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21. 发明申请

US20110094590A1 Method For Operating a Fluid Valve Via An Oscillating Valve Motion 有权
标题翻译：通过振荡阀运动操作流体阀的方法
公开(公告)号：US20110094590A1
公开(公告)日：2011-04-28
申请号：US12737322
申请日：2009-05-28
申请人： Juergen Hessenauer , Jose Kissler , Ulrich Foerch , Manfred Schmitt , Steffen Schumacher , Nicole Weber , Oliver Schell , Christof Ott
发明人： Juergen Hessenauer , Jose Kissler , Ulrich Foerch , Manfred Schmitt , Steffen Schumacher , Nicole Weber , Oliver Schell , Christof Ott
IPC分类号： F15D1/00 , F16K31/02
CPC分类号： G05D16/2013 , F16K31/0675 , G05D7/0635 , G05D16/202 , Y10T137/0318 , Y10T137/7761
摘要： In a method for operating a fluid valve for controlling or regulating a fluid, having at least one movable valve component is displaceable with the aid of at least one electrical actuating signal which contains at least one first actuating signal portion which causes an oscillating valve motion of the valve component. Pressure oscillations generated in the fluid due to the oscillating valve motion are detected, and are used for regulation of the oscillating valve motion caused by the first actuating signal portion.
摘要翻译：在用于操作用于控制或调节流体的流体阀的方法中，具有至少一个可移动阀部件可借助于至少一个电致动信号而移动，所述至少一个电致动信号包含至少一个第一致动信号部分，该第一致动信号部分引起振荡阀运动阀组件。检测由于振荡阀运动而在流体中产生的压力振荡，并且用于调节由第一致动信号部分引起的振荡阀运动。

22. 发明申请

US20100058759A1 Device and method for operating an internal combustion engine, computer program, computer program product 有权
标题翻译：用于操作内燃机，计算机程序，计算机程序产品的装置和方法
公开(公告)号：US20100058759A1
公开(公告)日：2010-03-11
申请号：US12437032
申请日：2009-05-07
申请人： Guillaume Huard , Juergen Stegmaier , Henrick Brandes , Martin Cichon , Manfred Schmitt , Lutz Rauchfuss , Oliver Tschismar
发明人： Guillaume Huard , Juergen Stegmaier , Henrick Brandes , Martin Cichon , Manfred Schmitt , Lutz Rauchfuss , Oliver Tschismar
IPC分类号： F02G3/00
CPC分类号： F01N5/02 , F01K23/065 , F01K23/101 , F02G5/02 , Y02T10/16 , Y02T10/166
摘要： For operating an internal combustion engine having a throttle situated in an exhaust line or exhaust return line, in which a heat engine is driven by a quantity of heat produced by the internal combustion engine, in a first non-heating operating mode of the internal combustion engine, a first setpoint value is preset, a first operating parameter that characterizes a temperature of the internal combustion engine is detected, a first triggering value is determined for the triggering of the at least one throttle as a function of the first setpoint value and the first operating parameter, the at least one throttle is triggered in accordance with the first triggering value, and the at least one heat engine is driven by the resulting quantity of heat.
摘要翻译：为了操作具有位于排气管线或排气返回管路中的节气门的内燃机，其中热内燃机由内燃机产生的一定量的热量驱动，内燃机的第一非加热运行模式发动机，预先设定第一设定值，检测表征内燃机的温度的第一操作参数，确定作为第一设定值的函数的至少一个节气门的触发的第一触发值，以及第一操作参数，根据第一触发值触发至少一个节气门，并且由所得到的热量驱动至少一个热机。

23. 发明申请

US20080254447A1 Method and Nucleic Acids for the Improved Treatment of Breast Cell Proliferative Disorders 有权
标题翻译：改善乳腺增生性疾病治疗的方法和核酸
公开(公告)号：US20080254447A1
公开(公告)日：2008-10-16
申请号：US10582705
申请日：2004-12-13
申请人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John Martens , Fabian Model , Inko Nimmrich , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth , Ina Schwope , Oliver Hartmann , Peter Adorjan , Almuth Marx , Heinz Hoefler
发明人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John Martens , Fabian Model , Inko Nimmrich , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth , Ina Schwope , Oliver Hartmann , Peter Adorjan , Almuth Marx , Heinz Hoefler
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16
摘要： The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the disease free survival and/or response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
摘要翻译：本发明涉及修饰和基因组序列，用于检测基因组DNA的胞嘧啶甲基化状态的寡核苷酸和/或PNA寡聚体，以及用于预测受试者与细胞的无病存活和/或应答的方法乳腺组织增生性疾病，进行内分泌治疗。

