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41. 发明授权

US06346702B1 Fiber bragg grating peak detection system and method 有权
标题翻译：光纤布拉格光栅峰值检测系统及方法
公开(公告)号：US06346702B1
公开(公告)日：2002-02-12
申请号：US09458911
申请日：1999-12-10
申请人： Michael A. Davis , David R. Fournier , David G. Bellemore , William M. Stielau
发明人： Michael A. Davis , David R. Fournier , David G. Bellemore , William M. Stielau
IPC分类号： G01J104
CPC分类号： H04B10/675
摘要： A fiber Bragg grating peak detection system has a broadband source that provides a broadband optical signal, a fiber Bragg grating and a variable threshold and/or grating profile peak detection unit. The fiber Bragg grating responds to the broadband optical signal, and further responds to a physical parameter, for providing a fiber Bragg grating optical signal containing information about the physical parameter. The variable threshold or grating profile peak detection unit responds to the fiber Bragg grating optical signal, for providing a variable threshold or grating profile peak detection unit signal containing information about a peak detected in the fiber Bragg grating optical signal that is used to determine the physical parameter. The variable threshold or grating profile peak detection unit detects the peak using either a variable threshold peak detection or a grating profile peak detection, or a combination thereof. During the variable threshold peak detection, the variable threshold or grating profile peak detection unit determines a respective local threshold value for each wavelength over a spectral band of the fiber Bragg grating optical signal. During the grating profile peak detection, the detection unit determines a grating profile on each side of the peak.
摘要翻译：光纤布喇格光栅峰值检测系统具有提供宽带光信号的宽带光源，光纤布拉格光栅和可变阈值和/或光栅轮廓峰值检测单元。光纤布拉格光栅响应于宽带光信号，并且进一步响应物理参数，用于提供包含关于物理参数的信息的光纤布拉格光栅光信号。可变阈值或光栅轮廓峰值检测单元响应于光纤布拉格光栅光信号，用于提供可变阈值或光栅轮廓峰值检测单元信号，该信号包含关于在光纤布拉格光栅光信号中检测到的峰值的信息，该信号用于确定物理参数。可变阈值或光栅轮廓峰值检测单元使用可变阈值峰值检测或光栅轮廓峰值检测或其组合来检测峰值。在可变阈值峰值检测期间，可变阈值或光栅轮廓峰值检测单元在光纤布拉格光栅光信号的光谱带上确定每个波长的相应局部阈值。在光栅轮廓峰值检测期间，检测单元确定峰顶两侧的光栅轮廓。

42. 发明授权

US4900540A Lipisomes containing gas for ultrasound detection 失效
标题翻译：含有气体的脂质体超声检测
公开(公告)号：US4900540A
公开(公告)日：1990-02-13
申请号：US505697
申请日：1983-06-20
申请人： Patrick J. Ryan , Michael A. Davis , Donald L. Melchior
发明人： Patrick J. Ryan , Michael A. Davis , Donald L. Melchior
IPC分类号： A61K49/22
CPC分类号： A61K49/227 , Y10S436/829
摘要： Phospholipid liposomes are provided having a lipid bilayer surrounding a confined composition which includes a gas or a gas precursor. The liposomes can be administered to a patient and can be detected in vivo by ultrasound techniques which permit organ imaging.
摘要翻译：提供了具有包围气体或气体前体的限制组合物的脂质双层的磷脂脂质体。脂质体可以施用于患者，并且可以通过允许器官成像的超声技术在体内检测。

43. 发明授权

US4830848A Radiopharmaceutical composition containing tantalum-178 and process therefor 失效
标题翻译：含有钽-178的放射性药物组合物及其制法
公开(公告)号：US4830848A
公开(公告)日：1989-05-16
申请号：US27573
申请日：1987-03-19
申请人： Rudi D. Neirinckx , B. Leonard Holman , Michael A. Davis , Gale I. Harris
发明人： Rudi D. Neirinckx , B. Leonard Holman , Michael A. Davis , Gale I. Harris
IPC分类号： A61K51/02
CPC分类号： A61K51/02 , A61K2123/00
摘要： A physiologically acceptable solution of tantalum-178 having an activity of 0.1 to 200 millicuries per milliliter of tantalum-178 solution is provided. The solution is obtained from tungsten-178 bound to a column of an anion exchange resin which forms tantalum-178 in situ by eluting the column with a hydrochloric acid solution containing hydrogen peroxide to form an acidic solution of tantalum-178. The acidic solution of tantalum-178 then is neutralized.
摘要翻译：提供了活性为0.1至200毫克/毫升钽-178溶液的钽-178的生理上可接受的溶液。该溶液通过与通过用含有过氧化氢的盐酸溶液洗脱柱形成钽-178酸性溶液的柱原位结合到阴离子交换树脂的柱上而获得。然后中和钽-178的酸性溶液。

