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    • 3. 发明申请
    • APPARATUSES AND METHODS FOR GENERATING AND MEASURING ENVIRONMENTAL LEVELS OF ALLERGENS
    • 产生和测量过敏原环境水平的方法和方法
    • WO2016083948A2
    • 2016-06-02
    • PCT/IB2015/058902
    • 2015-11-17
    • NESTEC SA
    • NELSON, RichardSATYARAJ, Ebenezer
    • A61G10/00G01N33/68A62B31/00
    • G01N33/566A61B5/411A61B5/6889A61G10/02G01N33/68G01N2333/24G01N2333/46
    • The present disclosure provides an apparatus comprising an air circulating device, an allergen source comprising an allergen, and a housing. The housing can be collapsible, portable, disposable and configurable. The present disclosure also provides a method comprising positioning an allergen source comprising an allergen in a chamber, distributing at least a portion of the allergen from the allergen source within the chamber, and collecting at least a portion of the distributed allergen. In an embodiment, the level of the shed allergen can be used to measure the effectiveness of various measures implemented to reduce airborne Fel d1 that is emitted from soiled cat litter. In another embodiment, the allergen can be introduced at a desired level in the chamber, and the resultant symptoms of a subject (e.g. a human) within the chamber can be identified and correlated with the amount of allergen.
    • 本公开提供了一种包括空气循环装置,包含变应原的变应原源和壳体的装置。 外壳可折叠,便携,一次性和可配置。 本公开还提供了一种方法,其包括将包含过敏原的变应原源定位在室中,将来自变应原源的变应原的至少一部分分配在室内,以及收集分布式过敏原的至少一部分。 在一个实施方案中,棚棚过敏原的水平可用于测量为减少从污染的猫砂发出的空气中的Fel d1所实施的各种措施的有效性。 在另一个实施方案中,可以在室中以期望的水平引入变应原,并且可以鉴定室内受试者(例如人)的最终症状并与变应原的量相关。
    • 7. 发明申请
    • APPARATUSES AND METHODS FOR GENERATING AND MEASURING ENVIRONMENTAL LEVELS OF ALLERGENS
    • 用于产生和测量环氧化物水平的装置和方法
    • WO2016083948A3
    • 2016-08-18
    • PCT/IB2015058902
    • 2015-11-17
    • NESTEC SA
    • NELSON RICHARDSATYARAJ EBENEZER
    • A61G10/00A62B31/00G01N33/68
    • G01N33/566G01N33/68G01N2333/24G01N2333/46
    • The present disclosure provides an apparatus comprising an air circulating device, an allergen source comprising an allergen, and a housing. The housing can be collapsible, portable, disposable and configurable. The present disclosure also provides a method comprising positioning an allergen source comprising an allergen in a chamber, distributing at least a portion of the allergen from the allergen source within the chamber, and collecting at least a portion of the distributed allergen. In an embodiment, the level of the shed allergen can be used to measure the effectiveness of various measures implemented to reduce airborne Fel d1 that is emitted from soiled cat litter. In another embodiment, the allergen can be introduced at a desired level in the chamber, and the resultant symptoms of a subject (e.g. a human) within the chamber can be identified and correlated with the amount of allergen.
    • 本公开提供了一种装置,其包括空气循环装置,包含过敏原的过敏原源和外壳。 外壳可以折叠,便携,一次性和可配置。 本发明还提供了一种方法,包括将包含过敏原的过敏原源定位在腔室中,将来自过敏源的至少一部分过敏原分布在腔室内,并收集至少一部分分布的过敏原。 在一个实施例中,可以使用棚内过敏原的水平来测量为减少污染猫砂排放的浮游Fel d1而实施的各种措施的有效性。 在另一个实施方案中,过敏原可以在腔室中以期望的水平被引入,并且腔室内的受试者(例如人)的所得症状可以被识别并且与过敏原的量相关联。
    • 10. 发明申请
    • METHOD FOR DETECTING SUSCEPTIBILITY OF MICROORGANISMS TO CHEMICAL AGENTS
    • 检测微生物对化学试剂的不良性的方法
    • WO2013182647A2
    • 2013-12-12
    • PCT/EP2013061719
    • 2013-06-06
    • IDMIC SA
    • GOVORUN VADIMILINA ELENAPODOPLELOV ALEXEI
    • C12Q1/18G01N2333/24G01N2333/245G01N2560/00
    • The invention relates to a method for detecting susceptibility of microorganisms to chemical agents, wherein microorganisms are cultured in a nutrient medium broth together with a chemical agent or antibiotic followed by processing of the medium in which microbial cell fragments may be dispensed due to cell lysis, and following that, the microorganism-free supernatant is analyzed on its protein components and compared to control or reference samples. The method comprises the addition of a quantity of microbial cells to a liquid nutrient medium supplemented with a quantity of an enhancer specific for a certain group (genus or family) of microorganisms to the nutrient medium. The microorganisms are pre-incubated and after addition of a quantity of antibiotic to the nutrient medium the microorganisms are again incubated. The cells are removed from the incubated nutrient medium to yield the supernatant. The proteins within the supernatant are extracted by adding alcohol followed by isolation of the proteins. The protein sediment is used to acquire a mass spectrum for comparison with a reference mass spectrum.
    • 本发明涉及一种用于检测微生物对化学试剂的敏感性的方法,其中将微生物与营养培养基肉汤一起在化学试剂或抗生素中培养,然后加工由于细胞裂解可分泌微生物细胞碎片的培养基, 并且随后,对其无微生物的上清液进行蛋白质组分的分析,并与对照或参照样品进行比较。 该方法包括将一定数量的微生物细胞添加到补充有一定数量的特定微生物群(属或家族)的增强子的液体营养培养基中的营养培养基中。 微生物被预培养,并且在向营养培养基中加入一定数量的抗生素后,再次温育微生物。 从培养的营养培养基中除去细胞以产生上清液。 通过加入醇提取上清液中的蛋白质,然后分离蛋白质。 蛋白质沉淀物用于获得与参考质谱图进行比较的质谱。