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1. 发明申请

WO0234108A3 SURGICAL ACCESS APPARATUS AND METHOD 审中-公开
标题翻译：手术通路装置和方法
公开(公告)号：WO0234108A3
公开(公告)日：2002-12-27
申请号：PCT/US0129682
申请日：2001-09-21
申请人： APPLIED MED RESOURCES , EWERS RICHARD C , BRUSTAD JOHN , PINGLETON EDWARD D , HILAL NABIL , DULAK GARY R , ADLPARVAR PAYAM , BOWES ROBERT R
发明人： EWERS RICHARD C , BRUSTAD JOHN , PINGLETON EDWARD D , HILAL NABIL , DULAK GARY R , ADLPARVAR PAYAM , BOWES ROBERT R
IPC分类号： A61B19/00 , A61B17/00 , A61B17/02 , A61B17/34 , A61B1/32
CPC分类号： A61B17/3423 , A61B17/0218 , A61B17/0293 , A61B17/3474 , A61B17/3498 , A61B2017/00265 , A61B2017/00526 , A61B2017/3419 , A61B2017/3445 , A61B2017/3492 , A61M13/003
摘要： A surgical access device (34) includes a single valve (35) that forms a seal with the body wall (21) and provides an access channel (32) into a body cavity (18). The valve (35) has properties for creating a zero seal in the absence of an instrument, an instrument seal in the presence of instruments, or a hand port to provide access into the cavity (18). The valve can include a gel, preferably an ultragel comprised of an elastomer and an oil providing elongation greater than 1000 percent and durometer less than 5 Shore A. A method for making the surgical access device includes the combining of a gelling agent with an oil, preferably by molding. A method for use includes steps for creating an opening with the instrument. The valve and method are particularly adapted for laparoscopic surgery wherein the abdominal cavity is insufflated with a gas.
摘要翻译：外科进入装置（34）包括与主体壁（21）形成密封并将进入通道（32）提供到体腔（18）中的单个阀（35）。阀（35）具有用于在没有器械的情况下产生零密封的特性，在器械存在的情况下的器械密封件或提供通向腔体（18）的手端口的特征。所述瓣膜可以包括凝胶，优选为由弹性体和油提供的超凝胶，所述超凝胶提供大于1000％的伸长率和小于5肖氏A的硬度。制造外科手术进入装置的方法包括将胶凝剂与油，优选通过模制。使用方法包括用仪器创建开口的步骤。该瓣膜和方法特别适用于其中腹腔注入气体的腹腔镜手术。

2. 发明申请

WO03034908A3 SEALED SURGICAL ACCESS DEVICE 审中-公开
标题翻译：密封式手术通路装置
公开(公告)号：WO03034908A3
公开(公告)日：2003-06-05
申请号：PCT/US0150160
申请日：2001-10-20
申请人： APPLIED MED RESOURCES , EWERS RICHARD C , BRUSTAD JOHN R , PINGLETON EDWARD D , HILAL NABIL , ADLPARVAR PAYAM , TAYLOR SCOTT , DULAK GARY R , DUNN MICHAEL J , MORALES NORMAN , HART CHARLES C , BOWES II ROBERT R
发明人： EWERS RICHARD C , BRUSTAD JOHN R , PINGLETON EDWARD D , HILAL NABIL , ADLPARVAR PAYAM , TAYLOR SCOTT , DULAK GARY R , DUNN MICHAEL J , MORALES NORMAN , HART CHARLES C , BOWES II ROBERT R
IPC分类号： A61B1/32 , A61B17/00 , A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/3423 , A61B17/0293 , A61B17/3462 , A61B17/3498 , A61B90/50 , A61B2017/00265 , A61B2017/3405 , A61B2017/3482 , A61B2017/3484 , A61B2017/3486 , A61B2017/3492
摘要： A surgical device (50) is adapted to facilitate access through an incision (100) in a body wall (18) having an inner surface and an outer surface, and into a body cavity of a patinet. The device includes (55) and second (65) retention members adapted to be disposed in proximity to the outer surface and the inner surface of the body wall, respectively. A membrane (75) extending between the two retention members form a throat (90) which is adapted to extend through the incision (100) and form a first funnel extending from the first retention member (55) into the throat (90), and a second funnel extending from the second retention member (65) into the throat (90). The throat of the membrane has characteristics for forming an instrument seal in the presence of an instrument and a zero seal in the absence of an instrument. The first retention member (55) may include a ring with either a fixed or variable diameter.
摘要翻译：手术装置（50）适于促进通过具有内表面和外表面的体壁（18）中的切口（100）进入盆腔的体腔。该装置包括适于分别设置在体壁的外表面和内表面附近的（55）和第二（65）保持构件。在两个保持构件之间延伸的膜（75）形成适于延伸穿过切口（100）并形成从第一保持构件（55）延伸到喉部（90）中的第一漏斗的喉部（90），以及从第二保持构件（65）延伸到喉部（90）中的第二漏斗。膜的喉部具有用于在存在仪器的情况下形成仪器密封并且在没有仪器的情况下形成零密封的特征。第一保持构件（55）可以包括具有固定或可变直径的环。

