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1. 发明申请

WO2004006989A3 URETERAL ACCESS SHEATH 审中-公开
标题翻译：不便之路
公开(公告)号：WO2004006989A3
公开(公告)日：2004-03-25
申请号：PCT/US0322161
申请日：2003-07-15
申请人： APPLIED MED RESOURCES , DULAK GARY R , CLAYMAN RALPH V
发明人： DULAK GARY R , CLAYMAN RALPH V
IPC分类号： A61M20060101 , A61M25/00 , A61M25/06
CPC分类号： A61M25/0662 , A61M25/0009 , A61M25/0017
摘要： A ureteral access sheath (10) adapted for insertion into a urethra includes an elongate tube (14) extending between a proximal end and a distal end. A handle assembly is disposed at the proximal end and includes enlarged portions (18), which inhibit migration of the sheath into the urethra. The enlarged portions are shaped like the bell of a horn with a concave, distally facing outer surface and a convex, proximally-facing inner surface. The inner surface functions as a funnel while the outer surface is sized and configured to receive adjacent fingers of a user's hand held in its natural position. In an associated method, this shape of the handle assembly facilitates maintaining the sheath in a stationary position during insertion and removal of instrumentation. The handle assembly can be movable on the tube to facilitate variation of the sheath link in situ.
摘要翻译：适于插入尿道的输尿管通路护套（10）包括在近端和远端之间延伸的细长管（14）。手柄组件设置在近端处并且包括放大的部分（18），其抑制护套向尿道的迁移。扩大部分的形状类似喇叭的钟形，具有凹面的，面向远端的外表面和凸起的面向近侧的内表面。内表面用作漏斗，而外表面的尺寸和构造适于接纳保持在其自然位置的用户手的相邻手指。在相关联的方法中，手柄组件的这种形状便于在插入和移除仪器时将护套保持在静止位置。手柄组件可以在管上移动以便于原位将护套连接件变化。

2. 发明申请

WO2004064673A3 ARTIFICIAL NUCLEUS PULPOSUS AND METHOD OF INJECTING SAME 审中-公开
标题翻译：人造核素及其注射方法
公开(公告)号：WO2004064673A3
公开(公告)日：2005-03-10
申请号：PCT/US2004001321
申请日：2004-01-16
申请人： PSINERGI CORP , DULAK GARY R , BHALANI ANIL , MOLLOY PAUL A
发明人： DULAK GARY R , BHALANI ANIL , MOLLOY PAUL A
IPC分类号： A61B17/00 , A61F20060101 , A61F2/00 , A61F2/30 , A61F2/44 , A61F2/46 , A61L27/26
CPC分类号： A61F2/4611 , A61B17/00234 , A61F2/441 , A61F2/4601 , A61F2002/30088 , A61F2002/30583 , A61F2002/444 , A61F2002/4635 , A61F2210/008 , A61F2210/0085 , A61L27/26
摘要： An artificial nucleus pulposus implant (102, 104) is injected minimally invasively into the nucleus cavity (51) of the annulus fibrosus (12). A device (70) delivers a phase changing biomaterial in a fluid state (102) to a tissue site. The device (70) comprises a dispenser (72) including a plunger (76), a dispensing actuator (74), and a cartridge (80) insertable into an inlet of the plunger (76) for containing the phase changing biomaterial in a fluid state (102). The biomaterial is permitted to transition from the fluid state (102) to a solid state (104) in-situ after a given condition.
摘要翻译：人造髓核植入物（102,104）被最少侵入地注射到纤维环（12）的细胞腔（51）中。装置（70）将流体状态（102）中的相变生物材料输送到组织部位。装置（70）包括分配器（72），其包括柱塞（76），分配致动器（74）和可插入到柱塞（76）的入口中的筒（80），用于将相变生物材料容纳在流体州（102）。允许生物材料在给定条件之后原位从流体状态（102）转变为固态（104）。