44. 发明授权

US4288424A Generator for ionic gallium-68 based on column chromatography 失效
标题翻译：基于柱色谱的离子镓-68发生器
公开(公告)号：US4288424A
公开(公告)日：1981-09-08
申请号：US3552
申请日：1979-01-15
申请人： Rudi D. Neirinckx , Michael A. Davis
发明人： Rudi D. Neirinckx , Michael A. Davis
IPC分类号： A61K51/02 , A61K51/12 , G21G1/04 , A61K43/00 , B65D71/00
CPC分类号： A61K51/02 , A61K51/1282 , G21G1/04 , A61K2123/00
摘要： A physiologically acceptable solution of gallium-68 fluorides, having an activity of 0.1 to 50 millicuries per milliliter of solution is provided. The solution is obtained from a generator comprising germanium-68 hexafluoride bound to a column of an anion exchange resin which forms gallium-68 in situ by eluting the column with an acid solution to form a solution containing .sup.68 Ga-fluorides. The solution then is neutralized prior to administration.
摘要翻译：提供了具有0.1-50毫升/毫升溶液活性的镓-68氟化物的生理上可接受的溶液。该溶液是从包含锗六氟化锗的发生器获得的，该六氟化锗结合到阴离子交换树脂的柱上，其通过用酸溶液洗脱柱形成含有68Ga-氟化物的溶液而原位形成镓-68。然后在给药前中和溶液。

45. 发明申请

US20090173883A1 MULTI-BAND FOCAL PLANE ARRAY 有权
标题翻译：多带对焦平面阵列
公开(公告)号：US20090173883A1
公开(公告)日：2009-07-09
申请号：US11493121
申请日：2006-07-26
申请人： Christopher Lee Kauffman , Gerald Pray Griffith , Ronald B. Jones , Sung-Shik Yoo , Michael A. Davis
发明人： Christopher Lee Kauffman , Gerald Pray Griffith , Ronald B. Jones , Sung-Shik Yoo , Michael A. Davis
IPC分类号： H01L27/14 , H01L27/00
CPC分类号： H01L27/14649 , G01J3/36
摘要： A multi-band focal plane array architecture operative to detect multiple spectral image. The multi-band focal plane array architecture has an integrated readout circuit, a plurality of first detectors integrated in the readout circuit and a plurality of second detectors deposited on the readout circuit. Preferably, the first detectors are operative to detect visible signals and the second detectors are operative to detect infrared signals. The first and second detectors are arranged in a checkerboard pattern, in alternate rows or columns, or at least partially overlapped with each other to realize simultaneous detection in two different wavelength bands. The architecture may also have an additional integrated readout circuit flip-chip bonded to the integrated readout circuit. By forming a plurality of third detectors on the additional integrated readout circuit, a tri-band focal plane array may be realized. In one embodiment, a dual-band focal plane array architecture by forming two arrays of detectors on two individual integrated readout circuit and flip-chip bonding these two readout circuits.
摘要翻译：一种可以检测多个光谱图像的多波段焦平面阵列结构。多频带焦平面阵列结构具有集成读出电路，集成在读出电路中的多个第一检测器和沉积在读出电路上的多个第二检测器。优选地，第一检测器可操作以检测可见信号，并且第二检测器可操作以检测红外信号。第一和第二检测器被布置成棋盘图案，以交替行或列排列，或至少部分地彼此重叠，以实现两个不同波长带中的同时检测。该架构还可以具有结合到集成读出电路的额外的集成读出电路倒装芯片。通过在附加集成读出电路上形成多个第三检测器，可以实现三波段焦平面阵列。在一个实施例中，双波段焦平面阵列架构通过在两个单独的集成读出电路上形成两个检测器阵列并将这两个读出电路进行倒装芯片接合。

46. 发明授权

US07123833B2 Dynamically reconfigurable optical smart node 有权
公开(公告)号：US07123833B2
公开(公告)日：2006-10-17
申请号：US10216000
申请日：2002-08-08
申请人： Paul Szczepanek , Jay W. Dawson , John A. Moon , Michael A. Davis
发明人： Paul Szczepanek , Jay W. Dawson , John A. Moon , Michael A. Davis
IPC分类号： H04B10/08
CPC分类号： H04J14/0221 , H04B10/0797
摘要： A smart node is provided for use in an optical communications network wherein the smart node comprising dynamically reconfigurable optical signal manipulation devices in combination with sensing devices and processors to provide real time closed and open loop control of various channels of the network.