3. 发明申请

WO2004075741A3 WOUND RETRACTOR FOR USE IN HAND ASSISTED LAPAROSCOPIC SURGERY 审中-公开
标题翻译：用于手部辅助手术的绕线器
公开(公告)号：WO2004075741A3
公开(公告)日：2004-10-14
申请号：PCT/US2004005487
申请日：2004-02-25
申请人： APPLIED MED RESOURCES , BRUSTAD JOHN , EWERS RICHARD , PINGLETON EDWARD D , HILAL NABIL , ADLPARVAR PAYAM , TAYLOR SCOTT V , DULAK GARY R , DUNN MICHAEL J , MORALES NORMAN L , HART CHARLES C , BOWES ROBERT R II
发明人： BRUSTAD JOHN , EWERS RICHARD , PINGLETON EDWARD D , HILAL NABIL , ADLPARVAR PAYAM , TAYLOR SCOTT V , DULAK GARY R , DUNN MICHAEL J , MORALES NORMAN L , HART CHARLES C , BOWES ROBERT R II
IPC分类号： A61B20060101 , A61B1/32 , A61B17/00 , A61B17/34 , A61B19/00 , A61L20060101
CPC分类号： A61B17/3423 , A61B17/0293 , A61B17/3431 , A61B90/50 , A61B2017/00557 , A61B2017/0084 , A61B2017/00867 , A61B2017/3407 , A61B2017/3441 , A61B2017/3486 , A61B2017/3492
摘要： A surgical retractor (10) is adapted for use in opening an incision (12) in a body wall (14) to facilitate access into a body cavity. The retractor includes an interior anchor (16) that is disposed interiorly of the body wall and an exterior tensioning device (56) that is disposed exteriorly of the body wall. At least one tension element (21) is coupled to the interior anchor and adapted to pass through the incision to engage the exterior tensioning device. Engaging elements (59, 62) are provided on the exterior tensioning device to engage the tension element and to maintain a tensile force on the tension element as it passes through the incision. Multiple concentric rings can also be used to maintain a tensile force on the tension element.
摘要翻译：手术牵开器（10）适于用于打开体壁（14）中的切口（12），以便于进入体腔。牵开器包括设置在体壁内部的内部锚固件（16）和布置在体壁外部的外部张紧装置（56）。至少一个张力元件（21）联接到内部锚固件并且适于穿过切口以接合外部张紧装置。接合元件（59,62）设置在外部张紧装置上以接合张力元件并且当张紧元件通过切口时在张力元件上保持张力。也可以使用多个同心环来保持张力元件上的张力。

4. 发明申请

WO2004075930A3 APPARATUS AND METHOD FOR ILLUMINATING A PERITONEAL CAVITY DURING LAPAROSCOPIC SURGERY 审中-公开
标题翻译：用于在腹腔镜手术期间照射腹腔的装置和方法
公开(公告)号：WO2004075930A3
公开(公告)日：2005-03-24
申请号：PCT/US2004005361
申请日：2004-02-24
申请人： APPLIED MED RESOURCES , DULAK GARY R , HILAL NABIL
发明人： DULAK GARY R , HILAL NABIL
IPC分类号： A61B20060101 , A61B1/32 , A61B17/00 , A61B17/34 , A61B19/00 , A61L20060101
CPC分类号： A61B17/3423 , A61B17/0293 , A61B17/3431 , A61B90/30 , A61B90/50 , A61B2017/00557 , A61B2017/0084 , A61B2017/00867 , A61B2017/3407 , A61B2017/3486 , A61B2017/3492
摘要： A surgical valve (12) is adapted to access a body cavity (18) through an incision (16) in the body wall (14). The valve (12) is preferably formed of a gel material which defines a slit (21) through the valve (12), the slit (21) having properties for forming an instrument seal in the presence of an instrument and a zero seal in the absence of an instrument. The gel material preferably has transparent characteristics facilitating illumination and observation of the body cavity (18) through valve (12). Preferred omni-directional light is produced by multiple light sources (25) which can be embedded in the gel of the valve (12).
摘要翻译：手术阀（12）适于通过体壁（14）中的切口（16）进入体腔（18）。阀（12）优选由凝胶材料形成，该凝胶材料通过阀（12）限定狭缝（21），狭缝（21）具有用于在仪器存在下形成仪器密封的特性，没有乐器。凝胶材料优选具有便于通过阀（12）照射和观察体腔（18）的透明特性。优选的全向光由可以嵌入阀（12）的凝胶中的多个光源（25）产生。