3. 发明申请

WO2003032819A1 LAPAROSCOPIC ILLUMINATION APPARATUS AND METHOD 审中-公开
标题翻译： LAPAROSCOPIC ILLUMINATION装置和方法
公开(公告)号：WO2003032819A1
公开(公告)日：2003-04-24
申请号：PCT/US2001/032393
申请日：2001-10-17
申请人： APPLIED MEDICAL RESOURCES CORPORATION , EWERS, Richard, C. , DULAK, Gary, R. , HILAL, Nabil
发明人： EWERS, Richard, C. , DULAK, Gary, R. , HILAL, Nabil
IPC分类号： A61B1/32
CPC分类号： A61B1/32 , A61B1/00154 , A61B17/3423 , A61B90/30
摘要： An access device (34) particularly adapted for use in laparoscopic surgery facilitates access with instruments, such as the hand (17) of the surgeon (14), across a body wall (21) and into a body cavity (18). The device can be formed of a gel material having properties for forming a zero seal, or an instrument seal with a wide range of instrument diameters. The gel material can be translucent facilitating illumination and visualization of the surgical site through the access device.
摘要翻译：特别适用于腹腔镜手术的进入装置（34）便于使用诸如外科医生（14）的手部（17）的仪器穿过体壁（21）进入体腔（18）。该装置可以由具有用于形成零密封的性质的凝胶材料或具有宽范围的仪器直径的仪器密封件形成。凝胶材料可以是半透明的，便于通过进入装置对外科手术部位的照明和可视化。

4. 发明申请

WO2004075930A2 APPARATUS AND METHOD FOR ILLUMINATING A PERITONEAL CAVITY DURING LAPAROSCOPIC SURGERY 审中-公开
标题翻译：用于在腹腔镜手术期间照射皮质囊的装置和方法
公开(公告)号：WO2004075930A2
公开(公告)日：2004-09-10
申请号：PCT/US2004/005361
申请日：2004-02-24
申请人： APPLIED MEDICAL RESOURCES CORPORATION , DULAK, Gary, R. , HILAL, Nabil
发明人： DULAK, Gary, R. , HILAL, Nabil
IPC分类号： A61L
CPC分类号： A61B17/3423 , A61B17/0293 , A61B17/3431 , A61B90/30 , A61B90/50 , A61B2017/00557 , A61B2017/0084 , A61B2017/00867 , A61B2017/3407 , A61B2017/3486 , A61B2017/3492
摘要： A surgical valve is adapted to access a body cavity through an incision in the body wall. The valve is preferably formed of a gel material which defines a slit through the valve, the slit having properties for forming an instrument seal in the presence of an instrument and a zero seal in the absence of an instrument. The gel material preferably has transparent characteristics facilitating illumination and observation of the body cavity through the valve. Preferred omni-directional light is produced by multiple light sources which can be embedded in the gel of the valve.
摘要翻译：手术阀适于通过体壁中的切口进入体腔。阀优选地由凝胶材料形成，该凝胶材料限定通过阀的狭缝，该狭缝具有用于在仪器存在下形成仪器密封的特性，并且在不存在仪器的情况下为零密封。凝胶材料优选具有透明特性，便于通过阀照射和观察体腔。优选的全向光由可以嵌入阀的凝胶中的多个光源产生。