47. 发明授权

US06956687B2 Optical blocking filter having an array of micro-mirrors 有权
标题翻译：具有微镜阵列的光阻挡滤光器
公开(公告)号：US06956687B2
公开(公告)日：2005-10-18
申请号：US10327695
申请日：2002-12-19
申请人： John A. Moon , Alan D. Kersey , James S. Sirkis , James R. Dunphy , Joseph Pinto , Paul Szczepanek , Michael A. Davis , Martin A. Putnam
发明人： John A. Moon , Alan D. Kersey , James S. Sirkis , James R. Dunphy , Joseph Pinto , Paul Szczepanek , Michael A. Davis , Martin A. Putnam
IPC分类号： G02B6/26 , G02B6/34 , G02B6/42 , G02B26/08 , G02B27/10 , H04J14/02 , H04Q11/00 , G02B26/00
CPC分类号： G02B6/29394 , G01J3/021 , G01J3/0229 , G02B6/262 , G02B6/266 , G02B6/4226 , G02B26/0833 , G02B26/0841 , G02B27/1086 , H04J14/0212 , H04J14/0213 , H04J14/0221 , H04Q2011/0009 , H04Q2011/0026 , Y10S359/904
摘要： A reconfigurable optical blocking filter deletes a desired optical channel(s) from an optical WDM input signal, and includes a spatial light modulator having a micro-mirror device with a two-dimensional array of micro-mirrors that tilt between first and second positions in a “digital” fashion in response to a control signal provided by a controller in accordance with a switching algorithm and an input command. A collimators, diffraction grating, and Fourier lens, collectively collimate, separate and focus the optical input channels onto the array of micro-mirrors. The optical channel is focused on the micro-mirrors onto a plurality of micro-mirrors of the micro-mirror device, which effectively pixelates the optical channels. To delete an input channel of the optical input signal, micro-mirrors associated with each desired input channel are tilted to reflect the desired input channel away from the return path.
摘要翻译：可重构光阻断滤波器从光WDM输入信号中删除期望的光信道，并且包括具有微镜装置的空间光调制器，该微镜装置具有在第一和第二位置之间倾斜的微镜的二维阵列响应于由控制器根据切换算法和输入命令提供的控制信号的“数字”方式。准直仪，衍射光栅和傅立叶透镜共同校准，分离并将光学输入通道聚焦到微镜阵列上。光通道聚焦在微镜上到微镜装置的多个微反射镜上，这有效地像化了光通道。为了删除光输入信号的输入通道，与每个期望的输入通道相关联的微反射镜被倾斜以反射所需的输入通道远离返回路径。

48. 发明授权

US06934069B2 Chromatic dispersion compensation device having an array of micromirrors 有权
标题翻译：具有微镜阵列的色散补偿装置
公开(公告)号：US06934069B2
公开(公告)日：2005-08-23
申请号：US10298264
申请日：2002-11-15
申请人： John A. Moon , Alan D. Kersey , Jay W. Dawson , Joseph Pinto , James R. Dunphy , Michael A. Davis
发明人： John A. Moon , Alan D. Kersey , Jay W. Dawson , Joseph Pinto , James R. Dunphy , Michael A. Davis
IPC分类号： G02B6/26 , G02B6/34 , G02B6/42 , G02B26/08 , G02B27/10 , H04J14/02 , H04Q11/00 , G02B26/00 , H04B10/12
CPC分类号： G02B6/29311 , G02B6/262 , G02B6/266 , G02B6/29394 , G02B6/29395 , G02B6/4226 , G02B26/0833 , G02B26/0841 , G02B27/1086 , H04J14/021 , H04J14/0212 , H04J14/0213 , H04J14/0221 , H04Q2011/0009 , H04Q2011/0026
摘要： A chromatic dispersion compensation device selectively delays a respective portion of spectral sections of each respective optical channel of an optical WDM input signal to compensate each optical channel for dispersion compensation, and includes a spatial light modulator having a micromirror device with a two-dimensional array of micromirrors. The micromirrors tilt or flip between first and second positions in a “digital” fashion in response to a control signal provided by a controller in accordance with a switching algorithm and an input command. A collimator, diffraction gratings, and Fourier lens collectively collimate, disperse and focus the optical input channels onto the array of micromirrors. Each optical channel is focused onto micromirrors of the micromirror device, which effectively pixelates the optical channels. To compensate an optical channel for chromatic dispersion, a portion of the spectral sections of each channel is delayed a desired time period by tilting an array of mirrors (i.e., spectral array) disposed in each spectral section at different spatial positions on the micromirror device.
摘要翻译：色散补偿装置选择性地延迟光WDM输入信号的每个相应光通道的光谱部分的相应部分以补偿每个光信道用于色散补偿，并且包括空间光调制器，具有具有二维阵列的微镜器件微镜。响应于由控制器根据切换算法和输入命令提供的控制信号，微镜以“数字”方式在第一和第二位置之间倾斜或翻转。准直仪，衍射光栅和傅立叶透镜共同准直，分散并将光学输入通道聚焦到微镜阵列上。每个光通道聚焦到微镜器件的微镜上，这有效地使光通道成像。为了补偿用于色散的光信道，通过在微镜装置上的不同空间位置倾斜设置在每个光谱部分中的反射镜阵列（即，光谱阵列），将每个通道的光谱部分的一部分延迟期望的时间段。