24. 发明申请

US20070068407A1 Sheet guiding device for sheet feeders 审中-公开
标题翻译：纸张进给器的纸张引导装置
公开(公告)号：US20070068407A1
公开(公告)日：2007-03-29
申请号：US11528928
申请日：2006-09-28
申请人： Manfred Schmitt
发明人： Manfred Schmitt
IPC分类号： B65H3/08
CPC分类号： B65H3/0825 , B65H3/48 , B65H3/68
摘要： A sheet-guiding device in a feed region of a sheet-processing machine includes a suction head settable to a format length of a sheet and flexible sheet-guiding elements disposed above a sheet conveying plane. The sheet-guiding elements have a constant length, are disposed so as to be stationary and are deflectable by a positional change of the suction head.
摘要翻译：片材加工机的进给区域中的片材引导装置包括可设置成片材的格式长度的吸头和设置在片材输送面上方的柔性片引导元件。片材引导元件具有恒定的长度，被布置成静止并且可通过吸头的位置变化而偏转。

25. 发明申请

US20070066798A1 Diagnostic and therapeutic use of antibodies against the urokinase receptor 有权
公开(公告)号：US20070066798A1
公开(公告)日：2007-03-22
申请号：US11586579
申请日：2006-10-26
申请人： Manfred Schmitt , Viktor Magdolen , Thomas Luther , Sybille Albrecht , Martin Muller , Olaf Wilhelm , Nadja Harbeck
发明人： Manfred Schmitt , Viktor Magdolen , Thomas Luther , Sybille Albrecht , Martin Muller , Olaf Wilhelm , Nadja Harbeck
IPC分类号： C12Q1/68 , C07K14/00 , C07K16/00 , A61K38/00 , C07K17/00 , C07K2/00 , C07K4/00 , C07K5/00 , C07K7/00
CPC分类号： C07K16/28 , A61K47/6849 , A61K51/1027 , A61K2039/505 , C07K16/2896 , C07K2317/565 , C07K2317/622 , G01N33/574 , G01N33/57492 , G01N33/582
摘要： The invention concerns a method and a reagent kit for detecting cells in a biological sample using a double-fluorescence technique and the diagnostic and therapeutic application of amino acid sequence-specific antibodies against the urokinase receptor having a high affinity for tumour cell-expressed receptors.

26. 发明授权

US06528619B1 Inhibitors for urokinase receptor 失效
标题翻译：尿激酶受体抑制剂
公开(公告)号：US06528619B1
公开(公告)日：2003-03-04
申请号：US09402641
申请日：2000-01-10
申请人： Markus Bürgle , Heinrich Graeff , Horst Kessler , Viktor Magdolen , Bernhard König , Marcus Koppitz , Christoph Riemer , Manfred Schmitt , Ulrich Weidle
发明人： Markus Bürgle , Heinrich Graeff , Horst Kessler , Viktor Magdolen , Bernhard König , Marcus Koppitz , Christoph Riemer , Manfred Schmitt , Ulrich Weidle
IPC分类号： C07K708
CPC分类号： C12N9/6462 , C12Y304/21073
摘要： The present invention provides peptides as inhibitors of the binding of urokinase to the urokinase receptor. The peptides have the general structural formula (I): X1-[X2]n-X3-X4-K-Y-F-X5-X6-I-X7-W-[X8]m (I) in which X1, X2, X3, X4, X5, X6, X7 and X8 each denote an aminocarboxylic acid, n and m are each independently 0 or 1, K denotes an aminocarboxylic acid with a lysine side chain, Y denotes an aminocarboxylic acid with a tyrosine side chain, F denotes an aminocarboxylic acid with a phenyl-alanine side chain, I denotes an aminocarboxylic acid with an isoleucine side chain, W denotes an aminocarboxylic acid with a tryptophan side chain, and the monomeric building blocks are linked by —CONR1— or —NR1CO— bonds where R1 in each case independently denotes hydrogen, methyl or ethyl, and pharmaceutically compatible salts and derivatives thereof.
摘要翻译：本发明提供肽作为尿激酶与尿激酶受体结合的抑制剂。肽具有通式结构式（I）：其中X 1，X 2，X 3，X 4，X 5，X 6，X 7和X 8各自表示氨基羧酸，n和m各自独立地为0或1，K表示氨基羧酸，赖氨酸侧链，Y表示具有酪氨酸侧链的氨基羧酸，F表示具有苯基 - 丙氨酸侧链的氨基羧酸，I表示具有异亮氨酸侧链的氨基羧酸，W表示具有色氨酸侧链的氨基羧酸，并且单体结构单元通过-CONR1-或-NR1CO-键连接，其中R 1在每种情况下独立地表示氢，甲基或乙基，以及其药学上相容的盐和衍生物。