5. 发明申请

WO2004064673A2 ARTIFICIAL NUCLEUS PULPOSUS AND METHOD OF INJECTING SAME 审中-公开
标题翻译：人造核素及其注射方法
公开(公告)号：WO2004064673A2
公开(公告)日：2004-08-05
申请号：PCT/US2004/001321
申请日：2004-01-16
申请人： PSINERGI CORPORATION , DULAK, Gary, R. , BHALANI, Anil , MOLLOY, Paul, A.
发明人： DULAK, Gary, R. , BHALANI, Anil , MOLLOY, Paul, A.
IPC分类号： A61F
CPC分类号： A61F2/4611 , A61B17/00234 , A61F2/441 , A61F2/4601 , A61F2002/30088 , A61F2002/30583 , A61F2002/444 , A61F2002/4635 , A61F2210/008 , A61F2210/0085 , A61L27/26
摘要： The present invention relates to an artificial nucleus pulposus implant that is injected minimally invasively into the nucleus cavity of the annulus fibrosus to restore the normal anatomical and physiological function of the spine in the affected disc segment. In one aspect of the invention, a device is disclosed for delivering a phase changing biomaterial to a tissue site, the device comprising a dispenser including (i) a plunger having a proximal portion and a distal portion, an inlet end and an outlet end, (ii) a dispensing actuator attached to the proximal portion of the plunger, and (iii) a cartridge adapted to be inserted into the inlet end of the plunger for containing the phase changing biomaterial in a fluid state. The dispenser may be mechanically, pneumatically or hydraulically actuated. The dispenser may further comprise a nozzle attached to the cartridge for dispensing the biomaterial to the tissue site. In another aspect, the device may further comprise a tissue cavity access unit providing a conduit having an inlet end in fluid communication with the nozzle, and an outlet end adapted to deliver the biomaterial to the tissue site. The biomaterial may transition from the fluid state to a solid state after a set amount of time, a temperature change or an exposure to an external stimuli such as radiation, UV light or an electrical stimuli. The cartridge may be a dual-chambered cartridge for storing different fluid biomaterials in the two chambers. In another aspect of the invention, a process for producing the artificial nucleus pulposus implant in the nucleus cavity of the annulus fibrosus is disclosed, the process comprising the steps of (a) obtaining access to the nucleus cavity; (b) injecting the artificial nucleus pulposus into the nucleus cavity; and (c) permitting the biomaterial to transition from a fluid state to a solid state in-situ after a given condition.
摘要翻译：本发明涉及一种人造髓核植入物，其被最小程度地侵入到纤维环的核腔中，以恢复受影响椎间盘段脊柱的正常解剖和生理功能。在本发明的一个方面，公开了一种用于将相变生物材料输送到组织部位的装置，该装置包括分配器，该分配器包括（i）具有近端部分和远端部分的柱塞，入口端和出口端，（ii）附接到柱塞的近端部分的分配致动器，以及（iii）适于插入到柱塞的入口端的筒，用于容纳处于流体状态的相变生物材料。分配器可以是机械的，气动的或液压致动的。分配器还可以包括连接到盒的喷嘴，用于将生物材料分配到组织部位。在另一方面，所述装置还可以包括组织腔进入单元，其提供具有与所述喷嘴流体连通的入口端的导管，以及适于将生物材料输送到组织部位的出口端。生物材料可以在经过一定时间，温度变化或暴露于诸如辐射，紫外光或电刺激的外部刺激之后从流体状态转变为固态。盒可以是用于在两个腔室中存储不同流体生物材料的双腔筒。在本发明的另一方面，公开了一种在纤维环的细胞腔内制备人造髓核植入物的方法，该方法包括以下步骤：（a）获得进入核腔的步骤; （b）将人造髓核注入核腔; 和（c）允许生物材料在给定条件之后从原位流体状态转变为固态。