5. 发明申请

WO2004006989A3 URETERAL ACCESS SHEATH 审中-公开
标题翻译：不便之路
公开(公告)号：WO2004006989A3
公开(公告)日：2004-03-25
申请号：PCT/US0322161
申请日：2003-07-15
申请人： APPLIED MED RESOURCES , DULAK GARY R , CLAYMAN RALPH V
发明人： DULAK GARY R , CLAYMAN RALPH V
IPC分类号： A61M20060101 , A61M25/00 , A61M25/06
CPC分类号： A61M25/0662 , A61M25/0009 , A61M25/0017
摘要： A ureteral access sheath (10) adapted for insertion into a urethra includes an elongate tube (14) extending between a proximal end and a distal end. A handle assembly is disposed at the proximal end and includes enlarged portions (18), which inhibit migration of the sheath into the urethra. The enlarged portions are shaped like the bell of a horn with a concave, distally facing outer surface and a convex, proximally-facing inner surface. The inner surface functions as a funnel while the outer surface is sized and configured to receive adjacent fingers of a user's hand held in its natural position. In an associated method, this shape of the handle assembly facilitates maintaining the sheath in a stationary position during insertion and removal of instrumentation. The handle assembly can be movable on the tube to facilitate variation of the sheath link in situ.
摘要翻译：适于插入尿道的输尿管通路护套（10）包括在近端和远端之间延伸的细长管（14）。手柄组件设置在近端处并且包括放大的部分（18），其抑制护套向尿道的迁移。扩大部分的形状类似喇叭的钟形，具有凹面的，面向远端的外表面和凸起的面向近侧的内表面。内表面用作漏斗，而外表面的尺寸和构造适于接纳保持在其自然位置的用户手的相邻手指。在相关联的方法中，手柄组件的这种形状便于在插入和移除仪器时将护套保持在静止位置。手柄组件可以在管上移动以便于原位将护套连接件变化。

6. 发明申请

WO2004064673A3 ARTIFICIAL NUCLEUS PULPOSUS AND METHOD OF INJECTING SAME 审中-公开
标题翻译：人造核素及其注射方法
公开(公告)号：WO2004064673A3
公开(公告)日：2005-03-10
申请号：PCT/US2004001321
申请日：2004-01-16
申请人： PSINERGI CORP , DULAK GARY R , BHALANI ANIL , MOLLOY PAUL A
发明人： DULAK GARY R , BHALANI ANIL , MOLLOY PAUL A
IPC分类号： A61B17/00 , A61F20060101 , A61F2/00 , A61F2/30 , A61F2/44 , A61F2/46 , A61L27/26
CPC分类号： A61F2/4611 , A61B17/00234 , A61F2/441 , A61F2/4601 , A61F2002/30088 , A61F2002/30583 , A61F2002/444 , A61F2002/4635 , A61F2210/008 , A61F2210/0085 , A61L27/26
摘要： An artificial nucleus pulposus implant (102, 104) is injected minimally invasively into the nucleus cavity (51) of the annulus fibrosus (12). A device (70) delivers a phase changing biomaterial in a fluid state (102) to a tissue site. The device (70) comprises a dispenser (72) including a plunger (76), a dispensing actuator (74), and a cartridge (80) insertable into an inlet of the plunger (76) for containing the phase changing biomaterial in a fluid state (102). The biomaterial is permitted to transition from the fluid state (102) to a solid state (104) in-situ after a given condition.
摘要翻译：人造髓核植入物（102,104）被最少侵入地注射到纤维环（12）的细胞腔（51）中。装置（70）将流体状态（102）中的相变生物材料输送到组织部位。装置（70）包括分配器（72），其包括柱塞（76），分配致动器（74）和可插入到柱塞（76）的入口中的筒（80），用于将相变生物材料容纳在流体州（102）。允许生物材料在给定条件之后原位从流体状态（102）转变为固态（104）。