27. 发明授权

US06279626B1 Closure cap for a tank 失效
标题翻译：一个坦克的封闭帽
公开(公告)号：US06279626B1
公开(公告)日：2001-08-28
申请号：US09530526
申请日：2000-09-18
申请人： Manfred Schmitt , Ulrich Kappenstein
发明人： Manfred Schmitt , Ulrich Kappenstein
IPC分类号： B65B104
CPC分类号： E05B83/34 , B60K15/0409 , B60K15/05 , B60K2015/0429 , B60K2015/053 , B60K2015/0538 , B60K2015/0584
摘要： A closure for a tank, in particular a fuel tank for a motor vehicle or the like, that has a tank filling pipe which can be closed with a closure flap, is described. The closure flap has a locking device with which it can be locked and unlocked and is also connected by a hinge or the like, so that it can move into the interior of the tank filling pipe. The locking device is located completely beneath the closure flap so that the closure flap can be locked and unlocked. Thus the locking device is not accessible from the outside, so it cannot be damaged or operated by an unauthorized party. The tank filling pipe can also be sealed airtight by the closure flap or by a closure valve arranged in the tank filling pipe.
摘要翻译：描述了一种用于罐的封闭物，特别是用于机动车辆等的燃料箱，其具有可以用闭合盖关闭的罐填充管。封闭翼片具有锁定装置，通过该锁定装置可以锁定和解锁，并且还通过铰链等连接，使得其能够移动到储罐填充管的内部。锁定装置完全位于封闭翼片的下面，使得封闭翼片能被锁定和解锁。因此，锁定装置不能从外部接近，所以不能被未经授权的一方损坏或操作。罐填充管也可以通过闭合盖或通过设置在罐填充管中的封闭阀密封。

28. 发明授权

US5048899A Anti-skid and traction control apparatus for a vehicle 失效
标题翻译：用于车辆的防滑和牵引控制装置
公开(公告)号：US5048899A
公开(公告)日：1991-09-17
申请号：US466114
申请日：1990-01-16
申请人： Manfred Schmitt , Norbert Rittmannsberger
发明人： Manfred Schmitt , Norbert Rittmannsberger
IPC分类号： B60T8/175 , B60T8/40 , B60T8/42 , B60T8/48
CPC分类号： B60T8/4872 , B60T8/4063 , B60T8/4275
摘要： A system applicable to motor vehicles having a master brake cylinder with a pressure fluid supply container and at least one pressure control valve assembly is associated with a wheel brake. A pump provided which in the anti-skid mode pumps pressure fluid drawn from the wheel brake to the master brake cylinder by use of the pressure control valve assembly. In a traction control mode, the pump draws pressure fluid from the master brake cylinder and forces it to the wheel brake. To this end, the pressure control valve assembly has a first line connection communicating with the master brake cylinder, a second line connection communicating with the wheel brake, and a third line connection through which quantities of pressure fluid flows in the anti-skid mode to reduce the wheel brake pressure. Both simple design and increased functional reliability of the system are attained by providing that in the traction control mode, the third line connection of the pressure control valve assembly communicates with a pressure outlet of the pump.
摘要翻译：适用于具有带有压力流体供应容器的主制动缸和至少一个压力控制阀组件的机动车辆的系统与车轮制动器相关联。设置有防滑模式的泵通过使用压力控制阀组件将从车轮制动器拉出的流体压向主制动缸。在牵引力控制模式下，泵从主制动缸吸取压力流体并将其推到车轮制动器。为此，压力控制阀组件具有与主制动缸连通的第一线路连接，与车轮制动器连通的第二线路连接，以及第三线路连接，通过该第三线路连接，多个压力流体以防滑模式流动到降低车轮制动压力。通过提供在牵引力控制模式中，压力控制阀组件的第三线连接与泵的压力出口连通，实现了系统的简单设计和增加的功能可靠性。