6. 发明申请

WO2004006989A2 URETERAL ACCESS SHEATH 审中-公开
标题翻译：不便之路
公开(公告)号：WO2004006989A2
公开(公告)日：2004-01-22
申请号：PCT/US2003/022161
申请日：2003-07-15
申请人： APPLIED MEDICAL RESOURCES CORPORATION , DULAK, Gary, R. , CLAYMAN, Ralph, V.
发明人： DULAK, Gary, R. , CLAYMAN, Ralph, V.
IPC分类号： A61M
CPC分类号： A61M25/0662 , A61M25/0009 , A61M25/0017
摘要： A ureteral access sheath adapted for insertion into a urethra includes an elongate tube extending between a proximal end and a distal end. A handle assembly is disposed at the proximal end and includes enlarged portions which inhibit migration of the sheath into the urethra. The enlarged portions are shaped like the bell of a horn with a concave, distally-facing outer surface and a convex, proximally-facing inner surface. The inner surface functions as a funnel while the outer surface is sized and configured to receive adjacent fingers of a user's hand held in its natural position. In an associated method, this shape of the handle assembly facilitates maintaining the sheath in a stationary position during insertion and removal of instrumentation. The handle assembly can be movable on the tube to facilitate variation of the sheath link in situ .
摘要翻译：适于插入尿道的输尿管通路护套包括在近端和远端之间延伸的细长管。手柄组件设置在近端处，并且包括抑制鞘进入尿道的迁移的扩大部分。扩大部分的形状像喇叭的钟形，具有凹面的朝向外侧的外表面和朝向内侧的凸面的内表面。内表面用作漏斗，而外表面的尺寸和构造适于接纳保持在其自然位置的用户手的相邻手指。在相关联的方法中，手柄组件的这种形状便于在插入和移除仪器时将护套保持在静止位置。手柄组件可以在管上移动以便于原位将护套连接件变化。

7. 发明申请

WO2004075741A2 WOUND RETRACTOR FOR USE IN HAND ASSISTED LAPAROSCOPIC SURGERY 审中-公开
标题翻译：伤口牵引器用于手部辅助腹腔镜手术
公开(公告)号：WO2004075741A2
公开(公告)日：2004-09-10
申请号：PCT/US2004/005487
申请日：2004-02-25
申请人： APPLIED MEDICAL RESOURCES CORPORATION , PINGLETON, Edward, D. , BRUSTAD, John , EWERS, Richard , HILAL, Nabil , ADLPARVAR, Payam , TAYLOR, Scott, V. , DULAK, Gary, R. , DUNN, Michael, J. , MORALES, Norman, L. , HART, Charles, C. , BOWES, Robert, R., II
发明人： PINGLETON, Edward, D. , BRUSTAD, John , EWERS, Richard , HILAL, Nabil , ADLPARVAR, Payam , TAYLOR, Scott, V. , DULAK, Gary, R. , DUNN, Michael, J. , MORALES, Norman, L. , HART, Charles, C. , BOWES, Robert, R., II
IPC分类号： A61B1/32
CPC分类号： A61B17/3423 , A61B17/0293 , A61B17/3431 , A61B90/50 , A61B2017/00557 , A61B2017/0084 , A61B2017/00867 , A61B2017/3407 , A61B2017/3441 , A61B2017/3486 , A61B2017/3492
摘要： A surgical retractor (10) is adapted for use in opening an incision (12) in a body wall (14) to facilitate access into a body cavity. The retractor includes an interior anchor (16) that is disposed interiorly of the body wall and an exterior tensioning device (56) that is disposed exteriorly of the body wall. At least one tension element (21) is coupled to the interior anchor and adapted to pass through the incision to engage the exterior tensioning device. Engaging elements (59, 62) are provided on the exterior tensioning device to engage the tension element and to maintain a tensile force on the tension element as it passes through the incision. Multiple concentric rings can also be used to maintain a tensile force on the tension element.
摘要翻译：手术牵开器（10）适于用于打开体壁（14）中的切口（12）以便于进入体腔。牵开器包括布置在体壁内部的内锚（16）和布置在体壁外部的外部张紧装置（56）。至少一个张紧元件（21）联接到内部锚固件并适于穿过切口以接合外部张紧装置。接合元件（59,62）设置在外部张紧装置上以接合张紧元件并且在张紧元件穿过切口时保持张紧元件上的张力。也可以使用多个同心环来保持拉力元件上的张力。

