , G01N35/1079 , Y10S901/30
摘要： An automated instrument for identification and/or characterization of a microbial agent present in a sample. The instrument includes (a) a sample removal apparatus operative to remove a test sample from a specimen container and add the test sample to a disposable separation device; (b) a separation and concentration apparatus operative on the separation device to separate the microbial agent from other components which may be present in the test sample and concentrate the microbial agent within the separation device; and (c) a identification and/or characterization module interrogating the concentrated microbial agent to identify and/or characterize the microbial agent.
摘要翻译：用于鉴定和/或表征样品中存在的微生物剂的自动化仪器。仪器包括（a）样品去除装置，用于从试样容器中取出测试样品，并将测试样品加入到一次性分离装置中; （b）分离和浓缩装置，其在分离装置上操作以将微生物剂与可能存在于测试样品中的其它组分分离，并将微生物剂浓缩在分离装置内; 和（c）识别和/或表征模块，询问浓缩的微生物剂以鉴定和/或表征微生物剂。

2. 发明授权

US08512975B2 Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements 有权
标题翻译：使用时间依赖光谱测量法检测和表征样品中微生物的方法
公开(公告)号：US08512975B2
公开(公告)日：2013-08-20
申请号：US12460607
申请日：2009-07-22
申请人： John D. Walsh , Jones M. Hyman , Bradford G. Clay , Thurman C. Thorpe
发明人： John D. Walsh , Jones M. Hyman , Bradford G. Clay , Thurman C. Thorpe
IPC分类号： C12Q1/04
CPC分类号： C12Q1/04 , C12Q1/10 , G01N21/31 , G01N21/47 , G01N21/64 , G01N21/6486 , G01N2021/6419 , G01N2021/6421
摘要： The present invention provides a method for detecting, and characterizing a microorganism present in a blood culture medium whereby the method may be accomplished utilizing a time-dependent spectroscopic technique to obtain at least two measurements directly of a blood culture medium and correlating said measurements for the detection and characterization of a microorganism, that may be present in the blood culture.
摘要翻译：本发明提供了一种用于检测和表征存在于血液培养基中的微生物的方法，由此可以使用时间依赖性光谱技术来完成该方法，以直接获得血液培养基的至少两次测量，并将所述测量结果与可能存在于血液培养物中的微生物的检测和表征。

3. 发明申请

US20100291669A1 System for rapid identification and/or characterization of a microbial agent in a sample 有权
标题翻译：用于在样品中快速鉴定和/或表征微生物剂的系统
公开(公告)号：US20100291669A1
公开(公告)日：2010-11-18
申请号：US12800388
申请日：2010-05-14
申请人： Ronnie J. Robinson , Mark S. Wilson , Christopher S. Ronsick , John D. Walsh , Jones M. Hyman , Bradford G. Clay
发明人： Ronnie J. Robinson , Mark S. Wilson , Christopher S. Ronsick , John D. Walsh , Jones M. Hyman , Bradford G. Clay
IPC分类号： C12M1/34
CPC分类号： C12Q1/24 , G01N35/0099 , G01N35/1079 , Y10S901/30
摘要： An automated instrument for identification and/or characterization of a microbial agent present in a sample. The instrument includes (a) a sample removal apparatus operative to remove a test sample from a specimen container and add the test sample to a disposable separation device; (b) a separation and concentration apparatus operative on the separation device to separate the microbial agent from other components which may be present in the test sample and concentrate the microbial agent within the separation device; and (c) a identification and/or characterization module interrogating the concentrated microbial agent to identify and/or characterize the microbial agent.
摘要翻译：用于鉴定和/或表征样品中存在的微生物剂的自动化仪器。仪器包括（a）样品去除装置，用于从试样容器中取出测试样品，并将测试样品加入到一次性分离装置中; （b）分离和浓缩装置，其在分离装置上操作以将微生物剂与可能存在于测试样品中的其它组分分离，并将微生物剂浓缩在分离装置内; 和（c）识别和/或表征模块，询问浓缩的微生物剂以鉴定和/或表征微生物剂。

4. 发明申请

US20100288060A1 Device for sampling a specimen container 有权
标题翻译：用于取样样品容器的装置
公开(公告)号：US20100288060A1
公开(公告)日：2010-11-18
申请号：US12800392
申请日：2010-05-14
申请人： Christopher S. Ronsick , Mark S. Wilson , Ronnie J. Robinson , John D. Walsh , Jones M. Hyman
发明人： Christopher S. Ronsick , Mark S. Wilson , Ronnie J. Robinson , John D. Walsh , Jones M. Hyman
IPC分类号： G01N1/12
CPC分类号： C12Q1/24 , G01N35/0099 , G01N35/1079 , Y10S901/30
摘要： A sampling device for a specimen container having a closure sealing the interior of the specimen container from the environment includes a needle, a body coupled to the needle and defining a chamber in fluid communication with the needle, the body further comprising a port forming an opening in the body, the port in fluid communication with the chamber. A multitude of the sampling devices may be stored in a cassette. The sampling devices may include a second chamber for separation and concentration of a microbial agent present in a sample. In this configuration second chamber is connected to the first chamber via a valve or the like.
摘要翻译：用于样本容器的采样装置具有将样本容器的内部与环境密封的封闭件，其包括：针头，与所述针头相连并且限定与所述针流体连通的室，所述主体还包括形成开口在身体中，与腔室流体连通的端口。多个采样装置可以存储在盒中。采样装置可以包括用于分离和浓缩样品中存在的微生物剂的第二室。在该构造中，第二室通过阀等连接到第一室。

