专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20080254447A1 Method and Nucleic Acids for the Improved Treatment of Breast Cell Proliferative Disorders 有权
标题翻译：改善乳腺增生性疾病治疗的方法和核酸
公开(公告)号：US20080254447A1
公开(公告)日：2008-10-16
申请号：US10582705
申请日：2004-12-13
申请人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John Martens , Fabian Model , Inko Nimmrich , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth , Ina Schwope , Oliver Hartmann , Peter Adorjan , Almuth Marx , Heinz Hoefler
发明人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John Martens , Fabian Model , Inko Nimmrich , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth , Ina Schwope , Oliver Hartmann , Peter Adorjan , Almuth Marx , Heinz Hoefler
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16
摘要： The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the disease free survival and/or response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
摘要翻译：本发明涉及修饰和基因组序列，用于检测基因组DNA的胞嘧啶甲基化状态的寡核苷酸和/或PNA寡聚体，以及用于预测受试者与细胞的无病存活和/或应答的方法乳腺组织增生性疾病，进行内分泌治疗。

2. 发明授权

US09017944B2 Methods for the prognosis of breast cancer 有权
标题翻译：乳腺癌预后的方法
公开(公告)号：US09017944B2
公开(公告)日：2015-04-28
申请号：US10582705
申请日：2004-12-13
申请人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John W. Martens , Fabian Model , Inko Nimmrich , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth Lukas , Ina Schwope , Oliver Hartmann , Peter Adorjan , Almuth Marx , Heinz Hoefler
发明人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John W. Martens , Fabian Model , Inko Nimmrich , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth Lukas , Ina Schwope , Oliver Hartmann , Peter Adorjan , Almuth Marx , Heinz Hoefler
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16
摘要： The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the disease free survival and/or response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
摘要翻译：本发明涉及修饰和基因组序列，用于检测基因组DNA的胞嘧啶甲基化状态的寡核苷酸和/或PNA寡聚体，以及用于预测受试者与细胞的无病存活和/或应答的方法乳腺组织增生性疾病，进行内分泌治疗。

3. 发明申请

US20060024684A1 Prognostic markers for prediction of treatment response and/or survival of breast cell proliferative disorder patients 审中-公开
公开(公告)号：US20060024684A1
公开(公告)日：2006-02-02
申请号：US11011332
申请日：2004-12-13
申请人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John Martens , Fabian Model , Inko Nimmrich , Tamas Rujan , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth , Ina Schwope , Oliver Hartmann , Peter Adorjan
发明人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John Martens , Fabian Model , Inko Nimmrich , Tamas Rujan , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth , Ina Schwope , Oliver Hartmann , Peter Adorjan
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/154 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16
摘要： Aspects of the present invention provide compositions and methods for prognosis of, and/or predicting the estrogen treatment outcome of breast cell proliferative disorder patients, and in particular of patients with breast carcinoma. In preferred embodiments, this is achieved, at least in part, by determining the expression level of PITX2, and/or the genetic or the epigenetic modifications of the genomic DNA associated with the gene PITX2. Additional aspects of the invention provide novel sequences, oligomers (e.g., oligonucleotides or peptide nucleic acid (PNA)-oligomers), and antibodies, which have substantial utility in the described inventive methods and compositions.

4. 发明申请

US20090269736A1 Prognostic markers for prediction of treatment response and/or survival of breast cell proliferative disorder patients 审中-公开
标题翻译：用于预测乳腺增生性疾病患者的治疗反应和/或存活的预后标志物
公开(公告)号：US20090269736A1
公开(公告)日：2009-10-29
申请号：US11628703
申请日：2005-06-06
申请人： Inko Nimmrich , Ralf Lesche , Ina Schwope , Sabine Maier , Antje Kluth Lukas , Oliver Hartmann , Almuth Marx
发明人： Inko Nimmrich , Ralf Lesche , Ina Schwope , Sabine Maier , Antje Kluth Lukas , Oliver Hartmann , Almuth Marx
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/154 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16
摘要： Aspects of the present invention provide compositions and methods for prognosis of, and/or predicting the estrogen treatment outcome of breast cell proliferative disorder patients, and in particular of patients with breast carcinoma. In preferred embodiments, this is achieved, at least in part, by determining the expression level of PITX2, and/or the genetic or the epigenetic modifications of the genomic DNA associated with the gene PITX2. Additional aspects of the invention provide novel sequences, oligomers (e.g., oligonucleotides or peptide nucleic acid (PNA)-oligomers), and antibodies, which have substantial utility in the described inventive methods and compositions.
摘要翻译：本发明的方面提供了用于预测和/或预测乳腺增生性疾病患者，特别是乳腺癌患者的雌激素治疗结果的组合物和方法。在优选的实施方案中，这通过确定PITX2的表达水平和/或与基因PITX2相关的基因组DNA的遗传或表观遗传修饰至少部分地实现。本发明的另外的方面提供新的序列，低聚物（例如，寡核苷酸或肽核酸（PNA）寡聚体））和抗体，其在所述的发明方法和组合物中具有实用性。