8. 发明申请

WO03034908A3 SEALED SURGICAL ACCESS DEVICE 审中-公开
标题翻译：密封式手术通路装置
公开(公告)号：WO03034908A3
公开(公告)日：2003-06-05
申请号：PCT/US0150160
申请日：2001-10-20
申请人： APPLIED MED RESOURCES , EWERS RICHARD C , BRUSTAD JOHN R , PINGLETON EDWARD D , HILAL NABIL , ADLPARVAR PAYAM , TAYLOR SCOTT , DULAK GARY R , DUNN MICHAEL J , MORALES NORMAN , HART CHARLES C , BOWES II ROBERT R
发明人： EWERS RICHARD C , BRUSTAD JOHN R , PINGLETON EDWARD D , HILAL NABIL , ADLPARVAR PAYAM , TAYLOR SCOTT , DULAK GARY R , DUNN MICHAEL J , MORALES NORMAN , HART CHARLES C , BOWES II ROBERT R
IPC分类号： A61B1/32 , A61B17/00 , A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/3423 , A61B17/0293 , A61B17/3462 , A61B17/3498 , A61B90/50 , A61B2017/00265 , A61B2017/3405 , A61B2017/3482 , A61B2017/3484 , A61B2017/3486 , A61B2017/3492
摘要： A surgical device (50) is adapted to facilitate access through an incision (100) in a body wall (18) having an inner surface and an outer surface, and into a body cavity of a patinet. The device includes (55) and second (65) retention members adapted to be disposed in proximity to the outer surface and the inner surface of the body wall, respectively. A membrane (75) extending between the two retention members form a throat (90) which is adapted to extend through the incision (100) and form a first funnel extending from the first retention member (55) into the throat (90), and a second funnel extending from the second retention member (65) into the throat (90). The throat of the membrane has characteristics for forming an instrument seal in the presence of an instrument and a zero seal in the absence of an instrument. The first retention member (55) may include a ring with either a fixed or variable diameter.
摘要翻译：手术装置（50）适于促进通过具有内表面和外表面的体壁（18）中的切口（100）进入盆腔的体腔。该装置包括适于分别设置在体壁的外表面和内表面附近的（55）和第二（65）保持构件。在两个保持构件之间延伸的膜（75）形成适于延伸穿过切口（100）并形成从第一保持构件（55）延伸到喉部（90）中的第一漏斗的喉部（90），以及从第二保持构件（65）延伸到喉部（90）中的第二漏斗。膜的喉部具有用于在存在仪器的情况下形成仪器密封并且在没有仪器的情况下形成零密封的特征。第一保持构件（55）可以包括具有固定或可变直径的环。

9. 发明申请

WO2003034908A2 SEALED SURGICAL ACCESS DEVICE 审中-公开
标题翻译：密封外科手术器械
公开(公告)号：WO2003034908A2
公开(公告)日：2003-05-01
申请号：PCT/US2001/050160
申请日：2001-10-20
申请人： APPLIED MEDICAL RESOURCES CORPORATION , EWERS, Richard, C. , BRUSTAD, John, R. , PINGLETON, Edward, D. , HILAL, Nabil , ADLPARVAR, Payam , TAYLOR, Scott , DULAK, Gary, R. , DUNN, Michael, J. , MORALES, Norman , HART, Charles, C. , BOWES II, Robert, R.
发明人： EWERS, Richard, C. , BRUSTAD, John, R. , PINGLETON, Edward, D. , HILAL, Nabil , ADLPARVAR, Payam , TAYLOR, Scott , DULAK, Gary, R. , DUNN, Michael, J. , MORALES, Norman , HART, Charles, C. , BOWES II, Robert, R.
IPC分类号： A61B1/32
CPC分类号： A61B17/3423 , A61B17/0293 , A61B17/3462 , A61B17/3498 , A61B90/50 , A61B2017/00265 , A61B2017/3405 , A61B2017/3482 , A61B2017/3484 , A61B2017/3486 , A61B2017/3492
摘要： A surgical access device is adapted to facilitate access through an incision in a body wall having an inner surface and an outer surface, and into a body cavity of a patient. The device includes first and second retention members adapted to be disposed in proximity to the outer surface and the inner surface of the body wall, respectively. A membrane extending between the two retention members forms a throat which is adapted to extend through the incision and form a first funnel extending from the first retention member into the throat, and a second funnel extending from the second retention member into the throat. The throat of the membrane has characteristics for forming an instrument seal in the presence of an instrument and a zero seal in the absence of an instrument. The first retention member may include a ring with either a fixed or variable diameter. The ring can be formed in first and second sections, each having two ends. Couplings can be disposed between the ends to accommodate variations in the size of the first retention member. The first retention member can also be formed as an inflatable toroid, a self-expanding foam, or a circumferential spring. A plurality of inflatable chambers can also provide the surgical access device with a working channel adapted for disposition across the body wall. A first retention member with a plurality of retention stations functions with a plurality of tethers connected to the membrane to change the shape of the membrane and the working channel. A stabilizing platform can be used to support the access device generally independent of any movement of the body wall.
摘要翻译：手术装置（50）适于便于通过具有内表面和外表面的体壁（18）中的切口（100）进入，并进入立管的体腔。该装置包括适于分别设置在本体壁的外表面和内表面附近的（55）和第二（65）保持构件。在两个保持构件之间延伸的膜（75）形成适于延伸穿过切口（100）并且形成从第一保持构件（55）延伸到喉部（90）中的第一漏斗的喉部（90），以及从第二保持构件（65）延伸到喉部（90）中的第二漏斗。膜的喉部具有在没有仪器的情况下在仪器存在下形成仪器密封件的特性和零密封。第一保持构件（55）可以包括具有固定或可变直径的环。