5. 发明授权

US07387883B2 Methods for detecting bacterial pathogens 有权
标题翻译：检测细菌病原体的方法
公开(公告)号：US07387883B2
公开(公告)日：2008-06-17
申请号：US11005668
申请日：2004-12-07
申请人： John D. Walsh , Jones M. Hyman
发明人： John D. Walsh , Jones M. Hyman
IPC分类号： C12Q1/14 , C14Q1/04
CPC分类号： G01N33/56938 , C12Q1/14
摘要： The present invention provides for methods for detecting Staphylococcus aureus in a sample. A preferred method includes the steps of: mixing a sample comprising a medium and microorganisms with a first solution in a vessel, the microorganisms suspected of comprising Staphylococcus aureus; separating the microorganisms from the medium and the bulk of the first solution and removing the medium and the bulk of the first solution from the vessel; adding a second solution to the vessel to resuspend the microorganisms; and detecting Staphylococcus aureus in the resulting suspension of step (c) by using an agglutination test.
摘要翻译：本发明提供了在样品中检测金黄色葡萄球菌的方法。优选的方法包括以下步骤：将包含培养基和微生物的样品与容器中的第一溶液混合，所述微生物怀疑包括金黄色葡萄球菌; 从培养基和大部分第一溶液中分离微生物并从容器中除去介质和第一溶液的体积; 向容器中加入第二溶液以重悬微生物; 并通过使用凝集试验在步骤（c）的所得悬浮液中检测金黄色葡萄球菌。

6. 发明授权

US10774300B2 Methods and kits for isolating microorganisms from culture 有权
公开(公告)号：US10774300B2
公开(公告)日：2020-09-15
申请号：US13554704
申请日：2012-07-20
申请人： Jones M. Hyman , John D. Walsh , Ronnie J. Robinson , Christopher Ronsick
发明人： Jones M. Hyman , John D. Walsh , Ronnie J. Robinson , Christopher Ronsick
IPC分类号： C12Q1/689 , C12Q1/6888 , C12M1/00 , C12Q1/04 , C12N1/02 , C12N1/06 , C12Q1/6895 , C12Q1/24
摘要： The present invention is directed to methods and kits for separating, accumulating, characterizing and/or identifying microorganisms known to be present or that may be present in a test sample. The method of the invention comprises optional lysing non-microorganism cells and/or particulates that may be present in a test sample, followed by a subsequent filtration step for isolation and/or accumulation of microorganisms. The kit of the present invention may comprise at least one filter membrane or an integrated filtration and sample transfer device for isolation and/or accumulation of microorganisms.

7. 发明授权

US09822389B2 Method for the characterization of microorganisms on solid or semi-solid media 有权
公开(公告)号：US09822389B2
公开(公告)日：2017-11-21
申请号：US14444708
申请日：2014-07-28
申请人： Jones M. Hyman , John D. Walsh , Thurman C. Thorpe
发明人： Jones M. Hyman , John D. Walsh , Thurman C. Thorpe
IPC分类号： C12Q1/04
CPC分类号： C12Q1/04
摘要： The present invention relates to methods and systems for scanning, detecting, and monitoring microorganisms on solid or semi-solid media using intrinsic fluorescence (IF) measurements. The methods are further directed to detection, characterization and/or identification of microorganisms on a solid or semi-solid media using intrinsic fluorescence (IF) measurements that are characteristic of said microorganisms.

