专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2007109804A2 EXTRACTS AND METHODS COMPRISING CINNAMON SPECIES 审中-公开
标题翻译：提取物和包含中华物种的方法
公开(公告)号：WO2007109804A2
公开(公告)日：2007-09-27
申请号：PCT/US2007/064832
申请日：2007-03-23
申请人： HERBALSCIENCE SINGAPORE PTE. LTD. , GOW, Robert, T. , SYPERT, George, W. , LI, Dan , ALBERTE, Randall, S.
发明人： GOW, Robert, T. , SYPERT, George, W. , LI, Dan , ALBERTE, Randall, S.
IPC分类号： A23L1/28 , A61K36/54 , A61P39/06 , C07C29/00 , C07C39/12 , C07C39/18 , C07C47/54 , C07C63/04 , C07D311/04 , C07H17/02
CPC分类号： C07C47/232 , A23L27/12 , A23L33/105 , A23V2002/00 , A61K36/54 , C07C29/76 , C07C31/125 , C07C33/02 , C07C33/14 , C07C33/32 , C07C35/30 , C07C45/78 , C07C47/27 , C07C47/277 , C07C47/54 , C07C51/47 , C07C67/56 , C07D311/40 , C07H17/02 , Y02P20/544 , C07C57/44 , C07C69/618 , C07C69/007 , A23V2200/15 , A23V2250/708 , A23V2250/264 , C07C69/157
摘要： The present invention relates to extracts of cinnamon species plant material prepared by supercritical CO 2 extractions methods.
摘要翻译：本发明涉及通过超临界CO 2萃取方法制备的肉桂种植物材料的提取物。

2. 发明申请

WO99020589A1 MEDICINAL USES OF PHENYLALKANOLS AND DERIVATIVES 审中-公开
标题翻译：苯丙醇和衍生物的药物用途
公开(公告)号：WO99020589A1
公开(公告)日：1999-04-29
申请号：PCT/AU1998/000870
申请日：1998-10-20
IPC分类号： A61K31/05 , A61K31/085 , A61K31/12 , C07C43/23 , C07C45/29 , C07C45/62 , C07C45/66 , C07C45/67 , C07C45/71 , C07C45/72 , C07C45/73 , C07C45/74 , C07C49/245 , C07C49/255 , C07C49/84 , C07D317/54 , C07C49/248 , C07C39/18 , C12P7/22
CPC分类号： C07D317/54 , A61K31/05 , A61K31/085 , A61K31/12 , C07C43/23 , C07C45/292 , C07C45/62 , C07C45/66 , C07C45/673 , C07C45/71 , C07C45/72 , C07C45/73 , C07C45/74 , C07C49/245 , C07C49/255 , C07C49/84 , C07C47/575 , C07C47/277
摘要： A compound of formula (I), a pharmaceutically acceptable derivative thereof, wherein Ph is a phenyl radical R1 is H, OH, OC1-4alkyl, NO2; R2 is OH, OC1-4alkyl, OC=OC1-4alkyl or OC=OPh where the Ph can be optionally substituted by halogen, C1-3 alkyl or NO2; R1 and R2 along with the two carbon atoms of the phenyl ring to which they are attached can combine to form a 5 or 6 membered heterocyclic ring comprising 1 or 2 heteroatoms selected from O, S or N; R3 is an optionally substituted hydrocarbyl radical; R4 is H, CH3, OH or =O; when R4 is =O, then the carbon to which R4 is attached is not bonded to H; W is C(=O)-CH2, CH=CH-, CH2CO, CH(OH)-CH2, C(CH3)(OH)CH2, CH2CH(OH), CH2C(CH3)OH, CO, CHOH, C(CH3)(OH), CH2, CH2CH2; X is -CH-OH, C(CH3)OH, CH2, CH(CH3) or -C=O; Y is -CH-OH, C(CH3)OH, CH2, CH(CH3) or -C=O; provided that one of W, X or Y has an OH group.
摘要翻译：式（I）化合物，其药学上可接受的衍生物，其中Ph是苯基R1是H，OH，OC1-4烷基，NO2; R 2是OH，OC 1-4烷基，OC = OC 1-4烷基或OC = OPh，其中Ph可以任选地被卤素，C 1-3烷基或NO 2取代; R1和R2与它们所连接的苯环的两个碳原子一起可以结合形成包含1或2个选自O，S或N的杂原子的5或6元杂环; R3是任选取代的烃基; R4是H，CH3，OH或= O; 当R 4为= O时，R 4所连接的碳不与H结合; W是C（= O）-CH 2，CH = CH-，CH 2 CO，CH（OH）-CH 2，C（CH 3）（OH）CH 2，CH 2 CH（OH），CH 2 C（CH 3）OH，CO，CHOH，C（ CH3）（OH），CH2，CH2CH2; X是-CH-OH，C（CH 3）OH，CH 2，CH（CH 3）或-C = O; Y是-CH-OH，C（CH 3）OH，CH 2，CH（CH 3）或-C = O; 条件是W，X或Y中的一个具有OH基团。