29. 发明授权

US4911192A Method of and apparatus for control of saftey valves 失效
标题翻译：控制安全阀的方法和装置
公开(公告)号：US4911192A
公开(公告)日：1990-03-27
申请号：US221458
申请日：1988-06-03
申请人： Johannes Hartfiel , Manfred Schmitt
发明人： Johannes Hartfiel , Manfred Schmitt
IPC分类号： F16K17/00 , F16K31/06 , F16K31/42 , G05D16/20
CPC分类号： G05D16/2093 , F15B19/002 , F16K17/02 , F16K31/1245 , F15B2211/50509 , F15B2211/50554 , F15B2211/5158 , F15B2211/5159 , F15B2211/527 , Y10T137/0396 , Y10T137/7761 , Y10T137/86389
摘要： A method of and apparatus for controlling a system safety valve comprising an operating cylinder for displacing a valve closing member, and in which outflow and inflow solenoid valves communicating with the operating cylinder for guiding hydraulic fluid out of and into the operating cylinder, respectively, are electronically controlled in accordance with the system pressure to enable stepwise opening or closing of the safety valve.
摘要翻译： PCT No.PCT / DE87 / 00446 Sec。 371日期：1988年6月3日 102（e）日期1988年6月3日PCT提交1987年10月1日PCT公布。出版物WO88 / 02510 日期：1988年4月7日。一种用于控制系统安全阀的方法和装置，包括用于移动阀关闭构件的操作气缸，并且其中与操作气缸连通的流出和流入电磁阀用于将液压流体引导到操作缸分别根据系统压力进行电子控制，以便能够逐步打开或关闭安全阀。

30. 发明授权

US4643219A Valve for regulating the passage of a fluid 失效
标题翻译：用于调节流体通过的阀
公开(公告)号：US4643219A
公开(公告)日：1987-02-17
申请号：US513987
申请日：1983-07-14
申请人： Manfred Schmitt , Herbert Illius
发明人： Manfred Schmitt , Herbert Illius
IPC分类号： F16K27/02 , F16K1/00 , F16K1/32 , F16K31/06 , F16K31/122 , F16K35/16 , F16K37/00 , G21D1/00 , G21D1/04 , F16K25/00
CPC分类号： F16K1/00 , F16K31/122 , F16K37/0041 , Y10T137/7668 , Y10T137/8085 , Y10T137/8242 , Y10T137/8359
摘要： A valve for regulating the passage of a fluid through pipes, in particular pipes having a large diameter, has a valve housing and a valve unit. The valve unit includes a spindle movable in vertical direction in the housing and is connected to a valve disk which reciprocates in a flow cylinder having a perforated casing. The spindle is further connected to a lifting cylinder which provides the movement of the spindle and the valve disk between a shutoff position and an open position. The valve unit of the valve is insertable into the housing and removable therefrom in its entirety without necessitating a dismantling of the housing.
摘要翻译：用于调节流体通过管道，特别是具有大直径的管道的阀具有阀壳体和阀单元。阀单元包括在壳体中可在垂直方向上移动的主轴，并连接到在具有多孔壳体的流动缸中往复运动的阀盘。主轴还连接到提升缸，其提供主轴和阀盘在关闭位置和打开位置之间的运动。阀的阀单元可插入壳体中并且可全部移除，而不需要拆卸壳体。

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