8. 发明授权

US08841118B2 Combined detection instrument for culture specimen containers and instrument for identification and/or characterization of a microbial agent in a sample 有权
标题翻译：用于培养样品容器的组合检测仪器和用于鉴定和/或表征样品中的微生物剂的仪器
公开(公告)号：US08841118B2
公开(公告)日：2014-09-23
申请号：US12800467
申请日：2010-05-14
申请人： Ronnie J. Robinson , Mark S. Wilson , Christopher S. Ronsick , John D. Walsh , Jones M. Hyman , Thurman C. Thorpe , Bradford G. Clay
发明人： Ronnie J. Robinson , Mark S. Wilson , Christopher S. Ronsick , John D. Walsh , Jones M. Hyman , Thurman C. Thorpe , Bradford G. Clay
IPC分类号： C12M1/00 , C12M3/00 , G01N35/00 , C12M1/34 , C12Q1/04 , G01N35/04
CPC分类号： C12Q1/04 , C12M41/36 , C12Q1/02 , G01N35/00603 , G01N35/0099 , G01N35/026 , G01N2035/00148 , G01N2035/0406 , G01N2035/0453 , G01N2035/0465
摘要： A detection instrument determines whether a specimen container (e.g., blood culture bottle) is positive for presence of microbial agent growth therein. When the container is deemed positive it is made available (e.g, transferred or exposed to) to an automated instrument performing identification and/or characterization of the microbial agent. The identification and/or characterization instrument removes a portion of the sample from the specimen container and places it into a disposable separation and concentration device. The microbial agent is concentrated via optional selective lysis of non-microbial agent cellular material which may be present and centrifugation. A reading module reads the concentrated microbial agent using spectroscopic methods, e.g., measurements of intrinsic fluorescence. Such interrogation may occur while the microbial agent remains concentrated in the disposable device.
摘要翻译：检测仪器确定样品容器（例如血培养瓶）是否对其中存在微生物剂生长是阳性的。当容器被认为是正的时，它被提供（例如，转移或暴露于）到执行微生物剂的鉴定和/或表征的自动化仪器。识别和/或表征仪器将样品的一部分从样品容器中取出并将其放入一次性分离和浓缩装置中。微生物剂通过选择性裂解可能存在的和非离子的非微生物剂细胞材料而浓缩。阅读模块使用光谱方法读取浓缩的微生物剂，例如固有荧光的测量。当微生物剂保持集中在一次性装置中时，可能发生这种询问。

9. 发明申请

US20130045532A1 METHODS AND KITS FOR ISOLATING MICROORGANISMS FROM CULTURE 审中-公开
标题翻译：从文化中分离微生物的方法和工具
公开(公告)号：US20130045532A1
公开(公告)日：2013-02-21
申请号：US13554704
申请日：2012-07-20
申请人： Jones M. Hyman , John D. Walsh , Ronnie J. Robinson , Christopher Ronsick
发明人： Jones M. Hyman , John D. Walsh , Ronnie J. Robinson , Christopher Ronsick
IPC分类号： C12M1/26 , C12M1/40
CPC分类号： C12M47/02 , C12N1/02 , C12N1/06 , C12Q1/24
摘要： The present invention is directed to methods and kits for separating, accumulating, characterizing and/or identifying microorganisms known to be present or that may be present in a test sample. The method of the invention comprises optional lysing non-microorganism cells and/or particulates that may be present in a test sample, followed by a subsequent filtration step for isolation and/or accumulation of microorganisms. The kit of the present invention may comprise at least one filter membrane or an integrated filtration and sample transfer device for isolation and/or accumulation of microorganisms.
摘要翻译：本发明涉及用于分离，积累，表征和/或鉴定已知存在或可能存在于测试样品中的微生物的方法和试剂盒。本发明的方法包括任选地裂解可能存在于测试样品中的非微生物细胞和/或颗粒，随后进行用于分离和/或积累微生物的随后的过滤步骤。本发明的试剂盒可以包括用于分离和/或积累微生物的至少一个过滤膜或一体化过滤和样品转移装置。

10. 发明申请

US20110281291A1 Identification and/or characterization of a microbial agent using taxonomic hierarchical classification 有权
标题翻译：使用分类层次分类鉴定和/或表征微生物
公开(公告)号：US20110281291A1
公开(公告)日：2011-11-17
申请号：US12800379
申请日：2010-05-14
申请人： Michael Ullery , Erin Mathias , Jones M. Hyman , John D. Walsh
发明人： Michael Ullery , Erin Mathias , Jones M. Hyman , John D. Walsh
IPC分类号： C12Q1/04 , G01J3/44 , H01J49/26 , G01N33/48
CPC分类号： C12Q1/04 , G01N21/6486 , G06F19/24
摘要： A method for identification and/or characterization of a microbial agent present in a sample includes a step of analytical test data (e.g., obtaining intrinsic fluorescence values over a range of emission wavelengths) from the microbial agent. The analytical test data is transformed thereby minimizing strain to strain variations within an organism group. With the aid of a programmed computer, a multi-level classification algorithm coded as a set of processing instructions operates on the transformed analytic test data. The multiple levels correspond to different levels in a taxonomic hierarchy for microbial agents suspected of being in the sample.
摘要翻译：用于鉴定和/或表征样品中存在的微生物剂的方法包括从微生物剂中分析测试数据（例如，在发射波长范围内获得固有荧光值）的步骤。转化分析试验数据，从而使生物体组内的应变变化最小化。借助编程的计算机，编码为一组处理指令的多级分类算法对转换的分析测试数据进行操作。多个级别对应于涉嫌在样品中的微生物剂的分类层级中的不同水平。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式