3. 发明申请

WO2019236962A1 CELLULAR RETINOID BINDING PROTEIN ANTAGONISTS AND USES THEREOF 审中-公开
公开(公告)号：WO2019236962A1
公开(公告)日：2019-12-12
申请号：PCT/US2019/035986
申请日：2019-06-07
申请人： CASE WESTERN RESERVE UNIVERSITY
发明人： GOLCZAK, Marcin Bernard , SILVAROLI, Josie Ann
IPC分类号： A61K31/05 , C07C39/08 , C07C39/18 , C07C39/42 , A61P27/02
摘要： A method of treating an ocular, inflammatory, immune, and/or metabolic disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a compound having a structure of formula (I).

4. 发明申请

WO2008003737A1 VERFAHREN ZUR HERSTELLUNG VON 3,3'-DIHYDROXYISORENIERATIN SOWIE NEUE ZWISCHENPRODUKTE HIERFÜR 审中-公开
标题翻译：用于生产3,3'- Dihydroxyisorenieratene和新的中间体
公开(公告)号：WO2008003737A1
公开(公告)日：2008-01-10
申请号：PCT/EP2007/056794
申请日：2007-07-05
申请人： BASF AKTIENGESELLSCHAFT , ERNST, Hansgeorg , JAEDICKE, Hagen , HENRICH, Klaus
发明人： ERNST, Hansgeorg , JAEDICKE, Hagen , HENRICH, Klaus
IPC分类号： C07C37/20 , C12P7/22 , C07C49/713 , C07C49/753 , C07C39/235 , C07C39/19 , C07C39/18 , C07C43/205
CPC分类号： C07C403/08 , C07B2200/09 , C07C37/20 , C07C37/50 , C07C39/18 , C07C403/10 , C07C2601/16 , C07F9/5442 , C07F9/5456 , C12P23/00 , C07C39/21
摘要： Die vorliegende Erfindung betrifft ein neues Verfahren zur Herstellung von 3,3'-Dihydroxyisorenieratin der Formel I, sowie neue Zwischenprodukte dieses Verfahrens.
摘要翻译：本发明涉及一种新的方法用于制备式I的3,3'- Dihydroxyisorenieratene的，以及该方法的新的中间产物。

5. 发明申请

WO2021159062A2 COMPOUNDS, COMPOSITIONS, AND METHODS TO TREAT METABOLIC DISEASE 审中-公开
公开(公告)号：WO2021159062A2
公开(公告)日：2021-08-12
申请号：PCT/US2021/017055
申请日：2021-02-08
申请人： BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
发明人： STEPHENS, Jacqueline
IPC分类号： A61K31/185 , A61K31/19 , A61K31/192 , C07C39/04 , C07C39/18 , C07C39/19 , A61K31/222 , A61K36/282 , A61K45/06 , A61P3/00
摘要： This invention is directed to compounds, compositions, and methods to treat metabolic diseases. For example, the invention is drawn to compounds identified in extracts from Artemisia scoparia for the treatment of metabolic disease.

6. 发明申请

WO2008124878A1 NON-STEROIDAL COMPOUNDS 审中-公开
标题翻译：非甾体化合物
公开(公告)号：WO2008124878A1
公开(公告)日：2008-10-23
申请号：PCT/AU2008/000519
申请日：2008-04-14
申请人： CRYPTOPHARMA PTY LTD , STEWART, Alastair , BANWELL, Martin , LEUNG, Brenda , AUGUSTINE, Anu , KITCHING, Jacki , BILSKI, Tomasz
发明人： STEWART, Alastair , BANWELL, Martin , LEUNG, Brenda , AUGUSTINE, Anu , KITCHING, Jacki , BILSKI, Tomasz
IPC分类号： C07C15/12 , C07C13/465 , C07C205/20 , A61K31/015 , C07C13/48 , C07C251/32 , A61K31/025 , C07C13/66 , C07C251/52 , A61K31/04 , C07C22/06 , C07C251/54 , A61K31/15 , C07C25/18 , C07C251/56 , A61K31/36 , C07C39/18 , C07C251/86 , A61K31/365 , C07C39/21 , C07D231/56 , A61K31/416 , C07C39/23 , C07D271/12 , A61P11/06 , C07C39/373 , C07D317/50 , A61P43/00 , C07C205/06 , C07J41/00 , C07C13/19 , C07C205/11
CPC分类号： C07C45/68 , C07C45/298 , C07C45/30 , C07C45/59 , C07C45/63 , C07C45/673 , C07C45/71 , C07C47/575 , C07C49/753 , C07C49/84 , C07C251/32 , C07C251/52 , C07C251/54 , C07C251/56 , C07C251/86 , C07D231/56 , C07D271/12 , C07D317/58
摘要： The present invention relates to non-steroidal compounds useful in the treatment of inflammatory conditions and pharmaceutical compositions comprising them. A representative example of these compounds is formula (III).
摘要翻译：本发明涉及用于治疗炎性病症的非甾体化合物和包含它们的药物组合物。这些化合物的代表性实例是式（III）。