7. 发明申请

WO2004064673A9 ARTIFICIAL NUCLEUS PULPOSUS AND METHOD OF INJECTING SAME 审中-公开
标题翻译：人造髓核及其注射方法
公开(公告)号：WO2004064673A9
公开(公告)日：2004-09-10
申请号：PCT/US2004001321
申请日：2004-01-16
申请人： PSINERGI CORP , DULAK GARY R , BHALANI ANIL , MOLLOY PAUL A
发明人： DULAK GARY R , BHALANI ANIL , MOLLOY PAUL A
IPC分类号： A61B17/00 , A61F20060101 , A61F2/00 , A61F2/30 , A61F2/44 , A61F2/46 , A61L27/26 , A61F
CPC分类号： A61F2/4611 , A61B17/00234 , A61F2/441 , A61F2/4601 , A61F2002/30088 , A61F2002/30583 , A61F2002/444 , A61F2002/4635 , A61F2210/008 , A61F2210/0085 , A61L27/26
摘要： The present invention relates to an artificial nucleus pulposus implant that is injected minimally invasively into the nucleus cavity of the annulus fibrosus to restore the normal anatomical and physiological function of the spine in the affected disc segment. In one aspect of the invention, a device is disclosed for delivering a phase changing biomaterial to a tissue site, the device comprising a dispenser including (i) a plunger having a proximal portion and a distal portion, an inlet end and an outlet end, (ii) a dispensing actuator attached to the proximal portion of the plunger, and (iii) a cartridge adapted to be inserted into the inlet end of the plunger for containing the phase changing biomaterial in a fluid state. The dispenser may be mechanically, pneumatically or hydraulically actuated. The dispenser may further comprise a nozzle attached to the cartridge for dispensing the biomaterial to the tissue site. In another aspect, the device may further comprise a tissue cavity access unit providing a conduit having an inlet end in fluid communication with the nozzle, and an outlet end adapted to deliver the biomaterial to the tissue site. The biomaterial may transition from the fluid state to a solid state after a set amount of time, a temperature change or an exposure to an external stimuli such as radiation, UV light or an electrical stimuli. The cartridge may be a dual-chambered cartridge for storing different fluid biomaterials in the two chambers. In another aspect of the invention, a process for producing the artificial nucleus pulposus implant in the nucleus cavity of the annulus fibrosus is disclosed, the process comprising the steps of (a) obtaining access to the nucleus cavity; (b) injecting the artificial nucleus pulposus into the nucleus cavity; and (c) permitting the biomaterial to transition from a fluid state to a solid state in-situ after a given condition.
摘要翻译：本发明涉及人造髓核植入物，其被微创地侵入到纤维环的髓核腔中，以恢复受影响的椎间盘节段中脊柱的正常解剖和生理功能。在本发明的一个方面中，公开了一种用于将相变生物材料递送至组织部位的装置，该装置包括分配器，该分配器包括（i）具有近端部分和远端部分，入口端和出口端的柱塞，（ii）连接到柱塞的近侧部分的分配致动器，以及（iii）适于插入柱塞的入口端以用于容纳处于流体状态的相变生物材料的筒。分配器可以机械地，气动地或液压地致动。分配器可进一步包括附接到药筒的喷嘴，用于将生物材料分配到组织部位。在另一方面，该装置可进一步包括组织空腔通路单元，其提供具有与喷嘴流体连通的入口端和适于将生物材料递送至组织部位的出口端的导管。在设定的时间量，温度变化或暴露于诸如辐射，UV光或电刺激的外部刺激之后，生物材料可以从流体状态转变为固态。盒可以是用于在两个腔室中存储不同的流体生物材料的双腔盒。在本发明的另一方面中，公开了一种用于在纤维环的髓核中产生人造髓核植入物的方法，该方法包括以下步骤：（a）进入髓核腔; （b）将人造髓核注入髓核腔; 和（c）允许生物材料在给定条件后原位从流体状态过渡到固态。

8. 发明公开

EP1326524A4 SURGICAL ACCESS APPARATUS AND METHOD 有权
标题翻译：外科手术进入装置和方法
公开(公告)号：EP1326524A4
公开(公告)日：2007-08-15
申请号：EP01973379
申请日：2001-09-21
申请人： APPLIED MED RESOURCES
发明人： EWERS RICHARD C , BRUSTAD JOHN , PINGLETON EDWARD D , HILAL NABIL , DULAK GARY R , ADLPARVAR PAYAM , BOWES ROBERT R
IPC分类号： A61B19/00 , A61B17/00 , A61B17/02 , A61B17/34 , A61B1/32
CPC分类号： A61B17/3423 , A61B17/0218 , A61B17/0293 , A61B17/3474 , A61B17/3498 , A61B2017/00265 , A61B2017/00526 , A61B2017/3419 , A61B2017/3445 , A61B2017/3492 , A61M13/003
摘要： A surgical access device (34) includes a single valve (35) that forms a seal with the body wall (21) and provides an access channel (32) into a body cavity (18). The valve (35) has properties for creating a zero seal in the absence of an instrument, an instrument seal in the presence of instruments, or a hand port to provide access into the cavity (18). The valve can include a gel, preferably an ultragel comprised of an elastomer and an oil providing elongation greater than 1000 percent and durometer less than 5 Shore A. A method for making the surgical access device includes the combining of a gelling agent with an oil, preferably by molding. A method for use includes steps for creating an opening with the instrument. The valve and method are particularly adapted for laparoscopic surgery wherein the abdominal cavity is insufflated with a gas.

