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    • 6. 发明申请
    • EXTRA-SYSTOLIC STIMULATION THERAPY DELIVERY AND SENSING VIA DIFFERENT ELECTRODE SETS
    • 超声波刺激治疗通过不同的电极组传递和感测
    • WO2005035053A1
    • 2005-04-21
    • PCT/US2004/033258
    • 2004-10-07
    • MEDTRONIC, INC.ZILLMER, Glenn, C.DENO, Curtis, D.SHETH, Nirav, Vijay
    • ZILLMER, Glenn, C.DENO, Curtis, D.SHETH, Nirav, Vijay
    • A61N1/365
    • A61N1/365A61N1/3622
    • Techniques for delivering ESS to a heart of a patient are disclosed. An implantable medical device delivers ESS stimulation, and in some embodiments pacing stimulation, to a chamber of the heart via a first electrode set. The implantable medical device senses electrical activity within the chamber via a second set of electrodes. In some embodiments, the implantable medical device is able to apply a shorter blanking interval than is typical in the pacing art to a sense amplifier coupled to the second set of electrodes, allowing the implantable medical device to better detect arrhythmias and evoked responses. A variety of electrodes may be used in conjunction with the present invention; including without limitation, tip, ring, coil, can-based, endocardial, epicardial, pericardial, cardiac vein-based, subcutaneous, and/or surface electrodes.
    • 公开了将ESS递送到患者心脏的技术。 可植入医疗装置通过第一电极组将ESS刺激,并且在一些实施例中将起搏刺激提供给心脏室。 可植入医疗装置经由第二组电极感测室内的电活动。 在一些实施例中,可植入医疗装置能够将比起搏技术中典型的更短的消隐间隔应用于耦合到第二组电极的感测放大器,从而允许可植入医疗装置更好地检测心律失常和诱发反应。 可以结合本发明使用各种电极; 包括但不限于尖端,环形,线圈,罐基,心内膜,心外膜,心包,心静脉,皮下和/或表面电极。
    • 9. 发明申请
    • EVALUATING VENTRICULAR SYNCHRONY BASED ON PHASE ANGLE BETWEEN SENSOR SIGNALS
    • 基于传感器信号之间的相位角评估气道同步
    • WO2005018740A1
    • 2005-03-03
    • PCT/US2004/025762
    • 2004-08-10
    • MEDTRONIC, INC.CHINCHOY, EdwardDENO, Curtis, D.CHO, Yong, K.
    • CHINCHOY, EdwardDENO, Curtis, D.CHO, Yong, K.
    • A61N1/365
    • A61N1/368A61N1/3627
    • An implantable medical device evaluates ventricular synchrony by determining a phase angle between at least two sensor signals that reflect mechanical contraction of the ventricles. In exemplary embodiments, two intracardiac impedance signals associated with the right and left ventricles, respectively, with two points within either of the left and right ventricles, or with both the left and right ventricles relative to a reference point, are processed. In such embodiments, fundamental frequency phases of each of the impedance signals may be compared to determine the phase angle between the signals. In some embodiments, the signals are used to dynamically adjust one or more timing intervals, such as a V-V timing interval, for delivery of cardiac resynchronization therapy (CRT) pacing. In such embodiments, the one or more timing intervals are periodically adjusted to reduce or possibly eliminate ventricular dysynchrony as indicated by the phase angle between the sensor signals.
    • 可植入医疗装置通过确定反映心室的机械收缩的至少两个传感器信号之间的相位角来评估心室同步。 在示例性实施例中,处理与左心室和左心室相关联的两个心内阻抗信号,其中左心室和右心室内的两个点,或者与左心室和右心室相对于参考点两者。 在这样的实施例中,可以比较每个阻抗信号的基频相位以确定信号之间的相位角。 在一些实施例中,信号用于动态调整一个或多个定时间隔,例如V-V定时间隔,用于递送心脏再同步治疗(CRT)起搏。 在这样的实施例中,周期性地调整一个或多个定时间隔以减少或可能消除如传感器信号之间的相位角所指示的心室异常。