5. 发明申请

US20130096052A1 PROCALCITONIN FOR THE DIAGNOSIS OF BACTERIAL INFECTIONS AND GUIDANCE OF ANTIBIOTIC TREATMENT IN PATIENTS WITH NON-SPECIFIC COMPLAINTS 审中-公开
标题翻译：用于诊断细菌感染的方案和针对非特异性投诉患者的抗生素治疗指南
公开(公告)号：US20130096052A1
公开(公告)日：2013-04-18
申请号：US13583350
申请日：2011-03-08
申请人： Joachim Struck , Christian Nickel , Roland Bingisser , Sven Giersdorf , Oliver Hartmann
发明人： Joachim Struck , Christian Nickel , Roland Bingisser , Sven Giersdorf , Oliver Hartmann
IPC分类号： G01N33/74
CPC分类号： G01N33/74 , G01N33/56911 , G01N2333/585 , G01N2800/52
摘要： The present invention relates to the determination of the level of marker peptides in a sample derived from a bodily fluid of a subject presenting with non-specific complaints.
摘要翻译：本发明涉及确定来源于患有非特异性投诉的受试者的体液的样品中标记肽的水平。

6. 发明申请

US20090304342A1 TERMINAL BOX FOR FIBEROPTIC CABLES AND PANEL 有权
标题翻译：用于纤维电缆和面板的终端盒
公开(公告)号：US20090304342A1
公开(公告)日：2009-12-10
申请号：US12479932
申请日：2009-06-08
申请人： Jorg Adomeit , Oliver Hartmann , Ulrich Hetzer , Pia Kopf , Frank Mossner , Michael Sielaff
发明人： Jorg Adomeit , Oliver Hartmann , Ulrich Hetzer , Pia Kopf , Frank Mossner , Michael Sielaff
IPC分类号： G02B6/00
CPC分类号： G02B6/4455 , G02B6/445
摘要： The invention relates to a terminal box (1) for fiberoptic cables, comprising an at least two-part housing with a lower part (3) and a cover (2), the cover (2) being arranged pivotably on the lower part (3), at least one receptacle for a splice, at least one feed (10) for a fiberoptic cable and a receptacle (11) for a coupling, the side faces (5, 6) of the cover (2) being longer than the end faces (7, 8) of the cover (2), a pivot bearing of the cover (2) being arranged on an end face (8) of the cover (2), and to a panel for accommodating a terminal box (1) for fiberoptic cables.
摘要翻译：本发明涉及一种用于光纤电缆的接线盒（1），包括具有下部（3）和盖（2）的至少两部分壳体，所述盖（2）可枢转地布置在下部（3）上），用于接头的至少一个插座，用于光纤电缆的至少一个馈送（10）和用于联接的插座（11），盖（2）的侧面（5,6）比端部盖（2）的表面（7,8），盖（2）的枢轴支承件布置在盖（2）的端面（8）上，并且连接到用于容纳接线盒（1）的面板用于光纤电缆。

7. 发明授权

US09007734B2 Method and safety device for monitoring a bus bar of an electrical energy supply grid 有权
标题翻译：用于监测电力供电电网母线的方法和安全装置
公开(公告)号：US09007734B2
公开(公告)日：2015-04-14
申请号：US13133256
申请日：2008-12-10
申请人： Oliver Hartmann
发明人： Oliver Hartmann
IPC分类号： H02H3/02 , H02H7/26
CPC分类号： H02H7/262
摘要： A method for monitoring a bus bar with regard to short circuits that may occur. The bus bar has a feeder and at least two outgoers. A outgoer safety device is provided at each outgoer and a feeder safety device is provided at the feeder. In the case of a short circuit in one of the outgoers, the outgoer safety device associated with the outgoer outputs a blocking signal to the feeder safety device, delaying or preventing actuation of a power switch disposed at the feeder. In order to provide a method wherein comparably little installation effort is required, the outgoer safety devices send repeating communication telegrams to the feeder safety device by way of a data transfer bus, and the feeder safety device checks the receipt of the communication telegrams by way of a checking logic, and optionally prevents the execution of a blocking signal. A feeder safety device is correspondingly configured.
摘要翻译：一种用于监测可能发生的短路的母线的方法。母线有一个喂料器和至少两个出口者。每个出口人都设置一个外放安全装置，并在送料器上设置一个送料器安全装置。在其中一个输出器发生短路的情况下，与输出器相关联的外放器安全装置向加料器安全装置输出阻塞信号，延迟或防止设置在进料器上的电源开关的致动。为了提供一种需要相当少的安装努力的方法，外出者安全装置通过数据传输总线向馈线安全装置发送重复的通信电报，馈线安全装置通过以下方式检查通信电报的接收：检查逻辑，并且可选地防止执行阻塞信号。进料器安全装置相应配置。