9. 发明公开

EP1441648A4 WOUND RETRACTION APPARATUS AND METHOD 有权转让
标题翻译： WUNDRETRAKTIONSVORRICHTUNG UND VERFAHREN
公开(公告)号：EP1441648A4
公开(公告)日：2008-04-09
申请号：EP01985170
申请日：2001-10-20
申请人： APPLIED MED RESOURCES
发明人： EWERS RICHARD C , BRUSTAD JOHN R , PINGLETON EDWARD D , HILAL NABIL , ADLPARVAR PAYAM , TAYLOR SCOTT , DULAK GARY R , DUNN MICHAEL J , MORALES NORMAN , HART CHARLES C , BOWES ROBERT R II
IPC分类号： A61B17/00 , A61B17/02 , A61B17/34
CPC分类号： A61B17/0293 , A61B17/3423 , A61B17/3431 , A61B2017/00407 , A61B2017/00544 , A61B2017/00557 , A61B2017/3419
摘要： A surgical wound retractor (12) is adapted to dilate a wound (10) stretchable to a desired diameter, the retractor includes a first ring (14) having a diameter greater than that desired for the wound and being adapted for disposition interiorly of the wound. A second ring (16) has a diameter greater than that desired for the wound and is adapted for disposition exteriorly of the wound. A plurality of retraction elements (36) are disposed in a generally cylindrical relationship to each other, between the first ring (14) and the second ring (16). These elements extend through the wound to exert a radial retraction force on the wound which is dependent on the distance separating the first ring and the second ring. Retraction elements, both distensible and non-distensible are contemplated with appropriate attachment means at the rings to provide for variations in the retraction force. Rings can also be made inflatable or self-expanding to vary the retraction force. An associated method includes the step of rolling the second ring circumferentially of the third ring (83) to form the circumferential retainer.
摘要翻译：外科伤口牵开器（12）适于扩张可拉伸至期望直径的伤口（10），牵开器包括第一环（14），该第一环的直径大于伤口所需的直径并且适于在伤口内部布置。第二环（16）的直径大于伤口所需的直径并且适于在伤口外部布置。多个回缩元件（36）在第一环（14）和第二环（16）之间以大致圆柱形的关系设置。这些元件延伸穿过伤口以在伤口上施加径向回缩力，这取决于分隔第一环和第二环的距离。预期收缩元件和可扩张元件均具有在环上的适当附接装置以提供收缩力的变化。戒指也可以做成可充气或自我膨胀来改变收缩力。相关联的方法包括沿第三环（83）的周向滚动第二环以形成周向保持器的步骤。

10. 发明专利

CA2422782A1 SURGICAL ACCESS APPARATUS AND METHOD 未知
公开(公告)号：CA2422782A1
公开(公告)日：2002-05-02
申请号：CA2422782
申请日：2001-09-21
申请人： APPLIED MED RESOURCES
发明人： PINGLETON EDWARD D , ADLPARVAR PAYAM , EWERS RICHARD C , BOWES ROBERT R , DULAK GARY R , HILAL NABIL , BRUSTAD JOHN
IPC分类号： A61B19/00 , A61B17/00 , A61B17/02 , A61B17/34 , A61B1/32
摘要： A surgical access device (34) includes a single valve (35) that forms a seal with the body wall (21) and provides an access channel (32) into a body cavi ty (18). The valve (35) has properties for creating a zero seal in the absence of an instrument, an instrument seal in the presence of instruments, or a hand port to provide access into the cavity (18). The valve can include a gel, preferably an ultragel comprised of an elastomer and an oil providing elongation greater than 1000 percent and durometer less than 5 Shore A. A method for making the surgical access device includes the combining of a gelling agent with an oil, preferably by molding. A method for use includes steps for creating an opening with the instrument. The valve and method are particularly adapted for laparoscopic surgery wherein the abdominal cavity i s insufflated with a gas.

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