49. 发明授权

US06804693B2 Method for reducing skew in a real-time centroid calculation 有权
标题翻译：减少实时重心计算中的偏差的方法
公开(公告)号：US06804693B2
公开(公告)日：2004-10-12
申请号：US09929423
申请日：2001-08-14
申请人： David G. Bellemore , David R. Fournier , Michael A. Davis
发明人： David G. Bellemore , David R. Fournier , Michael A. Davis
IPC分类号： G06F700
CPC分类号： G01R19/04 , G01L1/246 , G01R19/2509
摘要： A method and corresponding apparatus for determining the centroid (Vc) of a waveform signal being sampled at a set of parameter values (Vi, i=1, . . . , n) yielding a corresponding set of sampled amplitudes (Ai, i=1, . . . , n), each parameter value and corresponding amplitude forming a sampled point (Vi, Ai), the method including the steps of: selecting an amplitude at which to create an interpolated point; interpolating a first parameter value corresponding to the amplitude selected in the step of selecting an amplitude; and performing a centroid calculation using only the sampled points with an amplitude greater than a predetermined threshold. The waveform is sometimes sampled in the presence of background noise, and the method sometimes also includes: estimating the background (Bi) for each value in the set of parameter values at which sampling is performed; and reducing the amplitude (Ai) of each sampled amplitude by the background (Bi) so estimated.
摘要翻译：一种用于确定在一组参数值（Vi，i = 1，...，n）上采样的波形信号的质心（Vc）的方法和相应装置，产生一组相应的采样幅度（Ai，i = 1 ，...，n），每个参数值和对应的幅度形成采样点（Vi，Ai），所述方法包括以下步骤：选择创建内插点的幅度; 内插与在选择幅度的步骤中选择的幅度对应的第一参数值; 以及仅使用振幅大于预定阈值的采样点进行质心计算。有时在有背景噪声的情况下采样波形，并且该方法有时还包括：对进行采样的参数值集合中的每个值估计背景（Bi）; 并且将每个采样振幅的振幅（Ai）减小所估计的背景（Bi）。

50. 发明授权

US06529923B2 Method for improving the accuracy in the determination of a waveform center of a waveform signal 失效
公开(公告)号：US06529923B2
公开(公告)日：2003-03-04
申请号：US09087447
申请日：1998-05-29
申请人： Michael A. Davis , David G. Bellemore
发明人： Michael A. Davis , David G. Bellemore
IPC分类号： G06F700
CPC分类号： G01R19/2509 , G01R19/04 , G01R23/02
摘要： Prior to performing a centroid calculation on a waveform signal that is discretely sampled at a limited number of sample points, the last sample point (VN, AN) is eliminated if the magnitude of the amplitude at the first sample point (A1) is greater than the last sample point (AN), and the difference in magnitude between the first and last sample points (A1−AN) is greater than the difference in magnitude between the second to last sample point and the first sample point (AN−1−A1). The first sample point (V1, A1) is eliminated prior to the centroid calculation if the magnitude of the amplitude at the last sample point (AN) is greater than the first sample point (A1), and the difference in magnitude between the last and first sample points (AN−A1) is greater than the difference in magnitude between the second sample point and the last sample point (A2−AN). In a second embodiment of the invention, a first centroid calculation is performed using a set of samples in which one side of the waveform signal has the lowest amplitude value sample. Sample values on the side of the waveform initially having the lowest amplitude value are then eliminated until the opposing side of the waveform has the lowest amplitude value sample. A second centroid calculation is then performed and the two centroid calculations are averaged together to arrive at an average centroid calculation. In a third embodiment of the invention, the amplitude components of the waveform sample values are normalized to the lowest amplitude value sample point and a first centroid calculation is performed on the normalized waveform signal. Next, the waveform is normalized to the lowest amplitude value sample point on the other side of the waveform signal and a second centroid calculation is performed. The two centroid calculations are then averaged to provide an averaged normalized centroid calculation.

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