7. 发明申请

WO2022159506A1 DEUTERATED CANNABIDIOL COMPOUNDS 审中-公开
公开(公告)号：WO2022159506A1
公开(公告)日：2022-07-28
申请号：PCT/US2022/012999
申请日：2022-01-19
申请人： MERIT THERAPEUTICS, INC.
发明人： LAUFER, Ralph , SUMMA, Vincenzo
IPC分类号： A61K31/045 , A61K31/05 , C07C39/08 , C07C39/18 , C07C39/19
摘要： This invention relates to deuterated cannabidiol compounds, methods for preparation thereof, compositions comprising the same, uses thereof, and methods comprising administration of deuterated cannabidiol compounds and at least one additional therapeutic agent, for the treatment or prevention of diseases or disorders including, but not limited to, fragile X syndrome, autism spectrum disorder, lysosomal storage diseases, leukodystrophies, Rett syndrome, osteoarthritis, musculoskeletal disorders, anorexia, emesis, pain, inflammation, multiple sclerosis, neurodegenerative disorders (Parkinson's disease, Huntington's disease, Alzheimer's disease), seizures, epilepsy, aggression, fear, phobias, anxiety, glaucoma, osteoporosis, schizophrenia, cardiovascular disorders, cancer, obesity, and metabolic syndrome-related disorders.

8. 发明申请

WO2018091551A1 BIO-STABLE CANNABINOID COMPOUNDS AND METHODS FOR ENHANCING THEIR PHYSIOLOGICAL CONCENTRATION 审中-公开
公开(公告)号：WO2018091551A1
公开(公告)日：2018-05-24
申请号：PCT/EP2017/079361
申请日：2017-11-15
申请人： FULL SPECTRUM LABORATORIES LTD
发明人： KORENTUR, Jeffrey M , PEET, Richard C , KAVARANA, Malcolm J
IPC分类号： C07C43/23 , C07C39/19 , C07C39/18 , C07C59/72 , A61P25/00 , A61K31/05
摘要： The present disclosure provides biostable cannabinoid compounds according to Formula I, and methods for synthesizing and enhancing the biological concentrations of the compounds, where R 1 , R 2 , and R 3 are defined as set forth in the disclosure.

9. 发明申请

WO01002331A1 METHOD FOR CLEAVAGE OF BISPHENOL 审中-公开
标题翻译：双酚的清除方法
公开(公告)号：WO01002331A1
公开(公告)日：2001-01-11
申请号：PCT/JP2000/004429
申请日：2000-07-04
IPC分类号： C07B61/00 , C07C37/52 , C07C37/74 , C07C39/04 , C07C39/18 , C07C39/19
CPC分类号： C07C37/52 , C07C39/04 , C07C39/19
摘要： A method for cleaving a bisphenol which comprises: (1) a cleavage step comprising feeding a mixture of a bisphenol and derivatives of chroman and flavan which are by-produced during the production of a bisphenol to a cleavage reactor and effecting cleavage reactions in the presence of a basic or acidic catalyst at 150 to 260 DEG C under a reduced pressure of 300 mmHg or less, (2) a distillation step comprising feeding the products of the cleavage reactions to a distillation column in a gaseous state and conducting a distillation at 130 to 200 DEG C under a reduced pressure of 300 mmHg or less, and (3) a reflux step comprising condensing the distillate from the distillation step, recycling a part of the resultant condensate to the distillation step at a reflux ratio of 0.01 to 3 and drawing out the rest of the condensate to the outside of the system. The method can be employed for producing a product containing isopropenyl phenol and phenol with high purity.
摘要翻译：一种用于切割双酚的方法，其包括：（1）切割步骤，包括将在双酚生产期间副产的双酚和苯并二氢吡喃和黄烷的衍生物的混合物进料到裂解反应器中并在存在下进行裂解反应的碱性或酸性催化剂在150至260℃的压力为300mmHg或更低的压力下进行的蒸馏步骤;（2）蒸馏步骤，包括将裂解反应产物以气态进料至蒸馏塔，并在130℃下进行蒸馏在300mmHg或更低的减压下至200℃，和（3）回流步骤，其包括将蒸馏步骤的馏出物冷凝，将一部分所得的冷凝物以0.01至3的回流比循环至蒸馏步骤;以及将其余的冷凝液抽出到系统的外部。该方法可用于生产含有高纯度的异丙烯基苯酚和苯酚的产物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式