8. 发明申请

US20130098677A1 DISTRIBUTION CABINET FOR OPTICAL FIBRE CABLES 有权
标题翻译：光纤电缆分配柜
公开(公告)号：US20130098677A1
公开(公告)日：2013-04-25
申请号：US13576594
申请日：2010-11-02
申请人： Adrian Benedetto , Oliver Hartmann , Frank Mössner , Michael Sielaff , Thomas Fischer
发明人： Adrian Benedetto , Oliver Hartmann , Frank Mössner , Michael Sielaff , Thomas Fischer
IPC分类号： H02G3/14 , G02B6/44
CPC分类号： H02G3/14 , G02B6/4441 , G02B6/4452 , G02B6/4477 , Y10S248/906
摘要： The invention relates to a box (1) for accommodating and laying optical waveguides and/or copper conductors, with the box (1) comprising at least one housing (10) and at least one cover (20), with the cover (20) being attached to the housing (10) such that it can pivot, with the cover (20) being attached to the housing (10) such that it can be detached, with the cover (20) having at least one receptacle for a pin element (90), with the housing (10) having at least one pin element (90), it being possible for the at least one pin element (90) to be held by means of the receptacle for a pin element (90), and it being possible for the at least one pin element (90) to be displaced parallel to a pivot axis relative to the holding element (80).
摘要翻译：本发明涉及一种用于容纳和铺设光波导和/或铜导体的盒（1），盒（1）包括至少一个壳体（10）和至少一个盖（20），盖子（20）附接到壳体（10），使得其可以枢转，其中盖（20）附接到壳体（10），使得其可以被拆卸，盖（20）具有用于销元件的至少一个容座（90），其中所述壳体（10）具有至少一个销元件（90），所述至少一个销元件（90）可以通过所述插座来保持用于销元件（90），并且所述至少一个销元件（90）可相对于所述保持元件（80）平行于枢转轴线移位。

9. 发明申请

US20120002935A1 STRAIN RELIEF DEVICE 审中-公开
标题翻译：应变消除装置
公开(公告)号：US20120002935A1
公开(公告)日：2012-01-05
申请号：US13255746
申请日：2009-12-16
申请人： Oliver Hartmann
发明人： Oliver Hartmann
IPC分类号： G02B6/44
CPC分类号： G02B6/4477
摘要： The invention relates to a strain relief device (1) for at least one glass fiber cable (45), comprising a base body (10) and at least one clamping element (30), the base body (10) having at least one through-opening (14) for leading through at least one glass fiber cable (45), which through-opening extends from a front side (V) of the base body (10) to a rear side (R) of the base body (10), a head part (13) with at least one slit (18) being arranged on the rear side (R) of the base body (10), and at least one deflecting element (20) being arranged on an outer surface of the base body (10), and the clamping body (30) being detachably connected to the base body (10).
摘要翻译：本发明涉及一种用于至少一个玻璃纤维电缆（45）的应变消除装置（1），其包括基体（10）和至少一个夹紧元件（30），所述基体（10）具有至少一个贯穿（14），其通过至少一个玻璃纤维电缆（45），所述玻璃纤维电缆（45）从所述基体（10）的前侧（V）延伸到所述基体（10）的后侧（R）），具有至少一个狭缝（18）的头部（13）布置在所述基体（10）的后侧（R）上，以及至少一个偏转元件（20）布置在所述基体基体（10），并且夹紧体（30）可拆卸地连接到基体（10）。

10. 发明申请

US20130302841A1 PROGNOSIS AND RISK ASSESSMENT OF PATIENTS WITH NON-SPECIFIC COMPLAINTS 审中-公开
标题翻译：对非特异性投诉患者的预防和风险评估
公开(公告)号：US20130302841A1
公开(公告)日：2013-11-14
申请号：US13882895
申请日：2011-10-31
申请人： Joachim Struck , Sven Giersdorf , Oliver Hartmann , Roland Bingisser , Christian Nickel
发明人： Joachim Struck , Sven Giersdorf , Oliver Hartmann , Roland Bingisser , Christian Nickel
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , G01N33/6803 , G01N2800/52 , G01N2800/56
摘要： The present invention relates to the determination of the level of marker peptides in a sample derived from a bodily fluid of a subject presenting to the emergency department with non-specific complaints.
摘要翻译：本发明涉及从具有非特异性投诉的急诊部门呈现的受试者的体液中得到的标本肽的水平的确定。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式