10. 发明申请

WO0234108A3 SURGICAL ACCESS APPARATUS AND METHOD 审中-公开
标题翻译：手术通路装置和方法
公开(公告)号：WO0234108A3
公开(公告)日：2002-12-27
申请号：PCT/US0129682
申请日：2001-09-21
申请人： APPLIED MED RESOURCES , EWERS RICHARD C , BRUSTAD JOHN , PINGLETON EDWARD D , HILAL NABIL , DULAK GARY R , ADLPARVAR PAYAM , BOWES ROBERT R
发明人： EWERS RICHARD C , BRUSTAD JOHN , PINGLETON EDWARD D , HILAL NABIL , DULAK GARY R , ADLPARVAR PAYAM , BOWES ROBERT R
IPC分类号： A61B19/00 , A61B17/00 , A61B17/02 , A61B17/34 , A61B1/32
CPC分类号： A61B17/3423 , A61B17/0218 , A61B17/0293 , A61B17/3474 , A61B17/3498 , A61B2017/00265 , A61B2017/00526 , A61B2017/3419 , A61B2017/3445 , A61B2017/3492 , A61M13/003
摘要： A surgical access device (34) includes a single valve (35) that forms a seal with the body wall (21) and provides an access channel (32) into a body cavity (18). The valve (35) has properties for creating a zero seal in the absence of an instrument, an instrument seal in the presence of instruments, or a hand port to provide access into the cavity (18). The valve can include a gel, preferably an ultragel comprised of an elastomer and an oil providing elongation greater than 1000 percent and durometer less than 5 Shore A. A method for making the surgical access device includes the combining of a gelling agent with an oil, preferably by molding. A method for use includes steps for creating an opening with the instrument. The valve and method are particularly adapted for laparoscopic surgery wherein the abdominal cavity is insufflated with a gas.
摘要翻译：外科进入装置（34）包括与主体壁（21）形成密封并将进入通道（32）提供到体腔（18）中的单个阀（35）。阀（35）具有用于在没有器械的情况下产生零密封的特性，在器械存在的情况下的器械密封件或提供通向腔体（18）的手端口的特征。所述瓣膜可以包括凝胶，优选为由弹性体和油提供的超凝胶，所述超凝胶提供大于1000％的伸长率和小于5肖氏A的硬度。制造外科手术进入装置的方法包括将胶凝剂与油，优选通过模制。使用方法包括用仪器创建开口的步骤。该瓣膜和方法特别适用于其中腹腔注入气体的腹腔镜手术。

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